Analysis of the effect of different neuropeptides in gastric mucosal defense initiated centrally

Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract: Mechanisms, Prevention and Treatment

Volumn 30, Issue , 2012, Pages 161-169

  Gyires, Klara ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84925853656     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1159/000338428     Document Type: Chapter

References (30)

1. Holzer P: Neural emergency system in the stomach. Gastroenterology 1998;114:823-839.
2. Laine L, Takeuchi K, Tarnawski A: Gastric mucosal defense and cytoprotection: bench to bedside. Gastroenterology 2008;135:41-60.
3. Palkovits M: Interconnections between the neuroendocrine hypothalamus and the central autonomic system. Front Neuroendocrinol 1999;20:270-295.
4. Tache Y, Yoneda M: Central action of TRH to induce vagally mediated gastric cytoprotection and ulcer formation in rats. J Clin Gastroenterol 1993;17:S58-S63.
5. Tache Y: Brainstem neuropeptides and vagal protection of the gastric mucosal against injury: role of prostaglandins, nitric oxide and calcitonin-gene related peptide in capsaicin afferents. Curr Med Chem 2012;19:35-42.
6. Kaneko H, Mitsuma T, Nagai H, Mori S, Iyo T, Kusugami K, Tache Y: Central action of adrenomedullin to prevent ethanol-induced gastric injury through vagal pathways in rats. Am J Physiol 1998;274:R1783-R1788.
7. Yang H, Kawakubo K, Tache Y: Intracisternal PYY increases gastric mucosal resistance: role of cholinergic, CGRP, and NO pathways. Am J Physiol Gastrointest Liver Physiol 1999;277:G555-G562.
8. Guidobono F, Pagani F, Ticozzi C, Sibilia V, Pecile A, Netti C: Protection by amylin of gastric erosions induced by indomethacin or ethanol in rats. Br J Pharmacol 1997;120:581-586.
9. Brzozowski T, Konturek PC, Pajdo R, Kwiecien S, Ptak A, Sliwowski Z, Drozdowicz D, Pawlik M, Konturek SJ, Hahn EG: Brain-gut axis in gastroprotection by leptin and cholecystokinin against ischemia-reperfusion induced gastric lesions. J Physiol Pharmacol 2001;52:583-602.
10. Brzozowski T, Konturek PC, Sliwowski Z, Drozdowicz D, Kwiecien S, Pawlik M, Pajdo R, Konturek SJ, Pawlik WW, Hahn EG: Neural aspects of ghrelin-induced gastroprotection against mucosal injury induced by noxious agents. J Physiol Pharmacol 2006;57(suppl 6):63-76.
11. Gyires K, Ronai AZ: Supraspinal delta-and mu-opioid receptors mediate gastric mucosal protection in the rat. J Pharmacol Exp Ther 2001;297:1010-1015.
12. Gyires K, Zadori ZS, Ronai AZ, Tekes K, Nemeth J:Role of central nervous system in regulation of gastrointestinal functions: experimental evidence on the significant role of endomorphin-2 in gastric mucosal defence. Acta Physiol 2011;202(suppl 684):37-38.
13. Zadori ZS, Shujaa N, Koles L, Kiraly KP, Tekes K, Gyires K: Nocistatin and nociceptin given centrally induce opioid-mediated gastric mucosal protection. Peptides 2008;29:2257-2265.
14. Sibilia V, Pagani F, Bulgarelli I, Mrak E, Broccardo M, Improta G, Severini C, Possenti R, Guidobono F:TLQP-21, a VGF-derived peptide, prevents ethanolinduced gastric lesions: insights into its mode of action. Neuroendocrinology 2010;92:189-197.
15. Zadori ZS, Brancati SB, Shujaa N, Gyires K: Analysis of the gastroprotective effect of substance P in rats. Acta Physiol 2011;202(suppl 684):131.
16. Broccardo M, Guerrini R, Petrella C, Improta G: Gastrointestinal effects of intracerebroventricularly injected nociceptin/orphanin FQ in rats. Peptides 2004;25:1013-1020.
17. Guidobono F, Coluzzi M, Pagani F, Pecile A, Netti C: Amylin given by central and peripheral routes inhibits acid gastric-secretion. Peptides 1994;15:699-702.
18. Mullner K, Ronai AZ. Fulop K, Furst S, Gyires K: Involvement of central K-ATP channels in the gastric antisecretory action of alpha(2)-adrenoceptor agonists and beta-endorphin in rats. Eur J Pharmacol 2002;435:225-229.
19. Sibilia V, Pagani F, Bulgarelli I, Tulipano G, Possenti R, Guidobono F: Characterization of the mechanisms involved in the gastric antisecretory effect of TLQP-21, a VGF-derived peptide, in rats. Amino Acids 2010 [Epub ahead of print].
20. Gyires K: Neuropeptides and gastric mucosal homeostasis. Curr Top Med Chem 2004;4:63-73.
21. Sibilia V, Pagani F, Rindi G, Lattuada N, Rapetti D, De Luca V, Campanini N, Bulgarelli I, Locatelli V, Guidobono F, Netti C: Central ghrelin gastroprotection involves nitric oxide/prostaglandin cross-talk. Br J Pharmacol 2008;154:688-697.
22. Guidobono F, Pagani F, Ticozzi C, Sibilia V, Netti C: Investigation on the mechanisms involved in the central protective effect of amylin on gastric ulcers in rats. Br J Pharmacol 1998;125:23-28.
23. Guo JJ, Browning KN, Rogers RC, Travagli RA: Catecholaminergic neurons in rat dorsal motor nucleus of vagus project selectively to gastric corpus. Am J Physiol Gastrointest Liver Physiol 2001;280:G361-G367.
24. Takeuchi K, Kato S, Hirata T, Nishiwaki H: Gastric motility and mucosal ulcerogenic responses induced by prokinetic drugs in rats under prostaglandindeficient conditions. Dig Dis Sci 1997;42:251-258.
25. Sevigny CP, Bassi J, Williams DA, Anderson CR, Thomas WG, Allen AM: Efferent projections of C3 adrenergic neurons in the rat central nervous system. J Comp Neurol DOI: 10.1002/cne.23041
26. Ko JK, Cho CH: The mechanistic pathway of gastric adaptive cytoprotection: a study on different components of the autonomic nervous system. J Auton Pharmacol 1995;15:205-214.
27. Brzozowski T, Konturek SJ, Sliwowski Z, Pajdo R, Drozdowicz D, Stachura J: Role of betaadrenoceptors in gastric mucosal integrity and gastroprotection induced by epidermal growth factor. Digestion 1997;58:319-331.
28. Zhang YM, Wei EQ, Hu X, Xu M, Shi Y, Zhang JF: Administration of angiotensin II in the paraventricular nucleus protects gastric mucosa from ischemia-reperfusion injury. Brain Res 2008;1212:25-34.
29. Polidori C, Massi M, Guerrini R, Grandi D, Lupo D, Morini G: Peripheral mechanisms involved in gastric mucosal protection by intracerebroventricular and intraperitoneal nociceptin in rats. Endocrinology 2005;146:3861-3867.
30. Filaretova L: The hypothalamic-pituitary-adrenocortical system: hormonal brain-gut interaction and gastroprotection. Auton Neurosci 2006;125: 86-93.