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Volumn 30, Issue 10, 2014, Pages 1185-1194

Glutamine suppresses Hsp72 not Hsp90α and is not inducing Th1, Th2, or Th17 cytokine responses in human septic PBMCs

Author keywords

Cytokines; Glutamine; Heat shock protein 72; Heat shock protein 90 ; Lipopolysaccharide; Peripheral blood mononuclear cells; Severe sepsis

Indexed keywords

ALANINE; GAMMA INTERFERON; GLUTAMINE; HEAT SHOCK PROTEIN 72; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 ALPHA; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; UNCLASSIFIED DRUG; ALANYLGLUTAMINE; CYTOKINE; DIPEPTIDE; HEAT SHOCK PROTEIN;

EID: 84926256784     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2014.01.018     Document Type: Article
Times cited : (15)

References (42)
  • 1
    • 84898132858 scopus 로고    scopus 로고
    • Do reciprocal interactions between cell stress proteins and cytokines create a new intra-/extra-cellular signalling nexus?
    • Henderson B., Kaiser F. Do reciprocal interactions between cell stress proteins and cytokines create a new intra-/extra-cellular signalling nexus?. Cell Stress Chaperones 2013, 18:685-701.
    • (2013) Cell Stress Chaperones , vol.18 , pp. 685-701
    • Henderson, B.1    Kaiser, F.2
  • 2
    • 0036327153 scopus 로고    scopus 로고
    • Whole-body hyperthermia-induced thermotolerance is associated with the induction of heat shock protein 70 in mice
    • King Y.T., Lin C.S., Lin J.H., Lee W.C. Whole-body hyperthermia-induced thermotolerance is associated with the induction of heat shock protein 70 in mice. J Exp Biol 2002, 205(Pt 2):273-278.
    • (2002) J Exp Biol , vol.205 , pp. 273-278
    • King, Y.T.1    Lin, C.S.2    Lin, J.H.3    Lee, W.C.4
  • 3
    • 33747341005 scopus 로고    scopus 로고
    • The inhibition of LPS-induced production of inflammatory cytokines by Hsp70 involves inactivation of the NF-kappaB pathway but not the MAPK pathways
    • Shi Y., Tu Z., Tang D., Zhang H., Liu M., Wang K., et al. The inhibition of LPS-induced production of inflammatory cytokines by Hsp70 involves inactivation of the NF-kappaB pathway but not the MAPK pathways. Shock 2006, 26:277-284.
    • (2006) Shock , vol.26 , pp. 277-284
    • Shi, Y.1    Tu, Z.2    Tang, D.3    Zhang, H.4    Liu, M.5    Wang, K.6
  • 4
    • 0036084783 scopus 로고    scopus 로고
    • Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance
    • Kregel K.C. Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J Appl Physiol 2002, 92:2177-2186.
    • (2002) J Appl Physiol , vol.92 , pp. 2177-2186
    • Kregel, K.C.1
  • 6
    • 0035203050 scopus 로고    scopus 로고
    • Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages
    • Kim S.O., Ono K., Han J. Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages. Am J Physiol Lung Cell Mol Physiol 2001, 281:L1095-L1105.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281 , pp. L1095-L1105
    • Kim, S.O.1    Ono, K.2    Han, J.3
  • 7
    • 0037151057 scopus 로고    scopus 로고
    • Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression
    • Hsu H.Y., Wen M.H. Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression. J Biol Chem 2002, 277:22131-22139.
    • (2002) J Biol Chem , vol.277 , pp. 22131-22139
    • Hsu, H.Y.1    Wen, M.H.2
  • 8
    • 33845876330 scopus 로고    scopus 로고
    • Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages
    • Hsu H.Y., Wu H.L., Tan S.K., Li V.P., Wang W.T., Hsu J., et al. Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages. Mol Pharmacol 2007, 71:344-356.
