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Volumn 16, Issue 9, 2014, Pages

Role of HDL in Those with Diabetes

Author keywords

apoA I; Atherosclerosis; CETP inhibitor; Fibrates; HDL; HDL functionality; HDL particles; LDL; Niacin; Phospholipids; Reverse cholesterol transport; Sphingosine 1 phosphate; Triglycerides

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ANTILIPEMIC AGENT; FIBRIC ACID DERIVATIVE; NICOTINIC ACID; UNSATURATED FATTY ACID;

EID: 84926094381     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-014-0512-5     Document Type: Review
Times cited : (36)

References (123)
  • 1
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics—2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • PID: 19075105
    • Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, et al. Heart disease and stroke statistics—2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:e21–181.
    • (2009) Circulation , vol.119 , pp. 21-181
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3    De Simone, G.4    Ferguson, T.B.5    Flegal, K.6
  • 2
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • COI: 1:CAS:528:DC%2BD2MXhtVOlu7fM, PID: 16214597
    • Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267–78.
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3    Blackwell, L.4    Buck, G.5    Pollicino, C.6
  • 3
    • 56249123656 scopus 로고    scopus 로고
    • The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in dyslipidaemic patient
    • Fruchart JC, Sacks FM, Hermans MP, Assmann G, Brown WV, Ceska R, et al. The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in dyslipidaemic patient. Diabetes Vasc Dis Res. 2008;5:319–35.
    • (2008) Diabetes Vasc Dis Res , vol.5 , pp. 319-335
    • Fruchart, J.C.1    Sacks, F.M.2    Hermans, M.P.3    Assmann, G.4    Brown, W.V.5    Ceska, R.6
  • 4
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • COI: 1:CAS:528:DC%2BD2MXjtVWltrw%3D, PID: 15755765
    • LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005;352:1425–35.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3    Shear, C.4    Barter, P.5    Fruchart, J.C.6
  • 5
    • 34748887666 scopus 로고    scopus 로고
    • HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events
    • COI: 1:CAS:528:DC%2BD2sXhtFSmtr3M, PID: 17898099
    • Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, Grundy SM, et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med. 2007;357:1301–10.
    • (2007) N Engl J Med , vol.357 , pp. 1301-1310
    • Barter, P.1    Gotto, A.M.2    LaRosa, J.C.3    Maroni, J.4    Szarek, M.5    Grundy, S.M.6
  • 6
    • 77955712458 scopus 로고    scopus 로고
    • HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial
    • COI: 1:CAS:528:DC%2BC3cXpsFenurs%3D, PID: 20655105
    • Ridker PM, Genest J, Boekholdt SM, Libby P, Gotto AM, Nordestgaard BG, et al. HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial. Lancet. 2010;376:333–9.
    • (2010) Lancet , vol.376 , pp. 333-339
    • Ridker, P.M.1    Genest, J.2    Boekholdt, S.M.3    Libby, P.4    Gotto, A.M.5    Nordestgaard, B.G.6
  • 7
    • 84884322622 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy
    • COI: 1:CAS:528:DC%2BC3sXhsVens7rP, PID: 24002795, Groundbreaking study proving that HDL-P concentration is a better marker of residual risk than HDL-C. In the setting of potent statin therapy (JUPITER trial), HDL-P predict CV events, while HDL-C or apo A-I do not
    • Mora S, Glynn RJ, Ridker PM. High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy. Circulation. 2013;128:1189–97. Groundbreaking study proving that HDL-P concentration is a better marker of residual risk than HDL-C. In the setting of potent statin therapy (JUPITER trial), HDL-P predict CV events, while HDL-C or apo A-I do not.
    • (2013) Circulation , vol.128 , pp. 1189-1197
    • Mora, S.1    Glynn, R.J.2    Ridker, P.M.3
  • 8
    • 84884302135 scopus 로고    scopus 로고
    • Translation of high-density lipoprotein function into clinical practice: current prospects and future challenges
    • PID: 24019446, A thorough and up-to-date review on the “pleiotropic” effects of HDL
    • Rosenson RS, Brewer Jr HB, Ansell B, Barter P, Chapman MJ, Heinecke JW, et al. Translation of high-density lipoprotein function into clinical practice: current prospects and future challenges. Circulation. 2013;128:1256–67. A thorough and up-to-date review on the “pleiotropic” effects of HDL.
    • (2013) Circulation , vol.128 , pp. 1256-1267
    • Rosenson, R.S.1    Brewer, H.B.2    Ansell, B.3    Barter, P.4    Chapman, M.J.5    Heinecke, J.W.6
  • 9
    • 79952222810 scopus 로고    scopus 로고
    • HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events
    • COI: 1:CAS:528:DC%2BC3MXjsFCjtL4%3D, PID: 21266551, A new standardized and homogenous classification of HDL is proposed
    • Rosenson RS, Brewer Jr HB, Chapman MJ, Fazio S, Hussain MM, Kontush A, et al. HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events. Clin Chem. 2011;57:392–410. A new standardized and homogenous classification of HDL is proposed.
    • (2011) Clin Chem , vol.57 , pp. 392-410
    • Rosenson, R.S.1    Brewer, H.B.2    Chapman, M.J.3    Fazio, S.4    Hussain, M.M.5    Kontush, A.6
  • 10
    • 84859760161 scopus 로고    scopus 로고
    • Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport
    • PID: 22508840, In-depth review of the concept of macrophage reverses cholesterol transport and the different methods to quantify it
    • Rosenson RS, Brewer Jr HB, Davidson WS, Fayad ZA, Fuster V, Goldstein J, et al. Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. Circulation. 2012;125:1905–19. In-depth review of the concept of macrophage reverses cholesterol transport and the different methods to quantify it.
    • (2012) Circulation , vol.125 , pp. 1905-1919
    • Rosenson, R.S.1    Brewer, H.B.2    Davidson, W.S.3    Fayad, Z.A.4    Fuster, V.5    Goldstein, J.6
  • 11
    • 79953812667 scopus 로고    scopus 로고
    • The beneficial effects of HDL-C on atherosclerosis: rationale and clinical results
    • COI: 1:CAS:528:DC%2BC3MXktl2itro%3D
    • Santos-Gallego CG, Torres F, Badimon JJ. The beneficial effects of HDL-C on atherosclerosis: rationale and clinical results. Clin Lipidol. 2011;6:181–208.
    • (2011) Clin Lipidol , vol.6 , pp. 181-208
    • Santos-Gallego, C.G.1    Torres, F.2    Badimon, J.J.3
  • 12
    • 66349083560 scopus 로고    scopus 로고
    • Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function
    • COI: 1:CAS:528:DC%2BD1MXlslCnsrY%3D, PID: 19325143
    • Davidson WS, Silva RA, Chantepie S, Lagor WR, Chapman MJ, Kontush A. Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function. Arterioscler Thromb Vasc Biol. 2009;29:870–6.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 870-876
    • Davidson, W.S.1    Silva, R.A.2    Chantepie, S.3    Lagor, W.R.4    Chapman, M.J.5    Kontush, A.6
  • 13
    • 79955884728 scopus 로고    scopus 로고
    • Experimental models for the investigation of high-density lipoprotein-mediated cholesterol efflux
    • COI: 1:CAS:528:DC%2BC3MXlsFKhtLo%3D, PID: 21484293
    • Santos-Gallego CG, Giannarelli C, Badimon JJ. Experimental models for the investigation of high-density lipoprotein-mediated cholesterol efflux. Curr Atheroscler Rep. 2011;13:266–76.
    • (2011) Curr Atheroscler Rep , vol.13 , pp. 266-276
    • Santos-Gallego, C.G.1    Giannarelli, C.2    Badimon, J.J.3
  • 14
    • 78651379500 scopus 로고    scopus 로고
    • Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
    • COI: 1:CAS:528:DC%2BC3MXmvFarsA%3D%3D, PID: 21226578
    • Khera AV, Cuchel M, de la Llera-Moya M, Rodrigues A, Burke MF, Jafri K, et al. Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. N Engl J Med. 2011;364:127–35.
