A new rat model of bone cancer pain produced by rat breast cancer cells implantation of the shaft of femur at the third trochanter level

Cancer Biology and Therapy

Volumn 14, Issue 2, 2013, Pages 193-199

  Gui, Qi ^a   Xu, Chengcheng ^a   Zhuang, Liang ^a   Xia, Shu ^a   Chen, Yu ^a   Peng, Ping ^a   Yu, Shiying ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Bone metastases; Cancer pain; Rat model; The third trochanter; Walker 256 cell

Indexed keywords

PROTEIN C FOS; SUBSTANCE P; VANILLOID RECEPTOR 1;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MONITORING; BONE CANCER; BREAST CANCER; CANCER CELL; CANCER MODEL; CANCER PAIN; CANCER TRANSPLANTATION; CONTROLLED STUDY; CORTICAL BONE; DRILL; FEMALE; FEMUR SHAFT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; TUMOR GROWTH; WITHDRAWAL REFLEX;

BONE METASTASES; CANCER PAIN; RAT MODEL; THE THIRD TROCHANTER; WALKER 256 CELL;

ANIMALS; BEHAVIOR, ANIMAL; BONE NEOPLASMS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; FEMUR; HUMANS; MAGNETIC RESONANCE IMAGING; NEOPLASM TRANSPLANTATION; PAIN; RATS; SUBSTANCE P; TRPV CATION CHANNELS;

EID: 84873440268     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.23291     Document Type: Article

References (38)

