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Volumn 82, Issue , 2015, Pages 201-212

MiR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation

Author keywords

KLF4; MiR 200c; Proliferation; SUMOylation; Ubc9; VSMC

Indexed keywords

HISTONE DEACETYLASE 2; KRUPPEL LIKE FACTOR 4; MICRORNA 200C; NUCLEAR RECEPTOR COREPRESSOR; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN UBC9; COREPRESSOR PROTEIN; HISTONE DEMETHYLASE; KDM1A PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; MICRORNA; MIRN200 MICRORNA, HUMAN; PLATELET DERIVED GROWTH FACTOR B; PLATELET-DERIVED GROWTH FACTOR BB; PROTEIN BINDING; SERUM RESPONSE FACTOR; SRF PROTEIN, HUMAN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN-CONJUGATING ENZYME UBC9;

EID: 84925946723     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.03.011     Document Type: Article
Times cited : (31)

References (45)
  • 1
    • 58849152734 scopus 로고    scopus 로고
    • PIAS1 mediates TGFbeta-induced SM alpha-actin gene expression through inhibition of KLF4 function-expression by protein sumoylation
    • Kawai-Kowase K., Ohshima T., Matsui H., Tanaka T., Shimizu T., Iso T., et al. PIAS1 mediates TGFbeta-induced SM alpha-actin gene expression through inhibition of KLF4 function-expression by protein sumoylation. Arterioscler Thromb Vasc Biol 2009, 29:99-106.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 99-106
    • Kawai-Kowase, K.1    Ohshima, T.2    Matsui, H.3    Tanaka, T.4    Shimizu, T.5    Iso, T.6
  • 2
    • 36049046075 scopus 로고    scopus 로고
    • A novel cultured tissue model of rat aorta: VSMC proliferation mechanism in relationship to atherosclerosis
    • Wang C., Zhang Y., Yang Q., Yang Y., Gu Y., Wang M., et al. A novel cultured tissue model of rat aorta: VSMC proliferation mechanism in relationship to atherosclerosis. Exp Mol Pathol 2007, 83:453-458.
    • (2007) Exp Mol Pathol , vol.83 , pp. 453-458
    • Wang, C.1    Zhang, Y.2    Yang, Q.3    Yang, Y.4    Gu, Y.5    Wang, M.6
  • 3
    • 33646102903 scopus 로고    scopus 로고
    • Exposure to modeled microgravity induces metabolic idleness in malignant human MCF-7 and normal murine VSMC cells
    • Coinu R., Chiaviello A., Galleri G., Franconi F., Crescenzi E., Palumbo G. Exposure to modeled microgravity induces metabolic idleness in malignant human MCF-7 and normal murine VSMC cells. FEBS Lett 2006, 580:2465-2470.
    • (2006) FEBS Lett , vol.580 , pp. 2465-2470
    • Coinu, R.1    Chiaviello, A.2    Galleri, G.3    Franconi, F.4    Crescenzi, E.5    Palumbo, G.6
  • 4
    • 67349235964 scopus 로고    scopus 로고
    • Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms
    • Satoh K., Nigro P., Matoba T., O'Dell M.R., Cui Z., Shi X., et al. Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nat Med 2009, 15:649-656.
    • (2009) Nat Med , vol.15 , pp. 649-656
    • Satoh, K.1    Nigro, P.2    Matoba, T.3    O'Dell, M.R.4    Cui, Z.5    Shi, X.6
  • 5
    • 34548127794 scopus 로고    scopus 로고
    • Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells
    • Wassmann S., Wassmann K., Jung A., Velten M., Knuefermann P., Petoumenos V., et al. Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells. J Mol Cell Cardiol 2007, 43:301-307.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 301-307
    • Wassmann, S.1    Wassmann, K.2    Jung, A.3    Velten, M.4    Knuefermann, P.5    Petoumenos, V.6
  • 6
    • 84861866572 scopus 로고    scopus 로고
    • The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
    • Fabian M.R., Sonenberg N. The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol 2012, 19:586-593.
