-
1
-
-
84857381128
-
Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents
-
Wong, K.F.; Yuan, Y.; Luk, J.M. Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents. Clin. Exp. Pharmacol. Physiol. 2012, 39, 311-320.
-
(2012)
Clin. Exp. Pharmacol. Physiol
, vol.39
, pp. 311-320
-
-
Wong, K.F.1
Yuan, Y.2
Luk, J.M.3
-
2
-
-
79951853010
-
Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer
-
Kannaiyan, R.; Shanmugam, M.K.; Sethi, G. Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer. Cancer Lett. 2011, 303, 9-20.
-
(2011)
Cancer Lett
, vol.303
, pp. 9-20
-
-
Kannaiyan, R.1
Shanmugam, M.K.2
Sethi, G.3
-
3
-
-
84862676391
-
Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthitis by modulating osteoimmune cross-talk
-
Nanjundaiah, S.M.; Venkatesha, S.H.; Yu, H.; Tong, L.; Stains, J.P.; Moudgil, K.D. Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthitis by modulating osteoimmune cross-talk. J. Biol. Chem. 2012, 287, 22216-22226.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 22216-22226
-
-
Nanjundaiah, S.M.1
Venkatesha, S.H.2
Yu, H.3
Tong, L.4
Stains, J.P.5
Moudgil, K.D.6
-
4
-
-
79955424712
-
Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses
-
Venkatesha, S.H.; Yu, H.; Rajaiah, R.; Tong, L.; Moudgil, K.D. Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses. J. Biol. Chem. 2011, 286, 15138-15146.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 15138-15146
-
-
Venkatesha, S.H.1
Yu, H.2
Rajaiah, R.3
Tong, L.4
Moudgil, K.D.5
-
5
-
-
84879184415
-
Celastrol prevents atherosclerosis via inhibiting lox-1 and oxidative stress
-
Gu, L.; Bai, W.; Li, S.; Zhang, Y.; Han, Y.; Gu, Y.; Meng, G.; Xie, L.; Wang, J.; Xiao, Y.; et al. Celastrol prevents atherosclerosis via inhibiting lox-1 and oxidative stress. PLoS One 2013, 8, e65477.
-
(2013)
PLoS One
, vol.8
-
-
Gu, L.1
Bai, W.2
Li, S.3
Zhang, Y.4
Han, Y.5
Gu, Y.6
Meng, G.7
Xie, L.8
Wang, J.9
Xiao, Y.10
-
6
-
-
77950377674
-
Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease
-
Paris, D.; Ganey, N.J.; Laporte, V.; Patel, N.S.; Beaulieu-Abdelahad, D.; Bachmeier, C.; March, A.; Ait-Ghezala, G.; Mullan, M.J. Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease. J. Neuroinflamm. 2010, 7, 17.
-
(2010)
J. Neuroinflamm
, vol.7
, pp. 17
-
-
Paris, D.1
Ganey, N.J.2
Laporte, V.3
Patel, N.S.4
Beaulieu-Abdelahad, D.5
Bachmeier, C.6
March, A.7
Ait-Ghezala, G.8
Mullan, M.J.9
-
7
-
-
0034752311
-
Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease
-
Allison, A.C.; Cacabelos, R.; Lombardi, V.R.; Alvarez, X.A.; Vigo, C. Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease. Prog. Neuropsychopharmacol. Biol. Psychiatry 2001, 25, 1341-1357.
-
(2001)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.25
, pp. 1341-1357
-
-
Allison, A.C.1
Cacabelos, R.2
Lombardi, V.R.3
Alvarez, X.A.4
Vigo, C.5
-
8
-
-
65549142792
-
Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model
-
Kim, D.Y.; Park, J.W.; Jeoung, D.; Ro, J.Y. Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model. Eur. J. Pharmacol. 2009, 612, 98-105.
-
(2009)
Eur. J. Pharmacol
, vol.612
, pp. 98-105
-
-
Kim, D.Y.1
Park, J.W.2
Jeoung, D.3
Ro, J.Y.4
-
9
-
-
0037379509
-
Observation on serum anti-double stranded DNA antibodies of tripterine in systemic lupus erythematosus of (NZBxW)F1 mice
-
Xu, X.; Wu, Z.; Xu, C.; Ren, Y.; Ge, Y. Observation on serum anti-double stranded DNA antibodies of tripterine in systemic lupus erythematosus of (NZBxW)F1 mice. Ann. Rheum. Dis. 2003, 62, 377-378.