1. Coleman RE. Skeletal complications of malignancy. Cancer 1997; 80(Suppl):1588-94; PMID:9362426; http://dx.doi.org/10.1002/(SICI)1097- 0142(19971015)80:8+;1588::AIDCNCR9; 3.0.CO;2-G.
2. Jimenez-Andrade JM, Mantyh WG, Bloom AP, Ferng AS, Geffre CP, Mantyh PW. Bone cancer pain. Ann N Y Acad Sci 2010; 1198:173-81; PMID:20536932; http://dx.doi.org/10.1111/j.1749-6632.2009.05429.x.
3. Zeppetella G. Impact and management of breakthrough pain in cancer. Curr Opin Support Palliat Care 2009; 3:1-6; PMID:19365156; http://dx.doi.org/10.1097/ SPC.0b013e3283260658.
4. Honore P, Mantyh PW. Bone cancer pain: from mechanism to model to therapy. Pain Med 2000; 1:303-9; PMID:15101876; http://dx.doi.org/10.1046/j. 1526-4637.2000.00047.x.
5. Sevcik MA, Luger NM, Mach DB, Sabino MA, Peters CM, Ghilardi JR, et al. Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis. Pain 2004; 111:169-80; PMID:15327821; http://dx.doi.org/10.1016/j.pain.2004.06.015.
6. Ghilardi JR, Freeman KT, Jimenez-Andrade JM, Mantyh WG, Bloom AP, Kuskowski MA, et al. Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain. Mol Pain 2010; 6:87; PMID:21138586; http://dx.doi.org/10.1186/1744-8069-6- 87.
7. Zhang RX, Liu B, Li A, Wang L, Ren K, Qiao JT, et al. Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation. Neuroscience 2008; 154:1533-8; PMID:18554806; http://dx.doi.org/10.1016/j.neuroscience.2008.04.072.
8. Colvin L, Fallon M. Challenges in cancer pain managementbone pain. Eur J Cancer 2008; 44:1083-90; PMID:18439817; http://dx.doi.org/10.1016/j.ejca.2008. 03.001.
9. Zhang RX, Liu B, Wang L, Ren K, Qiao JT, Berman BM, et al. Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain 2005; 118:125-36; PMID:16154703; http://dx.doi.org/10.1016/j.pain.2005.08.001.
10. De Ciantis PD, Yashpal K, Henry J, Singh G. Characterization of a rat model of metastatic prostate cancer bone pain. J Pain Res 2010; 3:213-21; PMID:21197325.
11. Doré-Savard L, Otis V, Belleville K, Lemire M, Archambault M, Tremblay L, et al. Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain. PLoS One 2010; 5:e13774; PMID:21048940; http://dx.doi.org/10.1371/journal. pone.0013774.
12. Dorfman HD, Czerniak B. Bone cancers. Cancer 1995; 75(Suppl):203-10; PMID:8000997; http://dx.doi.org/10.1002/1097-0142(19950101)75:1+;203:: AIDCNCR2820751308;3.0.CO;2-V.
13. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer statistics, 2008. CA Cancer J Clin 2008; 58:71-96; PMID:18287387; http://dx.doi.org/10.3322/CA.2007.0010.
14. Marina N, Gebhardt M, Teot L, Gorlick R. Biology and therapeutic advances for pediatric osteosarcoma. Oncologist 2004; 9:422-41; PMID:15266096; http://dx.doi.org/10.1634/theoncologist.9-4-422.
15. Roudier MP, Bain SD, Dougall WC. Effects of the RANKL inhibitor, osteoprotegerin, on the pain and histopathology of bone cancer in rats. Clin Exp Metastasis 2006; 23:167-75; PMID:16912914; http://dx.doi.org/10.1007/s10585- 006-9026-x.
16. Mao-Ying QL, Zhao J, Dong ZQ, Wang J, Yu J, Yan MF, et al. A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells. Biochem Biophys Res Commun 2006; 345:1292-8; PMID:16725112; http://dx.doi.org/10.1016/j.bbrc.2006.04.186.
17. Medhurst SJ, Walker K, Bowes M, Kidd BL, Glatt M, Muller M, et al. A rat model of bone cancer pain. Pain 2002; 96:129-40; PMID:11932069; http://dx.doi.org/10.1016/S0304-3959(01)00437-7.
18. Plunkett TA, Smith P, Rubens RD. Risk of complications from bone metastases in breast cancer. implications for management. Eur J Cancer 2000; 36:476-82; PMID:10717523; http://dx.doi.org/10.1016/S0959-8049(99)00331-7.
19. Lee YT. Breast carcinoma: pattern of metastasis at autopsy. J Surg Oncol 1983; 23:175-80; PMID:6345937; http://dx.doi.org/10.1002/jso.2930230311.
20. Proschek D, Mack MG, Kurth AA, Proschek P, Martin B, Hansmann ML, et al. Radiofrequency ablation of experimental bone metastases in nude rats. Anticancer Res 2008; 28(2A):879-85; PMID:18507032.
21. Yu S, Peng HD, Ju DW, Wei PK, Xu L, Lao LX, et al. Mechanisms of treatment of cancer pain with a topical Chinese herbal formula in rats. Chin Med J (Engl) 2009; 122:2027-31; PMID:19781391.
