-
1
-
-
79960564054
-
Combination Therapy: The Next Opportunity and Challenge of Medicine
-
Ascierto, P. A.; Marincola, F. M. Combination Therapy: The Next Opportunity and Challenge of Medicine J. Transl. Med. 2011, 9, 115
-
(2011)
J. Transl. Med.
, vol.9
, pp. 115
-
-
Ascierto, P.A.1
Marincola, F.M.2
-
2
-
-
84864512253
-
Combination Anastrozole and Fulvestrant in Metastatic Breast Cancer
-
Mehta, R. S.; Barlow, W. E.; Albain, K. S.; Vandenberg, T. A.; Dakhil, S. R.; Tirumali, N. R.; Lew, D. L.; Hayes, D. F.; Gralow, J. R.; Livingston, R. B.; Hortobagyi, G. N. Combination Anastrozole and Fulvestrant in Metastatic Breast Cancer N. Engl. J. Med. 2012, 367, 435-444
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 435-444
-
-
Mehta, R.S.1
Barlow, W.E.2
Albain, K.S.3
Vandenberg, T.A.4
Dakhil, S.R.5
Tirumali, N.R.6
Lew, D.L.7
Hayes, D.F.8
Gralow, J.R.9
Livingston, R.B.10
Hortobagyi, G.N.11
-
3
-
-
0032423157
-
Combination Chemotherapy versus Single-Agent Therapy as First- and Second-Line Treatment in Metastatic Breast Cancer: A Prospective Randomized Trial
-
Joensuu, H.; Holli, K.; Heikkinen, M.; Suonio, E.; Aro, A. R.; Hietanen, P.; Huovinen, R. Combination Chemotherapy versus Single-Agent Therapy as First- and Second-Line Treatment in Metastatic Breast Cancer: a Prospective Randomized Trial J. Clin. Oncol. 1998, 16, 3720-3730
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 3720-3730
-
-
Joensuu, H.1
Holli, K.2
Heikkinen, M.3
Suonio, E.4
Aro, A.R.5
Hietanen, P.6
Huovinen, R.7
-
4
-
-
36849067019
-
Nanocarriers as an Emerging Platform for Cancer Therapy
-
Peer, D.; Karp, J. M.; Hong, S.; Farokhzad, O. C.; Margalit, R.; Langer, R. Nanocarriers as an Emerging Platform for Cancer Therapy Nat. Nanotechnol. 2007, 2, 751-760
-
(2007)
Nat. Nanotechnol.
, vol.2
, pp. 751-760
-
-
Peer, D.1
Karp, J.M.2
Hong, S.3
Farokhzad, O.C.4
Margalit, R.5
Langer, R.6
-
5
-
-
77649185057
-
Targeted Delivery of RGD-Modified Liposomes Encapsulating both Combretastatin A-4 and Doxorubicin for Tumor Therapy: In Vitro and in Vivo Studies
-
Zhang, Y. F.; Wang, J. C.; Bian, D. Y.; Zhang, X.; Zhang, Q. Targeted Delivery of RGD-Modified Liposomes Encapsulating both Combretastatin A-4 and Doxorubicin for Tumor Therapy: In Vitro and in Vivo Studies Eur. J. Pharm. Biopharm. 2010, 74, 467-473
-
(2010)
Eur. J. Pharm. Biopharm.
