Comparison of isorhamnetin absorption properties in total flavones of Hippophae rhamnoides L. with its pure form in a Caco-2 cell model mediated by multidrug resistance-associated protein

European Journal of Pharmaceutical Sciences

Volumn 73, Issue , 2015, Pages 1-8

  Xie, Yan ^a,b   Duan, Jingze ^a   Fu, Qingxue ^a   Xia, Mengxin ^a   Zhang, Lei ^a   Li, Guowen ^a   Wu, Tao ^a   Ji, Guang ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b LONGHUA HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Absorption; Caco 2 cells; Isorhamnetin; MRP2; TFH

Indexed keywords

BAICALEIN; CATECHIN; HYPACONITINE; ISORHAMNETIN; KAEMPFEROL; MESACONITINE; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; OSTHOLE; PACLITAXEL; PAEONIFLORIN; QUERCETIN; 3-METHYLQUERCETIN; FLAVONE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; PLANT EXTRACT;

ARTICLE; CACO 2 CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG TRANSPORT; HIPPOPHAE RHAMNOIDES; HUMAN; HUMAN CELL; MTT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEADY STATE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; EPITHELIUM; GENETICS; HIPPOPHAE; INTESTINE ABSORPTION; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; BLOTTING, WESTERN; CACO-2 CELLS; CELL SURVIVAL; EPITHELIUM; FLAVONES; HIPPOPHAE; HUMANS; INTESTINAL ABSORPTION; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEINS; PLANT EXTRACTS; QUERCETIN; RATS, SPRAGUE-DAWLEY;

EID: 84925945817     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.03.008     Document Type: Article

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