-
(2003)
Ann. Rheum. Dis
, vol.62
, pp. 377-378
-
-
Xu, X.1
Wu, Z.2
Xu, C.3
Ren, Y.4
Ge, Y.5
-
10
-
-
84862077780
-
"Redundancy" of endocannabinoid inactivation: New challenges and opportunities for pain control
-
Piscitelli, F.; di Marzo, V. "Redundancy" of endocannabinoid inactivation: New challenges and opportunities for pain control. ACS Chem. Neurosci. 2012, 3, 356-363.
-
(2012)
ACS Chem. Neurosci
, vol.3
, pp. 356-363
-
-
Piscitelli, F.1
di Marzo, V.2
-
11
-
-
65449146377
-
Emerging strategies for exploiting cannabinoid receptor agonists as medicines
-
Pertwee, R.G. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br. J. Pharmacol. 2009, 156, 397-411.
-
(2009)
Br. J. Pharmacol
, vol.156
, pp. 397-411
-
-
Pertwee, R.G.1
-
12
-
-
80053501638
-
The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation
-
Alvarez-Jaimes, L.J.; Palmer, J.A. The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation. Curr. Pharm. Biotechnol. 2011, 12, 1644-1659.
-
(2011)
Curr. Pharm. Biotechnol
, vol.12
, pp. 1644-1659
-
-
Alvarez-Jaimes, L.J.1
Palmer, J.A.2
-
13
-
-
0038692066
-
Cannabis and the brain
-
Iversen, L. Cannabis and the brain. Brain 2003, 126, 1252-1270.
-
(2003)
Brain
, vol.126
, pp. 1252-1270
-
-
Iversen, L.1
-
14
-
-
0035150352
-
Cannabinoid receptors and pain
-
Pertwee, R.G. Cannabinoid receptors and pain. Prog. Neurobiol. 2001, 63, 569-611.
-
(2001)
Prog. Neurobiol
, vol.63
, pp. 569-611
-
-
Pertwee, R.G.1
-
15
-
-
61649089261
-
Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: Focus on anxiety and depression
-
Moreira, F.A.; Grieb, M.; Lutz, B. Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: Focus on anxiety and depression. Best Pract. Res. Clin. Endocrinol. Metab. 2009, 23, 133-144.
-
(2009)
Best Pract. Res. Clin. Endocrinol. Metab
, vol.23
, pp. 133-144
-
-
Moreira, F.A.1
Grieb, M.2
Lutz, B.3
-
16
-
-
0036019404
-
Endocannabinoids and pain: Spinal and peripheral analgesia in inflammation and neuropathy
-
Rice, A.S.; Farquhar-Smith, W.P.; Nagy, I. Endocannabinoids and pain: Spinal and peripheral analgesia in inflammation and neuropathy. Prostaglandins Leukot. Essent. Fat. Acids 2002, 66, 243-256.
-
(2002)
Prostaglandins Leukot. Essent. Fat. Acids
, vol.66
, pp. 243-256
-
-
Rice, A.S.1
Farquhar-Smith, W.P.2
Nagy, I.3
-
17
-
-
20144388149
-
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
-
Valenzano, K.J.; Tafesse, L.; Lee, G.; Harrison, J.E.; Boulet, J.M.; Gottshall, S.L.; Mark, L.; Pearson, M.S.; Miller, W.; Shan, S.; et al. Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. Neuropharmacology 2005, 48, 658-672.
-
(2005)
Neuropharmacology
, vol.48
, pp. 658-672
-
-
Valenzano, K.J.1
Tafesse, L.2
Lee, G.3
Harrison, J.E.4
Boulet, J.M.5
Gottshall, S.L.6
Mark, L.7
Pearson, M.S.8
Miller, W.9
Shan, S.10
-
18
-
-
0041836218
-
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
-
Ibrahim, M.M.; Deng, H.; Zvonok, A.; Cockayne, D.A.; Kwan, J.; Mata, H.P.; Vanderah, T.W.; Lai, J.; Porreca, F.; Makriyannis, A.; et al. Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS. Proc. Natl. Acad. Sci. USA 2003, 100, 10529-10533.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10529-10533
-
-
Ibrahim, M.M.1
Deng, H.2
Zvonok, A.3
Cockayne, D.A.4
Kwan, J.5
Mata, H.P.6
Vanderah, T.W.7
Lai, J.8
Porreca, F.9
Makriyannis, A.10
-
19
-
-
84878041885
-
The monoacylglycerol lipase inhibitor JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: Differential mechanisms of action
-
Kerr, D.M.; Harhen, B.; Okine, B.N.; Egan, L.J.; Finn, D.P.; Roche, M. The monoacylglycerol lipase inhibitor JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: Differential mechanisms of action. Br. J. Pharmacol. 2013, 169, 808-819.