, vol.74
, pp. 467-473
-
-
Zhang, Y.F.1
Wang, J.C.2
Bian, D.Y.3
Zhang, X.4
Zhang, Q.5
-
6
-
-
80052386569
-
Enhanced Anti-Tumor Efficacy by Co-Delivery of Doxorubicin and Paclitaxel with Amphiphilic Methoxy PEG-PLGA Copolymer Nanoparticles
-
Wang, H.; Zhao, Y.; Wu, Y.; Hu, Y. L.; Nan, K.; Nie, G.; Chen, H. Enhanced Anti-Tumor Efficacy by Co-Delivery of Doxorubicin and Paclitaxel with Amphiphilic Methoxy PEG-PLGA Copolymer Nanoparticles Biomaterials 2011, 32, 8281-8290
-
(2011)
Biomaterials
, vol.32
, pp. 8281-8290
-
-
Wang, H.1
Zhao, Y.2
Wu, Y.3
Hu, Y.L.4
Nan, K.5
Nie, G.6
Chen, H.7
-
7
-
-
84880814226
-
Smart pH-Sensitive and Temporal-Controlled Polymeric Micelles for Effective Combination Therapy of Doxorubicin and Disulfiram
-
Duan, X.; Xiao, J.; Yin, Q.; Zhang, Z.; Yu, H.; Mao, S.; Li, Y. Smart pH-Sensitive and Temporal-Controlled Polymeric Micelles for Effective Combination Therapy of Doxorubicin and Disulfiram ACS Nano 2013, 7, 5858-5869
-
(2013)
ACS Nano
, vol.7
, pp. 5858-5869
-
-
Duan, X.1
Xiao, J.2
Yin, Q.3
Zhang, Z.4
Yu, H.5
Mao, S.6
Li, Y.7
-
8
-
-
84883261319
-
One-Pot Construction of Functional Mesoporous Silica Nanoparticles for the Tumor-Acidity-Activated Synergistic Chemotherapy of Glioblastoma
-
Li, Z.-Y.; Liu, Y.; Wang, X.-Q.; Liu, L.-H.; Hu, J.-J.; Luo, G.-F.; Chen, W.-H.; Rong, L.; Zhang, X.-Z. One-Pot Construction of Functional Mesoporous Silica Nanoparticles for the Tumor-Acidity-Activated Synergistic Chemotherapy of Glioblastoma ACS Appl. Mater. Interfaces 2013, 5, 7995-8001
-
(2013)
ACS Appl. Mater. Interfaces
, vol.5
, pp. 7995-8001
-
-
Li, Z.-Y.1
Liu, Y.2
Wang, X.-Q.3
Liu, L.-H.4
Hu, J.-J.5
Luo, G.-F.6
Chen, W.-H.7
Rong, L.8
Zhang, X.-Z.9
-
9
-
-
84905449941
-
Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer
-
Wang, H.; Li, F.; Du, C.; Wang, H.; Mahato, R. I.; Huang, Y. Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer Mol. Pharmaceutics 2014, 11, 2600-2611
-
(2014)
Mol. Pharmaceutics
, vol.11
, pp. 2600-2611
-
-
Wang, H.1
Li, F.2
Du, C.3
Wang, H.4
Mahato, R.I.5
Huang, Y.6
-
10
-
-
75749144204
-
Structural and Chemical Aspects of HPMA Copolymers as Drug Carriers
-
Ulbrich, K.; Šubr, V. Structural and Chemical Aspects of HPMA Copolymers as Drug Carriers Adv. Drug Delivery Rev. 2010, 62, 150-166
-
(2010)
Adv. Drug Delivery Rev.
, vol.62
, pp. 150-166
-
-
Ulbrich, K.1
Šubr, V.2
-
11
-
-
84858228160
-
Polymeric Conjugates for Drug Delivery
-
Larson, N.; Ghandehari, H. Polymeric Conjugates for Drug Delivery Chem. Mater. 2012, 24, 840-853
-
(2012)
Chem. Mater.
, vol.24
, pp. 840-853
-
-
Larson, N.1
Ghandehari, H.2
-
13
-
-
84873278168
-
Polymer-Drug Conjugates: Origins, Progress to Date and Future Directions
-
Kopeček, J. Polymer-Drug Conjugates: Origins, Progress to Date and Future Directions Adv. Drug Delivery Rev. 2013, 65, 49-59
-
(2013)
Adv. Drug Delivery Rev.
, vol.65
, pp. 49-59
-
-
Kopeček, J.1
-
14
-
-
67349247858
-
HPMA-Based Polymer Conjugates with Drug Combination
-
Krakovicova, H.; Etrych, T.; Ulbrich, K. HPMA-Based Polymer Conjugates with Drug Combination Eur. J. Pharm. Sci. 2009, 37, 405-412
-
(2009)
Eur. J. Pharm. Sci.
