Near infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Maawy, Ali A ^a   Hiroshima, Yukihiko ^a,b,c   Zhang, Yong ^b   Heim, Roger ^d   Makings, Lew ^d   Garcia Guzman, Miguel ^d   Luiken, George A ^e   Kobayashi, Hisataka ^f   Hoffman, Robert M ^a,b   Bouvet, Michael ^a,g  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b ANTICANCER INC   (United States)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d Aspyrian Therapeutics Inc   (United States)

^e OncoFluor Inc   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; GREEN FLUORESCENT PROTEIN; PHTHALOCYANINE DERIVATIVE; MONOCLONAL ANTIBODY; RADIOSENSITIZING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW LEVEL LASER THERAPY; MOUSE; MOUSE MODEL; NONHUMAN; PANCREAS CANCER; PANCREATIC CANCER CELL LINE; PHOTOIMMUNOTHERAPY; PHOTOTHERAPY; TUMOR CELL DESTRUCTION; TUMOR ENGRAFTMENT; TUMOR REGRESSION; ANIMAL; DRUG SCREENING; IMMUNOLOGY; IMMUNOTHERAPY; INFRARED RADIATION; NUDE MOUSE; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALIA; MUS; MUS MUSCULUS;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOEMBRYONIC ANTIGEN; CELL LINE, TUMOR; HUMANS; IMMUNOTHERAPY; INFRARED RAYS; MICE; MICE, NUDE; PANCREATIC NEOPLASMS; PHOTOTHERAPY; RADIATION-SENSITIZING AGENTS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84925740489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121989     Document Type: Article

References (23)

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