Limitation of serological testing for Lyme borreliosis: Evaluation of ELISA and Western blot in comparison with PCR and culture methods

Wiener Klinische Wochenschrift

Volumn 114, Issue 13-14, 2002, Pages 601-605

  Tylewska Wierzbanowska, Stanislawa ^a   Chmielewski, Tomasz ^a  

^a NATIONAL INSTITUTE OF HYGIENE   (Poland)

Author keywords

Borrelia burgdorferi cell line culture; Lyme borreliosis; Recombinant ELISA; Western blot

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ANTIBODY DETECTION; ARTICLE; BACTERIUM CULTURE; BACTERIUM DETECTION; CEREBROSPINAL FLUID; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INTERMETHOD COMPARISON; LYME DISEASE; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; SYNOVIAL FLUID; WESTERN BLOTTING; BLOOD; COMPARATIVE STUDY; ERYTHEMA CHRONICUM MIGRANS; EVALUATION; IMMUNOLOGY; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PREDICTION AND FORECASTING; QUALITY CONTROL; STANDARD;

BACTERIOLOGICAL TECHNIQUES; BLOTTING, WESTERN; COMPARATIVE STUDY; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHEMA CHRONICUM MIGRANS; HUMAN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LYME DISEASE; LYME NEUROBORRELIOSIS; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE OF TESTS; QUALITY CONTROL; HUMANS;

EID: 0037205676     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Sequestration of antibody to Borrelia burgdorferi immune complexes in seronegative Lyme disease
2. The isolation of Borrelia burgdorferi spirochetes from clinical material
3. Diversity of Borrelia burgdorferi sensu lato evidenced by restriction fragment lenght polimorphism of rrf(5S)-rrl(23S) intergenic spacer amplicons
4. Obecność przeciwcial dla Borrelia burgdorferi zwia̧zanych w kompleksy immunologiczne w surowicach leśników
5. Relationship between the Borrelia burgdorferi specific immune response and different stages and syndromes in neuroborreliosis
6. A limitation of 2-stage serological testing for Lyme disease: Enzyme immunoassay and immunoblot assay are not independent tests
7. IgM and IgG significant reactivity to Borrelia burgdorferi sensu stricto, Borrelia garinii and Borrelia afzelii among Italian patients affected by Lyme arthritis or neuroborreliosis
8. Recombinant chimeric Borrelia proteins for diagnosis of Lyme disease
9. Comparision of Western blot and enzyme-linked immunosorbent assay for diagnosis of Lyme borreliosis
10. Serum antibodies against Borrelia afzelii, Borrelia burgdorferi sensu stricto and the 41-kiloDalton flagellin in patients from a Lyme borreliosis endemic area: Analysis by EIA and immunoblot
11. Antibodies against whole sonicated Borrelia burgdorferi spirochetes, 41-kilodalton flagelin, and P39 protein in patients with PCR- or culture-proven late Lyme borreliosis