    • (2007) Mol Pharmacol , vol.71 , pp. 344-356
    • Hsu, H.Y.1    Wu, H.L.2    Tan, S.K.3    Li, V.P.4    Wang, W.T.5    Hsu, J.6
  • 9
    • 0032192268 scopus 로고    scopus 로고
    • Cytokine production by human peripheral blood mononuclear cells: Differential sensitivity to glutamine availability
    • Yaqoob P., Calder P.C. Cytokine production by human peripheral blood mononuclear cells: Differential sensitivity to glutamine availability. Cytokine 1998, 10:790-794.
    • (1998) Cytokine , vol.10 , pp. 790-794
    • Yaqoob, P.1    Calder, P.C.2
  • 10
    • 0032804665 scopus 로고    scopus 로고
    • Effect of glutamine on Th1 and Th2 cytokine responses of human peripheral blood mononuclear cells
    • Chang W.K., Yang K.D., Shaio M.F. Effect of glutamine on Th1 and Th2 cytokine responses of human peripheral blood mononuclear cells. Clin Immunol 1999, 93:294-301.
    • (1999) Clin Immunol , vol.93 , pp. 294-301
    • Chang, W.K.1    Yang, K.D.2    Shaio, M.F.3
  • 11
    • 0037221363 scopus 로고    scopus 로고
    • Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells
    • Wischmeyer P.E., Riehm J., Singleton K.D., Ren H., Musch M.W., Kahana M., et al. Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells. Nutrition 2003, 19:1-6.
    • (2003) Nutrition , vol.19 , pp. 1-6
    • Wischmeyer, P.E.1    Riehm, J.2    Singleton, K.D.3    Ren, H.4    Musch, M.W.5    Kahana, M.6
  • 12
    • 0035000171 scopus 로고    scopus 로고
    • Glutamine induces heat shock protein and protects against endotoxin shock in the rat
    • Wischmeyer P.E., Kahana M., Wolfson R., Ren H., Musch M.M., Chang E.B. Glutamine induces heat shock protein and protects against endotoxin shock in the rat. J Appl Physiol 2001, 90:2403-2410.
    • (2001) J Appl Physiol , vol.90 , pp. 2403-2410
    • Wischmeyer, P.E.1    Kahana, M.2    Wolfson, R.3    Ren, H.4    Musch, M.M.5    Chang, E.B.6
  • 13
    • 0034657795 scopus 로고    scopus 로고
    • Anti-inflammatory effect of heat shock protein induction is related to stabilization of I kappa B alpha through preventing I kappa B kinase activation in respiratory epithelial cells
    • Yoo C.G., Lee S., Lee C.T., Kim Y.W., Han S.K., Shim Y.S. Anti-inflammatory effect of heat shock protein induction is related to stabilization of I kappa B alpha through preventing I kappa B kinase activation in respiratory epithelial cells. J Immunol 2000, 164:5416-5423.
    • (2000) J Immunol , vol.164 , pp. 5416-5423
    • Yoo, C.G.1    Lee, S.2    Lee, C.T.3    Kim, Y.W.4    Han, S.K.5    Shim, Y.S.6
  • 14
    • 0032998431 scopus 로고    scopus 로고
    • Why immunomodulatory therapies have not worked in sepsis?
    • Abraham E. Why immunomodulatory therapies have not worked in sepsis?. Intensive Care Med 1999, 25:556-566.
    • (1999) Intensive Care Med , vol.25 , pp. 556-566
    • Abraham, E.1
  • 15
    • 84876336998 scopus 로고    scopus 로고
    • A randomized trial of glutamine and antioxidants in critically ill patients
    • Canadian Critical Care Trials Group
    • Heyland D., Muscedere J., Wischmeyer P.E., Cook D., Jones G., Albert M., et al. A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med 2013, 368:1489-1497. Canadian Critical Care Trials Group.
    • (2013) N Engl J Med , vol.368 , pp. 1489-1497
    • Heyland, D.1    Muscedere, J.2    Wischmeyer, P.E.3    Cook, D.4    Jones, G.5    Albert, M.6
  • 16
    • 84858293825 scopus 로고    scopus 로고
    • The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN)
    • Carcillo J.A., Dean J.M., Holubkov R., Berger J., Meert K.L., Anand K.J., et al. The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. Pediatr Crit Care Med 2012, 13:165-173. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN).