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 586-593
    • Fabian, M.R.1    Sonenberg, N.2
  • 7
    • 80051532504 scopus 로고    scopus 로고
    • Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4
    • Davis-Dusenbery B.N., Chan M.C., Reno K.E., Weisman A.S., Layne M.D., Lagna G., et al. Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. J Biol Chem 2011, 286:28097-28110.
    • (2011) J Biol Chem , vol.286 , pp. 28097-28110
    • Davis-Dusenbery, B.N.1    Chan, M.C.2    Reno, K.E.3    Weisman, A.S.4    Layne, M.D.5    Lagna, G.6
  • 8
    • 68049083397 scopus 로고    scopus 로고
    • MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation
    • Cheng Y., Liu X., Yang J., Lin Y., Xu D.Z., Lu Q., et al. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res 2009, 105:158-166.
    • (2009) Circ Res , vol.105 , pp. 158-166
    • Cheng, Y.1    Liu, X.2    Yang, J.3    Lin, Y.4    Xu, D.Z.5    Lu, Q.6
  • 9
    • 61949252089 scopus 로고    scopus 로고
    • A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia
    • Liu X., Cheng Y., Zhang S., Lin Y., Yang J., Zhang C. A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia. Circ Res 2009, 104:476-487.
    • (2009) Circ Res , vol.104 , pp. 476-487
    • Liu, X.1    Cheng, Y.2    Zhang, S.3    Lin, Y.4    Yang, J.5    Zhang, C.6
  • 10
    • 78650897480 scopus 로고    scopus 로고
    • MiR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation
    • Sun S.G., Zheng B., Han M., Fang X.M., Li H.X., Miao S.B., et al. miR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation. EMBO Rep 2011, 12:56-62.
    • (2011) EMBO Rep , vol.12 , pp. 56-62
    • Sun, S.G.1    Zheng, B.2    Han, M.3    Fang, X.M.4    Li, H.X.5    Miao, S.B.6
  • 11
    • 82755162967 scopus 로고    scopus 로고
    • MicroRNA-31 regulated by the extracellular regulated kinase is involved in vascular smooth muscle cell growth via large tumor suppressor homolog 2
    • Liu X., Cheng Y., Chen X., Yang J., Xu L., Zhang C. MicroRNA-31 regulated by the extracellular regulated kinase is involved in vascular smooth muscle cell growth via large tumor suppressor homolog 2. J Biol Chem 2011, 286:42371-42380.
    • (2011) J Biol Chem , vol.286 , pp. 42371-42380
    • Liu, X.1    Cheng, Y.2    Chen, X.3    Yang, J.4    Xu, L.5    Zhang, C.6
  • 12
    • 79960580410 scopus 로고    scopus 로고
    • Insulin promotes vascular smooth muscle cell proliferation via microRNA-208-mediated downregulation of p21
    • Zhang Y., Wang Y., Wang X., Eisner G.M., Asico L.D., Jose P.A., et al. Insulin promotes vascular smooth muscle cell proliferation via microRNA-208-mediated downregulation of p21. J Hypertens 2011, 29:1560-1568.
    • (2011) J Hypertens , vol.29 , pp. 1560-1568
    • Zhang, Y.1    Wang, Y.2    Wang, X.3    Eisner, G.M.4    Asico, L.D.5    Jose, P.A.6
  • 13
    • 84862806829 scopus 로고    scopus 로고
    • IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis
    • Rokavec M., Wu W., Luo J.L. IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis. Mol Cell 2012, 45:777-789.
