Inflammatory response in heroin addicts undergoing methadone maintenance treatment

Psychiatry Research

Volumn 226, Issue 1, 2015, Pages 230-234

  Chan, Yuan Yu ^a   Yang, Szu Nian ^a   Lin, Jyh Chyang ^a   Chang, Junn Liang ^a   Lin, Jaung Geng ^b   Lo, Wan Yu ^b,c  

^a TAOYUAN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Cytokine; Inflammatory; Methadone

Indexed keywords

DIAMORPHINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; METHADONE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BECK ANXIETY INVENTORY; BECK DEPRESSION INVENTORY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEROIN DEPENDENCE; HUMAN; INFLAMMATION; MALE; METHADONE TREATMENT; PITTSBURGH SLEEP QUALITY INDEX; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TAIWAN; TREATMENT DURATION; CASE CONTROL STUDY; FEMALE; IMMUNOLOGY; METABOLISM; MIDDLE AGED; OPIATE SUBSTITUTION TREATMENT; PROCEDURES;

ADULT; CASE-CONTROL STUDIES; FEMALE; HEROIN; HEROIN DEPENDENCE; HUMANS; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; METHADONE; MIDDLE AGED; OPIATE SUBSTITUTION TREATMENT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84926213148     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2014.12.053     Document Type: Article

References (67)

