Hydrazone-bearing PMMA-functionalized magnetic nanocubes as pH-responsive drug carriers for remotely targeted cancer therapy in vitro and in vivo

ACS Applied Materials and Interfaces

Volumn 6, Issue 10, 2014, Pages 7395-7407

  Ding, Xingwei ^a   Liu, Yun ^a   Li, Jinghua ^a   Luo, Zhong ^a   Hu, Yan ^a   Zhang, Beilu ^a   Liu, Junjie ^a   Zhou, Jun ^a   Cai, Kaiyong ^a  

^a CHONGQING UNIVERSITY   (China)

Author keywords

cancer therapy; cytotoxicity; in vivo; magnetic nanocubes; pH responsive drug delivery

Indexed keywords

ASSAYS; AUTOMOBILE MANUFACTURE; CELL DEATH; CYTOTOXICITY; DRUG DELIVERY; ESTERS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; MAGNETIC MATERIALS; MAGNETIC RESONANCE IMAGING; MAGNETISM; MOLECULAR BIOLOGY; ONCOLOGY; THERMOGRAVIMETRIC ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

CANCER THERAPY; CONFOCAL LASER SCANNING MICROSCOPY; EXTERNAL MAGNETIC FIELD; IN-VIVO; NANOCUBES; PH-RESPONSIVE; POLY(METHYL METHACRYLATE) (PMMA); TARGETED CANCER THERAPY;

LOADING;

ANTINEOPLASTIC ANTIBIOTIC; BIOMATERIAL; DOXORUBICIN; DRUG CARRIER; FLUORESCEIN ISOTHIOCYANATE; HYDRAZONE DERIVATIVE; MAGNETITE NANOPARTICLE; POLY(METHYL METHACRYLATE);

ANIMAL; APOPTOSIS; CHEMISTRY; DRUG EFFECTS; ENDOCYTOSIS; FEMALE; HELA CELL LINE; HUMAN; MOUSE; NEOPLASMS; NUCLEAR MAGNETIC RESONANCE IMAGING; NUDE MOUSE; PATHOLOGY; PH; XENOGRAFT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BIOCOMPATIBLE MATERIALS; DOXORUBICIN; DRUG CARRIERS; ENDOCYTOSIS; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; HELA CELLS; HUMANS; HYDRAZONES; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICE; MICE, NUDE; NEOPLASMS; POLYMETHYL METHACRYLATE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84901649927     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am500818m     Document Type: Article

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