Body temperature, blood infection parameters, and outcome of thrombolysis-treated ischemic stroke patients

International Journal of Stroke

Volumn 8, Issue 8, 2013, Pages 632-638

  Tiainen, Marjaana ^a   Meretoja, Atte ^a,b   Strbian, Daniel ^a   Suvanto, Joel ^a   Curtze, Sami ^a   Lindsberg, Perttu J ^a,c   Soinne, Lauri ^a   Tatlisumak, Turgut ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Body temperature; C reactive protein; Ischemic stroke; Leukocytes; Outcome; Thrombolysis

Indexed keywords

C REACTIVE PROTEIN; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BLOODSTREAM INFECTION; BODY TEMPERATURE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; DISEASE ASSOCIATION; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; INFLAMMATION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANKIN SCALE;

BODY TEMPERATURE; C-REACTIVE PROTEIN; ISCHEMIC STROKE; LEUKOCYTES; OUTCOME; THROMBOLYSIS;

AGED; AGED, 80 AND OVER; BODY TEMPERATURE; C-REACTIVE PROTEIN; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INFLAMMATION; LEUKOCYTE COUNT; MALE; MIDDLE AGED; SEPSIS; STROKE; THROMBOLYTIC THERAPY; TREATMENT OUTCOME;

EID: 84888118455     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/ijs.12039     Document Type: Article

References (38)