, vol.37
, pp. 405-412
-
-
Krakovicova, H.1
Etrych, T.2
Ulbrich, K.3
-
15
-
-
79957634222
-
Synergistic Effect of HPMA Copolymer-Bound Doxorubicin and Dexamethasone in Vivo on Mouse Lymphomas
-
Kostková, H.; Etrych, T.; Říhová, B.; Ulbrich, K. Synergistic Effect of HPMA Copolymer-Bound Doxorubicin and Dexamethasone in Vivo on Mouse Lymphomas J. Bioact. Compat. Polym. 2011, 26, 270-286
-
(2011)
J. Bioact. Compat. Polym.
, vol.26
, pp. 270-286
-
-
Kostková, H.1
Etrych, T.2
Říhová, B.3
Ulbrich, K.4
-
16
-
-
67349283045
-
Simultaneous Delivery of Doxorubicin and Gemcitabine to Tumors in Vivo Using Prototypic Polymeric Drug Carriers
-
Lammers, T.; Subr, V.; Ulbrich, K.; Peschke, P.; Huber, P. E.; Hennink, W. E.; Storm, G. Simultaneous Delivery of Doxorubicin and Gemcitabine to Tumors in Vivo Using Prototypic Polymeric Drug Carriers Biomaterials 2009, 30, 3466-3475
-
(2009)
Biomaterials
, vol.30
, pp. 3466-3475
-
-
Lammers, T.1
Subr, V.2
Ulbrich, K.3
Peschke, P.4
Huber, P.E.5
Hennink, W.E.6
Storm, G.7
-
17
-
-
84887161387
-
HPMA Copolymer-Based Combination Therapy Toxic to Both Prostate Cancer Stem/Progenitor Cells and Differentiated Cells Induces Durable Anti-Tumor Effects
-
Zhou, Y.; Yang, J.; Rhim, J. S.; Kopeček, J. HPMA Copolymer-Based Combination Therapy Toxic to Both Prostate Cancer Stem/Progenitor Cells and Differentiated Cells Induces Durable Anti-Tumor Effects J. Controlled Release 2013, 172, 946-953
-
(2013)
J. Controlled Release
, vol.172
, pp. 946-953
-
-
Zhou, Y.1
Yang, J.2
Rhim, J.S.3
Kopeček, J.4
-
18
-
-
84890560256
-
HPMA Copolymer Conjugates of DOX and Mitomycin C for Combination Therapy: Physicochemical Characterization, Cytotoxic Effects, Combination Index Analysis, and Anti-Tumor Efficacy
-
Kostkova, H.; Etrych, T.; Rihova, B.; Kostka, L.; Starovoytova, L.; Kovar, M.; Ulbrich, K. HPMA Copolymer Conjugates of DOX and Mitomycin C for Combination Therapy: Physicochemical Characterization, Cytotoxic Effects, Combination Index Analysis, and Anti-Tumor Efficacy Macromol. Biosci. 2013, 13, 1648-1660
-
(2013)
Macromol. Biosci.
, vol.13
, pp. 1648-1660
-
-
Kostkova, H.1
Etrych, T.2
Rihova, B.3
Kostka, L.4
Starovoytova, L.5
Kovar, M.6
Ulbrich, K.7
-
19
-
-
6044243650
-
Hedgehog Signalling in Prostate Regeneration, Neoplasia and Metastasis
-
Karhadkar, S. S.; Bova, G. S.; Abdallah, N.; Dhara, S.; Gardner, D.; Maitra, A.; Isaacs, J. T.; Berman, D. M.; Beachy, P. A. Hedgehog Signalling in Prostate Regeneration, Neoplasia and Metastasis Nature 2004, 431, 707-712
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
20
-
-
70349978292
-
Combination Therapy: Opportunities and Challenges for Polymer-Drug Conjugates as Anticancer Nanomedicines
-
Greco, F.; Vicent, M. J. Combination Therapy: Opportunities and Challenges for Polymer-Drug Conjugates as Anticancer Nanomedicines Adv. Drug Delivery Rev. 2009, 61, 1203-1213
-
(2009)
Adv. Drug Delivery Rev.
, vol.61
, pp. 1203-1213
-
-
Greco, F.1
Vicent, M.J.2
-
21
-
-
75749134040
-
Improving the Efficacy of Combined Modality Anticancer Therapy Using HPMA Copolymer-Based Nanomedicine Formulations
-
Lammers, T. Improving the Efficacy of Combined Modality Anticancer Therapy Using HPMA Copolymer-Based Nanomedicine Formulations Adv. Drug Delivery Rev. 2010, 62, 203-230
-
(2010)
Adv. Drug Delivery Rev.