    • (2012) Mol Cell , vol.45 , pp. 777-789
    • Rokavec, M.1    Wu, W.2    Luo, J.L.3
  • 14
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory P.A., Bert A.G., Paterson E.L., Barry S.C., Tsykin A., Farshid G., et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008, 10:593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3    Barry, S.C.4    Tsykin, A.5    Farshid, G.6
  • 15
    • 83655163681 scopus 로고    scopus 로고
    • Urokinase receptor associates with myocardin to control vascular smooth muscle cells phenotype in vascular disease
    • Kiyan Y., Limbourg A., Kiyan R., Tkachuk S., Limbourg F.P., Ovsianikov A., et al. Urokinase receptor associates with myocardin to control vascular smooth muscle cells phenotype in vascular disease. Arterioscler Thromb Vasc Biol 2012, 32:110-122.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 110-122
    • Kiyan, Y.1    Limbourg, A.2    Kiyan, R.3    Tkachuk, S.4    Limbourg, F.P.5    Ovsianikov, A.6
  • 16
    • 63449104333 scopus 로고    scopus 로고
    • MicroRNA-mediated regulation of Ubc9 expression in cancer cells
    • Wu F., Zhu S., Ding Y., Beck W.T., Mo Y.Y. MicroRNA-mediated regulation of Ubc9 expression in cancer cells. Clin Cancer Res 2009, 15:1550-1557.
    • (2009) Clin Cancer Res , vol.15 , pp. 1550-1557
    • Wu, F.1    Zhu, S.2    Ding, Y.3    Beck, W.T.4    Mo, Y.Y.5
  • 17
    • 34249046463 scopus 로고    scopus 로고
    • SUMOylation regulates kainate-receptor-mediated synaptic transmission
    • Martin S., Nishimune A., Mellor J.R., Henley J.M. SUMOylation regulates kainate-receptor-mediated synaptic transmission. Nature 2007, 447:321-325.
    • (2007) Nature , vol.447 , pp. 321-325
    • Martin, S.1    Nishimune, A.2    Mellor, J.R.3    Henley, J.M.4
  • 18
    • 44949181877 scopus 로고    scopus 로고
    • SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta
    • Oishi Y., Manabe I., Tobe K., Ohsugi M., Kubota T., Fujiu K., et al. SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta. Nat Med 2008, 14:656-666.
    • (2008) Nat Med , vol.14 , pp. 656-666
    • Oishi, Y.1    Manabe, I.2    Tobe, K.3    Ohsugi, M.4    Kubota, T.5    Fujiu, K.6
  • 19
    • 57649121591 scopus 로고    scopus 로고
    • SUMOylation regulates nuclear localization of Kruppel-like factor 5
    • Du J.X., Bialkowska A.B., McConnell B.B., Yang V.W. SUMOylation regulates nuclear localization of Kruppel-like factor 5. J Biol Chem 2008, 283:31991-32002.
    • (2008) J Biol Chem , vol.283 , pp. 31991-32002
    • Du, J.X.1    Bialkowska, A.B.2    McConnell, B.B.3    Yang, V.W.4
  • 20
    • 44449136860 scopus 로고    scopus 로고
    • Sumoylation and the function of CCAAT enhancer binding protein alpha (C/EBP alpha)
    • Khanna-Gupta A. Sumoylation and the function of CCAAT enhancer binding protein alpha (C/EBP alpha). Blood Cells Mol Dis 2008, 41:77-81.
    • (2008) Blood Cells Mol Dis , vol.41 , pp. 77-81
    • Khanna-Gupta, A.1
  • 21
    • 69149110152 scopus 로고    scopus 로고
    • Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
    • Papapetrou E.P., Tomishima M.J., Chambers S.M., Mica Y., Reed E., Menon J., et al. Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci U S A 2009, 106:12759-12764.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12759-12764
    • Papapetrou, E.P.1    Tomishima, M.J.2    Chambers, S.M.3    Mica, Y.4    Reed, E.5    Menon, J.6
  • 22
    • 84863072876 scopus 로고    scopus 로고
    • Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis
    • Gamper A.M., Qiao X., Kim J., Zhang L., DeSimone M.C., Rathmell W.K., et al. Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis. Mol Cell 2012, 45:233-243.
