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Volumn 15, Issue 8, 2014, Pages 13637-13648

Celastrol attenuates inflammatory and neuropathic pain mediated by cannabinoid receptor type 2

Author keywords

Cannabinoid receptors; Celastrol; Inflammatory pain; Neuropathic pain

Indexed keywords

5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1, 3, 3 TRIMETHYLBICYCLO [2.2.1] HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; CANNABINOID 2 RECEPTOR; CARRAGEENAN; CELASTROL; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; RIMONABANT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ANALGESIC AGENT; BORNANE DERIVATIVE; PYRAZOLE DERIVATIVE; TRIPTERINE; TRITERPENE;

EID: 84925884782     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150813637     Document Type: Article
Times cited : (42)

References (35)
  • 1
    • 84857381128 scopus 로고    scopus 로고
    • Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents
    • Wong, K.F.; Yuan, Y.; Luk, J.M. Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents. Clin. Exp. Pharmacol. Physiol. 2012, 39, 311-320.
    • (2012) Clin. Exp. Pharmacol. Physiol , vol.39 , pp. 311-320
    • Wong, K.F.1    Yuan, Y.2    Luk, J.M.3
  • 2
    • 79951853010 scopus 로고    scopus 로고
    • Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer
    • Kannaiyan, R.; Shanmugam, M.K.; Sethi, G. Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer. Cancer Lett. 2011, 303, 9-20.
    • (2011) Cancer Lett , vol.303 , pp. 9-20
    • Kannaiyan, R.1    Shanmugam, M.K.2    Sethi, G.3
  • 3
    • 84862676391 scopus 로고    scopus 로고
    • Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthitis by modulating osteoimmune cross-talk
    • Nanjundaiah, S.M.; Venkatesha, S.H.; Yu, H.; Tong, L.; Stains, J.P.; Moudgil, K.D. Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthitis by modulating osteoimmune cross-talk. J. Biol. Chem. 2012, 287, 22216-22226.
    • (2012) J. Biol. Chem , vol.287 , pp. 22216-22226
    • Nanjundaiah, S.M.1    Venkatesha, S.H.2    Yu, H.3    Tong, L.4    Stains, J.P.5    Moudgil, K.D.6
  • 4
    • 79955424712 scopus 로고    scopus 로고
    • Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses
    • Venkatesha, S.H.; Yu, H.; Rajaiah, R.; Tong, L.; Moudgil, K.D. Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses. J. Biol. Chem. 2011, 286, 15138-15146.
    • (2011) J. Biol. Chem , vol.286 , pp. 15138-15146
    • Venkatesha, S.H.1    Yu, H.2    Rajaiah, R.3    Tong, L.4    Moudgil, K.D.5
  • 8
    • 65549142792 scopus 로고    scopus 로고
    • Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model
    • Kim, D.Y.; Park, J.W.; Jeoung, D.; Ro, J.Y. Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model. Eur. J. Pharmacol. 2009, 612, 98-105.
    • (2009) Eur. J. Pharmacol , vol.612 , pp. 98-105
    • Kim, D.Y.1    Park, J.W.2    Jeoung, D.3    Ro, J.Y.4
  • 9
    • 0037379509 scopus 로고    scopus 로고
    • Observation on serum anti-double stranded DNA antibodies of tripterine in systemic lupus erythematosus of (NZBxW)F1 mice
    • Xu, X.; Wu, Z.; Xu, C.; Ren, Y.; Ge, Y. Observation on serum anti-double stranded DNA antibodies of tripterine in systemic lupus erythematosus of (NZBxW)F1 mice. Ann. Rheum. Dis. 2003, 62, 377-378.
    • (2003) Ann. Rheum. Dis , vol.62 , pp. 377-378
    • Xu, X.1    Wu, Z.2    Xu, C.3    Ren, Y.4    Ge, Y.5
  • 10
    • 84862077780 scopus 로고    scopus 로고
    • "Redundancy" of endocannabinoid inactivation: New challenges and opportunities for pain control
    • Piscitelli, F.; di Marzo, V. "Redundancy" of endocannabinoid inactivation: New challenges and opportunities for pain control. ACS Chem. Neurosci. 2012, 3, 356-363.