    • (2011) N Engl J Med , vol.364 , pp. 127-135
    • Khera, A.V.1    Cuchel, M.2    de la Llera-Moya, M.3    Rodrigues, A.4    Burke, M.F.5    Jafri, K.6
  • 15
    • 84879113852 scopus 로고    scopus 로고
    • Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks
    • COI: 1:CAS:528:DC%2BC3sXptlKru7c%3D, PID: 23520163, Increased ABCA1-mediated cholesterol efflux was associated to reduced risk of prevalent coronary atherosclerotic disease, but it was also paradoxically associated with an increase in the risk of myocardial infarction and cardiovascular death
    • Li XM, Tang WH, Mosior MK, Huang Y, Wu Y, Matter W, et al. Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks. Arterioscler Thromb Vasc Biol. 2013;33:1696–705. Increased ABCA1-mediated cholesterol efflux was associated to reduced risk of prevalent coronary atherosclerotic disease, but it was also paradoxically associated with an increase in the risk of myocardial infarction and cardiovascular death.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1696-1705
    • Li, X.M.1    Tang, W.H.2    Mosior, M.K.3    Huang, Y.4    Wu, Y.5    Matter, W.6
  • 16
    • 84888203299 scopus 로고    scopus 로고
    • Small, dense high-density lipoprotein-3 particles are enriched in negatively charged phospholipids: relevance to cellular cholesterol efflux, antioxidative, antithrombotic, anti-inflammatory, and anti-apoptotic functionalities
    • COI: 1:CAS:528:DC%2BC3sXhslOmsrnP, PID: 24092747, The composition of the HDL lipidome influences HDL functionality. An increase in phosphatidylserine (especially on HDL-S) improves the functionality of HDL-P
    • Camont L, Lhomme M, Rached F, Le Goff W, Negre-Salvayre A, Salvayre R, et al. Small, dense high-density lipoprotein-3 particles are enriched in negatively charged phospholipids: relevance to cellular cholesterol efflux, antioxidative, antithrombotic, anti-inflammatory, and anti-apoptotic functionalities. Arterioscler Thromb Vasc Biol. 2013;33:2715–23. The composition of the HDL lipidome influences HDL functionality. An increase in phosphatidylserine (especially on HDL-S) improves the functionality of HDL-P.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2715-2723
    • Camont, L.1    Lhomme, M.2    Rached, F.3    Le Goff, W.4    Negre-Salvayre, A.5    Salvayre, R.6
  • 17
    • 33847722655 scopus 로고    scopus 로고
    • Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
    • COI: 1:CAS:528:DC%2BD2sXisVKku74%3D, PID: 17322896
    • Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, et al. Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nat Med. 2007;13:340–7.
    • (2007) Nat Med , vol.13 , pp. 340-347
    • Brunham, L.R.1    Kruit, J.K.2    Pape, T.D.3    Timmins, J.M.4    Reuwer, A.Q.5    Vasanji, Z.6
  • 18
    • 77952406884 scopus 로고    scopus 로고
    • Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction
    • COI: 1:CAS:528:DC%2BC3cXlslequr4%3D, PID: 20067955
    • Vergeer M, Brunham LR, Koetsveld J, Kruit JK, Verchere CB, Kastelein JJ, et al. Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction. Diabetes Care. 2010;33:869–74.
    • (2010) Diabetes Care , vol.33 , pp. 869-874
    • Vergeer, M.1    Brunham, L.R.2    Koetsveld, J.3    Kruit, J.K.4    Verchere, C.B.5    Kastelein, J.J.6
  • 19
    • 84858706253 scopus 로고    scopus 로고
    • The emerging role of HDL in glucose metabolism
    • COI: 1:CAS:528:DC%2BC38Xkt1Chs78%3D, PID: 22271188, Interesting review of the “pleiotropic” role of HDL in modulating glucose metabolism
    • Drew BG, Rye KA, Duffy SJ, Barter P, Kingwell BA. The emerging role of HDL in glucose metabolism. Nat Rev Endocrinol. 2012;8:237–45. Interesting review of the “pleiotropic” role of HDL in modulating glucose metabolism.
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 237-245
    • Drew, B.G.1    Rye, K.A.2    Duffy, S.J.3    Barter, P.4    Kingwell, B.A.5
  • 20
    • 65449178091 scopus 로고    scopus 로고
    • High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD1MXksVCku7k%3D, PID: 19349317
    • Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, et al. High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation. 2009;119:2103–11.
    • (2009) Circulation , vol.119 , pp. 2103-2111
    • Drew, B.G.1    Duffy, S.J.2    Formosa, M.F.3    Natoli, A.K.4    Henstridge, D.C.5    Penfold, S.A.6
  • 21
    • 34547696757 scopus 로고    scopus 로고
    • Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism
    • COI: 1:CAS:528:DC%2BD2sXos1Cjt74%3D, PID: 17639303
    • Han R, Lai R, Ding Q, Wang Z, Luo X, Zhang Y, et al. Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism. Diabetologia. 2007;50:1960–8.
    • (2007) Diabetologia , vol.50 , pp. 1960-1968
    • Han, R.1    Lai, R.2    Ding, Q.3    Wang, Z.4    Luo, X.5    Zhang, Y.6
  • 22
    • 79953206962 scopus 로고    scopus 로고
    • Reconstituted high-density lipoprotein infusion modulates fatty acid metabolism in patients with type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BC3MXisFKrsr8%3D, PID: 21224289
    • Drew BG, Carey AL, Natoli AK, Formosa MF, Vizi D, Reddy-Luthmoodoo M, et al. Reconstituted high-density lipoprotein infusion modulates fatty acid metabolism in patients with type 2 diabetes mellitus. J Lipid Res. 2011;52:572–81.
    • (2011) J Lipid Res , vol.52 , pp. 572-581
    • Drew, B.G.1    Carey, A.L.2    Natoli, A.K.3    Formosa, M.F.4    Vizi, D.5    Reddy-Luthmoodoo, M.6
  • 23
    • 33749012804 scopus 로고    scopus 로고
    • High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor
    • COI: 1:CAS:528:DC%2BD28XpslSrs7c%3D, PID: 16982942
    • Theilmeier G, Schmidt C, Herrmann J, Keul P, Schafers M, Herrgott I, et al. High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. Circulation. 2006;114:1403–9.
    • (2006) Circulation , vol.114 , pp. 1403-1409
    • Theilmeier, G.1    Schmidt, C.2    Herrmann, J.3    Keul, P.4    Schafers, M.5    Herrgott, I.6
  • 24
    • 0037458924 scopus 로고    scopus 로고
    • High-density lipoproteins protect isolated rat hearts from ischemia-reperfusion injury by reducing cardiac tumor necrosis factor-alpha content and enhancing prostaglandin release
    • COI: 1:CAS:528:DC%2BD3sXht1Cmt7s%3D, PID: 12595346
    • Calabresi L, Rossoni G, Gomaraschi M, Sisto F, Berti F, Franceschini G. High-density lipoproteins protect isolated rat hearts from ischemia-reperfusion injury by reducing cardiac tumor necrosis factor-alpha content and enhancing prostaglandin release. Circ Res. 2003;92:330–7.
    • (2003) Circ Res , vol.92 , pp. 330-337
    • Calabresi, L.1    Rossoni, G.2    Gomaraschi, M.3    Sisto, F.4    Berti, F.5    Franceschini, G.6
  • 25
    • 0347128182 scopus 로고    scopus 로고
    • Synthetic high-density lipoproteins exert cardioprotective effects in myocardial ischemia/reperfusion injury
    • COI: 1:CAS:528:DC%2BD2cXmsFeitA%3D%3D, PID: 14566009
    • Rossoni G, Gomaraschi M, Berti F, Sirtori CR, Franceschini G, Calabresi L. Synthetic high-density lipoproteins exert cardioprotective effects in myocardial ischemia/reperfusion injury. J Pharmacol Exp Ther. 2004;308:79–84.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 79-84
    • Rossoni, G.1    Gomaraschi, M.2    Berti, F.3    Sirtori, C.R.4    Franceschini, G.5    Calabresi, L.6
  • 26
    • 40949107218 scopus 로고    scopus 로고
    • Apolipoprotein A-IMilano/POPC complex attenuates post-ischemic ventricular dysfunction in the isolated rabbit heart
    • COI: 1:CAS:528:DC%2BD1cXktFCksLo%3D, PID: 17945238
    • Marchesi M, Booth EA, Rossoni G, Garcia RA, Hill KR, Sirtori CR, et al. Apolipoprotein A-IMilano/POPC complex attenuates post-ischemic ventricular dysfunction in the isolated rabbit heart. Atherosclerosis. 2008;197:572–8.
    • (2008) Atherosclerosis , vol.197 , pp. 572-578
    • Marchesi, M.1    Booth, E.A.2    Rossoni, G.3    Garcia, R.A.4    Hill, K.R.5    Sirtori, C.R.6
  • 27
    • 68749100860 scopus 로고    scopus 로고
    • High high-density lipoprotein-cholesterol reduces risk and extent of percutaneous coronary intervention-related myocardial infarction and improves long-term outcome in patients undergoing elective percutaneous coronary intervention
    • COI: 1:CAS:528:DC%2BD1MXpsVars7w%3D, PID: 19474052
    • Sattler KJ, Herrmann J, Yun S, Lehmann N, Wang Z, Heusch G, et al. High high-density lipoprotein-cholesterol reduces risk and extent of percutaneous coronary intervention-related myocardial infarction and improves long-term outcome in patients undergoing elective percutaneous coronary intervention. Eur Heart J. 2009;30:1894–902.
    • (2009) Eur Heart J , vol.30 , pp. 1894-1902
    • Sattler, K.J.1    Herrmann, J.2    Yun, S.3    Lehmann, N.4    Wang, Z.5    Heusch, G.6
  • 28
    • 0028859490 scopus 로고
    • Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell co-cultures
    • PID: 8675645
    • Van Lenten BJ, Hama SY, de Beer FC, Stafforini DM, McIntyre TM, Prescott SM, et al. Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell co-cultures. J Clin Invest. 1995;96:2758–67.
