Compromised quality of life in adult patients who have received a radiation dose towards the basal part of the brain. A case-control study in long-term survivors from cancer in the head and neck region

Radiation Oncology

Volumn 7, Issue 1, 2012, Pages

  Löfdahl, Elisabet ^a   Berg, Gertrud ^a   Johansson, Karl Axel ^b   Zachrisson, Maria L ^c   Malmgren, Helge ^d   Mercke, Claes ^a   Olsson, Erik ^e   Wiren, Lena ^c   Johannsson, Gudmundur ^c  

^a Departments of Oncology   (Sweden)

^b Departments Radiation Physics   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d Linguistics and Theory of Science ^*  (Sweden)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

CNS; Growth hormone; Head and neck cancer; Long term survivors; Low dose radiation; Quality of life

Indexed keywords

ADULT; AGED; ANXIETY DISORDER; ARTICLE; CANCER SURVIVOR; CASE CONTROL STUDY; DEPRESSION; FEMALE; HEAD AND NECK CANCER; HUMAN; HUMAN TISSUE; HYPOPHYSIS; HYPOTHALAMUS; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; OROPHARYNX CANCER; PHYSICAL ACTIVITY; QUALITY OF LIFE; RADIATION DOSE;

ADULT; AGED; ANXIETY; ATTITUDE TO HEALTH; BRACHYTHERAPY; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; DEPRESSION; FOLLOW-UP STUDIES; HUMANS; HYPOTHALAMUS; IMAGING, THREE-DIMENSIONAL; LEISURE ACTIVITIES; LONGITUDINAL STUDIES; MIDDLE AGED; MOTOR ACTIVITY; OROPHARYNGEAL NEOPLASMS; PHARYNGEAL NEOPLASMS; PITUITARY GLAND; QUALITY OF LIFE; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, HIGH-ENERGY; SOMATOFORM DISORDERS; SURVIVORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84867902632     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-7-179     Document Type: Article

References (30)