    • (2012) ACS Chem. Neurosci , vol.3 , pp. 356-363
    • Piscitelli, F.1    di Marzo, V.2
  • 11
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee, R.G. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br. J. Pharmacol. 2009, 156, 397-411.
    • (2009) Br. J. Pharmacol , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 12
    • 80053501638 scopus 로고    scopus 로고
    • The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation
    • Alvarez-Jaimes, L.J.; Palmer, J.A. The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation. Curr. Pharm. Biotechnol. 2011, 12, 1644-1659.
    • (2011) Curr. Pharm. Biotechnol , vol.12 , pp. 1644-1659
    • Alvarez-Jaimes, L.J.1    Palmer, J.A.2
  • 13
    • 0038692066 scopus 로고    scopus 로고
    • Cannabis and the brain
    • Iversen, L. Cannabis and the brain. Brain 2003, 126, 1252-1270.
    • (2003) Brain , vol.126 , pp. 1252-1270
    • Iversen, L.1
  • 14
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • Pertwee, R.G. Cannabinoid receptors and pain. Prog. Neurobiol. 2001, 63, 569-611.
    • (2001) Prog. Neurobiol , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 15
    • 61649089261 scopus 로고    scopus 로고
    • Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: Focus on anxiety and depression
    • Moreira, F.A.; Grieb, M.; Lutz, B. Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: Focus on anxiety and depression. Best Pract. Res. Clin. Endocrinol. Metab. 2009, 23, 133-144.
    • (2009) Best Pract. Res. Clin. Endocrinol. Metab , vol.23 , pp. 133-144
    • Moreira, F.A.1    Grieb, M.2    Lutz, B.3
  • 16
    • 0036019404 scopus 로고    scopus 로고
    • Endocannabinoids and pain: Spinal and peripheral analgesia in inflammation and neuropathy
    • Rice, A.S.; Farquhar-Smith, W.P.; Nagy, I. Endocannabinoids and pain: Spinal and peripheral analgesia in inflammation and neuropathy. Prostaglandins Leukot. Essent. Fat. Acids 2002, 66, 243-256.
    • (2002) Prostaglandins Leukot. Essent. Fat. Acids , vol.66 , pp. 243-256
    • Rice, A.S.1    Farquhar-Smith, W.P.2    Nagy, I.3
  • 17
    • 20144388149 scopus 로고    scopus 로고
    • Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
    • Valenzano, K.J.; Tafesse, L.; Lee, G.; Harrison, J.E.; Boulet, J.M.; Gottshall, S.L.; Mark, L.; Pearson, M.S.; Miller, W.; Shan, S.; et al. Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. Neuropharmacology 2005, 48, 658-672.
    • (2005) Neuropharmacology , vol.48 , pp. 658-672
    • Valenzano, K.J.1    Tafesse, L.2    Lee, G.3    Harrison, J.E.4    Boulet, J.M.5    Gottshall, S.L.6    Mark, L.7    Pearson, M.S.8    Miller, W.9    Shan, S.10
  • 19
    • 84878041885 scopus 로고    scopus 로고
    • The monoacylglycerol lipase inhibitor JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: Differential mechanisms of action
    • Kerr, D.M.; Harhen, B.; Okine, B.N.; Egan, L.J.; Finn, D.P.; Roche, M. The monoacylglycerol lipase inhibitor JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: Differential mechanisms of action. Br. J. Pharmacol. 2013, 169, 808-819.
    • (2013) Br. J. Pharmacol , vol.169 , pp. 808-819
    • Kerr, D.M.1    Harhen, B.2    Okine, B.N.3    Egan, L.J.4    Finn, D.P.5    Roche, M.6
  • 20
    • 84874649914 scopus 로고    scopus 로고
    • The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model
    • Ghosh, S.; Wise, L.E.; Chen, Y.; Gujjar, R.; Mahadevan, A.; Cravatt, B.F.; Lichtman, A.H. The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. Life Sci. 2013, 92, 498-505.
    • (2013) Life Sci , vol.92 , pp. 498-505