    • (1995) J Clin Invest , vol.96 , pp. 2758-2767
    • Van Lenten, B.J.1    Hama, S.Y.2    de Beer, F.C.3    Stafforini, D.M.4    McIntyre, T.M.5    Prescott, S.M.6
  • 29
    • 0035826840 scopus 로고    scopus 로고
    • High-density lipoprotein loses its anti-inflammatory properties during acute Influenza A infection
    • PID: 11342478
    • Van Lenten BJ, Wagner AC, Nayak DP, Hama S, Navab M, Fogelman AM. High-density lipoprotein loses its anti-inflammatory properties during acute Influenza A infection. Circulation. 2001;103:2283–8.
    • (2001) Circulation , vol.103 , pp. 2283-2288
    • Van Lenten, B.J.1    Wagner, A.C.2    Nayak, D.P.3    Hama, S.4    Navab, M.5    Fogelman, A.M.6
  • 30
    • 80053431876 scopus 로고    scopus 로고
    • Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3MXhtl2is73J, PID: 21852676
    • Morgantini C, Natali A, Boldrini B, Imaizumi S, Navab M, Fogelman AM, et al. Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. Diabetes. 2011;60:2617–23.
    • (2011) Diabetes , vol.60 , pp. 2617-2623
    • Morgantini, C.1    Natali, A.2    Boldrini, B.3    Imaizumi, S.4    Navab, M.5    Fogelman, A.M.6
  • 31
    • 4344577056 scopus 로고    scopus 로고
    • Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease
    • COI: 1:CAS:528:DC%2BD2cXmvVelsro%3D, PID: 15314690
    • Zheng L, Nukuna B, Brennan ML, Sun M, Goormastic M, Settle M, et al. Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest. 2004;114:529–41.
    • (2004) J Clin Invest , vol.114 , pp. 529-541
    • Zheng, L.1    Nukuna, B.2    Brennan, M.L.3    Sun, M.4    Goormastic, M.5    Settle, M.6
  • 32
    • 84893772037 scopus 로고    scopus 로고
    • Huang Y, Didonato JA, Levison BS, Schmitt D, Li L, Wu Y, Buffa J, et al. An abundant dysfunctional apolipoprotein A1 in human atheroma. Nat Med. 2014;20:193–203. Apo A-I is oxidized at the position Trp72 by MPO in atheroma lesions, which reduces HDL functionality. This Trp72-oxidized apo A-I can subsequently diffuse back into plasma, thus, giving a mechanistic explanation for HDL dysfunction
    • Huang Y, Didonato JA, Levison BS, Schmitt D, Li L, Wu Y, Buffa J, et al. An abundant dysfunctional apolipoprotein A1 in human atheroma. Nat Med. 2014;20:193–203. Apo A-I is oxidized at the position Trp72 by MPO in atheroma lesions, which reduces HDL functionality. This Trp72-oxidized apo A-I can subsequently diffuse back into plasma, thus, giving a mechanistic explanation for HDL dysfunction.
  • 33
    • 34447117721 scopus 로고    scopus 로고
    • Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties
    • COI: 1:CAS:528:DC%2BD2sXnt1Kisb4%3D, PID: 17579831
    • Hoang A, Murphy AJ, Coughlan MT, Thomas MC, Forbes JM, O'Brien R, et al. Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties. Diabetologia. 2007;50:1770–9.
    • (2007) Diabetologia , vol.50 , pp. 1770-1779
    • Hoang, A.1    Murphy, A.J.2    Coughlan, M.T.3    Thomas, M.C.4    Forbes, J.M.5    O'Brien, R.6
  • 34
    • 10744224101 scopus 로고    scopus 로고
    • Inflammatory/anti-inflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment
    • COI: 1:CAS:528:DC%2BD3sXptV2jurw%3D, PID: 14638544
    • Ansell BJ, Navab M, Hama S, Kamranpour N, Fonarow G, Hough G, et al. Inflammatory/anti-inflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment. Circulation. 2003;108:2751–6.
    • (2003) Circulation , vol.108 , pp. 2751-2756
    • Ansell, B.J.1    Navab, M.2    Hama, S.3    Kamranpour, N.4    Fonarow, G.5    Hough, G.6
  • 35
    • 79959919890 scopus 로고    scopus 로고
    • Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease
    • COI: 1:CAS:528:DC%2BC3MXovVKgurk%3D, PID: 21701070
    • Besler C, Heinrich K, Rohrer L, Doerries C, Riwanto M, Shih DM, et al. Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. J Clin Invest. 2011;121:2693–708.
    • (2011) J Clin Invest , vol.121 , pp. 2693-2708
    • Besler, C.1    Heinrich, K.2    Rohrer, L.3    Doerries, C.4    Riwanto, M.5    Shih, D.M.6
  • 36
    • 84874469648 scopus 로고    scopus 로고
    • Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling
    • COI: 1:CAS:528:DC%2BC3sXivFOmurs%3D, PID: 23349247, The composition of the HDL proteome influences HDL functionality, especially regarding anti-apoptotic effects on endothelial cells
    • Riwanto M, Rohrer L, Roschitzki B, Besler C, Mocharla P, Mueller M, et al. Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling. Circulation. 2013;127:891–904. The composition of the HDL proteome influences HDL functionality, especially regarding anti-apoptotic effects on endothelial cells.
    • (2013) Circulation , vol.127 , pp. 891-904
    • Riwanto, M.1    Rohrer, L.2    Roschitzki, B.3    Besler, C.4    Mocharla, P.5    Mueller, M.6
  • 37
    • 74549172922 scopus 로고    scopus 로고
    • Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy
    • COI: 1:CAS:528:DC%2BD1MXhs1WjtrjJ, PID: 20026785
    • Sorrentino SA, Besler C, Rohrer L, Meyer M, Heinrich K, Bahlmann FH, et al. Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy. Circulation. 2010;121:110–22.
    • (2010) Circulation , vol.121 , pp. 110-122
    • Sorrentino, S.A.1    Besler, C.2    Rohrer, L.3    Meyer, M.4    Heinrich, K.5    Bahlmann, F.H.6
  • 38
    • 0033550010 scopus 로고    scopus 로고
    • C-Reactive protein, serum amyloid A protein, and coronary events
    • COI: 1:STN:280:DyaK1MvkvVSkug%3D%3D, PID: 10517745
    • Choudhury RP, Leyva F. C-Reactive protein, serum amyloid A protein, and coronary events. Circulation. 1999;100:e65–6.
    • (1999) Circulation , vol.100 , pp. 65-66
    • Choudhury, R.P.1    Leyva, F.2
  • 39
    • 16844382469 scopus 로고    scopus 로고
    • Defective antioxidative activity of small dense HDL3 particles in type 2 diabetes: relationship to elevated oxidative stress and hyperglycaemia
    • COI: 1:CAS:528:DC%2BD2MXisVCitbg%3D, PID: 15729582
    • Nobecourt E, Jacqueminet S, Hansel B, Chantepie S, Grimaldi A, Chapman MJ, et al. Defective antioxidative activity of small dense HDL3 particles in type 2 diabetes: relationship to elevated oxidative stress and hyperglycaemia. Diabetologia. 2005;48:529–38.
    • (2005) Diabetologia , vol.48 , pp. 529-538
    • Nobecourt, E.1    Jacqueminet, S.2    Hansel, B.3    Chantepie, S.4    Grimaldi, A.5    Chapman, M.J.6
  • 40
    • 39449100874 scopus 로고    scopus 로고
    • Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity
    • PID: 17868679, COI: 1:CAS:528:DC%2BD1cXisVSlt74%3D
    • de Souza JA, Vindis C, Hansel B, Negre-Salvayre A, Therond P, Serrano Jr CV, et al. Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity. Atherosclerosis. 2008;197:84–94.
    • (2008) Atherosclerosis , vol.197 , pp. 84-94
    • de Souza, J.A.1    Vindis, C.2    Hansel, B.3    Negre-Salvayre, A.4    Therond, P.5    Serrano, C.V.6
  • 41
    • 73849121438 scopus 로고    scopus 로고
    • HDL3-mediated inactivation of LDL-associated phospholipid hydroperoxides is determined by the redox status of apolipoprotein A-I and HDL particle surface lipid rigidity: relevance to inflammation and atherogenesis
    • COI: 1:CAS:528:DC%2BD1MXhtl2qtbnE, PID: 19762782
    • Zerrad-Saadi A, Therond P, Chantepie S, Couturier M, Rye KA, Chapman MJ, et al. HDL3-mediated inactivation of LDL-associated phospholipid hydroperoxides is determined by the redox status of apolipoprotein A-I and HDL particle surface lipid rigidity: relevance to inflammation and atherogenesis. Arterioscler Thromb Vasc Biol. 2009;29:2169–75.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 2169-2175
    • Zerrad-Saadi, A.1    Therond, P.2    Chantepie, S.3    Couturier, M.4    Rye, K.A.5    Chapman, M.J.6
  • 42
    • 0037317156 scopus 로고    scopus 로고
    • Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance
    • COI: 1:CAS:528:DC%2BD3sXhtFansLw%3D, PID: 12540621
    • Garvey WT, Kwon S, Zheng D, Shaughnessy S, Wallace P, Hutto A, et al. Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance. Diabetes. 2003;52:453–62.