    • (2012) Pediatr Crit Care Med , vol.13 , pp. 165-173
    • Carcillo, J.A.1    Dean, J.M.2    Holubkov, R.3    Berger, J.4    Meert, K.L.5    Anand, K.J.6
  • 17
    • 77955895056 scopus 로고    scopus 로고
    • Invitro heat shock of human monocytes results in a proportional increase of inducible Hsp70 expression according to the basal content
    • Vince R.V., Oliver K., Midgley A.W., McNaughton L.R., Madden L.A. Invitro heat shock of human monocytes results in a proportional increase of inducible Hsp70 expression according to the basal content. Amino Acids 2010, 38:1423-1428.
    • (2010) Amino Acids , vol.38 , pp. 1423-1428
    • Vince, R.V.1    Oliver, K.2    Midgley, A.W.3    McNaughton, L.R.4    Madden, L.A.5
  • 18
    • 33646788790 scopus 로고    scopus 로고
    • Glutamine prevents activation of NF-kappa B and stress kinase pathways, attenuates inflammatory cytokine release, and prevents acute respiratory distress syndrome (ARDS) following sepsis
    • Singleton K.D., Beckey V.E., Wischmeyer P.E. Glutamine prevents activation of NF-kappa B and stress kinase pathways, attenuates inflammatory cytokine release, and prevents acute respiratory distress syndrome (ARDS) following sepsis. Shock 2005, 24:583-589.
    • (2005) Shock , vol.24 , pp. 583-589
    • Singleton, K.D.1    Beckey, V.E.2    Wischmeyer, P.E.3
  • 19
    • 0041828687 scopus 로고    scopus 로고
    • Modulating effect of glutamine on IL-1 beta-induced cytokine production by human gut
    • Coëffier M., Marion R., Ducrotté P., Déchelotte P. Modulating effect of glutamine on IL-1 beta-induced cytokine production by human gut. Clin Nutr 2003, 22:407-413.
    • (2003) Clin Nutr , vol.22 , pp. 407-413
    • Coëffier, M.1    Marion, R.2    Ducrotté, P.3    Déchelotte, P.4
  • 20
    • 84873339299 scopus 로고    scopus 로고
    • Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012
    • Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup
    • Dellinger R.P., Levy M.M., Rhodes A., Annane D., Gerlach H., Opal S.M., et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 2013, 41:580-637. Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup.
    • (2013) Crit Care Med , vol.41 , pp. 580-637
    • Dellinger, R.P.1    Levy, M.M.2    Rhodes, A.3    Annane, D.4    Gerlach, H.5    Opal, S.M.6
  • 21
    • 36549058329 scopus 로고    scopus 로고
    • Translational inhibition of colonic epithelial heat shock proteins by IFN-gamma and TNF-alpha in intestinal inflammation
    • Hu S., Ciancio M.J., Lahav M., Fujiya M., Lichtenstein L., Anant S., et al. Translational inhibition of colonic epithelial heat shock proteins by IFN-gamma and TNF-alpha in intestinal inflammation. Gastroenterology 2007, 133:1893-1904.
    • (2007) Gastroenterology , vol.133 , pp. 1893-1904
    • Hu, S.1    Ciancio, M.J.2    Lahav, M.3    Fujiya, M.4    Lichtenstein, L.5    Anant, S.6
  • 22
    • 39549096469 scopus 로고    scopus 로고
    • Glutamine induces heat-shock protein and protects against Escherichia coli lipopolysaccharide-induced vascular hyporeactivity in rats
    • Jing L., Wu Q., Wang F. Glutamine induces heat-shock protein and protects against Escherichia coli lipopolysaccharide-induced vascular hyporeactivity in rats. Crit Care 2007, 11:R34.