    • (2012) Mol Cell , vol.45 , pp. 233-243
    • Gamper, A.M.1    Qiao, X.2    Kim, J.3    Zhang, L.4    DeSimone, M.C.5    Rathmell, W.K.6
  • 23
    • 84863367020 scopus 로고    scopus 로고
    • TGF-beta1 downregulates AT1 receptor expression via PKC-delta-mediated Sp1 dissociation from KLF4 and Smad-mediated PPAR-gamma association with KLF4
    • Zhang X.H., Zheng B., Gu C., Fu J.R., Wen J.K. TGF-beta1 downregulates AT1 receptor expression via PKC-delta-mediated Sp1 dissociation from KLF4 and Smad-mediated PPAR-gamma association with KLF4. Arterioscler Thromb Vasc Biol 2012, 32:1015-1023.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1015-1023
    • Zhang, X.H.1    Zheng, B.2    Gu, C.3    Fu, J.R.4    Wen, J.K.5
  • 24
    • 78649698768 scopus 로고    scopus 로고
    • Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice
    • Tetreault M.P., Wang M.L., Yang Y., Travis J., Yu Q.C., Klein-Szanto A.J., et al. Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice. Gastroenterology 2010, 139:2124-2134.
    • (2010) Gastroenterology , vol.139 , pp. 2124-2134
    • Tetreault, M.P.1    Wang, M.L.2    Yang, Y.3    Travis, J.4    Yu, Q.C.5    Klein-Szanto, A.J.6
  • 25
    • 48249113711 scopus 로고    scopus 로고
    • Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury
    • Yoshida T., Kaestner K.H., Owens G.K. Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury. Circ Res 2008, 102:1548-1557.
    • (2008) Circ Res , vol.102 , pp. 1548-1557
    • Yoshida, T.1    Kaestner, K.H.2    Owens, G.K.3
  • 26
    • 69249123287 scopus 로고    scopus 로고
    • Kruppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells
    • Zheng B., Han M., Bernier M., Zhang X.H., Meng F., Miao S.B., et al. Kruppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells. J Biol Chem 2009, 284:22773-22785.
    • (2009) J Biol Chem , vol.284 , pp. 22773-22785
    • Zheng, B.1    Han, M.2    Bernier, M.3    Zhang, X.H.4    Meng, F.5    Miao, S.B.6
  • 27
    • 35448965633 scopus 로고    scopus 로고
    • Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro
    • Pidkovka N.A., Cherepanova O.A., Yoshida T., Alexander M.R., Deaton R.A., Thomas J.A., et al. Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro. Circ Res 2007, 101:792-801.
    • (2007) Circ Res , vol.101 , pp. 792-801
    • Pidkovka, N.A.1    Cherepanova, O.A.2    Yoshida, T.3    Alexander, M.R.4    Deaton, R.A.5    Thomas, J.A.6
  • 28
    • 79957507517 scopus 로고    scopus 로고
    • ATRA activates and PDGF-BB represses the SM22alpha promoter through KLF4 binding to, or dissociating from, its cis-DNA elements
    • Yu K., Zheng B., Han M., Wen J.K. ATRA activates and PDGF-BB represses the SM22alpha promoter through KLF4 binding to, or dissociating from, its cis-DNA elements. Cardiovasc Res 2011, 90:464-474.
    • (2011) Cardiovasc Res , vol.90 , pp. 464-474
    • Yu, K.1    Zheng, B.2    Han, M.3    Wen, J.K.4
  • 29
    • 84862874414 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic switching in atherosclerosis
    • Gomez D., Owens G.K. Smooth muscle cell phenotypic switching in atherosclerosis. Cardiovasc Res 2012, 95:156-164.
