Interleukin-1 beta increases activity of human endothelial progenitor cells: Involvement of PI3K-AKT signaling pathway

Inflammation

Volumn 35, Issue 4, 2012, Pages 1242-1250

  Yang, Lin ^a   Guo, Xiao Gang ^a   Du, Chang Qing ^b   Yang, Jin Xiu ^a   Jiang, Dong Mei ^c   Li, Bo ^d   Zhou, Wen Jing ^a   Zhang, Fu Rong ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG HOSPITAL   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Akt; Endothelial progenitor cells; Interleukin 1beta; VEGF A

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; INTERLEUKIN 1BETA; LIPOCORTIN 5; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIDIUM IODIDE; PROTEIN KINASE B; TETRAZOLIUM; VASCULOTROPIN A;

ADULT; APOPTOSIS; ARTICLE; BINDING ASSAY; CELL ACTIVITY; CELL ADHESION; CELL ASSAY; CELL CULTURE; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIAL PROGENITOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

APOPTOSIS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHROMONES; ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-1BETA; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEM CELLS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84866735888     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-012-9434-9     Document Type: Article

References (24)

1. Asahara, T., T. Murohara, A. Sullivan, M. Silver, R. van der Zee, T. Li, et al. 1997. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964-967.
2. Hristov, M., W. Erl, and P.C. Weber. 2003. Endothelial progenitor cells: Mobilization, differentiation, and homing. Arteriosclerosis, Thrombosis, and Vascular Biology 23: 1185-1189.
3. Amano, K., M. Okigaki, Y. Adachi, S. Fujiyama, Y. Mori, A. Kosaki, et al. 2004. Mechanism for IL-1 beta-mediated neovascularization unmasked by IL-1 beta knock-out mice. Journal of Molecular and Cellular Cardiology 36(4): 469-480.
4. Werner, N., and G. Nickenig. 2006. Influence of cardiovascular risk factors on endothelial progenitor cells: Limitations for therapy? Arteriosclerosis, Thrombosis, and Vascular Biology 26: 257-266.
5. Urbich, C., A. Aicher, C. Heeschen, E. Dernbach, W.K. Hofmann, A.M. Zeiher, et al. 2005. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. Journal of Molecular and Cellular Cardiology 39: 733-742.
6. Yamazaki, Y., and T. Morita. 2006. Molecular and functional diversity of vascular endothelial growth factors. Molecular Diversity 10: 515-527.
7. Jia, H., A. Bagherzadeh, R. Bicknell, M.R. Duchen, D. Liu, and I. Zachary. 2004. Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells. Journal of Biological Chemistry 279: 36148-36157.
8. Dimmeler, S., A. Aicher, M. Vasa, C. Mildner-Rihm, K. Adler, M. Tiemann, et al. 2001. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. The Journal of Clinical Investigation 108: 391-397.
9. Qiu, F.Y., X.X. Song, H. Zheng, Y.B. Zhao, and G.S. Fu. 2009. Thymosin beta4 induces endothelial progenitor cell migration via PI3K/Akt/eNOS signal transduction pathway. Journal of Cardiovascular Pharmacology 53(3): 209-214.
10. Wada, T., and J.M. Penninger. 2004. Mitogen-Activated protein kinases in apoptosis regulation. Oncogene 23: 2838-2849.
11. Ono, K., A. Matsumori, T. Shioi, Y. Furukawa, and S. Sasayama. 1998. Cytokine gene expression after myocardial infarction in rat hearts: Possible implication in left ventricular remodeling. Circulation 98: 149-156.
12. Pudil, R., V. Pidrman, J.Krejsek, J.Gregor,M. Tichý, C.Andrýs, et al. 1999. Cytokines and adhesion molecules in the course of acute myocardial infarction. Clinica Chimica Acta 280(1-2): 127-134.
13. Henrich, D., C. Seebach, K. Wilhelm, and I. Marzi. 2007. High dosage of simvastatin reduces TNF-Alpha-induced apoptosis of endothelial progenitor cells but fails to prevent apoptosis induced by IL-1beta in vitro. Journal of Surgical Research 142: 13-19.
14. Rosell, A., K. Arai, J. Lok, T. He, S. Guo, M. Navarro, et al. 2009. Interleukin-1beta augments angiogenic responses of murine endothelial progenitor cells in vitro. Journal of Cerebral Blood Flow and Metabolism 29: 933-943.
15. Chen, J.Z., J.H. Zhu, X.X. Wang, J.H. Zhu, X.D. Xie, J. Sun, et al. 2004. Effects of homocysteine on number and activity of endothelial progenitor cells from peripheral blood. Journal of Molecular and Cellular Cardiology 36: 233-239.
16. Wang, X.X., F.R. Zhang, Y.P. Shang, J.H. Zhu, X.D. Xie, Q.M. Tao, et al. 2007. Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: A pilot randomized controlled trial. Journal of the American College of Cardiology 49(14): 1566-1571.
17. Hu, X.S., C.Q. Du, L. Yang, X.Y. Yao, and S.J. Hu. 2010. Proteasome inhibitor MG132 suppresses number and function of endothelial progenitor cells: Involvement of nitric oxide synthase inhibition. International Journal of Molecular Medicine 25(3): 385-392.
18. Xia, L., X.X. Wang, X.S. Hu, X.G. Guo, Y.P. Shang, H.J. Chen, et al. 2008. Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Aktdependent mechanisms. British Journal of Pharmacology 155: 387-394.
19. Yang, Z., J.M. Wang, L. Chen, C.F. Luo, A.L. Tang, and J. Tao. 2007. Acute exercise-induced nitric oxide production contributes to upregulation of circulating endothelial progenitor cells in healthy subjects. Journal of Human Hypertension 21: 452-460.
20. Qin, S.L., T.S. Li, M. Takahashi, and K. Hamano. 2006. In vitro assessment of the effect of interleukin-1beta on angiogenic potential of bone marrow cells. Circulation Journal 70: 1195-1199.
21. Fan, F., O. Stoeltzing, W. Liu, M.F. McCarty, Y.D. Jung, N. Reinmuth, et al. 2004. Interleukin-1beta regulates angiopoietin-1 expression in human endothelial cells. Cancer Research 64: 3186-3190.
22. Asahara, T., T. Takahashi, H. Masuda, C. Kalka, D. Chen, H. Iwaguro, et al. 1999. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO Journal 18: 3964-3972.
23. Fadini, G.P., I. Baesso, M. Albiero, S. Sartore, C. Agostini, and A. Avogaro. 2008. Technical notes on endothelial progenitor cells: Ways to escape from the knowledge plateau. Atherosclerosis 197: 496-503.
24. Richardson, M.R., and M.C. Yoder. 2011. Endothelial progenitor cells: Quo Vadis? Journal of Molecular and Cellular Cardiology 50(2): 266-272.