Peripheral mechanisms involved in gastric mucosal protection by intracerebroventricular and intraperitoneal nociceptin in rats

Endocrinology

Volumn 146, Issue 9, 2005, Pages 3861-3867

  Polidori, Carlo ^a   Massi, Maurizio ^a   Guerrini, Remo ^b   Grandi, Daniela ^c   Lupo, Daniela ^c   Morini, Giuseppina ^a,c  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Afferent nerve fibers; Ethanol induced gastric damage; Nitric oxide; Nociceptin; Parasympathetic and sympathetic systems

Indexed keywords

ALCOHOL; ATROPINE; BRETYLIUM; CALCITONIN GENE RELATED PEPTIDE[8-37]; CAPSAICIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NOCICEPTIN;

ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; MALE; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT; SENSORY NERVE; STOMACH MUCOSA; STOMACH MUCOSA LESION; STOMACH PROTECTION; TISSUE INJURY; VAGOTOMY;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATROPINE; BRETYLIUM COMPOUNDS; CALCITONIN GENE-RELATED PEPTIDE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; GANGLIONIC BLOCKERS; GASTRIC MUCOSA; HEXAMETHONIUM; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENTRICULAR; MALE; MIOTICS; NEURONS, AFFERENT; NITRIC OXIDE; OPIOID PEPTIDES; PARASYMPATHETIC NERVOUS SYSTEM; PARASYMPATHOLYTICS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SYMPATHETIC NERVOUS SYSTEM; VAGOTOMY;

EID: 23844542813     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-0397     Document Type: Article

References (46)

1. Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, Alvinerie P, Butour JL, Guillemot JC, Ferrara P, Monsarrat B, Mazarguil H, Vassart G, Parmentier M, Costentin J 1995 Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377:532-535
2. Reinscheid RK, Nothacker H, Bourson A, Ardati A, Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma FJ, Civelli O 1995 Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270:792-794
3. Mogil JS, Pasternak GW 2001 The molecular and behavioral pharmacology of the orphaninFQ/nociceptin peptide and receptor family. Pharmacol Rev 53:381-415
4. Pomonis JD, Billington CJ, Levine AS 1996 Orphanin FQ, agonist of orphan opioid receptor ORL1, stimulates feeling in rats. Neuroreport 8:369-371
5. Olszewski PK, Levine AS 2004 Minireview: Characterization of influence of central nociceptin/orphanin FQ on consummatory behavior. Endocrinology 145:2627-2632
6. Polidori C, De Caro G, Massi M 2000 The hyperphagic effect of nociceptin/orphanin FQ in rats. Peptides 21:1051-1062
7. Yazdani A, Takahashi T, Bagnol D, Watson SJ, Owyang C 1999 Functional significance of a newly discovered neuropeptide, orphanin FQ, in rat gastrointestinal motility. Gastroenterology 116:108-117
8. 2 stimulate gastric motor function in anaesthetized rats. Br J Pharmacol 130:1639-1645
9. Takahashi T, Mizuta Y, Owyang C 2000 Orphanin FQ, but not dynorphin A, accelerates colonic transit in rats. Gastroenterology 119:71-79
10. Ishihara S, Minowa S, Tsuchiya S, Horie S, Watanabe K, Murayama T 2002 Gastric acid secretion stimulated by centrally injected nociceptin in urethane-anesthetized rats. Eur J Pharmacol 441:105-114
11. Broccardo M, Guerrini R, Putrella C, Improta G 2004 Gastrointestinal effects of intracerebroventricularly injected nociceptin/orphaninFQ in rats. Peptides 25:1013-1020
12. Morini G, De Caro G, Guerrini R, Massi M, Polidori C 2004 Nociceptin/orphanin FQ prevents ethanol-induced gastric lesion in the rat. Regul Pept 124:203-207
13. Mollereau C, Mouledous L 2000 Tissue distribution of the opioid receptor-like (ORL1) receptor. Peptides 21:907-917
14. Wang JB, Johnson PS, Imai Y, Persico AM, Ozenberger BA, Epller CM, Uhl GR 1994 cDNA cloning of an orphan opiate receptor gene family member and its splice variant. FEBS Lett 348:75-79
15. Holzer P 1998 Neural emergency system in the stomach. Gastroenterology 114:823-839
16. Whittle BJR 1993 Neuronal and endothelium-derived mediators in the modulation of the gastric microcirculation: integrity in the balance. Br J Pharmacol 110:3-17
17. Király Á, Süt G, Taché Y 1993 Role of nitric oxide in the gastric cytoprotection induced by central vagal stimulation. Eur J Pharmacol 240:299-301
18. Taché Y, Yoneda M, Kato K, Király Á, Sütö G, Kaneko H 1994 Intracisternal thyrotropin-releasing hormone-induced vagally mediated gastric protection against ethanol lesions: central and pheripheral mechanisms. J Gastroenterol Hepatol 9:S29-S35
19. Yang H, Kawakubo K, Taché Y 1999 Intracisternal PYY increases gastric mucosal resistance: role of cholinergic, CGRP, and NO pathways. Am J Physiol 277:G555-G562
20. Kaneko H, Mitsuma T, Nagai H, Mori S, Iyo T, Tachè Y 1998 Central action of adrenomedullin to prevent ethanol-induced gastric injury through vagal pathways in rats. Am J Physil 274:R1783-R1788
21. Gyres K, Rónai AZ, Müllner K, Fürst S 2000 Intracerebroventricular injection of clonidine releases β-endorphin to induce mucosal protection in the rat. Neuropharmacol 39:961-968
22. Kacker V, Mehta VS, Gupta YK 1999 Acute intracranial hypertension-induced inhibition of gastric emptyng: evaluation in conscious rats. Eur J Pharmacol 369:65-72
23. Guidobono F, Pagani F, Sibilia V, Soglian A, Rapetti D, Netti C 2000 The role of sensory neurons in the antiulcer effect of centrally injected amylin in rat. Peptides 21:1537-1541
24. Morini G, Guaita E, Coruzzi G, Grandi D, Schunack W 2001 Gastroprotection by (R)-α-methylhistamine: involvement of nitric oxide? Inflamm. Res 50:S114-S115
25. Lacy ER, Ito S 1982 Microscopic analysis of ethanol damage to rat gastric mucosa after treatment with a prostaglandin. Gastroenterology 83:619-625
26. Szabo S, Trier JS, Brown A, Schnoor J 1985 Early vascular injury and increased vascular permeability in gastric mucosal injury caused by ethanol in the rat. Gastroenterology 88:228-236
27. Foschi D, Castoldi L, Del Soldato P, Musazzi M, Callioni F, Rovati V, Trabucchi E, Montorsi W 1989 Effects of autonomic nervous system on gastric damage by ethanol in the rat. Dig Dis Sci 34:688-693
28. Henagan JM, Smith GS, Seidel ER, Miller TA 1984 Influence of vagotomy on mucosal protection against alcohol-induced gastric damage in the rat. Gastroenterology 87:903-908
29. Mozsik G, Moron F, Javor T 1982 Cellular mechanism of the development of gastric mucosal damage and gastrocytoprotection induced by prostacyclin in rats. A pharmacological study. Prostaglandins Leukot Med 9:71-84
30. Agostoni E, Chinnock JE, De Daly MB, Murray JG 1957 Functional and histological studies of the vagus nerve and its branches to the heart, lungs and abdominal viscera in the cat. J Physiol 135:182-205
31. Berthoud H, Patterson LM, Willing AE, Mueller K, Neuhuber WL 1997 Capsaicin-resistant vagal afferent fibers in the rat gastrointestinal tract: anatomical identification and functional integrity. Brain Research 746:195-206
32. Holzer P 2000 Local microcirculatory reflexes and afferent signalling in response to gastric acid challenge. Gut 47:iv46-iv48
33. Chen RY, Li DS, Guth PH 1992 Role of calcitonin gene-related peptide in capsaicininduced gastric submucosal arteriolar dilation. Am J Physiol 262:H1350-H1355
34. Abdelrahman AM, Pang CC 2002 Regional hemodynamic effects of nociceptin/orphanin FQ in the anesthetized rat. Eur J Pharmacol 450:263-266
35. Champion HC, Kadowitz PJ 1997 Nociceptin, an endogenous ligand for the ORL1 receptor, has novel hypotensive activity in the rat. Life Sci 60:PL241-PL245
36. Giuliani S, Tramontana M, Lecci A, Maggi C A 1997 Effect of nociceptin on heart rate and blood pressure in anaesthetized rats. Eur J Pharmacol 333:177-179
37. Drüge G, Raedler A, Greten H, Lenz HJ 1989 Pathways mediating CRF-induced inhibition of gastric acid secretion in rats. Am J Physiol 256:G214-G219
38. Katafuchi T, Ichijo T, Hori T 1997 Sequential relationship between actions of CRF and PGE2 in the brain on splenic sympathetic nerve activity in rats. J Auton Nerv Syst 67:200-206
39. Wang L, Cardin S, Martínez V, Taché Y 1996 Intracerebroventricular CRF inhibits cold restraint-induced c-fos expression in the dorsal motor nucleus of the vagus and gastric erosions in rats. Brain Research 736:44-53
40. Taché Y, Martìnez V, Million M, Wang L 2001 Stress and gastrointestinal tract III. Stress-related alterations of gut motor function: role of brain corticotropin-releasing factor receptors. Am J Physiol 280:G173-G177
41. Beck B 2000 Neuropeptides and obesity. Nutrition 16:916-923
42. Dhillo WS, Bloom SR 2004 Gastrointestinal hormones and regulation of food intake. Horm Metab Res 36:846-851
43. Zorrilla EP, Tachè Y, Koob GF 2003 Nibbling at CRF receptor control of feeding and gastrocolonic motility. Trends Pharmacol Sci 24: 421-427
44. Fujimiya M, Inui A 2000 Peptidergic regulation of gastrointestinal motility in rodents. Peptides 21:1565-1582
45. Murray CDR, Kamm MA, Bloom SR, Emmanuel AV 2003 Ghrelin for the gastroenterologist: history and potential. Gastroenterology 125:1492-1502
46. Ciccocioppo R, Cippittelli A, Economidou D, Fedeli A, Massi M 2004 Nociceptin /orphanin FQ acts as a functional antagonist of corticotropin- releasing factor to inhibit its anorectic effect. Physiol Behav 82:63-68