    • Ghosh, S.1    Wise, L.E.2    Chen, Y.3    Gujjar, R.4    Mahadevan, A.5    Cravatt, B.F.6    Lichtman, A.H.7
  • 21
    • 33947324836 scopus 로고    scopus 로고
    • Inhibitors of monoacylglycerol lipase as novel analgesics
    • Hohmann, A.G. Inhibitors of monoacylglycerol lipase as novel analgesics. Br. J. Pharmacol. 2007, 150, 673-675.
    • (2007) Br. J. Pharmacol , vol.150 , pp. 673-675
    • Hohmann, A.G.1
  • 25
    • 84863612439 scopus 로고    scopus 로고
    • Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system
    • Dutra, R.C.; Simao da Silva, K.A.; Bento, A.F.; Marcon, R.; Paszcuk, A.F.; Meotti, F.C.; Pianowski, L.F.; Calixto, J.B. Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system. Neuropharmacology 2012, 63, 593-605.
    • (2012) Neuropharmacology , vol.63 , pp. 593-605
    • Dutra, R.C.1    Simao da Silva, K.A.2    Bento, A.F.3    Marcon, R.4    Paszcuk, A.F.5    Meotti, F.C.6    Pianowski, L.F.7    Calixto, J.B.8
  • 27
    • 0142148212 scopus 로고    scopus 로고
    • Spared nerve injury model of neuropathic pain in the mouse: A behavioral and anatomic analysis
    • Shields, S.D.; Eckert, W.A., III; Basbaum, A.I. Spared nerve injury model of neuropathic pain in the mouse: A behavioral and anatomic analysis. J. Pain 2003, 4, 465-470.
    • (2003) J. Pain , vol.4 , pp. 465-470
    • Shields, S.D.1    Eckert III, W.A.2    Basbaum, A.I.3
  • 29
    • 70349333074 scopus 로고    scopus 로고
    • Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside
    • Rahn, E.J.; Hohmann, A.G. Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside. Neurotherapeutics 2009, 6, 713-737.
    • (2009) Neurotherapeutics , vol.6 , pp. 713-737
    • Rahn, E.J.1    Hohmann, A.G.2
  • 30
    • 38049028807 scopus 로고    scopus 로고
    • Cannabinoids for the treatment of neuropathic pain: Clinical evidence
    • Ashton, J.C.; Milligan, E.D. Cannabinoids for the treatment of neuropathic pain: Clinical evidence. Curr. Opin. Investig. Drugs 2008, 9, 65-75.
    • (2008) Curr. Opin. Investig. Drugs , vol.9 , pp. 65-75
    • Ashton, J.C.1    Milligan, E.D.2
  • 31
    • 0035822343 scopus 로고    scopus 로고
    • Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review
    • Campbell, F.A.; Tramer, M.R.; Carroll, D.; Reynolds, D.J.; Moore, R.A.; McQuay, H.J. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. BMJ 2001, 323, 13-16.
    • (2001) BMJ , vol.323 , pp. 13-16
    • Campbell, F.A.1    Tramer, M.R.2    Carroll, D.3    Reynolds, D.J.4    Moore, R.A.5    McQuay, H.J.6
  • 33
    • 38349119715 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain
    • Guindon, J.; Hohmann, A.G. Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain. Br. J. Pharmacol. 2008, 153, 319-334.
    • (2008) Br. J. Pharmacol , vol.153 , pp. 319-334
    • Guindon, J.1    Hohmann, A.G.2
  • 34
    • 77955326429 scopus 로고    scopus 로고
    • Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment
    • Baron, R.; Binder, A.; Wasner, G. Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol. 2010, 9, 807-819.
    • (2010) Lancet Neurol , vol.9 , pp. 807-819
    • Baron, R.1    Binder, A.2    Wasner, G.3
  • 35
    • 33646054102 scopus 로고    scopus 로고
    • Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse
    • Bourquin, A.F.; Suveges, M.; Pertin, M.; Gilliard, N.; Sardy, S.; Davison, A.C.; Spahn, D.R.; Decosterd, I. Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse. Pain 2006, 122, 14. e11-14. e14.
    • (2006) Pain , vol.122
    • Bourquin, A.F.1    Suveges, M.2    Pertin, M.3    Gilliard, N.4    Sardy, S.5    Davison, A.C.6    Spahn, D.R.7    Decosterd, I.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.