, vol.62
, pp. 203-230
-
-
Lammers, T.1
-
22
-
-
75749149269
-
HPMA Copolymers: Origins, Early Developments, Present, and Future
-
Kopeček, J.; Kopečková, P. HPMA Copolymers: Origins, Early Developments, Present, and Future Adv. Drug Delivery Rev. 2010, 62, 122-149
-
(2010)
Adv. Drug Delivery Rev.
, vol.62
, pp. 122-149
-
-
Kopeček, J.1
Kopečková, P.2
-
23
-
-
77956651717
-
Polymeric Nanomedicines for Image-Guided Drug Delivery and Tumor-Targeted Combination Therapy
-
Lammers, T.; Subr, V.; Ulbrich, K.; Hennink, W. E.; Storm, G.; Kiessling, F. Polymeric Nanomedicines for Image-Guided Drug Delivery and Tumor-Targeted Combination Therapy Nano Today 2010, 5, 197-212
-
(2010)
Nano Today
, vol.5
, pp. 197-212
-
-
Lammers, T.1
Subr, V.2
Ulbrich, K.3
Hennink, W.E.4
Storm, G.5
Kiessling, F.6
-
24
-
-
75749098035
-
HPMA Copolymer-Cyclic RGD Conjugates for Tumor Targeting
-
Pike, D. B.; Ghandehari, H. HPMA Copolymer-Cyclic RGD Conjugates for Tumor Targeting Adv. Drug Delivery Rev. 2010, 62, 167-183
-
(2010)
Adv. Drug Delivery Rev.
, vol.62
, pp. 167-183
-
-
Pike, D.B.1
Ghandehari, H.2
-
25
-
-
79960720473
-
Glycosylation, Galectins, and Cellular Signaling
-
Boscher, C.; Dennis, J. W.; Nabi, I. R. Glycosylation, Galectins, and Cellular Signaling Curr. Opin. Cell Biol. 2011, 23, 383-392
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 383-392
-
-
Boscher, C.1
Dennis, J.W.2
Nabi, I.R.3
-
26
-
-
84855754743
-
Treatment of Prostate Carcinoma with (Galectin-3)-Targeted HPMA Copolymer-(G3-C12)-5-Fluorouracil Conjugates
-
Yang, Y.; Zhou, Z.; He, S.; Fan, T.; Jin, Y.; Zhu, X.; Chen, C.; Zhang, Z.-r.; Huang, Y. Treatment of Prostate Carcinoma with (Galectin-3)-Targeted HPMA Copolymer-(G3-C12)-5-Fluorouracil Conjugates Biomaterials 2012, 33, 2260-2271
-
(2012)
Biomaterials
, vol.33
, pp. 2260-2271
-
-
Yang, Y.1
Zhou, Z.2
He, S.3
Fan, T.4
Jin, Y.5
Zhu, X.6
Chen, C.7
Zhang, Z.-R.8
Huang, Y.9
-
27
-
-
84907969377
-
Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N -(2-Hydroxypropyl)methacrylamide Copolymers
-
Yang, Y.; Li, L.; Zhou, Z.; Yang, Q.; Liu, C.; Huang, Y. Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N -(2-Hydroxypropyl)methacrylamide Copolymers Mol. Pharmaceutics 2014, 11, 3251-3260
-
(2014)
Mol. Pharmaceutics
, vol.11
, pp. 3251-3260
-
-
Yang, Y.1
Li, L.2
Zhou, Z.3
Yang, Q.4
Liu, C.5
Huang, Y.6
-
28
-
-
0029038757
-
Mechanism of Action of DNA Topoisomerase Inhibitors
-
Binaschi, M.; Zunino, F.; Capranico, G. Mechanism of Action of DNA Topoisomerase Inhibitors Stem Cells 1995, 13, 369-379
-
(1995)
Stem Cells
, vol.13
, pp. 369-379
-
-
Binaschi, M.1
Zunino, F.2
Capranico, G.3
-
29
-
-
77951086882
-
5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity
-
Vincent, J.; Mignot, G.; Chalmin, F.; Ladoire, S.; Bruchard, M.; Chevriaux, A.; Martin, F.; Apetoh, L.; Rebe, C.; Ghiringhelli, F. 5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity Cancer Res. 2010, 70, 3052-3061
-
(2010)
Cancer Res.
