Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin

Oncotarget

Volumn 6, Issue 8, 2015, Pages 6295-6309

  Savaraj, Niramol ^a,b   Wu, Chunjing ^a   Li, Ying Ying ^b   Wangpaichitr, Medhi ^a,b   You, Min ^b   Bomalaski, John ^c   He, Wei ^c   Kuo, Macus Tien ^d   Feun, Lynn G ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Polaris Group   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Arginine deiminase; Argininosuccinate synthetase; Cisplatin; Melanoma

Indexed keywords

ARGININOSUCCINATE SYNTHASE; ATM PROTEIN; B RAF KINASE; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CISPLATIN; FANCONI ANEMIA GROUP D2 PROTEIN; PEGARGIMINASE; PROTEIN BCL 2; PROTEIN NOXA; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS; ANTINEOPLASTIC AGENT; ARGININE; HYDROLASE; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MELANOMA CELL LINE; MONOTHERAPY; MOUSE; NONHUMAN; TUMOR REGRESSION; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CITRULLINEMIA; DRUG EFFECTS; DRUG SCREENING; ENZYMOLOGY; HUMAN; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; ARGININE; ARGININOSUCCINATE SYNTHASE; CELL LINE, TUMOR; CISPLATIN; CITRULLINEMIA; FEMALE; HUMANS; HYDROLASES; MELANOMA; MICE; MICE, INBRED BALB C; MICE, NUDE; POLYETHYLENE GLYCOLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84925689127     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3370     Document Type: Article

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