1. Ackerman K.D., Martino M., Heyman R., Moyna N.M., Rabin B.S. Stressor-induced alteration of cytokine production in multiple sclerosis patients and controls. Psychosomatic Medicine 1998, 60:484-491.
2. Allan S.M., Rothwell N.J. Cytokines and acute neurodegeneration. Nature Reviews Neuroscience 2001, 2:734-744.
3. Alonzo N.C., Bayer B.M. Opioids, immunology, and host defenses of intravenous drug abusers. Infectious Disease Clinics of North America 2002, 16:553-569.
4. Arvin B., Neville L.F., Barone F.C., Feuerstein G.Z. The role of inflammation and cytokines in brain injury. Neuroscience and Biobehavioral Reviews 1996, 20:445-452.
5. Beck A.T., Epstein N., Brown G., Steer R.A. An inventory for measuring clinical anxiety: psychometric properties. Journal of Consulting and Clinical Psychology 1988, 56:893-897.
6. Beck A.T., Steer R.A. Internal consistencies of the original and revised Beck depression inventory. Journal of Clinical Psychology 1984, 40:1365-1367.
7. Beilin B., Shavit Y., Trabekin E., Mordashev B., Mayburd E., Zeidel A., Bessler H. The effects of postoperative pain management on immune response to surgery. Anesthesia and Analgesia 2003, 97:822-827.
8. Berk M., Kapczinski F., Andreazza A.C., Dean O.M., Giorlando F., Maes M., Yucel M., Gama C.S., Dodd S., Dean B., Magalhaes P.V., Amminger P., McGorry P., Malhi G.S. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neuroscience and Biobehavioral Reviews 2011, 35:804-817.
9. Bertolucci M., Perego C., De Simoni M.G. Central opiate modulation of peripheral IL-6 in rats. Neuroreport 1996, 7:1181-1184.
10. Blank S.E., Duncan D.A., Meadows G.G. Suppression of natural killer cell activity by ethanol consumption and food restriction. Alcoholism, Clinical and Experimental Research 1991, 15:16-22.
11. Blum-Degen D., Muller T., Kuhn W., Gerlach M., Przuntek H., Riederer P. Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neuroscience Letters 1995, 202:17-20.
12. Boutin H., LeFeuvre R.A., Horai R., Asano M., Iwakura Y., Rothwell N.J. Role of IL-1alpha and IL-1beta in ischemic brain damage. The Journal of Neuroscience 2001, 21:5528-5534.
13. Buysse D.J., Reynolds C.F., Monk T.H., Berman S.R., Kupfer D.J. The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Research 1989, 28:193-213.
14. Chen S.L., Lee S.Y., Tao P.L., Chang Y.H., Chen S.H., Chu C.H., Chen P.S., Lee I.H., Yeh T.L., Yang Y.K., Hong J.S., Lu R.B. Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment. Journal of Neuroimmune Pharmacology 2012, 7:1025-1033.
15. Chen S.L., Tao P.L., Chu C.H., Chen S.H., Wu H.E., Tseng L.F., Hong J.S., Lu R.B. Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats. Journal of Neuroimmune Pharmacology 2012, 7:444-453.
16. Chu N.N., Xia W., Yu P., Hu L., Zhang R., Cui C.L. Chronic morphine-induced neuronal morphological changes in the ventral tegmental area in rats are reversed by electroacupuncture treatment. Addiction Biology 2008, 13:47-51.
17. Commins S.P., Borish L., Steinke J.W. Immunologic messenger molecules: cytokines, interferons, and chemokines. The Journal of Allergy and Clinical Immunology 2010, 125:S53-72.
18. Cunha-Oliveira T., Rego A.C., Garrido J., Borges F., Macedo T., Oliveira C.R. Neurotoxicity of heroin-cocaine combinations in rat cortical neurons. Toxicology 2010, 276:11-17.
19. Donahoe R.M., Vlahov D. Opiates as potential cofactors in progression of HIV-1 infections to AIDS. Journal of Neuroimmunology 1998, 83:77-87.
20. Drexhage R.C., Knijff E.M., Padmos R.C., Heul-Nieuwenhuijzen L., Beumer W., Versnel M.A., Drexhage H.A. The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder. Expert Review of Neurotherapeutics 2010, 10:59-76.
21. Dyuizen I., Lamash N.E. Histo- and immunocytochemical detection of inducible NOS and TNF-alpha in the locus coeruleus of human opiate addicts. Journal of Chemical Neuroanatomy 2009, 37:65-70.
22. Eisch A.J., Barrot M., Schad C.A., Self D.W., Nestler E.J. Opiates inhibit neurogenesis in the adult rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:7579-7584.
23. Fecho K., Maslonek K.A., Dykstra L.A., Lysle D.T. Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats. The Journal of Pharmacology and Experimental Therapeutics 1996, 276:626-636.