    • (2003) Diabetes , vol.52 , pp. 453-462
    • Garvey, W.T.1    Kwon, S.2    Zheng, D.3    Shaughnessy, S.4    Wallace, P.5    Hutto, A.6
  • 43
    • 0024501678 scopus 로고
    • High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies
    • COI: 1:STN:280:DyaL1M%2FptVWjtg%3D%3D, PID: 2642759
    • Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, Knoke JD, et al. High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation. 1989;79:8–15.
    • (1989) Circulation , vol.79 , pp. 8-15
    • Gordon, D.J.1    Probstfield, J.L.2    Garrison, R.J.3    Neaton, J.D.4    Castelli, W.P.5    Knoke, J.D.6
  • 44
    • 37449021638 scopus 로고    scopus 로고
    • Clinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterol
    • COI: 1:CAS:528:DC%2BD1cXislCruw%3D%3D, PID: 18174036
    • deGoma EM, Leeper NJ, Heidenreich PA. Clinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterol. J Am Coll Cardiol. 2008;51:49–55.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 49-55
    • deGoma, E.M.1    Leeper, N.J.2    Heidenreich, P.A.3
  • 45
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian randomisation study
    • COI: 1:CAS:528:DC%2BC38Xnt1Cmsrc%3D, PID: 22607825, Genetic variation in the activity of endothelial lipase (which increases HDL-C levels) is not associated with risk of myocardial infarction. However, we must take into account that EL increases HDL-C without affecting the concentration of HDL-P
    • Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK, et al. Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian randomisation study. Lancet. 2012;380:572–80. Genetic variation in the activity of endothelial lipase (which increases HDL-C levels) is not associated with risk of myocardial infarction. However, we must take into account that EL increases HDL-C without affecting the concentration of HDL-P.
    • (2012) Lancet , vol.380 , pp. 572-580
    • Voight, B.F.1    Peloso, G.M.2    Orho-Melander, M.3    Frikke-Schmidt, R.4    Barbalic, M.5    Jensen, M.K.6
  • 46
    • 84860916377 scopus 로고    scopus 로고
    • Changes in HDL cholesterol and cardiovascular outcomes after lipid modification therapy
    • COI: 1:CAS:528:DC%2BC38XhtVShtL7K, PID: 22447463, In a subanalysis of 1148 participants in EPIC-Norfolk and Rotterdam studies, changes in HDL-C after lipid-modifying therapy did not predict CV risk
    • Ray K, Wainwright NW, Visser L, Witteman J, Breteler M, Ambegaonkar B, et al. Changes in HDL cholesterol and cardiovascular outcomes after lipid modification therapy. Heart. 2012;98:780–5. In a subanalysis of 1148 participants in EPIC-Norfolk and Rotterdam studies, changes in HDL-C after lipid-modifying therapy did not predict CV risk.
    • (2012) Heart , vol.98 , pp. 780-785
    • Ray, K.1    Wainwright, N.W.2    Visser, L.3    Witteman, J.4    Breteler, M.5    Ambegaonkar, B.6
  • 47
    • 79953867783 scopus 로고    scopus 로고
    • Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis
    • PID: 19221140, COI: 1:CAS:528:DC%2BD1MXktlGltLo%3D
    • Briel M, Ferreira-Gonzalez I, You JJ, Karanicolas PJ, Akl EA, Wu P, et al. Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. BMJ. 2009;338:b92.
    • (2009) BMJ , vol.338 , pp. 92
    • Briel, M.1    Ferreira-Gonzalez, I.2    You, J.J.3    Karanicolas, P.J.4    Akl, E.A.5    Wu, P.6
  • 48
  • 49
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • COI: 1:CAS:528:DC%2BC38XhslyltrvK, PID: 23126252, In 15871 patients with a recent ACS, the CETP inhibitor dalcetrapib increased HDL-C levels but did not reduce the risk of recurrent cardiovascular events
    • Schwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012;367:2089–99. In 15871 patients with a recent ACS, the CETP inhibitor dalcetrapib increased HDL-C levels but did not reduce the risk of recurrent cardiovascular events.
    • (2012) N Engl J Med , vol.367 , pp. 2089-2099
    • Schwartz, G.G.1    Olsson, A.G.2    Abt, M.3    Ballantyne, C.M.4    Barter, P.J.5    Brumm, J.6
  • 51
    • 0037126373 scopus 로고    scopus 로고
    • Measurement issues related to lipoprotein heterogeneity
    • COI: 1:CAS:528:DC%2BD38XptFarsb0%3D, PID: 12419478
    • Otvos JD, Jeyarajah EJ, Cromwell WC. Measurement issues related to lipoprotein heterogeneity. Am J Cardiol. 2002;90:22i–9.
    • (2002) Am J Cardiol , vol.90 , pp. 22-29
    • Otvos, J.D.1    Jeyarajah, E.J.2    Cromwell, W.C.3
  • 52
    • 35248829949 scopus 로고    scopus 로고
    • Lipoprotein particles, insulin, adiponectin, C-reactive protein and risk of coronary heart disease among men with metabolic syndrome
    • COI: 1:CAS:528:DC%2BD2sXhtF2hur%2FP, PID: 17011566
    • Kuller LH, Grandits G, Cohen JD, Neaton JD, Prineas R. Lipoprotein particles, insulin, adiponectin, C-reactive protein and risk of coronary heart disease among men with metabolic syndrome. Atherosclerosis. 2007;195:122–8.
    • (2007) Atherosclerosis , vol.195 , pp. 122-128
    • Kuller, L.H.1    Grandits, G.2    Cohen, J.D.3    Neaton, J.D.4    Prineas, R.5
  • 53
    • 84864767131 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis)
    • COI: 1:CAS:528:DC%2BC38XhtFKntr3L, PID: 22796256, In 5598 participants of the MESA trial, HDL-C did not predict carotid intima-media thickness (cIMT) of CVD events after adjusting by LDL-P. However, HDL-P (measured by NMR) predicted both cIMT and CV events, even after adjusting by LDL-P and HDL-C
    • Mackey RH, Greenland P, Goff Jr DC, Lloyd-Jones D, Sibley CT, Mora S. High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis). J Am Coll Cardiol. 2012;60:508–16. In 5598 participants of the MESA trial, HDL-C did not predict carotid intima-media thickness (cIMT) of CVD events after adjusting by LDL-P. However, HDL-P (measured by NMR) predicted both cIMT and CV events, even after adjusting by LDL-P and HDL-C.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 508-516
    • Mackey, R.H.1    Greenland, P.2    Goff, D.C.3    Lloyd-Jones, D.4    Sibley, C.T.5    Mora, S.6
  • 54
    • 84898748566 scopus 로고    scopus 로고
    • High-density lipoprotein particle subclass heterogeneity and incident coronary heart disease
    • PID: 24248942, Another proof that HDL-P (and not HDL-C) explains CVD risk. Twenty-six thousand, three hundred thirty-two women were followed-up for 17 years. Concentrations of HDL-P (specifically of HDL-S, HDL-M and HDL-L) were inversely associated with CVD risk, even after adjusting for HDL-C
    • Akinkuolie AO, Paynter NP, Padmanabhan L, Mora S. High-density lipoprotein particle subclass heterogeneity and incident coronary heart disease. Circ Cardiovasc Qual Outcomes. 2014;7:55–63. Another proof that HDL-P (and not HDL-C) explains CVD risk. Twenty-six thousand, three hundred thirty-two women were followed-up for 17 years. Concentrations of HDL-P (specifically of HDL-S, HDL-M and HDL-L) were inversely associated with CVD risk, even after adjusting for HDL-C.
    • (2014) Circ Cardiovasc Qual Outcomes , vol.7 , pp. 55-63
    • Akinkuolie, A.O.1    Paynter, N.P.2    Padmanabhan, L.3    Mora, S.4
  • 55
    • 33645741889 scopus 로고    scopus 로고
    • Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial
    • COI: 1:CAS:528:DC%2BD28XisFygs70%3D, PID: 16534013
    • Otvos JD, Collins D, Freedman DS, Shalaurova I, Schaefer EJ, McNamara JR, et al. Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Circulation. 2006;113:1556–63.
    • (2006) Circulation , vol.113 , pp. 1556-1563
    • Otvos, J.D.1    Collins, D.2    Freedman, D.S.3    Shalaurova, I.4    Schaefer, E.J.5    McNamara, J.R.6
  • 56
    • 77955423268 scopus 로고    scopus 로고
    • Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility
    • COI: 1:CAS:528:DC%2BC3cXpslWnt7c%3D, PID: 20644014
    • Vergeer M, Boekholdt SM, Sandhu MS, Ricketts SL, Wareham NJ, Brown MJ, et al. Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation. 2010;122:470–7.
