Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10

PLoS Genetics

Volumn 11, Issue 3, 2015, Pages

  Bergeron, Karl F ^a   Cardinal, Tatiana ^a   Touré, Aboubacrine M ^a   Béland, Mélanie ^a,c   Raiwet, Diana L ^b   Silversides, David W ^b   Pilon, Nicolas ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EDN3 PROTEIN; EDNRB PROTEIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; PROTEIN RET; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; FAM162B PROTEIN, MOUSE; NERVE PROTEIN; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHROMOSOME 10; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FAM162B GENE; FEMALE; GENDER BIAS; GENE DESERT; GENE INSERTION; GENE LOCATION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC CONSERVATION; HETEROZYGOSITY; HIRSCHSPRUNG DISEASE; HOMOZYGOSITY; INTESTINE; INTESTINE INNERVATION; MALE; MOUSE; MOUSE STRAIN; NEURAL CREST CELL; NONHUMAN; PHENOTYPE; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; SEQUENCE ANALYSIS; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SILENCER ELEMENT; TASHT MOUSE; TRANSACTIVATION ASSAY; TRANSCRIPTION REGULATION; TRANSGENICS; UPREGULATION; X CHROMOSOME; X CHROMOSOME LINKAGE; Y CHROMOSOME; ABNORMALITIES; ANIMAL; CHROMOSOME; DISEASE MODEL; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEURAL CREST; PATHOLOGY;

ANIMALIA; MUS;

ANIMALS; CHROMOSOMES, MAMMALIAN; DISEASE MODELS, ANIMAL; ENTERIC NERVOUS SYSTEM; HIRSCHSPRUNG DISEASE; MALE; MICE; MUTAGENESIS, INSERTIONAL; NERVE TISSUE PROTEINS; NEURAL CREST; SILENCER ELEMENTS, TRANSCRIPTIONAL; TRANSCRIPTOME;

EID: 84926321738     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005093     Document Type: Article

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