1. Rosen T, Wiren L, Wilhelmsen L, Wiklund I, Bengtsson BA. Decreased psychological well-being in adult patients with growth hormone deficiency. Clin Endocrinol (Oxf) 1994, 40:111-116.
2. Salomon F, Cuneo RC, Hesp R, Sonksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 1989, 321:1797-1803. 10.1056/NEJM198912283212605, 2687691.
3. Wallymahmed ME, Foy P, Shaw D, Hutcheon R, Edwards RH, MacFarlane IA. Quality of life, body composition and muscle strength in adult growth hormone deficiency; the influence of growth hormone replacement therapy for up to 3 years. Clin Endocrinol (Oxf) 1997, 47:439-446.
4. Clayton PE, Shalet SM. Dose dependency of time of onset of radiation-induced growth hormone deficiency. J Pediatr 1991, 118:226-228. 10.1016/S0022-3476(05)80487-1, 1993949.
5. Constine LS, Woolf PD, Cann D, Mick G, McCormick K, Raubertas RF, Rubin P. Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med 1993, 328:87-94. 10.1056/NEJM199301143280203, 8416438.
6. Hall P, Adami HO, Trichopoulos D, Pedersen NL, Lagiou P, Ekbom A, Ingvar M, Lundell M, Granath F. Effect of low doses of ionising radiation in infancy on cognitive function in adulthood: Swedish population based cohort study. BMJ 2004, 328:19. 10.1136/bmj.328.7430.19, 313898, 14703539.
7. Hall EJ, Wuu CS. Radiation-induced second cancers: the impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys 2003, 56:83-88. 10.1016/S0360-3016(03)00073-7, 12694826.
8. Horiot JC. Interstitial brachytherapy in velo-tonsillar tumors: the ultimate boost. Int J Radiat Oncol Biol Phys 1995, 31:1021-1022. discussion 1023, 10.1016/0360-3016(94)00667-9, 7860376.
9. Abendstein H, Nordgren M, Boysen M, Jannert M, Silander E, Ahlner-Elmqvist M, Hammerlid E, Bjordal K. Quality of life and head and neck cancer: a 5 year prospective study. Laryngoscope 2005, 115:2183-2192. 10.1097/01.MLG.0000181507.69620.14, 16369164.
10. Hammerlid E, Taft C. Health-related quality of life in long-term head and neck cancer survivors: a comparison with general population norms. Br J Cancer 2001, 84:149-156. 10.1054/bjoc.2000.1576, 2363699, 11161369.
11. Nordgren M, Hammerlid E, Bjordal K, Ahlner-Elmqvist M, Boysen M, Jannert M. Quality of life in oral carcinoma: a 5-year prospective study. Head Neck 2008, 30:461-470. 10.1002/hed.20735, 18098303.
12. Pourel N, Peiffert D, Lartigau E, Desandes E, Luporsi E, Conroy T. Quality of life in long-term survivors of oropharynx carcinoma. Int J Radiat Oncol Biol Phys 2002, 54:742-751. 10.1016/S0360-3016(02)02959-0, 12377326.
13. Pernot M, Malissard L, Hoffstetter S, Luporsi E, Aletti P, Peiffert D, Allavena C, Kozminski P, Bey P. Influence of tumoral, radiobiological, and general factors on local control and survival of a series of 361 tumors of the velotonsillar area treated by exclusive irradiation (external beam irradiation+brachytherapy or brachytherapy alone). Int J Radiat Oncol Biol Phys 1994, 30:1051-1057. 10.1016/0360-3016(94)90309-3, 7961011.
14. Corvo R. Evidence-based radiation oncology in head and neck squamous cell carcinoma. Radiother Oncol 2007, 85:156-170. 10.1016/j.radonc.2007.04.002, 17482300.
15. Derogatis LR. Symptom Checklist-90 Revised 1994, National Computer systems Incorporated, Minneapolis.
16. Wiklund I. The Nottingham Health Profile-a measure of health-related quality of life. Scand J Prim Health Care Suppl 1990, 1:15-18.
17. Dupuy HJ. The Psychological General Well-Being (PGWB) Index. Book The Psychological General Well-Being (PGWB) Index 1984, 170-183. Le Jacq Publishing, New York.
18. Baecke JA, Burema J, Frijters JE. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr 1982, 36:936-942.
19. Tell R, Sjodin H, Lundell G, Lewin F, Lewensohn R. Hypothyroidism after external radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 1997, 39:303-308.
20. Tell R, Lundell G, Nilsson B, Sjodin H, Lewin F, Lewensohn R. Long-term incidence of hypothyroidism after radiotherapy in patients with head-and-neck cancer. Int J Radiat Oncol Biol Phys 2004, 60:395-400. 10.1016/j.ijrobp.2004.03.020, 15380571.
21. Link K, Moell C, Osterberg K, Persson R, Orbaek P, Garwicz S, Cavallin-Stahl E, Erfurth EM. Adult survivors of childhood acute lymphoblastic leukaemia with GH deficiency have normal self-rated quality of life but impaired neuropsychological performance 20 years after cranial irradiation. Clin Endocrinol (Oxf) 2006, 65:617-625.
22. Abayomi OK. Pathogenesis of cognitive decline following therapeutic irradiation for head and neck tumors. Acta Oncol 2002, 41:346-351. 10.1080/028418602760169389, 12234025.
23. Persani L, Ferretti E, Borgato S, Faglia G, Beck-Peccoz P. Circulating thyrotropin bioactivity in sporadic central hypothyroidism. J Clin Endocrinol Metab 2000, 85:3631-3635. 10.1210/jc.85.10.3631, 11061514.
24. Kramer C, von Muhlen D, Kritz-Silverstein D, Barrett-Connor E. Treated hypothyroidism, cognitive function, and depressed mood in old age: The Rancho Bernardo Study. Eur J Endocrinol 2009, 161:917-921. 10.1530/EJE-09-0606, 19755406.
25. Monje M. Cranial radiation therapy and damage to hippocampal neurogenesis. Dev Disabil Res Rev 2008, 14:238-242. 10.1002/ddrr.26, 18924155.
26. Petruson K, Mercke C, Lundberg LM, Silander E, Hammerlid E. Longitudinal evaluation of patients with cancer in the oral tongue, tonsils, or base of tongue-does interstitial radiation dose affect quality of life?. Brachytherapy 2005, 4:271-277. 10.1016/j.brachy.2005.06.001, 16344257.
27. Ringash J, Warde P, Lockwood G, O'Sullivan B, Waldron J, Cummings B. Postradiotherapy quality of life for head-and-neck cancer patients is independent of xerostomia. Int J Radiat Oncol Biol Phys 2005, 61:1403-1407. 10.1016/j.ijrobp.2004.08.001, 15817343.
28. Ringash J, Lockwood G, O'Sullivan B, Warde P, Bayley A, Cummings B, Kim J, Sellmann S, Waldron J. Hyperfractionated, accelerated radiotherapy for locally advanced head and neck cancer: quality of life in a prospective phase I/II trial. Radiother Oncol 2008, 87:181-187. 10.1016/j.radonc.2007.12.028, 18215435.
29. Foley KL, Farmer DF, Petronis VM, Smith RG, McGraw S, Smith K, Carver CS, Avis N. A qualitative exploration of the cancer experience among long-term survivors: comparisons by cancer type, ethnicity, gender, and age. Psychooncology 2006, 15:248-258. 10.1002/pon.942, 15940742.
30. Rosenthal DI, Blanco AI. Head and neck squamous cell carcinoma: optimizing the therapeutic index. Expert Rev Anticancer Ther 2005, 5:501-514. 10.1586/14737140.5.3.501, 16001957.