    • (2010) Circulation , vol.122 , pp. 470-477
    • Vergeer, M.1    Boekholdt, S.M.2    Sandhu, M.S.3    Ricketts, S.L.4    Wareham, N.J.5    Brown, M.J.6
  • 58
    • 34249655774 scopus 로고    scopus 로고
    • Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis
    • COI: 1:CAS:528:DC%2BD2sXmvVGrtLk%3D, PID: 17533202
    • Kodama S, Tanaka S, Saito K, Shu M, Sone Y, Onitake F, et al. Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis. Arch Intern Med. 2007;167:999–1008.
    • (2007) Arch Intern Med , vol.167 , pp. 999-1008
    • Kodama, S.1    Tanaka, S.2    Saito, K.3    Shu, M.4    Sone, Y.5    Onitake, F.6
  • 59
    • 33845448954 scopus 로고    scopus 로고
    • Effect of a short-term diet and exercise intervention on inflammatory/anti-inflammatory properties of HDL in overweight/obese men with cardiovascular risk factors
    • COI: 1:CAS:528:DC%2BD28Xhtlent7bE, PID: 16902063
    • Roberts CK, Ng C, Hama S, Eliseo AJ, Barnard RJ. Effect of a short-term diet and exercise intervention on inflammatory/anti-inflammatory properties of HDL in overweight/obese men with cardiovascular risk factors. J Appl Physiol. 2006;101:1727–32.
    • (2006) J Appl Physiol , vol.101 , pp. 1727-1732
    • Roberts, C.K.1    Ng, C.2    Hama, S.3    Eliseo, A.J.4    Barnard, R.J.5
  • 60
    • 0025820598 scopus 로고
    • The effects on plasma lipoproteins of a prudent weight-reducing diet, with or without exercise, in overweight men and women
    • COI: 1:STN:280:DyaK3MzgsVGhuw%3D%3D, PID: 1852180
    • Wood PD, Stefanick ML, Williams PT, Haskell WL. The effects on plasma lipoproteins of a prudent weight-reducing diet, with or without exercise, in overweight men and women. N Engl J Med. 1991;325:461–6.
    • (1991) N Engl J Med , vol.325 , pp. 461-466
    • Wood, P.D.1    Stefanick, M.L.2    Williams, P.T.3    Haskell, W.L.4
  • 61
    • 0026781014 scopus 로고
    • Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis
    • COI: 1:CAS:528:DyaK38XlslSju7Y%3D, PID: 1386186
    • Dattilo AM, Kris-Etherton PM. Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am J Clin Nutr. 1992;56:320–8.
    • (1992) Am J Clin Nutr , vol.56 , pp. 320-328
    • Dattilo, A.M.1    Kris-Etherton, P.M.2
  • 62
    • 0019424849 scopus 로고
    • Increase of adipose tissue lipoprotein lipase activity with weight loss
    • COI: 1:CAS:528:DyaL3MXitVKltLg%3D, PID: 7229033
    • Schwartz RS, Brunzell JD. Increase of adipose tissue lipoprotein lipase activity with weight loss. J Clin Invest. 1981;67:1425–30.
    • (1981) J Clin Invest , vol.67 , pp. 1425-1430
    • Schwartz, R.S.1    Brunzell, J.D.2
  • 63
    • 0023626986 scopus 로고
    • Plasma lipoproteins and lipase and lecithin:cholesterol acyltransferase activities in obese subjects before and after weight reduction
    • COI: 1:CAS:528:DyaL1cXkt1yg, PID: 3667889
    • Weisweiler P. Plasma lipoproteins and lipase and lecithin:cholesterol acyltransferase activities in obese subjects before and after weight reduction. J Clin Endocrinol Metab. 1987;65:969–73.
    • (1987) J Clin Endocrinol Metab , vol.65 , pp. 969-973
    • Weisweiler, P.1
  • 64
    • 79953888447 scopus 로고    scopus 로고
    • Effect of bariatric surgery-induced weight loss on SR-BI-, ABCG1-, and ABCA1-mediated cellular cholesterol efflux in obese women
    • COI: 1:CAS:528:DC%2BC3MXltF2qtbc%3D, PID: 21289254
    • Aron-Wisnewsky J, Julia Z, Poitou C, Bouillot JL, Basdevant A, Chapman MJ, et al. Effect of bariatric surgery-induced weight loss on SR-BI-, ABCG1-, and ABCA1-mediated cellular cholesterol efflux in obese women. J Clin Endocrinol Metab. 2011;96:1151–9.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 1151-1159
    • Aron-Wisnewsky, J.1    Julia, Z.2    Poitou, C.3    Bouillot, J.L.4    Basdevant, A.5    Chapman, M.J.6
  • 65
    • 0024503699 scopus 로고
    • Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data
    • COI: 1:STN:280:DyaL1M3ivFKiuw%3D%3D, PID: 2496857
    • Craig WY, Palomaki GE, Haddow JE. Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data. BMJ. 1989;298:784–8.
    • (1989) BMJ , vol.298 , pp. 784-788
    • Craig, W.Y.1    Palomaki, G.E.2    Haddow, J.E.3
  • 66
    • 0031008675 scopus 로고    scopus 로고
    • Effect of smoking cessation on lipoprotein A-I and lipoprotein A-I:A-II levels
    • COI: 1:CAS:528:DyaK2sXjvVansLg%3D, PID: 9186310
    • Richard F, Marecaux N, Dallongeville J, Devienne M, Tiem N, Fruchart JC, et al. Effect of smoking cessation on lipoprotein A-I and lipoprotein A-I:A-II levels. Metabolism. 1997;46:711–5.
    • (1997) Metabolism , vol.46 , pp. 711-715
    • Richard, F.1    Marecaux, N.2    Dallongeville, J.3    Devienne, M.4    Tiem, N.5    Fruchart, J.C.6
  • 67
    • 0141737742 scopus 로고    scopus 로고
    • The effects of cessation from cigarette smoking on the lipid and lipoprotein profiles: a meta-analysis
    • COI: 1:CAS:528:DC%2BD3sXnsVWruro%3D, PID: 14507483
    • Maeda K, Noguchi Y, Fukui T. The effects of cessation from cigarette smoking on the lipid and lipoprotein profiles: a meta-analysis. Prev Med. 2003;37:283–90.
    • (2003) Prev Med , vol.37 , pp. 283-290
    • Maeda, K.1    Noguchi, Y.2    Fukui, T.3
  • 68
    • 0033591854 scopus 로고    scopus 로고
    • Alcohol intake and the risk of coronary heart disease mortality in persons with older-onset diabetes mellitus
    • COI: 1:STN:280:DyaK1MzkvFymtw%3D%3D, PID: 10422992
    • Valmadrid CT, Klein R, Moss SE, Klein BE, Cruickshanks KJ. Alcohol intake and the risk of coronary heart disease mortality in persons with older-onset diabetes mellitus. JAMA. 1999;282:239–46.
    • (1999) JAMA , vol.282 , pp. 239-246
    • Valmadrid, C.T.1    Klein, R.2    Moss, S.E.3    Klein, B.E.4    Cruickshanks, K.J.5
  • 71
    • 84875787136 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with a Mediterranean diet
    • COI: 1:CAS:528:DC%2BC3sXls1akt7c%3D, PID: 23432189, This randomized control trial convincingly proves that Mediterranean diet (with supplementation with olive oil and nuts) results in reduced mortality and lower cardiovascular risk in patients with cardiovascular disease
    • Estruch R, Ros E, Salas-Salvado J, Covas MI, Corella D, Aros F, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368:1279–90. This randomized control trial convincingly proves that Mediterranean diet (with supplementation with olive oil and nuts) results in reduced mortality and lower cardiovascular risk in patients with cardiovascular disease.
    • (2013) N Engl J Med , vol.368 , pp. 1279-1290
    • Estruch, R.1    Ros, E.2    Salas-Salvado, J.3    Covas, M.I.4    Corella, D.5    Aros, F.6
  • 72
    • 33746851173 scopus 로고    scopus 로고
    • Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function
    • COI: 1:CAS:528:DC%2BD28XotFWksb8%3D, PID: 16904539
    • Nicholls SJ, Lundman P, Harmer JA, Cutri B, Griffiths KA, Rye KA, et al. Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function. J Am Coll Cardiol. 2006;48:715–20.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 715-720
    • Nicholls, S.J.1    Lundman, P.2    Harmer, J.A.3    Cutri, B.4    Griffiths, K.A.5    Rye, K.A.6
  • 73
    • 0033608866 scopus 로고    scopus 로고
    • Glycaemic index as a determinant of serum HDL-cholesterol concentration
    • COI: 1:STN:280:DyaK1M3htlCnsQ%3D%3D, PID: 10199351
    • Frost G, Leeds AA, Dore CJ, Madeiros S, Brading S, Dornhorst A. Glycaemic index as a determinant of serum HDL-cholesterol concentration. Lancet. 1999;353:1045–8.