    • (2007) Crit Care , vol.11 , pp. R34
    • Jing, L.1    Wu, Q.2    Wang, F.3
  • 23
    • 84872003344 scopus 로고    scopus 로고
    • The role of glycoprotein 96 in the persistent inflammation of rheumatoid arthritis
    • Huang Q.Q., Pope R.M. The role of glycoprotein 96 in the persistent inflammation of rheumatoid arthritis. Arch Biochem Biophys 2013, 530:1-6.
    • (2013) Arch Biochem Biophys , vol.530 , pp. 1-6
    • Huang, Q.Q.1    Pope, R.M.2
  • 24
    • 80555136832 scopus 로고    scopus 로고
    • A fragment of secreted Hsp90-α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice
    • Cheng C.F., Sahu D., Tsen F., Zhao Z., Fan J., Kim R., et al. A fragment of secreted Hsp90-α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice. J Clin Invest 2011, 121:4348-4361.
    • (2011) J Clin Invest , vol.121 , pp. 4348-4361
    • Cheng, C.F.1    Sahu, D.2    Tsen, F.3    Zhao, Z.4    Fan, J.5    Kim, R.6
  • 25
    • 0032984459 scopus 로고    scopus 로고
    • Endotoxin inhibits heat shock protein 70 (Hsp70) expression in peripheral blood mononuclear cells of patients with severe sepsis
    • Schroeder S., Bischoff J., Lehmann L.E., Hering R., von Spiegel T., Putensen C., et al. Endotoxin inhibits heat shock protein 70 (Hsp70) expression in peripheral blood mononuclear cells of patients with severe sepsis. Intensive Care Med 1999, 25:52-57.
    • (1999) Intensive Care Med , vol.25 , pp. 52-57
    • Schroeder, S.1    Bischoff, J.2    Lehmann, L.E.3    Hering, R.4    von Spiegel, T.5    Putensen, C.6
  • 26
    • 84880909856 scopus 로고    scopus 로고
    • Glutamine and antioxidants in critically ill patients
    • Bistrian B.R. Glutamine and antioxidants in critically ill patients. N Engl J Med 2013, 369:482.
    • (2013) N Engl J Med , vol.369 , pp. 482
    • Bistrian, B.R.1
  • 27
    • 0030738009 scopus 로고    scopus 로고
    • Stimulatory effect of glutamine on human monocyte activation as measured by interleukin-6 and soluble interleukin-6 receptor release
    • Peltonen E., Pulkki K., Kirvelä O. Stimulatory effect of glutamine on human monocyte activation as measured by interleukin-6 and soluble interleukin-6 receptor release. ClinNutr 1997, 16:125-128.
    • (1997) ClinNutr , vol.16 , pp. 125-128
    • Peltonen, E.1    Pulkki, K.2    Kirvelä, O.3
  • 28
    • 0029797129 scopus 로고    scopus 로고
    • Glutamine, lymphocyte proliferation and cytokine production
    • Rohde T., MacLean D.A., Klarlund Pedersen B. Glutamine, lymphocyte proliferation and cytokine production. Scand J Immunol 1996, 44:648-650.
    • (1996) Scand J Immunol , vol.44 , pp. 648-650
    • Rohde, T.1    MacLean, D.A.2    Klarlund Pedersen, B.3
  • 29
    • 79958751355 scopus 로고    scopus 로고
    • The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following invitro stress in human monocytes
    • Vince R.V., Midgley A.W., Laden G., Madden L.A. The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following invitro stress in human monocytes. Cell Stress Chaperones 2011, 16:339-343.
    • (2011) Cell Stress Chaperones , vol.16 , pp. 339-343
    • Vince, R.V.1    Midgley, A.W.2    Laden, G.3    Madden, L.A.4
  • 30
    • 84874509753 scopus 로고    scopus 로고
    • Current trends in inflammatory and immunomodulatory mediators in sepsis
    • Aziz M., Jacob A., Yang W.L., Matsuda A., Wang P. Current trends in inflammatory and immunomodulatory mediators in sepsis. J Leukoc Biol 2013, 93:329-342.