24. Friedman H., Newton C., Klein T.W. Microbial infections, immunomodulation, and drugs of abuse. Clinical Microbiology Reviews 2003, 16:209-219.
25. Gadient R.A., Otten U.H. Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials. Progress in Neurobiology 1997, 52:379-390.
26. Glaser R., Kiecolt-Glaser J. Stress-associated immune suppression and acquired immune deficiency syndrome (AIDS). Advances in Biochemical Psychopharmacology 1988, 44:203-215.
27. Houghtling R.A., Bayer B.M. Rapid elevation of plasma interleukin-6 by morphine is dependent on autonomic stimulation of adrenal gland. The Journal of Pharmacology and Experimental Therapeutics 2002, 300:213-219.
28. Hull M., Fiebich B.L., Lieb K., Strauss S., Berger S.S., Volk B., Bauer J. Interleukin-6-associated inflammatory processes in Alzheimer's disease: new therapeutic options. Neurobiology of Aging 1996, 17:795-800.
29. Hull M., Strauss S., Berger M., Volk B., Bauer J. The participation of interleukin-6, a stress-inducible cytokine, in the pathogenesis of Alzheimer's disease. Behavioural Brain Research 1996, 78:37-41.
30. Kapasi A.A., Gibbons N., Mattana J., Singhal P.C. Morphine stimulates mesangial cell TNF-alpha and nitrite production. Inflammation 2000, 24:463-476.
31. Lucas S.M., Rothwell N.J., Gibson R.M. The role of inflammation in CNS injury and disease. British Journal of Pharmacology 2006, 147(Suppl 1):S232-S240.
32. Maes M. Cytokines in major depression. Biological Psychiatry 1994, 36:498-499.
33. McCarthy D.O., Ouimet M.E., Daun J.M. The effects of noise stress on leukocyte function in rats. Research in Nursing & Health 1992, 15:131-137.
34. McCarthy L., Wetzel M., Sliker J.K., Eisenstein T.K., Rogers T.J. Opioids, opioid receptors, and the immune response. Drug and Alcohol Dependence 2001, 62:111-123.
35. McLachlan C., Crofts N., Wodak A., Crowe S. The effects of methadone on immune function among injecting drug users: a review. Addiction 1993, 88:257-263.
36. Mintzer M.Z., Stitzer M.L. Cognitive impairment in methadone maintenance patients. Drug and Alcohol Dependence 2002, 67:41-51.
37. Munhoz C.D., Garcia-Bueno B., Madrigal J.L., Lepsch L.B., Scavone C., Leza J.C. Stress-induced neuroinflammation: mechanisms and new pharmacological targets. Brazilian Journal of Medical and Biological Research 2008, 41:1037-1046.
38. Munoz-Fernandez M.A., Cano E., O'Donnell C.A., Doyle J., Liew F.Y., Fresno M. Tumor necrosis factor-alpha (TNF-alpha), interferon-gamma, and interleukin-6 but not TNF-beta induce differentiation of neuroblastoma cells: the role of nitric oxide. Journal of Neurochemistry 1994, 62:1330-1336.
39. Myint A.M., Leonard B.E., Steinbusch H.W., Kim Y.K. Th1, Th2, and Th3 cytokine alterations in major depression. Journal of Affective Disorders 2005, 88:167-173.
40. Nelson C.J., Schneider G.M., Lysle D.T. Involvement of central mu- but not delta- or kappa-opioid receptors in immunomodulation. Brain, Behavior, and Immunity 2000, 14:170-184.
41. Neri S., Bruno C.M., Pulvirenti D., Malaguarnera M., Italiano C., Mauceri B., Abate G., Cilio D., Calvagno S., Tsami A., Ignaccolo L., Interlandi D., Prestianni L., Ricchena M., Noto R. Randomized clinical trial to compare the effects of methadone and buprenorphine on the immune system in drug abusers. Psychopharmacology 2005, 179:700-704.
42. Nguyen K.T., Deak T., Owens S.M., Kohno T., Fleshner M., Watkins L.R., Maier S.F. Exposure to acute stress induces brain interleukin-1beta protein in the rat. The Journal of Neuroscience 1998, 18:2239-2246.
43. Pacifici R., di Carlo S., Bacosi A., Pichini S., Zuccaro P. Pharmacokinetics and cytokine production in heroin and morphine-treated mice. International Journal of Immunopharmacology 2000, 22:603-614.
44. Peerzada H., Gandhi J.A., Guimaraes A.J., Nosanchuk J.D., Martinez L.R. Methamphetamine administration modifies leukocyte proliferation and cytokine production in murine tissues. Immunobiology 2013, 218:1063-1068.