    • (1999) Lancet , vol.353 , pp. 1045-1048
    • Frost, G.1    Leeds, A.A.2    Dore, C.J.3    Madeiros, S.4    Brading, S.5    Dornhorst, A.6
  • 74
    • 0035952236 scopus 로고    scopus 로고
    • Glycemic index and serum high-density lipoprotein cholesterol concentration among us adults
    • COI: 1:STN:280:DC%2BD3M3jsVagtA%3D%3D, PID: 11252117
    • Ford ES, Liu S. Glycemic index and serum high-density lipoprotein cholesterol concentration among us adults. Arch Intern Med. 2001;161:572–6.
    • (2001) Arch Intern Med , vol.161 , pp. 572-576
    • Ford, E.S.1    Liu, S.2
  • 75
    • 35148864410 scopus 로고    scopus 로고
    • Dietary glycemic index and glycemic load are associated with high-density-lipoprotein cholesterol at baseline but not with increased risk of diabetes in the Whitehall II study
    • COI: 1:CAS:528:DC%2BD2sXhtFyks7bM, PID: 17921375
    • Mosdol A, Witte DR, Frost G, Marmot MG, Brunner EJ. Dietary glycemic index and glycemic load are associated with high-density-lipoprotein cholesterol at baseline but not with increased risk of diabetes in the Whitehall II study. Am J Clin Nutr. 2007;86:988–94.
    • (2007) Am J Clin Nutr , vol.86 , pp. 988-994
    • Mosdol, A.1    Witte, D.R.2    Frost, G.3    Marmot, M.G.4    Brunner, E.J.5
  • 76
    • 66549089455 scopus 로고    scopus 로고
    • Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study
    • COI: 1:CAS:528:DC%2BD1MXnvVOqs7k%3D, PID: 19265025
    • Rosenson RS, Otvos JD, Hsia J. Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study. Diabetes Care. 2009;32:1087–91.
    • (2009) Diabetes Care , vol.32 , pp. 1087-1091
    • Rosenson, R.S.1    Otvos, J.D.2    Hsia, J.3
  • 77
    • 0033049802 scopus 로고    scopus 로고
    • Metabolic basis of high density lipoproteins and apolipoprotein A-I increase by HMG-CoA reductase inhibition in healthy subjects and a patient with coronary artery disease
    • COI: 1:CAS:528:DyaK1MXkt1eltr4%3D, PID: 10381291
    • Schaefer JR, Schweer H, Ikewaki K, Stracke H, Seyberth HJ, Kaffarnik H, et al. Metabolic basis of high density lipoproteins and apolipoprotein A-I increase by HMG-CoA reductase inhibition in healthy subjects and a patient with coronary artery disease. Atherosclerosis. 1999;144:177–84.
    • (1999) Atherosclerosis , vol.144 , pp. 177-184
    • Schaefer, J.R.1    Schweer, H.2    Ikewaki, K.3    Stracke, H.4    Seyberth, H.J.5    Kaffarnik, H.6
  • 78
    • 74549148035 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
    • COI: 1:CAS:528:DC%2BC3cXntlKksg%3D%3D, PID: 19825813
    • Chapman MJ, Le Goff W, Guerin M, Kontush A. Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors. Eur Heart J. 2010;31:149–64.
    • (2010) Eur Heart J , vol.31 , pp. 149-164
    • Chapman, M.J.1    Le Goff, W.2    Guerin, M.3    Kontush, A.4
  • 79
    • 0036269506 scopus 로고    scopus 로고
    • Dose-dependent action of atorvastatin in type IIB hyperlipidemia: preferential and progressive reduction of atherogenic apoB-containing lipoprotein subclasses (VLDL-2, IDL, small dense LDL) and stimulation of cellular cholesterol efflux
    • COI: 1:CAS:528:DC%2BD38XktFOnsbo%3D, PID: 12052475
    • Guerin M, Egger P, Soudant C, Le Goff W, van Tol A, Dupuis R, et al. Dose-dependent action of atorvastatin in type IIB hyperlipidemia: preferential and progressive reduction of atherogenic apoB-containing lipoprotein subclasses (VLDL-2, IDL, small dense LDL) and stimulation of cellular cholesterol efflux. Atherosclerosis. 2002;163:287–96.
    • (2002) Atherosclerosis , vol.163 , pp. 287-296
    • Guerin, M.1    Egger, P.2    Soudant, C.3    Le Goff, W.4    van Tol, A.5    Dupuis, R.6
  • 80
    • 84939930221 scopus 로고    scopus 로고
    • Niesor EJ, Schwartz GG, Suchankova G, Benghozi R, Abt M, Kallend D. Statin decrease in transporter ABC A1 expression via miR33 induction may counteract cholesterol efflux by high-density lipoproteins raised with the cholesteryl ester transfer protein modulator dalcetrapib. Atherosclerosis. 2014; [In press]. In vitro models of cell culture show that statin treatment result in a reduction of ABCA1 expression via a statin-induced increase in miR33. This result seems to be confirmed because statin treatment reduces the effect of HDL on ABCA1-mediated cholesterol efflux. This finding might explain the lack of effect of HDL-raising therapies in patients already on statins
    • Niesor EJ, Schwartz GG, Suchankova G, Benghozi R, Abt M, Kallend D. Statin decrease in transporter ABC A1 expression via miR33 induction may counteract cholesterol efflux by high-density lipoproteins raised with the cholesteryl ester transfer protein modulator dalcetrapib. Atherosclerosis. 2014; [In press]. In vitro models of cell culture show that statin treatment result in a reduction of ABCA1 expression via a statin-induced increase in miR33. This result seems to be confirmed because statin treatment reduces the effect of HDL on ABCA1-mediated cholesterol efflux. This finding might explain the lack of effect of HDL-raising therapies in patients already on statins.
  • 82
    • 0023232216 scopus 로고
    • Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
    • COI: 1:STN:280:DyaL1c%2FjvFSjtw%3D%3D, PID: 3313041
    • Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med. 1987;317:1237–45.
    • (1987) N Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3    Heinonen, O.P.4    Heinsalmi, P.5    Helo, P.6
  • 83
    • 0026597808 scopus 로고
    • Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment
    • COI: 1:STN:280:DyaK38%2FpslamtQ%3D%3D, PID: 1728471
    • Manninen V, Tenkanen L, Koskinen P, Huttunen JK, Manttari M, Heinonen OP, et al. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment. Circulation. 1992;85:37–45.
    • (1992) Circulation , vol.85 , pp. 37-45
    • Manninen, V.1    Tenkanen, L.2    Koskinen, P.3    Huttunen, J.K.4    Manttari, M.5    Heinonen, O.P.6
  • 84
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • COI: 1:CAS:528:DyaK1MXltlyltbw%3D, PID: 10438259
    • Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med. 1999;341:410–8.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3    Fye, C.L.4    Anderson, J.W.5    Elam, M.B.6
  • 85
    • 0034604225 scopus 로고    scopus 로고
    • Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study. Circulation. 2000;102:21–7
    • Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study. Circulation. 2000;102:21–7.
  • 86
    • 64749095070 scopus 로고    scopus 로고
    • Effects of fenofibrate treatment on cardiovascular disease risk in 9795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
    • COI: 1:CAS:528:DC%2BD1MXjvVyqt7s%3D, PID: 18984774
    • Scott R, O'Brien R, Fulcher G, Pardy C, D'Emden M, Tse D, et al. Effects of fenofibrate treatment on cardiovascular disease risk in 9795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetes Care. 2009;32:493–8.
    • (2009) Diabetes Care , vol.32 , pp. 493-498
    • Scott, R.1    O'Brien, R.2    Fulcher, G.3    Pardy, C.4    D'Emden, M.5    Tse, D.6
  • 88
    • 77952708442 scopus 로고    scopus 로고
    • Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC3cXmsleksrc%3D, PID: 20462635
    • Jun M, Foote C, Lv J, Neal B, Patel A, Nicholls SJ, et al. Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis. Lancet. 2010;375:1875–84.
    • (2010) Lancet , vol.375 , pp. 1875-1884
    • Jun, M.1    Foote, C.2    Lv, J.3    Neal, B.4    Patel, A.5    Nicholls, S.J.6
  • 89
    • 62949223872 scopus 로고    scopus 로고
    • Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared with low- and high-dose simvastatin monotherapy
    • PID: 19332196, COI: 1:CAS:528:DC%2BD1MXjslyis7s%3D, e681–8
    • Airan-Javia SL, Wolf RL, Wolfe ML, Tadesse M, Mohler E, Reilly MP. Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared with low- and high-dose simvastatin monotherapy. Am Heart J. 2009;157:687. e681–8.
