An experimental study of acute radiation-induced cognitive dysfunction in a young rat model

American Journal of Neuroradiology

Volumn 31, Issue 2, 2010, Pages 383-387

  Liu, Y ^a,b   Xiao, S ^a   Liu, Jun ^a   Zhou, H ^a   Liu, Z ^a   Xin, Y ^a   Suo, W Z ^c,d  

^a SUN YAT SEN UNIVERSITY   (China)

^b Tai'an Central Hospital   (China)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN RADIATION; BRAIN WATER; CANCER RADIOTHERAPY; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DETERIORATION; HISTOPATHOLOGY; MALE; NEUROPSYCHOLOGICAL TEST; NEURORADIOLOGY; NONHUMAN; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION RESPONSE; RAT; SPRAGUE DAWLEY RAT; WATER CONTENT;

ACUTE DISEASE; AGE FACTORS; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN DISEASES; COGNITION; COGNITION DISORDERS; COLORING AGENTS; DISEASE MODELS, ANIMAL; EVANS BLUE; MALE; MAZE LEARNING; RADIATION INJURIES; RATS; RATS, SPRAGUE-DAWLEY; WATER;

EID: 76749117160     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: 10.3174/ajnr.A1801     Document Type: Article

References (29)

1. Tsao MN, Lloyd NS, Wong RK, et al. Radiotherapeutic management of brain metastases: a systematic review and meta-analysis. Cancer Treat Rev 2005;31:256-73
2. Kantor G, Laprie A, Huchet A, et al. Radiation therapy for glial tumors: technical aspects and clinical indications. Cancer Radiother 2008;12:687-94
3. Coleman CN, Stone HB, Moulder JE, et al. Modulation of radiation injury. Science 2004;304:693-94
4. Yan L, Xi Z, Drettner B. Epidemiological studies of nasopharyngeal cancer in the Guangzhou area, China preliminary report. Acta Otolaryngol 1989;107:424-27
5. Li CC, Yu MC, Henderson BE. Some epidemiologic observations of nasopharyngeal carcinoma in Guangdong, People's Republic of China. Natl Cancer Inst Monogr 1985;69:49-52
6. Chang ET, Adami HO. The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 2006;15:1765-77
7. Langleben DD, Segall GM. PET in differentiation of recurrent brain tumor from radiation injury. J Nucl Med 2000;41:1861-67
8. Chong VF, Fan YF, Mukherji SK. Radiation-induced temporal lobe changes: CT and MR imaging characteristics. AJR Am J Roentgenol 2000;175:431-36
9. Roman DD, Sperduto PW. Neuropsychological effects of cranial radiation: current knowledge and future directions. Int J Radiat Oncol Biol Phys 1995;31:983-98
10. Welzel G, Fleckenstein K, Mai SK, et al. Acute neurocognitive impairment during cranial radiation therapy in patients with intracranial tumors. Strahlenther Onkol 2008;184:647-54
11. Crossen JR, Garwood D, Glatstein E, et al. Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy. J Clin Oncol 1994;12:627-42
12. Lamproglou I, Chen QM, Boisserie G, et al. Radiation-induced cognitive dysfunction: an experimental model in the old rat. Int J Radiat Oncol Biol Phys 1995;31:65-70
13. Morris RG, Garrud P, Rawlins JN, et al. Place navigation impaired in rats with hippocampal lesions. Nature 1982;297:681-83
14. Suo Z, Fang C, Crawford F, et al. Superoxide free radical and intracellular calcium mediate A beta(1- 42) induced endothelial toxicity. Brain Res 1997;762:144-52
15. Whalen MJ, Carlos TM, Wisniewski SR, et al. Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats. Crit Care Med 2000;28:3710-17
16. Johannesen TB, Lien HH, Hole KH, et al. Radiological and clinical assessment of long-term brain tumour survivors after radiotherapy. Radiother Oncol 2003;69:169-76
17. Serduc R, van de Looij Y, Francony G, et al. Characterization and quantification of cerebral edema induced by synchrotron x-ray microbeam radiation therapy. Phys Med Biol 2008;53:1153-66
18. Kobierska A, Karnicka-Młodkowska H, Solska E. [Radiotherapy of neoplasms of the central nervous system.] Neurol Neurochir Pol 1983;17:85-90
19. Yoneoka Y, Satoh M, Akiyama K, et al. An experimental study of radiationinduced cognitive dysfunction in an adult rat model. Br J Radiol 1999;72:1196-201
20. Hodges H, Katzung N, Sowinski P, et al. Late behavioural and neuropathological effects of local brain irradiation in the rat. Behav Brain Res 1998;91:99-114
21. Delattre JY, Shapiro WR, Ponsner JB. Acute effects of low-dose cranial irradiation on regional capillary permeability in experimental brain tumors. J Neurol Sci 1989;90:147-53
22. Chiang CS, McBride WH. Radiation enhances tumor necrosis factor alpha production by murine brain cells. Brain Res 1991;566:265-69
23. Hayakawa K, Borchardt PE, Sakuma S, et al. Microglial cytokine gene induction after irradiation is affected by morphologic differentiation. Radiat Med 1997;15:405-10
24. Shi L, Adams MM, Long A. Spatial learning and memory deficits after wholebrain irradiation are associated with changes in NMDA receptor subunits in the hippocampus. Radiation Res 2006;166:892-99
25. Madsen TM, Kristjansen PE, Bolwig TG, et al. Arrested neuronal proliferation and impaired hippocampal function following fractionated irradiation in the adult rat. Neuroscience 2003;119:635-42
26. St George EJ, Perks J, Plowman PN. Stereotactic radiosurgery XIV: The role of the haemosiderin 'ring' in the development of adverse reactions following radiosurgery for intracranial cavernous malformations: a sustainable hypothesis. Br J Neurosurg 2002;16:385-91
27. Diserbo M, Agin A, Lamproglou I, et al. Blood-brain barrier permeability after gamma whole-body irradiation: an in vivo microdialysis study. Can J Physiol Pharmacol 2002;80:670-78
28. Nakata H, Yoshimine T, Murasawa A, et al. Early blood-brain barrier disruption after high-dose single-fraction irradiation in rats. Acta Neurochir (Wien) 1995;136:82-86
29. Hopewell JW, Calvo W, Campling D. Effects of radiation on the microvasculature. Implications for normal-tissue damage. Front Radiat Ther Oncol 1989: 23:85-95