Splicing regulation in spinal muscular atrophy by an RNA structure formed by long-distance interactions

Annals of the New York Academy of Sciences

Volumn 1341, Issue 1, 2015, Pages 176-187

  Singh, Natalia N ^a   Lee, Brian M ^a   Singh, Ravindra N ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Alternative splicing; Antisense oligonucleotide; RNA structure; Spinal muscular atrophy; Survival motor neuron

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CIS ACTING ELEMENT; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; SURVIVAL MOTOR NEURON PROTEIN 2; HNRNP A1; RNA; SMN1 PROTEIN, HUMAN; SMN2 PROTEIN, HUMAN; SURVIVAL MOTOR NEURON PROTEIN 1;

ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CONTROLLED STUDY; EXON; GENE; GENETIC REGULATION; HUMAN; HUMAN CELL; INTERACTIONS WITH RNA; PROTEIN RNA BINDING; RNA STRUCTURE; SITE DIRECTED MUTAGENESIS; SMN2 GENE; SPINAL MUSCULAR ATROPHY; SPLICING DEFECT; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; GENETICS; INTRON; METABOLISM; MOLECULAR GENETICS; MUSCULAR ATROPHY, SPINAL; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; RNA SPLICING;

BASE SEQUENCE; EXONS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; INTRONS; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCULAR ATROPHY, SPINAL; MUTATION; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES, ANTISENSE; RNA; RNA SPLICING; SURVIVAL OF MOTOR NEURON 1 PROTEIN; SURVIVAL OF MOTOR NEURON 2 PROTEIN;

EID: 84926220418     PISSN: 00778923     EISSN: 17496632     Source Type: Journal    
DOI: 10.1111/nyas.12727     Document Type: Article

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