    • (2009) Am Heart J , vol.157 , pp. 687
    • Airan-Javia, S.L.1    Wolf, R.L.2    Wolfe, M.L.3    Tadesse, M.4    Mohler, E.5    Reilly, M.P.6
  • 90
    • 77953961808 scopus 로고    scopus 로고
    • Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib
    • COI: 1:CAS:528:DC%2BC3cXnsFGgu7w%3D, PID: 20448206
    • Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, et al. Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib. Arterioscler Thromb Vasc Biol. 2010;30:1430–8.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1430-1438
    • Yvan-Charvet, L.1    Kling, J.2    Pagler, T.3    Li, H.4    Hubbard, B.5    Fisher, T.6
  • 91
    • 84885844867 scopus 로고    scopus 로고
    • The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality
    • COI: 1:CAS:528:DC%2BC3sXhslaiu7zJ, PID: 23933538, The addition of niacin to statin therapy led to favorable changes in patients’ lipid profiles without a demonstrable effect on HDL functionality, thus, providing 1 potential mechanistic hypothesis for the disappointing results in recent clinical trials
    • Khera AV, Patel PJ, Reilly MP, Rader DJ. The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality. J Am Coll Cardiol. 2013;62:1909–10. The addition of niacin to statin therapy led to favorable changes in patients’ lipid profiles without a demonstrable effect on HDL functionality, thus, providing 1 potential mechanistic hypothesis for the disappointing results in recent clinical trials.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1909-1910
    • Khera, A.V.1    Patel, P.J.2    Reilly, M.P.3    Rader, D.J.4
  • 92
    • 77951483195 scopus 로고    scopus 로고
    • Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids
    • COI: 1:CAS:528:DC%2BC3cXkslKqsrk%3D, PID: 20167660
    • Wu BJ, Yan L, Charlton F, Witting P, Barter PJ, Rye KA. Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids. Arterioscler Thromb Vasc Biol. 2010;30:968–75.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 968-975
    • Wu, B.J.1    Yan, L.2    Charlton, F.3    Witting, P.4    Barter, P.J.5    Rye, K.A.6
  • 93
    • 0025104275 scopus 로고
    • Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation
    • COI: 1:STN:280:DyaK3M%2FhsFamtw%3D%3D, PID: 2215607
    • Inazu A, Brown ML, Hesler CB, Agellon LB, Koizumi J, Takata K, et al. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med. 1990;323:1234–8.
    • (1990) N Engl J Med , vol.323 , pp. 1234-1238
    • Inazu, A.1    Brown, M.L.2    Hesler, C.B.3    Agellon, L.B.4    Koizumi, J.5    Takata, K.6
  • 94
    • 1842815777 scopus 로고    scopus 로고
    • Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol
    • COI: 1:CAS:528:DC%2BD2cXjtVeqt7Y%3D, PID: 15071125
    • Brousseau ME, Schaefer EJ, Wolfe ML, Bloedon LT, Digenio AG, Clark RW, et al. Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med. 2004;350:1505–15.
    • (2004) N Engl J Med , vol.350 , pp. 1505-1515
    • Brousseau, M.E.1    Schaefer, E.J.2    Wolfe, M.L.3    Bloedon, L.T.4    Digenio, A.G.5    Clark, R.W.6
  • 95
    • 36348975228 scopus 로고    scopus 로고
    • Effects of torcetrapib in patients at high risk for coronary events
    • COI: 1:CAS:528:DC%2BD2sXhtlGns7bL, PID: 17984165
    • Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109–22.
    • (2007) N Engl J Med , vol.357 , pp. 2109-2122
    • Barter, P.J.1    Caulfield, M.2    Eriksson, M.3    Grundy, S.M.4    Kastelein, J.J.5    Komajda, M.6
  • 96
    • 34047106220 scopus 로고    scopus 로고
    • Effect of torcetrapib on the progression of coronary atherosclerosis
    • COI: 1:CAS:528:DC%2BD2sXjsFGnsrY%3D, PID: 17387129
    • Nissen SE, Tardif JC, Nicholls SJ, Revkin JH, Shear CL, Duggan WT, et al. Effect of torcetrapib on the progression of coronary atherosclerosis. N Engl J Med. 2007;356:1304–16.
    • (2007) N Engl J Med , vol.356 , pp. 1304-1316
    • Nissen, S.E.1    Tardif, J.C.2    Nicholls, S.J.3    Revkin, J.H.4    Shear, C.L.5    Duggan, W.T.6
  • 97
    • 34447265547 scopus 로고    scopus 로고
    • Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomized, double-blind trial
    • COI: 1:CAS:528:DC%2BD2sXns12jtLg%3D, PID: 17630038
    • Bots ML, Visseren FL, Evans GW, Riley WA, Revkin JH, Tegeler CH, et al. Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomized, double-blind trial. Lancet. 2007;370:153–60.
    • (2007) Lancet , vol.370 , pp. 153-160
    • Bots, M.L.1    Visseren, F.L.2    Evans, G.W.3    Riley, W.A.4    Revkin, J.H.5    Tegeler, C.H.6
  • 98
    • 34247241088 scopus 로고    scopus 로고
    • Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia
    • COI: 1:CAS:528:DC%2BD2sXksFCmsb4%3D, PID: 17387131
    • Kastelein JJ, van Leuven SI, Burgess L, Evans GW, Kuivenhoven JA, Barter PJ, et al. Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia. N Engl J Med. 2007;356:1620–30.
    • (2007) N Engl J Med , vol.356 , pp. 1620-1630
    • Kastelein, J.J.1    van Leuven, S.I.2    Burgess, L.3    Evans, G.W.4    Kuivenhoven, J.A.5    Barter, P.J.6
  • 99
    • 34247352806 scopus 로고    scopus 로고
    • Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL
    • COI: 1:CAS:528:DC%2BD2sXktFagtLs%3D, PID: 17322101
    • Yvan-Charvet L, Matsuura F, Wang N, Bamberger MJ, Nguyen T, Rinninger F, et al. Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL. Arterioscler Thromb Vasc Biol. 2007;27:1132–8.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1132-1138
    • Yvan-Charvet, L.1    Matsuura, F.2    Wang, N.3    Bamberger, M.J.4    Nguyen, T.5    Rinninger, F.6
  • 100
    • 84857034980 scopus 로고    scopus 로고
    • Functionality of postprandial larger HDL2 particles is enhanced following CETP inhibition therapy
    • COI: 1:CAS:528:DC%2BC38XjtVOgs7g%3D, PID: 22265126
    • Bellanger N, Julia Z, Villard EF, El Khoury P, Duchene E, Chapman MJ, et al. Functionality of postprandial larger HDL2 particles is enhanced following CETP inhibition therapy. Atherosclerosis. 2012;221:160–8.
    • (2012) Atherosclerosis , vol.221 , pp. 160-168
    • Bellanger, N.1    Julia, Z.2    Villard, E.F.3    El Khoury, P.4    Duchene, E.5    Chapman, M.J.6
  • 101
    • 0037035459 scopus 로고    scopus 로고
    • Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study
    • PID: 11994249, COI: 1:CAS:528:DC%2BD38XktlOku70%3D
    • de Grooth GJ, Kuivenhoven JA, Stalenhoef AF, de Graaf J, Zwinderman AH, Posma JL, et al. Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation. 2002;105:2159–65.
    • (2002) Circulation , vol.105 , pp. 2159-2165
    • de Grooth, G.J.1    Kuivenhoven, J.A.2    Stalenhoef, A.F.3    de Graaf, J.4    Zwinderman, A.H.5    Posma, J.L.6
  • 102
    • 80255122648 scopus 로고    scopus 로고
    • Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial
    • Fayad ZA, Mani V, Woodward M, Kallend D, Abt M, Burgess T, et al. Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial. Lancet. 2011;378:1547–59.
    • (2011) Lancet , vol.378 , pp. 1547-1559
    • Fayad, Z.A.1    Mani, V.2    Woodward, M.3    Kallend, D.4    Abt, M.5    Burgess, T.6
  • 103
    • 84859517252 scopus 로고    scopus 로고
    • Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial
    • PID: 22345126, COI: 1:CAS:528:DC%2BC38XlsFSktrc%3D
    • Luscher TF, Taddei S, Kaski JC, Jukema JW, Kallend D, Munzel T, et al. Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial. Eur Heart J. 2012;33:857–65.
    • (2012) Eur Heart J , vol.33 , pp. 857-865
    • Luscher, T.F.1    Taddei, S.2    Kaski, J.C.3    Jukema, J.W.4    Kallend, D.5    Munzel, T.6
  • 104
  • 105
    • 0019226420 scopus 로고
    • A-‘IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family
    • COI: 1:STN:280:DyaL3M%2Fkslaruw%3D%3D, PID: 7430351
    • Franceschini G, Sirtori CR, Capurso II A, Weisgraber KH, Mahley RW. A-‘IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family. J Clin Invest. 1980;66:892–900.
    • (1980) J Clin Invest , vol.66 , pp. 892-900
    • Franceschini, G.1    Sirtori, C.R.2    Capurso, A.3    Weisgraber, K.H.4    Mahley, R.W.5
  • 106
    • 0035901577 scopus 로고    scopus 로고
    • Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda study
    • COI: 1:CAS:528:DC%2BD3MXjslKksL8%3D, PID: 11306522
    • Sirtori CR, Calabresi L, Franceschini G, Baldassarre D, Amato M, Johansson J, et al. Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda study. Circulation. 2001;103:1949–54.