1. Azzimondi G, Bassein L, Nonino F etal. Fever in acute stroke worsens prognosis. A prospective study. Stroke 1995; 26:2040-2043.
2. Grau AJ, Buggle F, Schnitzler P, Spiel M, Lichy C, Hacke W. Fever and infection early after ischemic stroke. J Neurol Sci 1999; 171:115-120.
3. Ginsberg MD, Busto R. Combating hyperthermia in acute stroke: a significant clinical concern. Stroke 1998; 29:529-534.
4. Hajat C, Hajat S, Sharma P. Effects of poststroke pyrexia on stroke outcome: a meta-analysis of studies in patients. Stroke 2000; 31:410-414.
5. van der Worp HB, Sena ES, Donnan GA, Howells DW, Macleod MR. Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis. Brain 2007; 130:3063-3074.
6. Wong AA, Davis JP, Schluter PJ, Henderson RD, O'Sullivan JD, Read SJ. The time course and determinants of temperature within the first 48h after ischaemic stroke. Cerebrovasc Dis 2007; 24:104-110.
7. Saini M, Saqqur M, Kamruzzaman A, Lees KR, Shuaib A, for VISTA Investigators. Effect of hyperthermia on prognosis after acute ischemic stroke. Stroke 2009; 40:3051-3059.
8. Adams HP Jr, del Zoppo G, Alberts MJ etal. Guidelines for the early management of adults with ischemic stroke. Stroke 2007; 38:1655-1711.
9. European Stroke Organisation (ESO). Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. Cerebrovasc Dis 2008; 25:457-507.
10. Jørgensen HS, Reith J, Nakayama H, Kammersgaard LP, Raaschou HO, Olsen TS. What determines good recovery in patients with the most severe strokes? The Copenhagen Stroke Study. Stroke 1999; 30:2008-2012.
11. Reith J, Jørgensen HS, Pedersen PM etal. Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome. Lancet 1996; 347:422-425.
12. Wang Y, Lim LL, Levi C, Heller RF, Fisher J. Influence of admission body temperature on stroke mortality. Stroke 2000; 31:404-409.
13. Boysen G, Christensen H. Stroke severity determines body temperature in acute stroke. Stroke 2001; 32:413-417.
14. den Hertog HM, van der Worp HB, van Gemert HM etal. An early rise in body temperature is related to unfavorable outcome after stroke: data from the PAIS study. J Neurol 2011; 258:302-307.
15. Ernon L, Schrooten M, Thijs V. Body temperature and outcome after stroke thrombolysis. Acta Neurol Scand 2006; 114:23-28.
16. Idicula TT, Waje-Andreassen U, Brogger J, Naess H, Lundstadsveen MT, Thomassen L. The effect of physiologic derangement in patients with stroke treated with thrombolysis. J Stroke Cerebrovasc Dis 2008; 17:141-146.
17. Millán M, Grau L, Castellanos M etal. Body temperature and response to thrombolytic therapy in acute ischaemic stroke. Eur J Neurol 2008; 15:1384-1389.
18. Naess H, Idicula T, Lagallo N, Brogger J, Waje-Andreassen U, Thomassen L. Inverse relationship of baseline body temperature and outcome between ischemic stroke patients treated and not treated with thrombolysis: the Bergen stroke study. Acta Neurol Scand 2010; 122:414-417.
19. Emsley HC, Hopkins SJ. Acute ischaemic stroke and infection: recent and emerging concepts. Lancet Neurol 2008; 7:341-353.
20. Macrez R, Ali C, Toutirais O etal. Stroke and the immune system: from pathophysiology to new therapeutic strategies. Lancet Neurol 2011; 10:471-480.
21. Strbian D, Karjalainen-Lindsberg ML, Kovanen PT, Tatlisumak T, Lindsberg PJ. Mast cell stabilization reduces hemorrhage formation and mortality after administration of thrombolytics in experimental ischemic stroke. Circulation 2007; 116:411-418.
22. Meretoja A, Putaala J, Tatlisumak T etal. Off-label thrombolysis is not associated with poor outcome in patients with stroke. Stroke 2010; 41:1450-1458.
23. Sund-Levander M, Forsberg C, Wahren LK. Normal oral, rectal, tympanic and axillary body temperature in adult men and women: a systematic literature review. Scand J Caring Sci 2002; 16:122-128.
24. Hacke W, Kaste M, Fieschi C etal. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet 1998; 352:1245-1251.
25. Strbian D, Sairanen T, Meretoja A etal. Patient outcomes from symptomatic intracerebral hemorrhage after stroke thrombolysis. Neurology 2011; 77:341-348.
26. Strbian D, Meretoja A, Ahlhelm FJ etal. Predicting outcome of IV thrombolysis-treated ischemic stroke patients: the DRAGON score. Neurology 2012; 78:427-432.
27. Strbian D, Engelter S, Michel P etal. Symptomatic intracranial hemorrhage after stroke thrombolysis: the SEDAN score. Ann Neurol 2012; 71:634-641.
28. Castillo J, Davalos A, Marrugat J, Noya M. Timing for fever-related brain damage in acute ischemic stroke. Stroke 1998; 29:2455-2460.
29. Audebert HJ, Rott MM, Eck T, Haberl RL. Systemic inflammatory response depends on initial stroke severity but is attenuated by successful thrombolysis. Stroke 2004; 35:2128-2133.
30. Lees JS, Mishra NK, Saini M, Lyden PD, Shuaib A, on behalf of the Virtual International Stroke Trials Archive (VISTA) Collaborators. Low body temperature does not compromise the treatment effect of alteplase. Stroke 2011; 42:2618-2621.
31. den Hertog HM, van Rossum JA, van der Worp HB etal. C-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death. J Neurol 2009; 256:2003-2008.
32. Kammersgaard LP, Jørgensen HS, Nakayama H, Reith J, Raaschou HO, Olsen TS. Leukocytosis in acute stroke: relation to initial stroke severity, infarct size, and outcome: the Copenhagen Stroke Study. J Stroke Cerebrovasc Dis 1999; 8:259-263.
33. Elkind MS, Sciacca RR, Boden-Albala B etal. Leukocyte count is associated with reduced endothelial reactivity. Atherosclerosis 2005; 181:329-338.
34. Grau AJ, Urbanek C, Palm F. Common infections and the risk of stroke. Nat Rev Neurol 2010; 6:681-694.
35. Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nat Med 2011; 17:796-808.
36. Worthmann H, Tryc AB, Deb M etal. Linking infection and inflammation in acute ischemic stroke. Ann N Y Acad Sci 2010; 1207:116-122.
37. Cermak J, Key NS, Bach RR, Balla J, Jacob HS, Vercellotti GM. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood 1993; 82:513-520.
38. Baron A, Montagne A, Cassé F etal. NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Cell Death Differ 2010; 17:860-871.