, vol.70
, pp. 3052-3061
-
-
Vincent, J.1
Mignot, G.2
Chalmin, F.3
Ladoire, S.4
Bruchard, M.5
Chevriaux, A.6
Martin, F.7
Apetoh, L.8
Rebe, C.9
Ghiringhelli, F.10
-
30
-
-
0035868906
-
Doxorubicin and Paclitaxel versus Fluorouracil, Doxorubicin, and Cyclophosphamide as First-Line Therapy for Women with Metastatic Breast Cancer: Final Results of a Randomized Phase III Multicenter Trial
-
Central and Eastern Europe and Israel Pacitaxel Breast Cancer Study Group
-
Jassem, J.; Pienkowski, T.; Pluzanska, A.; Jelic, S.; Gorbunova, V.; Mrsic-Krmpotic, Z.; Berzins, J.; Nagykalnai, T.; Wigler, N.; Renard, J.; Munier, S.; Weil, C.; Central and Eastern Europe and Israel Pacitaxel Breast Cancer Study Group Doxorubicin and Paclitaxel versus Fluorouracil, Doxorubicin, and Cyclophosphamide as First-Line Therapy for Women with Metastatic Breast Cancer: Final Results of a Randomized Phase III Multicenter Trial J. Clin. Oncol. 2001, 19, 1707-1715
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1707-1715
-
-
Jassem, J.1
Pienkowski, T.2
Pluzanska, A.3
Jelic, S.4
Gorbunova, V.5
Mrsic-Krmpotic, Z.6
Berzins, J.7
Nagykalnai, T.8
Wigler, N.9
Renard, J.10
Munier, S.11
Weil, C.12
-
31
-
-
0018972967
-
5-Fluorouracil, Adriamycin, and Mitomycin-C (FAM) Chemotherapy for Advanced Adenocarcinoma of the Pancreas
-
Smith, F. P.; Hoth, D. F.; Levin, B.; Karlin, D. A.; MacDonald, J. S.; Woolley, P. V., III; Schein, P. S. 5-Fluorouracil, Adriamycin, and Mitomycin-C (FAM) Chemotherapy for Advanced Adenocarcinoma of the Pancreas Cancer 1980, 46, 2014-2018
-
(1980)
Cancer
, vol.46
, pp. 2014-2018
-
-
Smith, F.P.1
Hoth, D.F.2
Levin, B.3
Karlin, D.A.4
MacDonald, J.S.5
Woolley, P.V.6
Schein, P.S.7
-
32
-
-
84901649927
-
Hydrazone-Bearing PMMA-Functionalized Magnetic Nanocubes as pH-Responsive Drug Carriers for Remotely Targeted Cancer Therapy in Vitro and in Vivo
-
Ding, X.; Liu, Y.; Li, J.; Luo, Z.; Hu, Y.; Zhang, B.; Liu, J.; Zhou, J.; Cai, K. Hydrazone-Bearing PMMA-Functionalized Magnetic Nanocubes as pH-Responsive Drug Carriers for Remotely Targeted Cancer Therapy in Vitro and in Vivo ACS Appl. Mater. Interfaces 2014, 6, 7395-7407
-
(2014)
ACS Appl. Mater. Interfaces
, vol.6
, pp. 7395-7407
-
-
Ding, X.1
Liu, Y.2
Li, J.3
Luo, Z.4
Hu, Y.5
Zhang, B.6
Liu, J.7
Zhou, J.8
Cai, K.9
-
33
-
-
0342316475
-
Polymeric Drugs Based on Conjugates of Synthetic and Natural Macromolecules. I. Synthesis and Physico-Chemical Characterisation
-
Ulbrich, K.; Subr, V.; Strohalm, J.; Plocova, D.; Jelinkova, M.; Rihova, B. Polymeric Drugs Based on Conjugates of Synthetic and Natural Macromolecules. I. Synthesis and Physico-Chemical Characterisation J. Controlled Release 2000, 64, 63-79
-
(2000)
J. Controlled Release
, vol.64
, pp. 63-79
-
-
Ulbrich, K.1
Subr, V.2
Strohalm, J.3
Plocova, D.4
Jelinkova, M.5
Rihova, B.6
-
34
-
-
49549105573
-
N -(2-Hydroxypropyl) Methacrylamide-Based Polymer Conjugates with pH-Controlled Activation of Doxorubicin. I. New Synthesis, Physicochemical Characterization and Preliminary Biological Evaluation
-
Etrych, T.; Mrkvan, T.; Chytil, P.; Koňák, Č.; Říhová, B.; Ulbrich, K. N -(2-Hydroxypropyl) Methacrylamide-Based Polymer Conjugates with pH-Controlled Activation of Doxorubicin. I. New Synthesis, Physicochemical Characterization and Preliminary Biological Evaluation J. Appl. Polym. Sci. 2008, 109, 3050-3061
-
(2008)