22. Cao F, Gao F, Xu AJ, Chen ZJ, Chen SS, Yang H, et al. Regulation of spinal neuroimmune responses by prolonged morphine treatment in a rat model of cancer induced bone pain. Brain Res 2010; 1326:162-73; PMID:20176002; http://dx.doi.org/10.1016/j.brainres.2010.02.039.
23. Peters CM, Ghilardi JR, Keyser CP, Kubota K, Lindsay TH, Luger NM, et al. Tumor-induced injury of primary afferent sensory nerve fibers in bone cancer pain. Exp Neurol 2005; 193:85-100; PMID:15817267; http://dx.doi.org/10.1016/j. expneurol.2004.11.028.
24. Ohlmann-Knafo S, Kirschbaum M, Fenzl G, Pickuth D. [Diagnostic value of whole-body MRI and bone scintigraphy in the detection of osseous metastases in patients with breast cancerA Prospective Double-Blinded Study at two Hospital Centers]. Rofo 2009; 181:255-63; PMID:19229791; http://dx.doi.org/10.1055/s- 0028-1109104.
25. Liu T, Cheng T, Xu W, Yan WL, Liu J, Yang HL. A meta-analysis of 18FDG-PET, MRI and bone scintigraphy for diagnosis of bone metastases in patients with breast cancer. Skeletal Radiol 2011; 40:523-31; PMID:20495798; http://dx.doi.org/10.1007/s00256-010-0963-8.
26. Hunt SP, Pini A, Evan G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 1987; 328:632-4; PMID:3112583; http://dx.doi.org/10.1038/328632a0.
27. Greenberg ME, Ziff EB, Greene LA. Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science 1986; 234:80-3; PMID:3749894; http://dx.doi.org/10.1126/science.3749894.
28. Ghilardi JR, Röhrich H, Lindsay TH, Sevcik MA, Schwei MJ, Kubota K, et al. Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain. J Neurosci 2005; 25:3126-31; PMID:15788769; http://dx.doi.org/10.1523/ JNEUROSCI.3815-04.2005.
29. Honore P, Chandran P, Hernandez G, Gauvin DM, Mikusa JP, Zhong C, et al. Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia. Pain 2009; 142:27-35; PMID:19135797; http://dx.doi.org/10.1016/j. pain.2008.11.004.
30. Niiyama Y, Kawamata T, Yamamoto J, Omote K, Namiki A. Bone cancer increases transient receptor potential vanilloid subfamily 1 expression within distinct subpopulations of dorsal root ganglion neurons. Neuroscience 2007; 148:560-72; PMID:17656027; http://dx.doi.org/10.1016/j.neuroscience.2007.05.049.
31. Park HC, Seong J, An JH, Kim J, Kim UJ, Lee BW. Alteration of cancer pain-related signals by radiation: proteomic analysis in an animal model with cancer bone invasion. Int J Radiat Oncol Biol Phys 2005; 61:1523-34; PMID:15817359; http://dx.doi.org/10.1016/j.ijrobp.2004.12.070.
32. Clohisy DR, Mantyh PW. Bone cancer pain. Cancer 2003; 97(Suppl):866-73; PMID:12548588; http://dx.doi.org/10.1002/cncr.11144.
33. Hald A, Nedergaard S, Hansen RR, Ding M, Heegaard AM. Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain. Eur J Pain 2009; 13:138-45; PMID:18499488; http://dx.doi.org/10.1016/j. ejpain.2008.03.014.
34. Nitzan-Luques A, Devor M, Tal M. Genotype-selective phenotypic switch in primary afferent neurons contributes to neuropathic pain. Pain 2011; 152:2413-26; PMID:21872992; http://dx.doi.org/10.1016/j.pain.2011.07.012.
35. Zhou Z, Peng X, Hagshenas J, Insolera R, Fink DJ, Mata M. A novel cell-cell signaling by microglial transmembrane TNFα with implications for neuropathic pain. Pain 2010; 151:296-306; PMID:20609516; http://dx.doi.org/10. 1016/j.pain.2010.06.017.
36. Parenti C, Aricò G, Ronsisvalle G, Scoto GM. Supraspinal injection of Substance P attenuates allodynia and hyperalgesia in a rat model of inflammatory pain. Peptides 2012; 34:412-8; PMID:22306475; http://dx.doi.org/10. 1016/j.peptides.2012.01.016.
37. Lu X, Geng X, Zhang L, Zeng Y, Dong H, Yu H. Substance P expression in the distal cerebrospinal fluid-contacting neurons and spinal trigeminal nucleus in formalin-induced the orofacial inflammatory pain in rats. Brain Res Bull 2009; 78:139-44; PMID:19103267; http://dx.doi.org/10.1016/j.brainresbull.2008. 11.011.
38. Erickson QL, Clark T, Larson K, Minsue Chen T. Flash freezing of Mohs micrographic surgery tissue can minimize freeze artifact and speed slide preparation. Dermatol Surg 2011; 37:503-9; PMID:21481069; http://dx.doi.org/10. 1111/j.1524-4725.2011.01926.x.