Evidence for Involvement of Spinal RANTES in the Antinociceptive Effects of Triptolide, a Diterpene Triepoxide, in a Rat Model of Bone Cancer Pain

Basic and Clinical Pharmacology and Toxicology

Volumn 115, Issue 6, 2014, Pages 477-480

  Hang, Li Hua ^a   Li, Shu Na ^a   Shao, Dong Hua ^a   Chen, Zheng ^a   Chen, Yuan Feng ^a   Shu, Wei Wei ^a  

^a AFFILIATED PEOPLE S HOSPITAL OF JIANGSU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RANTES; TRIPTOLIDE; ANALGESIC AGENT; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BONE CANCER; BREAST CANCER CELL LINE; CANCER PAIN; DOSE RESPONSE; FEMALE; GENE EXPRESSION; HYPERALGESIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SPINAL CORD DORSAL HORN; T LYMPHOCYTE; WALKER CARCINOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE TUMOR; CANCER TRANSPLANTATION; CARCINOMA; COMPLICATION; DISEASE MODEL; METABOLISM; PAIN; PAIN MEASUREMENT; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

RATTUS;

ANALGESICS; ANIMALS; BLOTTING, WESTERN; BONE NEOPLASMS; CARCINOMA 256, WALKER; CHEMOKINE CCL5; DISEASE MODELS, ANIMAL; DITERPENES; EPOXY COMPOUNDS; FEMALE; NEOPLASM TRANSPLANTATION; PAIN; PAIN MEASUREMENT; PHENANTHRENES; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; SPINAL CORD;

EID: 84925868835     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/bcpt.12265     Document Type: Article

References (27)

1. Middlemiss T, Laird BJ, Fallon MT. Mechanisms of cancer-induced bone pain. Clin Oncol (R Coll Radiol) 2011;23:387-92.
2. Somani S, Merchant S, Lalani S. A literature review about effectiveness of massage therapy for cancer pain. J Pak Med Assoc 2013;63:1418-21.
3. Wilson J, Stack C, Hester J. Recent advances in cancer pain management. F1000Prime Rep 2014;6:10.
4. Liu S, Liu YP, Song WB, Song XJ. EphrinB-EphB receptor signaling contributes to bone cancer pain via Toll-like receptor and proinflammatory cytokines in rat spinal cord. Pain 2013;154:2823-35.
5. Hu S, Mao-Ying QL, Wang J, Wang ZF, Mi WL, Wang XW et al. Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines. J Neuroinflammation 2012;9:278.
6. Guimarães AG, Serafini MR, Quintans-Júnior LJ. Terpenes and derivatives as a new perspective for pain treatment: a patent review. Expert Opin Ther Pat 2014;24:243-65.
7. Gertsch J, Leonti M, Raduner S, Racz I, Chen JZ, Xie XQ et al. Beta- caryophyllene is a dietary cannabinoid. Proc Natl Acad Sci U S A 2008;105:9099-104.
8. Hu JY, Li CL, Wang YW. Intrathecal administration of triptolide, a T lymphocyte inhibitor, attenuates chronic constriction injury-induced neuropathic pain in rats. Brain Res 2012;1436:122-9.
9. Wang W, Mei XP, Chen L, Tang J, Li JL, Wu SX et al. Triptolide prevents and attenuates neuropathic pain via inhibiting central immune response. Pain Physician 2012;15:E995-1006.
10. Tang J, Li ZH, Ge SN, Wang W, Mei XP, Zhang T et al. The inhibition of spinal astrocytic JAK2-STAT3 pathway activation correlates with the analgesic effects of triptolide in the rat neuropathic pain model. Evid Based Complement Alternat Med 2012;2012:185167.
11. Hang LH, Shao DH, Chen Z, Sun WJ. Spinal RhoA/Rho kinase signaling pathway may participate in the development of bone cancer pain. Basic Clin Pharmacol Toxicol 2013;113:87-91.
12. Hang LH, Yang JP, Shao DH, Chen Z, Wang H. Involvement of spinal PKA/CREB signaling pathway in the development of bone cancer pain. Pharmacol Rep 2013;65:710-6.
13. Hang LH, Yang JP, Yin W, Wang LN, Guo F, Ji FH et al. Activation of spinal TDAG8 and its downstream PKA signaling pathway contribute to bone cancer pain in rats. Eur J Neurosci 2012;36:2107-17.
14. Dixon WJ. Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol 1980;20:441-62.
15. Hang LH, Shao DH, Chen Z, Chen YF, Shu WW, Zhao ZG. Involvement of spinal CC chemokine ligand 5 in the development of bone cancer pain in rats. Basic Clin Pharmacol Toxicol 2013;113:325-8.
16. Doré-Savard L, Beaudet N, Tremblay L, Xiao Y, Lepage M, Sarret P. A micro-imaging study linking bone cancer pain with tumor growth and bone resorption in a rat model. Clin Exp Metastasis 2013;30:225-36.
17. Zhang R, Lao L. A new rat model of bone cancer pain. Methods Mol Biol 2012;851:261-73.
18. Muralidharan A, Smith MT. Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments. Inflammopharmacology 2013;21:339-63.
19. Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL 3rd. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain 2009;10:447-85.
20. Lozano-Ondoua AN, Symons-Liguori AM, Vanderah TW. Cancer-induced bone pain: mechanisms and models. Neurosci Lett 2013;557 (Pt A): 52-9.
21. Gui Q, Xu C, Zhuang L, Xia S, Chen Y, Peng P et al. A new rat model of bone cancer pain produced by rat breast cancer cells implantation of the shaft of femur at the third trochanter level. Cancer Biol Ther 2013;14:193-9.
22. Currie GL, Delaney A, Bennett MI, Dickenson AH, Egan KJ, Vesterinen HM et al. Animal models of bone cancer pain: systematic review and meta-analyses. Pain 2013;154:917-26.
23. Pevida M, González-Rodríguez S, Lastra A, García-Suárez O, Hidalgo A, Menéndez L et al. Involvement of spinal chemokine CCL2 in the hyperalgesia evoked by bone cancer in mice: a role for astroglia and microglia. Cell Mol Neurobiol 2014;34:143-56.
24. Mao-Ying QL, Wang XW, Yang CJ, Li X, Mi WL, Wu GC et al. Robust spinal neuroinflammation mediates mechanical hyperalgesia in Walker 256 induced bone cancer rats. Mol Brain 2012;5:16.
25. Wang XW, Li TT, Zhao J, Mao-Ying QL, Zhang H, Hu S et al. Extracellular signal-regulated kinase activation in spinal astrocytes and microglia contributes to cancer-induced bone pain in rats. Neuroscience 2012;217:172-81.
26. Sulaiman MR, Zakaria ZA, Abdul Rahman A, Mohamad AS, Desa MN, Stanslas J et al. Antinociceptive and antiedematogenic activities of andrographolide isolated from Andrographis paniculata in animal models. Biol Res Nurs 2010;11:293-301.
27. Pevida M, Lastra A, Meana Á, Hidalgo A, Baamonde A, Menéndez L. The chemokine CCL5 induces CCR1-mediated hyperalgesia in mice inoculated with NCTC 2472 tumoral cells. Neuroscience 2014;259:113-25.