    • (2012) Cardiovasc Res , vol.95 , pp. 156-164
    • Gomez, D.1    Owens, G.K.2
  • 30
    • 84859488310 scopus 로고    scopus 로고
    • Retinoic acid receptor alpha mediates All-trans-retinoic acid-induced Klf4 gene expression by regulating Klf4 promoter activity in vascular smooth muscle cells
    • Shi J.H., Zheng B., Chen S., Ma G.Y., Wen J.K. Retinoic acid receptor alpha mediates All-trans-retinoic acid-induced Klf4 gene expression by regulating Klf4 promoter activity in vascular smooth muscle cells. J Biol Chem 2012, 287:10799-10811.
    • (2012) J Biol Chem , vol.287 , pp. 10799-10811
    • Shi, J.H.1    Zheng, B.2    Chen, S.3    Ma, G.Y.4    Wen, J.K.5
  • 31
    • 0037968290 scopus 로고    scopus 로고
    • Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes
    • Yoshida T., Sinha S., Dandre F., Wamhoff B.R., Hoofnagle M.H., Kremer B.E., et al. Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ Res 2003, 92:856-864.
    • (2003) Circ Res , vol.92 , pp. 856-864
    • Yoshida, T.1    Sinha, S.2    Dandre, F.3    Wamhoff, B.R.4    Hoofnagle, M.H.5    Kremer, B.E.6
  • 32
    • 31044442783 scopus 로고    scopus 로고
    • Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo
    • McDonald O.G., Wamhoff B.R., Hoofnagle M.H., Owens G.K. Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. J Clin Invest 2006, 116:36-48.
    • (2006) J Clin Invest , vol.116 , pp. 36-48
    • McDonald, O.G.1    Wamhoff, B.R.2    Hoofnagle, M.H.3    Owens, G.K.4
  • 33
    • 85171944301 scopus 로고    scopus 로고
    • MiR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis
    • Rebustiniv I.T., Hayashi T., Reynolds A.D., Dillard M.L., Carpenter E.M., Hoffman M.P. miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis. Development 2012, 139:20-191.
    • (2012) Development , vol.139 , pp. 20-191
    • Rebustiniv, I.T.1    Hayashi, T.2    Reynolds, A.D.3    Dillard, M.L.4    Carpenter, E.M.5    Hoffman, M.P.6
  • 34
    • 84868108584 scopus 로고    scopus 로고
    • MiR-200c inhibits melanoma progression and drug resistance through down-regulation of Bmi-1
    • Liu S., Tetzlaff M.T., Cui R., Xu X. miR-200c inhibits melanoma progression and drug resistance through down-regulation of Bmi-1. Am J Pathol 2012, 181:1823-1835.
    • (2012) Am J Pathol , vol.181 , pp. 1823-1835
    • Liu, S.1    Tetzlaff, M.T.2    Cui, R.3    Xu, X.4
  • 35
    • 84881551103 scopus 로고    scopus 로고
    • MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis
    • Hur K., Toiyama Y., Takahashi M., Balaguer F., Nagasaka T., Koike J., et al. MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut 2013, 62:1315-1326.
    • (2013) Gut , vol.62 , pp. 1315-1326
    • Hur, K.1    Toiyama, Y.2    Takahashi, M.3    Balaguer, F.4    Nagasaka, T.5    Koike, J.6
  • 36
    • 49649101156 scopus 로고    scopus 로고
    • Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells
    • Wei D., Kanai M., Jia Z., Le X., Xie K. Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. Cancer Res 2008, 68:4631-4639.
    • (2008) Cancer Res , vol.68 , pp. 4631-4639
    • Wei, D.1    Kanai, M.2    Jia, Z.3    Le, X.4    Xie, K.5
  • 37
    • 0034238112 scopus 로고    scopus 로고
    • Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif
    • Shie J.L., Chen Z.Y., Fu M., Pestell R.G., Tseng C.C. Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif. Nucleic Acids Res 2000, 28:2969-2976.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2969-2976
    • Shie, J.L.1    Chen, Z.Y.2    Fu, M.3    Pestell, R.G.4    Tseng, C.C.5
  • 38
    • 0037195422 scopus 로고    scopus 로고
    • Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells
    • Chen Z.Y., Shie J.L., Tseng C.C. Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells. J Biol Chem 2002, 277:46831-46839.