    • (2001) Circulation , vol.103 , pp. 1949-1954
    • Sirtori, C.R.1    Calabresi, L.2    Franceschini, G.3    Baldassarre, D.4    Amato, M.5    Johansson, J.6
  • 107
    • 0032478183 scopus 로고    scopus 로고
    • Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice
    • COI: 1:CAS:528:DyaK1cXhslCjtLg%3D, PID: 9498542
    • Shah PK, Nilsson J, Kaul S, Fishbein MC, Ageland H, Hamsten A, et al. Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice. Circulation. 1998;97:780–5.
    • (1998) Circulation , vol.97 , pp. 780-785
    • Shah, P.K.1    Nilsson, J.2    Kaul, S.3    Fishbein, M.C.4    Ageland, H.5    Hamsten, A.6
  • 108
    • 40649089928 scopus 로고    scopus 로고
    • Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: magnetic resonance imaging study in an experimental model of atherosclerosis
    • COI: 1:CAS:528:DC%2BD1cXjsVSmtrY%3D, PID: 18342230
    • Ibanez B, Vilahur G, Cimmino G, Speidl WS, Pinero A, Choi BG, et al. Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: magnetic resonance imaging study in an experimental model of atherosclerosis. J Am Coll Cardiol. 2008;51:1104–9.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1104-1109
    • Ibanez, B.1    Vilahur, G.2    Cimmino, G.3    Speidl, W.S.4    Pinero, A.5    Choi, B.G.6
  • 109
    • 0038012797 scopus 로고    scopus 로고
    • Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries
    • COI: 1:CAS:528:DC%2BD3sXjslehtb4%3D, PID: 12742990
    • Kaul S, Rukshin V, Santos R, Azarbal B, Bisgaier CL, Johansson J, et al. Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries. Circulation. 2003;107:2551–4.
    • (2003) Circulation , vol.107 , pp. 2551-2554
    • Kaul, S.1    Rukshin, V.2    Santos, R.3    Azarbal, B.4    Bisgaier, C.L.5    Johansson, J.6
  • 111
    • 4444249250 scopus 로고    scopus 로고
    • Rapid reversal of endothelial dysfunction in hypercholesterolemic apolipoprotein E-null mice by recombinant apolipoprotein A-I(Milano)-phospholipid complex
    • COI: 1:CAS:528:DC%2BD2cXnsFSlsb8%3D, PID: 15364338
    • Kaul S, Coin B, Hedayiti A, Yano J, Cercek B, Chyu KY, et al. Rapid reversal of endothelial dysfunction in hypercholesterolemic apolipoprotein E-null mice by recombinant apolipoprotein A-I(Milano)-phospholipid complex. J Am Coll Cardiol. 2004;44:1311–9.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1311-1319
    • Kaul, S.1    Coin, B.2    Hedayiti, A.3    Yano, J.4    Cercek, B.5    Chyu, K.Y.6
  • 112
    • 0242577955 scopus 로고    scopus 로고
    • Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial
    • COI: 1:CAS:528:DC%2BD3sXovVCjtbc%3D, PID: 14600188
    • Nissen SE, Tsunoda T, Tuzcu EM, Schoenhagen P, Cooper CJ, Yasin M, et al. Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. JAMA. 2003;290:2292–300.
    • (2003) JAMA , vol.290 , pp. 2292-2300
    • Nissen, S.E.1    Tsunoda, T.2    Tuzcu, E.M.3    Schoenhagen, P.4    Cooper, C.J.5    Yasin, M.6
  • 113
    • 32044448047 scopus 로고    scopus 로고
    • Relationship between atheroma regression and change in lumen size after infusion of apolipoprotein A-I Milano
    • COI: 1:CAS:528:DC%2BD28XitVaruro%3D, PID: 16516083
    • Nicholls SJ, Tuzcu EM, Sipahi I, Schoenhagen P, Crowe T, Kapadia S, et al. Relationship between atheroma regression and change in lumen size after infusion of apolipoprotein A-I Milano. J Am Coll Cardiol. 2006;47:992–7.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 992-997
    • Nicholls, S.J.1    Tuzcu, E.M.2    Sipahi, I.3    Schoenhagen, P.4    Crowe, T.5    Kapadia, S.6
  • 114
    • 0033543084 scopus 로고    scopus 로고
    • Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans
    • COI: 1:CAS:528:DyaK1MXlslyjsLo%3D, PID: 10441095
    • Eriksson M, Carlson LA, Miettinen TA, Angelin B. Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans. Circulation. 1999;100:594–8.
    • (1999) Circulation , vol.100 , pp. 594-598
    • Eriksson, M.1    Carlson, L.A.2    Miettinen, T.A.3    Angelin, B.4
  • 115
    • 34247397359 scopus 로고    scopus 로고
    • Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial
    • PID: 17387133
    • Tardif JC, Gregoire J, L'Allier PL, Ibrahim R, Lesperance J, Heinonen TM, et al. Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial. JAMA. 2007;297:1675–82.
    • (2007) JAMA , vol.297 , pp. 1675-1682
    • Tardif, J.C.1    Gregoire, J.2    L'Allier, P.L.3    Ibrahim, R.4    Lesperance, J.5    Heinonen, T.M.6
  • 116
    • 77953107241 scopus 로고    scopus 로고
    • A first-in-man, randomized, placebo-controlled study to evaluate the safety and feasibility of autologous delipidated high-density lipoprotein plasma infusions in patients with acute coronary syndrome
    • PID: 20538165
    • Waksman R, Torguson R, Kent KM, Pichard AD, Suddath WO, Satler LF, et al. A first-in-man, randomized, placebo-controlled study to evaluate the safety and feasibility of autologous delipidated high-density lipoprotein plasma infusions in patients with acute coronary syndrome. J Am Coll Cardiol. 2010;55:2727–35.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2727-2735
    • Waksman, R.1    Torguson, R.2    Kent, K.M.3    Pichard, A.D.4    Suddath, W.O.5    Satler, L.F.6
  • 117
    • 77952713824 scopus 로고    scopus 로고
    • RVX-208: a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo
    • COI: 1:CAS:528:DC%2BC3cXptV2msr0%3D, PID: 20513599
    • Bailey D, Jahagirdar R, Gordon A, Hafiane A, Campbell S, Chatur S, et al. RVX-208: a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo. J Am Coll Cardiol. 2010;55:2580–9.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2580-2589
    • Bailey, D.1    Jahagirdar, R.2    Gordon, A.3    Hafiane, A.4    Campbell, S.5    Chatur, S.6
  • 118
    • 79952005101 scopus 로고    scopus 로고
    • Efficacy and safety of a novel oral inducer of apolipoprotein a-I synthesis in statin-treated patients with stable coronary artery disease a randomized controlled trial
    • COI: 1:CAS:528:DC%2BC3MXkslWntLc%3D, PID: 21255957
    • Nicholls SJ, Gordon A, Johansson J, Wolski K, Ballantyne CM, Kastelein JJ, et al. Efficacy and safety of a novel oral inducer of apolipoprotein a-I synthesis in statin-treated patients with stable coronary artery disease a randomized controlled trial. J Am Coll Cardiol. 2011;57:1111–9.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 1111-1119
    • Nicholls, S.J.1    Gordon, A.2    Johansson, J.3    Wolski, K.4    Ballantyne, C.M.5    Kastelein, J.J.6
  • 119
    • 84939930223 scopus 로고    scopus 로고
    • Press release on November 4, 2013
    • http://www.resverlogix.com/media/press-release.html?id=494#.UxdhBvldWQc. Press release on November 4, 2013.
  • 120
    • 0035059743 scopus 로고    scopus 로고
    • A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis
    • COI: 1:CAS:528:DC%2BD3MXjtFSitbY%3D, PID: 11290826
    • Garber DW, Datta G, Chaddha M, Palgunachari MN, Hama SY, Navab M, et al. A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis. J Lipid Res. 2001;42:545–52.
    • (2001) J Lipid Res , vol.42 , pp. 545-552
    • Garber, D.W.1    Datta, G.2    Chaddha, M.3    Palgunachari, M.N.4    Hama, S.Y.5    Navab, M.6
  • 121
    • 0037154287 scopus 로고    scopus 로고
    • Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol
    • COI: 1:CAS:528:DC%2BD38XhsFSgt7k%3D, PID: 11804981
    • Navab M, Anantharamaiah GM, Hama S, Garber DW, Chaddha M, Hough G, et al. Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol. Circulation. 2002;105:290–2.
    • (2002) Circulation , vol.105 , pp. 290-292
    • Navab, M.1    Anantharamaiah, G.M.2    Hama, S.3    Garber, D.W.4    Chaddha, M.5    Hough, G.6
  • 122
    • 48549103014 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients
    • COI: 1:CAS:528:DC%2BD1cXmslWnu7w%3D, PID: 18323573
    • Bloedon LT, Dunbar R, Duffy D, Pinell-Salles P, Norris R, DeGroot BJ, et al. Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients. J Lipid Res. 2008;49:1344–52.
    • (2008) J Lipid Res , vol.49 , pp. 1344-1352
    • Bloedon, L.T.1    Dunbar, R.2    Duffy, D.3    Pinell-Salles, P.4    Norris, R.5    DeGroot, B.J.6


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