Irradiation-induced hippocampal neurogenesis impairment is associated with epigenetic regulation of bdnf gene transcription

Brain Research

Volumn 1577, Issue , 2014, Pages 77-88

  Ji, Shengjun ^a   Tian, Ye ^a   Lu, Yi ^b   Sun, Rui ^a   Ji, Jianfeng ^a   Zhang, Liyuan ^a   Duan, Shumin ^b  

^a THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

bdnf; Histone acetylation HDAC1; Neurogenesis; Whole brain irradiation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; HISTONE DEACETYLASE 1; TRICHOSTATIN A; HDAC1 PROTEIN, RAT; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN RADIATION; CELL PROLIFERATION; CELL SURVIVAL; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HISTONE ACETYLATION; IMMUNOFLUORESCENCE; LATENT PERIOD; MALE; MEMORY CONSOLIDATION; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RADIATION DOSE; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; STEM CELL; UPREGULATION; ANIMAL; COGNITION DISORDERS; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC EPIGENESIS; GENETICS; METABOLISM; NEURAL STEM CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; RADIATION RESPONSE; RANDOMIZATION;

RATTUS;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; COGNITION DISORDERS; EPIGENESIS, GENETIC; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; HISTONE DEACETYLASE 1; MALE; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; PROMOTER REGIONS, GENETIC; PROTEIN MODIFICATION, TRANSLATIONAL; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 84925883694     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.06.035     Document Type: Article

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