45. Peng X., Mosser D.M., Adler M.W., Rogers T.J., Meissler J.J., Eisenstein T.K. Morphine enhances interleukin-12 and the production of other pro-inflammatory cytokines in mouse peritoneal macrophages. Journal of Leukocyte Biology 2000, 68:723-728.
46. Peterson P.K., Molitor T.W., Chao C.C. Mechanisms of morphine-induced immunomodulation. Biochemical Pharmacology 1993, 46:343-348.
47. Peterson P.K., Molitor T.W., Chao C.C. The opioid-cytokine connection. Journal of Neuroimmunology 1998, 83:63-69.
48. Pinteaux E., Trotter P., Simi A. Cell-specific and concentration-dependent actions of interleukin-1 in acute brain inflammation. Cytokine 2009, 45:1-7.
49. Prosser J., London E.D., Galynker II Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: performance and neuroimaging results. Drug and Alcohol Dependence 2009, 104:228-240.
50. Qin L., Wu X., Block M.L., Liu Y., Breese G.R., Hong J.S., Knapp D.J., Crews F.T. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia 2007, 55:453-462.
51. Raghavendra V., Rutkowski M.D., DeLeo J.A. The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. The Journal of Neuroscience 2002, 22:9980-9989.
52. Robinson T.E., Kolb B. Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats. Synapse 1999, 33:160-162.
53. Rodriguez-Pinto I., Agmon-Levin N., Howard A., Shoenfeld Y. Fibromyalgia and cytokines. Immunology Letters 2014, 161:200-203.
54. Sacerdote P. Opioids and the immune system. Palliative Medicine 2006, 20(Suppl 1):S9-S15.
55. Shi J., Zhao L.Y., Copersino M.L., Fang Y.X., Chen Y., Tian J., Deng Y., Shuai Y., Jin J., Lu L. PET imaging of dopamine transporter and drug craving during methadone maintenance treatment and after prolonged abstinence in heroin users. European Journal of Pharmacology 2008, 579:160-166.
56. Simard A.R., Rivest S. Do pathogen exposure and innate immunity cause brain diseases?. Neurological Research 2005, 27:717-725.
57. Sklair-Tavron L., Shi W.X., Lane S.B., Harris H.W., Bunney B.S., Nestler E.J. Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:11202-11207.
58. Slavich G.M., Way B.M., Eisenberger N.I., Taylor S.E. Neural sensitivity to social rejection is associated with inflammatory responses to social stress. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:14817-14822.
59. Sluzewska A., Rybakowski J., Bosmans E., Sobieska M., Berghmans R., Maes M., Wiktorowicz K. Indicators of immune activation in major depression. Psychiatry Research 1996, 64:161-167.
60. Stefano G.B., Scharrer B., Smith E.M., Hughes T.K., Magazine H.I., Bilfinger T.V., Hartman A.R., Fricchione G.L., Liu Y., Makman M.H. Opioid and opiate immunoregulatory processes. Critical Reviews in Immunology 1996, 16:109-144.
61. Tsai P.S., Wang S.Y., Wang M.Y., Su C.T., Yang T.T., Huang C.J., Fang S.C. Psychometric evaluation of the Chinese version of the pittsburgh sleep quality index (CPSQI) in primary insomnia and control subjects. Quality of Life Research 2005, 14:1943-1952.
62. Vallejo R., de Leon-Casasola O., Benyamin R. Opioid therapy and immunosuppression: a review. American Journal of Therapeutics 2004, 11:354-365.
63. Wang Y., Li W., Li Q., Yang W., Zhu J., Wang W. White matter impairment in heroin addicts undergoing methadone maintenance treatment and prolonged abstinence: a preliminary DTI study. Neuroscience Letters 2011, 494:49-53.
64. Zajicova A., Wilczek H., Holan V. The alterations of immunological reactivity in heroin addicts and their normalization in patients maintained on methadone. Folia Biologica 2004, 50:24-28.
65. Zin C.S., Nissen L.M., O'Callaghan J.P., Moore B.J., Smith M.T. Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain management. Pain Medicine 2010, 11:550-561.
66. Zubelewicz B., Braczkowski R., Renshaw D., Harbuz M.S. Central injection of morphine stimulates plasma corticosterone and interleukin (IL)-6 and IL-6R mRNAs in the pituitary and adrenals in adjuvant-induced arthritis. Journal of Biological Regulators and Homeostatic Agents 1999, 13:103-109.
67. Zubelewicz B., Muc-Wierzgon M., Harbuz M.S., Brodziak A. Central single and chronic administration of morphine stimulates corticosterone and interleukin (IL)-6 in adjuvant-induced arthritis. Journal of Physiology and Pharmacology 2000, 51:897-906.