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Volumn 13, Issue 12, 2013, Pages 1648-1660

HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: Physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy

(7) Kostková, Hana a Etrych, Tomáš a Říhová, Blanka b Kostka, Libor a Starovoytová, Larisa a Kovář, Marek b Ulbrich, Karel a

a INSTITUTE OF MACROMOLECULAR CHEMISTRY (Czech Republic)

b INSTITUTE OF MICROBIOLOGY (Czech Republic)

Author keywords

combination therapy; doxorubicin; HPMA copolymers; Mitomycin C; tumor treatment

Indexed keywords

COMBINATION THERAPY; DOXORUBICIN; HPMA COPOLYMERS; MITOMYCIN C; TUMOR TREATMENT;

COVALENT BONDS; CYTOTOXICITY; DISEASES; T-CELLS; TUMORS;

COPOLYMERS;

DOXORUBICIN; HIGH MOLECULAR WEIGHT DIBLOCK COPOLYMER; LEVULINIC ACID; LINEAR COPOLYMER; MITOMYCIN; MONOMER; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; UNCLASSIFIED DRUG;

ACYLATION; ANALYTICAL PARAMETERS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; B CELL LYMPHOMA; BIODEGRADATION; BODY WEIGHT; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER TRANSPLANTATION; COMBINATION INDEX ANALYSIS; CONTROLLED STUDY; CYTOSTASIS; CYTOTOXICITY; DISULFIDE BOND; DRUG ANALYSIS; DRUG CONJUGATION; DRUG POTENTIATION; DRUG RELEASE; DRUG SYNTHESIS; HYDRODYNAMICS; IC 50; IN VITRO STUDY; IN VIVO STUDY; INFANT; LEWIS CARCINOMA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OVERALL SURVIVAL; PHYSICAL CHEMISTRY; PRECURSOR; SOLID TUMOR; SURVIVAL TIME; T CELL LYMPHOMA; THERAPY EFFECT; TUMOR GROWTH; TUMOR VOLUME;

COMBINATION THERAPY; DOXORUBICIN; HPMA COPOLYMERS; MITOMYCIN C; TUMOR TREATMENT;

ACRYLAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CYTOTOXINS; DISULFIDES; DOXORUBICIN; DRUG CARRIERS; DRUG THERAPY, COMBINATION; FEMALE; KINETICS; LEVULINIC ACIDS; LYMPHOMA, B-CELL; LYMPHOMA, T-CELL; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED C57BL; MITOMYCIN; NEOPLASM TRANSPLANTATION; SURVIVAL ANALYSIS; TUMOR BURDEN;

EID: 84890560256 PISSN: 16165187 EISSN: 16165195 Source Type: Journal
DOI: 10.1002/mabi.201300288 Document Type: Article

Times cited : (30)

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