-
(2013)
Br. J. Pharmacol
, vol.169
, pp. 808-819
-
-
Kerr, D.M.1
Harhen, B.2
Okine, B.N.3
Egan, L.J.4
Finn, D.P.5
Roche, M.6
-
20
-
-
84874649914
-
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model
-
Ghosh, S.; Wise, L.E.; Chen, Y.; Gujjar, R.; Mahadevan, A.; Cravatt, B.F.; Lichtman, A.H. The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. Life Sci. 2013, 92, 498-505.
-
(2013)
Life Sci
, vol.92
, pp. 498-505
-
-
Ghosh, S.1
Wise, L.E.2
Chen, Y.3
Gujjar, R.4
Mahadevan, A.5
Cravatt, B.F.6
Lichtman, A.H.7
-
21
-
-
33947324836
-
Inhibitors of monoacylglycerol lipase as novel analgesics
-
Hohmann, A.G. Inhibitors of monoacylglycerol lipase as novel analgesics. Br. J. Pharmacol. 2007, 150, 673-675.
-
(2007)
Br. J. Pharmacol
, vol.150
, pp. 673-675
-
-
Hohmann, A.G.1
-
22
-
-
84888374479
-
Identification of CB1/CB2 ligands from
-
Dossou, K.S.; Devkota, K.P.; Morton, C.; Egan, J.M.; Lu, G.; Beutler, J.A.; Moaddel, R. Identification of CB1/CB2 ligands from Zanthoxylum bungeanum. J. Nat. Prod. 2013, 76, 2060-2064.
-
(2013)
Zanthoxylum bungeanum. J. Nat. Prod
, vol.76
, pp. 2060-2064
-
-
Dossou, K.S.1
Devkota, K.P.2
Morton, C.3
Egan, J.M.4
Lu, G.5
Beutler, J.A.6
Moaddel, R.7
-
23
-
-
48249115990
-
β-Caryophyllene is a dietary cannabinoid
-
Gertsch, J.; Leonti, M.; Raduner, S.; Racz, I.; Chen, J.Z.; Xie, X.Q.; Altmann, K.H.; Karsak, M.; Zimmer, A. β-Caryophyllene is a dietary cannabinoid. Proc. Natl. Acad. Sci. USA 2008, 105, 9099-9104.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 9099-9104
-
-
Gertsch, J.1
Leonti, M.2
Raduner, S.3
Racz, I.4
Chen, J.Z.5
Xie, X.Q.6
Altmann, K.H.7
Karsak, M.8
Zimmer, A.9
-
24
-
-
71149108705
-
Discovery of potent and reversible monoacylglycerol lipase inhibitors
-
King, A.R.; Dotsey, E.Y.; Lodola, A.; Jung, K.M.; Ghomian, A.; Qiu, Y.; Fu, J.; Mor, M.; Piomelli, D. Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem. Biol. 2009, 6, 1045-1052.
-
(2009)
Chem. Biol
, vol.6
, pp. 1045-1052
-
-
King, A.R.1
Dotsey, E.Y.2
Lodola, A.3
Jung, K.M.4
Ghomian, A.5
Qiu, Y.6
Fu, J.7
Mor, M.8
Piomelli, D.9
-
25
-
-
84863612439
-
Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system
-
Dutra, R.C.; Simao da Silva, K.A.; Bento, A.F.; Marcon, R.; Paszcuk, A.F.; Meotti, F.C.; Pianowski, L.F.; Calixto, J.B. Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system. Neuropharmacology 2012, 63, 593-605.
