A new rat model of bone cancer pain

Methods in Molecular Biology

Volumn 851, Issue , 2012, Pages 261-273

  Zhang, Ruixin ^a   Lao, Lixing ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Allodynia; Bone cancer pain; Hyperalgesia; Immuno histochemistry; Immunofluorescence; Metastatic bone tumors; Rat

Indexed keywords

ANIMAL; ARTICLE; BONE TUMOR; DISEASE MODEL; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MALE; PAIN; PATHOLOGY; PATHOPHYSIOLOGY; RAT; RAT STRAIN; TIBIA; TUMOR CELL LINE;

ANIMALS; BONE NEOPLASMS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MALE; PAIN; RATS; RATS, INBRED STRAINS; TIBIA;

RATTUS;

EID: 84858120644     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-561-9_20     Document Type: Article

References (12)

1. Foley, K. M. (2000) Controlling cancer pain. Hospital Practice 35 , 101-108.
2. Mercadante, S. (1997) Malignant bone pain: pathophysiology and treatment. Pain 69 , 1-18. (Pubitemid 27081402)
3. Reale, C., Turkiewicz, A. M., and Reale, C. A. (2001) Antalgic treatment of pain associated with bone metastases. Crit Rev Oncol Hematol 37 , 1-11. (Pubitemid 32063314)
4. Banning, A., Sjogren, P., and Henriksen, H. (1991) Treatment outcome in a multidisciplinary cancer pain clinic. Pain 47 , 129-134.
5. Bubendorf, L., Schopfer, A., Wagner, U., Sauter, G., Moch, H., Willi, N., Gasser, T. C., and Mihatsch, M. J. (2000) Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol 31 , 578-583. (Pubitemid 30323983)
6. Rana, A., Chisholm, G. D., Khan, M., Sekharjit, S. S., Merrick, M. V., and Elton, R. A. (1993) Patterns of bone metastasis and their prognostic signifi cance in patients with carcinoma of the prostate. Br J Urol 72 , 933-936. (Pubitemid 24053517)
7. Zhang, R.-X., Liu, B., Wang, L., Ren, K., Qiao, J.-T., Berman, B. M., and Lao, L. (2005) Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain 118 , 125-136. (Pubitemid 41566591)
8. Schwei, M. J., Honore, P., Rogers, S. D., Salak- Johnson, J. L., Finke, M. P., Ramnaraine, M. L., Clohisy, D. R., and Mantyh, P. W. (1999) Neurochemical and Cellular Reorganization of the Spinal Cord in a Murine Model of Bone Cancer Pain. J Neurosci 19 , 10886-10897. (Pubitemid 30235733)
9. Hargreaves, K., Dubner, R., Brown, F., Flores, C., and Joris, J. (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32 , 77-88.
10. Zhang, R. X., Lao, L., Qiao, J. T., and Ruda, M. A. (2004) Effects of aging on hyperalgesia and spinal dynorphin expression in rats with peripheral infl ammation. Brain Res 999 , 135-141. (Pubitemid 38121460)
11. Stein, C., Millan, M. J., and Herz, A. (1988) Unilateral infl ammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds. Pharmacol Biochem Behav 31 , 445-451. (Pubitemid 19275167)
12. Ren, K. (1999) An improved method for assessing mechanical allodynia in the rat. Physiol Behav 67 , 711-716.