    • (2013) J Leukoc Biol , vol.93 , pp. 329-342
    • Aziz, M.1    Jacob, A.2    Yang, W.L.3    Matsuda, A.4    Wang, P.5
  • 31
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver C.T., Hatton R.D., Mangan P.R., Harrington L.E. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007, 25:821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 32
    • 21244486984 scopus 로고    scopus 로고
    • Comparative effects of early randomized immune or non-immune-enhancing enteral nutrition on cytokine production in children with septic shock
    • Briassoulis G., Filippou O., Kanariou M., Hatzis T. Comparative effects of early randomized immune or non-immune-enhancing enteral nutrition on cytokine production in children with septic shock. Intensive Care Med 2005, 31:851-858.
    • (2005) Intensive Care Med , vol.31 , pp. 851-858
    • Briassoulis, G.1    Filippou, O.2    Kanariou, M.3    Hatzis, T.4
  • 33
    • 84867365243 scopus 로고    scopus 로고
    • Glutamine randomized studies in early life: the unsolved riddle of experimental and clinical studies
    • Briassouli E., Briassoulis G. Glutamine randomized studies in early life: the unsolved riddle of experimental and clinical studies. Clin Dev Immunol 2012, 2012:749189.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 749189
    • Briassouli, E.1    Briassoulis, G.2
  • 35
    • 84891143202 scopus 로고    scopus 로고
    • Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour
    • Kaiser F., Steptoe A., Thompson S., Henderson B. Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour. Cell Stress Chaperones 2014, 19:135-144.
    • (2014) Cell Stress Chaperones , vol.19 , pp. 135-144
    • Kaiser, F.1    Steptoe, A.2    Thompson, S.3    Henderson, B.4
  • 36
    • 0037097758 scopus 로고    scopus 로고
    • Oxidative stress in phagocytes-"the enemy within"
    • Splettstoesser W.D., Schuff-Werner P. Oxidative stress in phagocytes-"the enemy within". Microsc Res Tech 2002, 57:441-455.
    • (2002) Microsc Res Tech , vol.57 , pp. 441-455
    • Splettstoesser, W.D.1    Schuff-Werner, P.2
  • 37
    • 84878225041 scopus 로고    scopus 로고
    • Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy
    • Dokladny K., Zuhl M.N., Mandell M., Bhattacharya D., Schneider S., Deretic V., et al. Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. J Biol Chem 2013, 288:14959-14972.
    • (2013) J Biol Chem , vol.288 , pp. 14959-14972
    • Dokladny, K.1    Zuhl, M.N.2    Mandell, M.3    Bhattacharya, D.4    Schneider, S.5    Deretic, V.6
  • 38
    • 0025475371 scopus 로고
    • Is glutamine a conditional essential amino acid?
    • Lacey J.M., Wilmore D.W. Is glutamine a conditional essential amino acid?. Nutr Rev 1990, 48:297.
    • (1990) Nutr Rev , vol.48 , pp. 297
    • Lacey, J.M.1    Wilmore, D.W.2
  • 39
    • 84881553223 scopus 로고    scopus 로고
    • Alanyl-glutamine resolves lipopolysaccharide-induced lung injury in mice by modulating the polarization of regulatory T cells and T helper 17 cells
    • Hou Y.C., Pai M.H., Liu J.J., Yeh S.L. Alanyl-glutamine resolves lipopolysaccharide-induced lung injury in mice by modulating the polarization of regulatory T cells and T helper 17 cells. J Nutr Biochem 2013, 24:1555-1563.
    • (2013) J Nutr Biochem , vol.24 , pp. 1555-1563
    • Hou, Y.C.1    Pai, M.H.2    Liu, J.J.3    Yeh, S.L.4
  • 41
    • 84879219249 scopus 로고    scopus 로고
    • Role of glutamine supplementation in critical illness given the results of the REDOXS study
    • Heyland D.K., Dhaliwal R. Role of glutamine supplementation in critical illness given the results of the REDOXS study. JPEN J Parenter Enteral Nutr 2013, 37:442-443.
    • (2013) JPEN J Parenter Enteral Nutr , vol.37 , pp. 442-443
    • Heyland, D.K.1    Dhaliwal, R.2


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