    • (2002) J Biol Chem , vol.277 , pp. 46831-46839
    • Chen, Z.Y.1    Shie, J.L.2    Tseng, C.C.3
  • 39
    • 80053149075 scopus 로고    scopus 로고
    • Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins
    • Qin Y., Xu J., Aysola K., Begum N., Reddy V., Chai Y., et al. Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins. J Cell Physiol 2011, 226:3355-3367.
    • (2011) J Cell Physiol , vol.226 , pp. 3355-3367
    • Qin, Y.1    Xu, J.2    Aysola, K.3    Begum, N.4    Reddy, V.5    Chai, Y.6
  • 40
    • 48849088676 scopus 로고    scopus 로고
    • Modulation of PLAGL2 transactivation activity by Ubc9 co-activation not SUMOylation
    • Guo Y., Yang M.C., Weissler J.C., Yang Y.S. Modulation of PLAGL2 transactivation activity by Ubc9 co-activation not SUMOylation. Biochem Biophys Res Commun 2008, 374:570-575.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 570-575
    • Guo, Y.1    Yang, M.C.2    Weissler, J.C.3    Yang, Y.S.4
  • 41
    • 0035826705 scopus 로고    scopus 로고
    • Ubc9 interacts with a nuclear localization signal and mediates nuclear localization of the paired-like homeobox protein Vsx-1 independent of SUMO-1 modification
    • Kurtzman A.L., Schechter N. Ubc9 interacts with a nuclear localization signal and mediates nuclear localization of the paired-like homeobox protein Vsx-1 independent of SUMO-1 modification. Proc Natl Acad Sci U S A 2001, 98:5602-5607.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5602-5607
    • Kurtzman, A.L.1    Schechter, N.2
  • 42
    • 48949094973 scopus 로고    scopus 로고
    • Modulation of transcription parameters in glucocorticoid receptor-mediated repression
    • Sun Y., Tao Y.G., Kagan B.L., He Y., Jr S.S. Modulation of transcription parameters in glucocorticoid receptor-mediated repression. Mol Cell Endocrinol 2008, 295:59-69.
    • (2008) Mol Cell Endocrinol , vol.295 , pp. 59-69
    • Sun, Y.1    Tao, Y.G.2    Kagan, B.L.3    He, Y.4    Jr, S.S.5
  • 43
    • 27644467440 scopus 로고    scopus 로고
    • Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
    • Sentis S., Le Romancer M., Bianchin C., Rostan M.C., Corbo L. Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity. Mol Endocrinol 2005, 19:2671-2684.
    • (2005) Mol Endocrinol , vol.19 , pp. 2671-2684
    • Sentis, S.1    Le Romancer, M.2    Bianchin, C.3    Rostan, M.C.4    Corbo, L.5
  • 44
    • 81155128125 scopus 로고    scopus 로고
    • GLUT4 and UBC9 protein expression is reduced inmuscle fromtype 2 diabetic patients with severe insulin resistance
    • Kampmann U., Christensen B., Nielsen T.S., Pedersen S.B., Orskov L., Lund S. GLUT4 and UBC9 protein expression is reduced inmuscle fromtype 2 diabetic patients with severe insulin resistance. PLoS One 2011, 6:e27854.
    • (2011) PLoS One , vol.6 , pp. e27854
    • Kampmann, U.1    Christensen, B.2    Nielsen, T.S.3    Pedersen, S.B.4    Orskov, L.5    Lund, S.6
  • 45
    • 77956237129 scopus 로고    scopus 로고
    • A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Kruppel-like factor 4
    • Du J.X., McConnell B.B., Yang V.W. A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Kruppel-like factor 4. J Biol Chem 2010, 285:28298-28308.
    • (2010) J Biol Chem , vol.285 , pp. 28298-28308
    • Du, J.X.1    McConnell, B.B.2    Yang, V.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.