-
2
-
-
2342621476
-
Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle
-
Straczkowski M, Kowalska I, Nikolajuk A, Dzienis-Straczkowska S, Kinalska I, Baranowski M, Zendzian-Piotrowska M, Brzezinska Z, Gorski J: Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle. Diabetes 2004;53:1215-1221.
-
(2004)
Diabetes
, vol.53
, pp. 1215-1221
-
-
Straczkowski, M.1
Kowalska, I.2
Nikolajuk, A.3
Dzienis-Straczkowska, S.4
Kinalska, I.5
Baranowski, M.6
Zendzian-Piotrowska, M.7
Brzezinska, Z.8
Gorski, J.9
-
3
-
-
84862270029
-
Ectopic fat and insulin resistance: Pathophysiology and effect of diet and lifestyle interventions
-
Snel M, Jonker JT, Schoones J, Lamb H, de Roos A, Pijl H, Smit JW, Meinders AE, Jazet IM: Ectopic fat and insulin resistance: Pathophysiology and effect of diet and lifestyle interventions. Int J Endocrinol 2012;2012:983814.
-
(2012)
Int J Endocrinol
, vol.2012
, pp. 983814
-
-
Snel, M.1
Jonker, J.T.2
Schoones, J.3
Lamb, H.4
De Roos, A.5
Pijl, H.6
Smit, J.W.7
Meinders, A.E.8
Jazet, I.M.9
-
4
-
-
57649195613
-
Dietary fats and prevention of type 2 diabetes
-
Riserus U, Willett WC, Hu FB: Dietary fats and prevention of type 2 diabetes. Prog Lipid Res 2009;48:44-51.
-
(2009)
Prog Lipid Res
, vol.48
, pp. 44-51
-
-
Riserus, U.1
Willett, W.C.2
Hu, F.B.3
-
5
-
-
84901944641
-
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
-
Perry RJ, Samuel VT, Petersen KF, Shulman GI: The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature 2014;510:84-91.
-
(2014)
Nature
, vol.510
, pp. 84-91
-
-
Perry, R.J.1
Samuel, V.T.2
Petersen, K.F.3
Shulman, G.I.4
-
6
-
-
75549085755
-
Skeletal muscle insulin resistance is the primary defect in type 2 diabetes
-
DeFronzo RA, Tripathy D: Skeletal muscle insulin resistance is the primary defect in type 2 diabetes. Diabetes Care 2009;32:S157-163.
-
(2009)
Diabetes Care
, vol.32
, pp. S157-163
-
-
Defronzo, R.A.1
Tripathy, D.2
-
7
-
-
84893438162
-
Effects of inhibition of serine palmitoyltransferase (spt) and sphingosine kinase 1 (sphk1) on palmitate induced insulin resistance in l6 myotubes
-
Miklosz A, Lukaszuk B, Baranowski M, Gorski J, Chabowski A: Effects of inhibition of serine palmitoyltransferase (spt) and sphingosine kinase 1 (sphk1) on palmitate induced insulin resistance in l6 myotubes. PLoS One 2013;8:e85547.
-
(2013)
PLoS One
, vol.8
, pp. e85547
-
-
Miklosz, A.1
Lukaszuk, B.2
Baranowski, M.3
Gorski, J.4
Chabowski, A.5
-
8
-
-
33644846005
-
Skeletal muscle lipid metabolism in exercise and insulin resistance
-
Kiens B: Skeletal muscle lipid metabolism in exercise and insulin resistance. Physiol Rev 2006;86:205-243.
-
(2006)
Physiol Rev
, vol.86
, pp. 205-243
-
-
Kiens, B.1
-
9
-
-
42949084209
-
Muscular diacylglycerol metabolism and insulin resistance
-
Timmers S, Schrauwen P, de Vogel J: Muscular diacylglycerol metabolism and insulin resistance. Physiol Behav 2008;94:242-251.
-
(2008)
Physiol Behav
, vol.94
, pp. 242-251
-
-
Timmers, S.1
Schrauwen, P.2
De Vogel, J.3
-
10
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
Summers SA: Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 2006;45:42-72.
-
(2006)
Prog Lipid Res
, vol.45
, pp. 42-72
-
-
Summers, S.A.1
-
11
-
-
56049107038
-
Pgc-1 coactivators and skeletal muscle adaptations in health and disease
-
Arany Z: Pgc-1 coactivators and skeletal muscle adaptations in health and disease. Curr Opin Genet Dev 2008;18:426-434.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 426-434
-
-
Arany, Z.1
-
12
-
-
24144463983
-
Metabolic control through the pgc-1 family of transcription coactivators
-
Lin J, Handschin C, Spiegelman BM: Metabolic control through the pgc-1 family of transcription coactivators. Cell Metab 2005;1:361-370.