-
(2012)
Neuropharmacology
, vol.63
, pp. 593-605
-
-
Dutra, R.C.1
Simao da Silva, K.A.2
Bento, A.F.3
Marcon, R.4
Paszcuk, A.F.5
Meotti, F.C.6
Pianowski, L.F.7
Calixto, J.B.8
-
26
-
-
84868100084
-
Dynamic changes to the endocannabinoid system in models of chronic pain
-
Rani Sagar, D.; Burston, J.J.; Woodhams, S.G.; Chapman, V. Dynamic changes to the endocannabinoid system in models of chronic pain. Philos. Trans. R. Soc. Lond. B 2012, 367, 3300-3311.
-
(2012)
Philos. Trans. R. Soc. Lond. B
, vol.367
, pp. 3300-3311
-
-
Rani Sagar, D.1
Burston, J.J.2
Woodhams, S.G.3
Chapman, V.4
-
27
-
-
0142148212
-
Spared nerve injury model of neuropathic pain in the mouse: A behavioral and anatomic analysis
-
Shields, S.D.; Eckert, W.A., III; Basbaum, A.I. Spared nerve injury model of neuropathic pain in the mouse: A behavioral and anatomic analysis. J. Pain 2003, 4, 465-470.
-
(2003)
J. Pain
, vol.4
, pp. 465-470
-
-
Shields, S.D.1
Eckert III, W.A.2
Basbaum, A.I.3
-
28
-
-
84926117383
-
Cannabinoids for pain management
-
Thaler, A.; Gupta, A.; Cohen, S.P. Cannabinoids for pain management. Adv. Psychosom. Med. 2011, 30, 125-138.
-
(2011)
Adv. Psychosom. Med
, vol.30
, pp. 125-138
-
-
Thaler, A.1
Gupta, A.2
Cohen, S.P.3
-
29
-
-
70349333074
-
Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside
-
Rahn, E.J.; Hohmann, A.G. Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside. Neurotherapeutics 2009, 6, 713-737.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 713-737
-
-
Rahn, E.J.1
Hohmann, A.G.2
-
30
-
-
38049028807
-
Cannabinoids for the treatment of neuropathic pain: Clinical evidence
-
Ashton, J.C.; Milligan, E.D. Cannabinoids for the treatment of neuropathic pain: Clinical evidence. Curr. Opin. Investig. Drugs 2008, 9, 65-75.
-
(2008)
Curr. Opin. Investig. Drugs
, vol.9
, pp. 65-75
-
-
Ashton, J.C.1
Milligan, E.D.2
-
31
-
-
0035822343
-
Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review
-
Campbell, F.A.; Tramer, M.R.; Carroll, D.; Reynolds, D.J.; Moore, R.A.; McQuay, H.J. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. BMJ 2001, 323, 13-16.
-
(2001)
BMJ
, vol.323
, pp. 13-16
-
-
Campbell, F.A.1
Tramer, M.R.2
Carroll, D.3
Reynolds, D.J.4
Moore, R.A.5
McQuay, H.J.6
-
32
-
-
13444306159
-
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice
-
Cunha, T.M.; Verri, W.A., Jr.; Silva, J.S.; Poole, S.; Cunha, F.Q.; Ferreira, S.H. A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc. Natl. Acad. Sci. USA 2005, 102, 1755-1760.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1755-1760
-
-
Cunha, T.M.1
Verri Jr., W.A.2
Silva, J.S.3
Poole, S.4
Cunha, F.Q.5
Ferreira, S.H.6
-
33
-
-
38349119715
-
Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain
-
Guindon, J.; Hohmann, A.G. Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain. Br. J. Pharmacol. 2008, 153, 319-334.
-
(2008)
Br. J. Pharmacol
, vol.153
, pp. 319-334
-
-
Guindon, J.1
Hohmann, A.G.2
-
34
-
-
77955326429
-
Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment
-
Baron, R.; Binder, A.; Wasner, G. Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol. 2010, 9, 807-819.
-
(2010)
Lancet Neurol
, vol.9
, pp. 807-819
-
-
Baron, R.1
Binder, A.2
Wasner, G.3
-
35
-
-
33646054102
-
Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse
-
Bourquin, A.F.; Suveges, M.; Pertin, M.; Gilliard, N.; Sardy, S.; Davison, A.C.; Spahn, D.R.; Decosterd, I. Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse. Pain 2006, 122, 14. e11-14. e14.
-
(2006)
Pain
, vol.122
-
-
Bourquin, A.F.1
Suveges, M.2
Pertin, M.3
Gilliard, N.4
Sardy, S.5
Davison, A.C.6
Spahn, D.R.7
Decosterd, I.8
|