J. Appl. Polym. Sci.
, vol.109
, pp. 3050-3061
-
-
Etrych, T.1
Mrkvan, T.2
Chytil, P.3
Koňák Č.4
Říhová, B.5
Ulbrich, K.6
-
35
-
-
0000932483
-
Aminolyses of Monomeric and Polymeric 4-Nitrophenyl Esters of N -Methacryloylamino Acids
-
Rejmanová, P.; Labský, J.; Kopeček, J. Aminolyses of Monomeric and Polymeric 4-Nitrophenyl Esters of N -Methacryloylamino Acids Macromol. Chem. Phys. 1977, 178, 2159-2168
-
(1977)
Macromol. Chem. Phys.
, vol.178
, pp. 2159-2168
-
-
Rejmanová, P.1
Labský, J.2
Kopeček, J.3
-
36
-
-
38649143644
-
Synthesis and Characterization of HPMA Copolymer-5-FU Conjugates
-
Yuan, F.; Chen, F.; Xiang, Q. Y.; Qin, X.; Zhang, Z. R.; Huang, Y. Synthesis and Characterization of HPMA Copolymer-5-FU Conjugates Chin. Chem. Lett. 2008, 19, 137-140
-
(2008)
Chin. Chem. Lett.
, vol.19
, pp. 137-140
-
-
Yuan, F.1
Chen, F.2
Xiang, Q.Y.3
Qin, X.4
Zhang, Z.R.5
Huang, Y.6
-
37
-
-
0001319102
-
N -(2-hydroxypropyl) Methacrylamide Copolymers Containing Pendant Saccharide Moieties: Synthesis and Bioadhesive Properties
-
Rathi, R. C.; Kopečková, P.; Říhová, B.; Kopeček, J. N -(2-hydroxypropyl) Methacrylamide Copolymers Containing Pendant Saccharide Moieties: Synthesis and Bioadhesive Properties J. Polym. Sci., Part A: Polym. Chem. 1991, 29, 1895-1902
-
(1991)
J. Polym. Sci., Part A: Polym. Chem.
, vol.29
, pp. 1895-1902
-
-
Rathi, R.C.1
Kopečková, P.2
Říhová, B.3
Kopeček, J.4
-
38
-
-
54949139950
-
In Vitro Cytotoxicity, in Vivo Biodistribution and Antitumor Activity of HPMA Copolymer-5-Fluorouracil Conjugates
-
Yuan, F.; Qin, X.; Zhou, D.; Xiang, Q. Y.; Wang, M. T.; Zhang, Z. R.; Huang, Y. In Vitro Cytotoxicity, in Vivo Biodistribution and Antitumor Activity of HPMA Copolymer-5-Fluorouracil Conjugates Eur. J. Pharm. Biopharm. 2008, 70, 770-776
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 770-776
-
-
Yuan, F.1
Qin, X.2
Zhou, D.3
Xiang, Q.Y.4
Wang, M.T.5
Zhang, Z.R.6
Huang, Y.7
-
39
-
-
0035907178
-
New HPMA Copolymers Containing Doxorubicin Bound via pH-Sensitive Linkage: Synthesis and Preliminary in Vitro and in Vivo Biological Properties
-
Etrych, T.; Jelínková, M.; Říhová, B.; Ulbrich, K. New HPMA Copolymers Containing Doxorubicin Bound via pH-Sensitive Linkage: Synthesis and Preliminary in Vitro and in Vivo Biological Properties J. Controlled Release 2001, 73, 89-102
-
(2001)
J. Controlled Release
, vol.73
, pp. 89-102
-
-
Etrych, T.1
Jelínková, M.2
Říhová, B.3
Ulbrich, K.4
-
40
-
-
84873332319
-
Synthesis and Evaluation of a Backbone Biodegradable Multiblock HPMA Copolymer Nanocarrier for the Systemic Delivery of Paclitaxel
-
Zhang, R.; Luo, K.; Yang, J.; Sima, M.; Sun, Y.; Janát-Amsbury, M. M.; Kopeček, J. Synthesis and Evaluation of a Backbone Biodegradable Multiblock HPMA Copolymer Nanocarrier for the Systemic Delivery of Paclitaxel J. Controlled Release 2013, 166, 66-74
-
(2013)
J. Controlled Release
, vol.166
, pp. 66-74
-
-
Zhang, R.1
Luo, K.2
Yang, J.3
Sima, M.4
Sun, Y.5
Janát-Amsbury, M.M.6
Kopeček, J.7
-
41
-
-
79954632423
-
Biodegradable Star HPMA Polymer Conjugates of Doxorubicin for Passive Tumor Targeting
-
Etrych, T.; Strohalm, J.; Chytil, P.; Černoch, P.; Starovoytova, L.; Pechar, M.; Ulbrich, K. Biodegradable Star HPMA Polymer Conjugates of Doxorubicin for Passive Tumor Targeting Eur. J. Pharm. Sci. 2011, 42, 527-539
-
(2011)
Eur. J. Pharm. Sci.