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
13
-
-
33644660537
-
Pgc-1 coactivators: Inducible regulators of energy metabolism in health and disease
-
Finck BN, Kelly DP: Pgc-1 coactivators: Inducible regulators of energy metabolism in health and disease. J Clin Invest 2006;116:615-622.
-
(2006)
J Clin Invest
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
14
-
-
33846992686
-
Exercise-induced mitochondrial biogenesis begins before the increase in muscle pgc-1alpha expression
-
Wright DC, Han DH, Garcia-Roves PM, Geiger PC, Jones TE, Holloszy JO: Exercise-induced mitochondrial biogenesis begins before the increase in muscle pgc-1alpha expression. J Biol Chem 2007;282:194-199.
-
(2007)
J Biol Chem
, vol.282
, pp. 194-199
-
-
Wright, D.C.1
Han, D.H.2
Garcia-Roves, P.M.3
Geiger, P.C.4
Jones, T.E.5
Holloszy, J.O.6
-
15
-
-
77958453583
-
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (pgc-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway
-
Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C: Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (pgc-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway. J Biol Chem 2010;285:32793-32800.
-
(2010)
J Biol Chem
, vol.285
, pp. 32793-32800
-
-
Summermatter, S.1
Baum, O.2
Santos, G.3
Hoppeler, H.4
Handschin, C.5
-
16
-
-
77956802137
-
Pgc-1{alpha} is required for aicar-induced expression of glut4 and mitochondrial proteins in mouse skeletal muscle
-
Leick L, Fentz J, Bienso RS, Knudsen JG, Jeppesen J, Kiens B, Wojtaszewski JF, Pilegaard H: Pgc-1{alpha} is required for aicar-induced expression of glut4 and mitochondrial proteins in mouse skeletal muscle. Am J Physiol Endocrinol Metab 2010;299:E456-465.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, pp. E456-465
-
-
Leick, L.1
Fentz, J.2
Bienso, R.S.3
Knudsen, J.G.4
Jeppesen, J.5
Kiens, B.6
Wojtaszewski, J.F.7
Pilegaard, H.8
-
17
-
-
53649107138
-
Pgc-1alpha-mediated regulation of gene expression and metabolism: Implications for nutrition and exercise prescriptions
-
Benton CR, Wright DC, Bonen A: Pgc-1alpha-mediated regulation of gene expression and metabolism: Implications for nutrition and exercise prescriptions. Appl Physiol Nutr Metab 2008;33:843-862.
-
(2008)
Appl Physiol Nutr Metab
, vol.33
, pp. 843-862
-
-
Benton, C.R.1
Wright, D.C.2
Bonen, A.3
-
18
-
-
34447533581
-
Is membrane transport of ffa mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: Molecular, biochemical, and physiological evidence
-
Bonen A, Chabowski A, Luiken JJ, Glatz JF: Is membrane transport of ffa mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: Molecular, biochemical, and physiological evidence. Physiology (Bethesda) 2007;22:15-29.
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 15-29
-
-
Bonen, A.1
Chabowski, A.2
Luiken, J.J.3
Glatz, J.F.4
-
19
-
-
79959379975
-
Effects of 3t3 adipocytes on interleukin-6 expression and insulin signaling in l6 skeletal muscle cells
-
Seyoum B, Fite A, Abou-Samra AB: Effects of 3t3 adipocytes on interleukin-6 expression and insulin signaling in l6 skeletal muscle cells. Biochem Biophys Res Commun 2011;410:13-18.
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 13-18
-
-
Seyoum, B.1
Fite, A.2
Abou-Samra, A.B.3
-
20
-
-
84872687809
-
Genetic downregulation of receptor-interacting protein 140 uncovers the central role of akt signalling in the regulation of fatty acid oxidation in skeletal muscle cells
-
Constantinescu S, Turcotte LP: Genetic downregulation of receptor-interacting protein 140 uncovers the central role of akt signalling in the regulation of fatty acid oxidation in skeletal muscle cells. Exp Physiol 2013;98:514-525.
-
(2013)
Exp Physiol
, vol.98
, pp. 514-525
-
-
Constantinescu, S.1
Turcotte, L.P.2
-
21
-
-
84867797128
-
Effects of hyperthyroidism on lipid content and composition in oxidative and glycolytic muscles in rats
-
Miklosz A, Chabowski A, Zendzian-Piotrowska M, Gorski J: Effects of hyperthyroidism on lipid content and composition in oxidative and glycolytic muscles in rats. J Physiol Pharmacol 2012;63:403-410.
-
(2012)
J Physiol Pharmacol
, vol.63
, pp. 403-410
-
-
Miklosz, A.1
Chabowski, A.2
Zendzian-Piotrowska, M.3
Gorski, J.4
-
22
-
-
0142164965
-
Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3t3-l1 adipocytes and c2c12 myotubes
-
Chavez JA, Summers SA: Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3t3-l1 adipocytes and c2c12 myotubes. Arch Biochem Biophys 2003;419:101-109.
