Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Lee, Chen Ting ^a   Kokolus, Kathleen M ^a   Leigh, Nicholas D ^a   Capitano, Maegan ^a   Hylander, Bonnie L ^a   Repasky, Elizabeth A ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CD11B ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; COLLAGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; JANUS KINASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; METHOTREXATE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BCL 2; RANTES; STAT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; ANTIBODY; ANTIRHEUMATIC AGENT; CYTOKINE; HEAT SHOCK PROTEIN; STAT1 PROTEIN;

ALTERNATIVE MEDICINE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CELL ISOLATION; CHROMATIN IMMUNOPRECIPITATION; CLINICAL EFFECTIVENESS; COLLAGEN-INDUCED ARTHRITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; DOWN REGULATION; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HEAT STRESS; HISTOPATHOLOGY; HYPERTHERMIC THERAPY; IMMUNE DEFICIENCY; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INGUINAL LYMPH NODE; JOINT INJURY; MACROPHAGE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN PHOSPHORYLATION; QUALITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; RNA EXTRACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; JOINT; MACROPHAGE ACTIVATION; METABOLISM; MULTIMODALITY CANCER THERAPY; PATHOLOGY; THERMOTHERAPY;

MURINAE; MUS;

ANIMALS; ANTIBODIES; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; COMBINED MODALITY THERAPY; CYTOKINES; DISEASE MODELS, ANIMAL; HEAT-SHOCK PROTEINS; HYPERTHERMIA, INDUCED; JOINTS; MACROPHAGE ACTIVATION; MACROPHAGES; METHOTREXATE; MICE; NF-KAPPA B; STAT1 TRANSCRIPTION FACTOR; T-LYMPHOCYTES;

EID: 84925799562     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120327     Document Type: Article

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