, vol.42
, pp. 527-539
-
-
Etrych, T.1
Strohalm, J.2
Chytil, P.3
Černoch, P.4
Starovoytova, L.5
Pechar, M.6
Ulbrich, K.7
-
42
-
-
80455168058
-
Tailor-Made Dual pH-Sensitive Polymer-Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery
-
Du, J. Z.; Du, X. J.; Mao, C. Q.; Wang, J. Tailor-Made Dual pH-Sensitive Polymer-Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery J. Am. Chem. Soc. 2011, 133, 17560-17563
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 17560-17563
-
-
Du, J.Z.1
Du, X.J.2
Mao, C.Q.3
Wang, J.4
-
43
-
-
84906076240
-
Peptide Dendrimer-Doxorubicin Conjugate-Based Nanoparticles as an Enzyme-Responsive Drug Delivery System for Cancer Therapy
-
Zhang, C.; Pan, D.; Luo, K.; She, W.; Guo, C.; Yang, Y.; Gu, Z. Peptide Dendrimer-Doxorubicin Conjugate-Based Nanoparticles as an Enzyme-Responsive Drug Delivery System for Cancer Therapy Adv. Healthcare Mater. 2014, 3, 1299-1308
-
(2014)
Adv. Healthcare Mater.
, vol.3
, pp. 1299-1308
-
-
Zhang, C.1
Pan, D.2
Luo, K.3
She, W.4
Guo, C.5
Yang, Y.6
Gu, Z.7
-
44
-
-
76549129820
-
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
-
Chou, T. C. Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method Cancer Res. 2010, 70, 440-446
-
(2010)
Cancer Res.
, vol.70
, pp. 440-446
-
-
Chou, T.C.1
-
45
-
-
84875861861
-
Doxorubicin Delivery to 3D Multicellular Spheroids and Tumors Based on Boronic Acid-Rich Chitosan Nanoparticles
-
Wang, X.; Zhen, X.; Wang, J.; Zhang, J.; Wu, W.; Jiang, X. Doxorubicin Delivery to 3D Multicellular Spheroids and Tumors Based on Boronic Acid-Rich Chitosan Nanoparticles Biomaterials 2013, 34, 4667-4679
-
(2013)
Biomaterials
, vol.34
, pp. 4667-4679
-
-
Wang, X.1
Zhen, X.2
Wang, J.3
Zhang, J.4
Wu, W.5
Jiang, X.6
-
46
-
-
39749166975
-
DNA Repair Pathways as Targets for Cancer Therapy
-
Helleday, T.; Petermann, E.; Lundin, C.; Hodgson, B.; Sharma, R. A. DNA Repair Pathways as Targets for Cancer Therapy Nat. Rev. Cancer 2008, 8, 193-204
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
47
-
-
33746842309
-
DNA Damage-Dependent Cell Cycle Checkpoints and Genomic Stability
-
Ishikawa, K.; Ishii, H.; Saito, T. DNA Damage-Dependent Cell Cycle Checkpoints and Genomic Stability DNA Cell Biol. 2006, 25, 406-411
-
(2006)
DNA Cell Biol.