-
(2003)
Arch Biochem Biophys
, vol.419
, pp. 101-109
-
-
Chavez, J.A.1
Summers, S.A.2
-
23
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-917.
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
24
-
-
0031716302
-
Quantitative analysis of ceramide molecular species by high performance liquid chromatography
-
Yano M, Kishida E, Muneyuki Y, Masuzawa Y: Quantitative analysis of ceramide molecular species by high performance liquid chromatography. J Lipid Res 1998;39:2091-2098.
-
(1998)
J Lipid Res
, vol.39
, pp. 2091-2098
-
-
Yano, M.1
Kishida, E.2
Muneyuki, Y.3
Masuzawa, Y.4
-
25
-
-
29944445284
-
Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state
-
van Loon LJ, Goodpaster BH: Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state. Pflugers Arch 2006;451:606-616.
-
(2006)
Pflugers Arch
, vol.451
, pp. 606-616
-
-
Van Loon, L.J.1
Goodpaster, B.H.2
-
26
-
-
77951633406
-
Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and-1beta in cultured myotubes
-
Espinoza DO, Boros LG, Crunkhorn S, Gami H, Patti ME: Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and-1beta in cultured myotubes. Faseb j 2010;24:1003-1014.
-
(2010)
Faseb J
, vol.24
, pp. 1003-1014
-
-
Espinoza, D.O.1
Boros, L.G.2
Crunkhorn, S.3
Gami, H.4
Patti, M.E.5
-
27
-
-
73649100201
-
Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity
-
Ritov VB, Menshikova EV, Azuma K, Wood R, Toledo FG, Goodpaster BH, Ruderman NB, Kelley DE: Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity. Am J Physiol Endocrinol Metab 2010;298:E49-58.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, pp. E49-58
-
-
Ritov, V.B.1
Menshikova, E.V.2
Azuma, K.3
Wood, R.4
Toledo, F.G.5
Goodpaster, B.H.6
Ruderman, N.B.7
De, K.8
-
28
-
-
0032792665
-
Amp-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes
-
Winder WW, Hardie DG: Amp-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes. Am J Physiol 1999;277:E1-10.
-
(1999)
Am J Physiol
, vol.277
, pp. E1-10
-
-
Winder, W.W.1
Hardie, D.G.2
-
29
-
-
65649148341
-
Whole body overexpression of pgc-1alpha has opposite effects on hepatic and muscle insulin sensitivity
-
Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O'Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF: Whole body overexpression of pgc-1alpha has opposite effects on hepatic and muscle insulin sensitivity. Am J Physiol Endocrinol Metab 2009;296:E945-954.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, pp. E945-954
-
-
Liang, H.1
Balas, B.2
Tantiwong, P.3
Dube, J.4
Goodpaster, B.H.5
O'Doherty, R.M.6
Defronzo, R.A.7
Richardson, A.8
Musi, N.9
Ward, W.F.10
-
30
-
-
84872050740
-
Pgc-1alpha improves glucose homeostasis in skeletal muscle in an activity-dependent manner
-
Summermatter S, Shui G, Maag D, Santos G, Wenk MR, Handschin C: Pgc-1alpha improves glucose homeostasis in skeletal muscle in an activity-dependent manner. Diabetes 2013;62:85-95.
-
(2013)
Diabetes
, vol.62
, pp. 85-95
-
-
Summermatter, S.1
Shui, G.2
Maag, D.3
Santos, G.4
Wenk, M.R.5
Handschin, C.6
-
31
-
-
29244436681
-
Ampk activation increases fatty acid oxidation in skeletal muscle by activating pparalpha and pgc-1
-
Lee WJ, Kim M, Park HS, Kim HS, Jeon MJ, Oh KS, Koh EH, Won JC, Kim MS, Oh GT, Yoon M, Lee KU, Park JY: Ampk activation increases fatty acid oxidation in skeletal muscle by activating pparalpha and pgc-1. Biochem Biophys Res Commun 2006;340:291-295.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 291-295
-
-
Lee, W.J.1
Kim, M.2
Park, H.S.3
Kim, H.S.4
Jeon, M.J.5
Oh, K.S.6
Koh, E.H.7
Won, J.C.8
Kim, M.S.9
Oh, G.T.10
Yoon, M.11
Lee, K.U.12
Park, J.Y.13
-
32
-
-
77955560424
-
Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (pgc-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese zucker rats
-
Benton CR, Holloway GP, Han XX, Yoshida Y, Snook LA, Lally J, Glatz JF, Luiken JJ, Chabowski A, Bonen A: Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (pgc-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese zucker rats. Diabetologia 2010;53:2008-2019.
-
(2010)
Diabetologia
, vol.53
, pp. 2008-2019
-
-
Benton, C.R.1
Holloway, G.P.2
Han, X.X.3
Yoshida, Y.4
Snook, L.A.5
Lally, J.6
Glatz, J.F.7
Luiken, J.J.8
Chabowski, A.9
Bonen, A.10
|