Fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA), that highlights the tumor, improves surgical resection and increases survival in orthotopic mouse models of human pancreatic cancer

Annals of Surgical Oncology

Volumn 21, Issue 4, 2014, Pages 1405-1411

  Metildi, Cristina A ^a   Kaushal, Sharmeela ^b   Pu, Minya ^b   Messer, Karen A ^b   Luiken, George A ^c   Moossa, Abdool R ^a   Hoffman, Robert M ^a,b,d   Bouvet, Michael ^a,b,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c OncoFluor Inc   (United States)

^d ANTICANCER INC   (United States)

^e VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; CARCINOEMBRYONIC ANTIGEN; CARCINOEMBRYONIC ANTIGEN ALEXA FLUOR 488 ANTIBODY CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRIGHT LIGHT SURGERY; CANCER MODEL; CANCER SURGERY; CANCER SURVIVAL; DISEASE FREE SURVIVAL; FEMALE; FLUORESCENCE GUIDED SURGERY; MOUSE; NONHUMAN; NUDE MOUSE; OVERALL SURVIVAL; PANCREAS CANCER; POSTOPERATIVE PERIOD; SURGICAL TECHNIQUE; SURVIVAL RATE;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOEMBRYONIC ANTIGEN; DIAGNOSTIC IMAGING; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; HUMANS; MICE; MICE, NUDE; PANCREATIC NEOPLASMS; SURVIVAL RATE; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896085965     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-014-3495-y     Document Type: Article

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