, vol.25
, pp. 406-411
-
-
Ishikawa, K.1
Ishii, H.2
Saito, T.3
-
48
-
-
84923217162
-
Targeting Apoptosis for Anticancer Therapy
-
Fulda, S. Targeting Apoptosis for Anticancer Therapy Semin. Cancer Biol. 2015, 31, 84-88
-
(2015)
Semin. Cancer Biol.
, vol.31
, pp. 84-88
-
-
Fulda, S.1
-
49
-
-
0033527063
-
Involvement of Caspase 3-Activated DNase in Internucleosomal DNA Cleavage Induced by Diverse Apoptotic Stimuli
-
McIlroy, D.; Sakahira, H.; Talanian, R. V.; Nagata, S. Involvement of Caspase 3-Activated DNase in Internucleosomal DNA Cleavage Induced by Diverse Apoptotic Stimuli Oncogene 1999, 18, 4401-4408
-
(1999)
Oncogene
, vol.18
, pp. 4401-4408
-
-
McIlroy, D.1
Sakahira, H.2
Talanian, R.V.3
Nagata, S.4
-
50
-
-
63449105617
-
Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
-
AshaRani, P. V.; Low Kah Mun, G.; Hande, M. P.; Valiyaveettil, S. Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells ACS Nano 2009, 3, 279-290
-
(2009)
ACS Nano
, vol.3
, pp. 279-290
-
-
Asharani, P.V.1
Low Kah Mun, G.2
Hande, M.P.3
Valiyaveettil, S.4
-
51
-
-
84862698355
-
Drug Targeting to Tumors: Principles, Pitfalls and (Pre-) Clinical Progress
-
Lammers, T.; Kiessling, F.; Hennink, W. E.; Storm, G. Drug Targeting to Tumors: Principles, Pitfalls and (Pre-) Clinical Progress J. Controlled Release 2012, 161, 175-187
-
(2012)
J. Controlled Release
, vol.161
, pp. 175-187
-
-
Lammers, T.1
Kiessling, F.2
Hennink, W.E.3
Storm, G.4
-
52
-
-
84899995755
-
Co-Delivery of Doxorubicin and Paclitaxel by PEG-Polypeptide Nanovehicle for the Treatment of Non-Small Cell Lung Cancer
-
Lv, S.; Tang, Z.; Li, M.; Lin, J.; Song, W.; Liu, H.; Huang, Y.; Zhang, Y.; Chen, X. Co-Delivery of Doxorubicin and Paclitaxel by PEG-Polypeptide Nanovehicle for the Treatment of Non-Small Cell Lung Cancer Biomaterials 2014, 35, 6118-6129
-
(2014)
Biomaterials
, vol.35
, pp. 6118-6129
-
-
Lv, S.1
Tang, Z.2
Li, M.3
Lin, J.4
Song, W.5
Liu, H.6
Huang, Y.7
Zhang, Y.8
Chen, X.9
-
53
-
-
0013228058
-
Doxorubicin Cardiotoxicity May be Caused by Its Metabolite, Doxorubicinol
-
Olson, R. D.; Mushlin, P. S.; Brenner, D. E.; Fleischer, S.; Cusack, B. J.; Chang, B. K.; Boucek, R. J., Jr. Doxorubicin Cardiotoxicity May be Caused by Its Metabolite, Doxorubicinol Proc. Natl. Acad. Sci. U. S. A. 1988, 85, 3585-3589
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 3585-3589
-
-
Olson, R.D.1
Mushlin, P.S.2
Brenner, D.E.3
Fleischer, S.4
Cusack, B.J.5
Chang, B.K.6
Boucek, Jr.R.J.7
-
54
-
-
0025378582
-
Efficacy and Toxicity of 5-Fluorouracil and Folates in Advanced Colon Cancer
-
Cortesi, E.; Aschelter, A. M.; Gioacchini, N.; Pellegrini, A.; Frati, L.; Ficorella, C.; Mazzei, N.; Marchetti, P. Efficacy and Toxicity of 5-Fluorouracil and Folates in Advanced Colon Cancer J. Chemother. 1990, 2, 47-50
-
(1990)
J. Chemother.
, vol.2
, pp. 47-50
-
-
Cortesi, E.1
Aschelter, A.M.2
Gioacchini, N.3
Pellegrini, A.4
Frati, L.5
Ficorella, C.6
Mazzei, N.7
Marchetti, P.8
|