-
1
-
-
34249723214
-
Opportunities for improving the therapeutic ratio for patients with sarcoma
-
DOI 10.1016/S1470-2045(07)70169-9, PII S1470204507701699
-
Wunder JS, Nielsen TO, Maki RG, O'Sullivan B, Alman BA (2007) Opportunities for improving the therapeutic ratio for patients with sarcoma. Lancet Oncol 8: 513-524. (Pubitemid 46823060)
-
(2007)
Lancet Oncology
, vol.8
, Issue.6
, pp. 513-524
-
-
Wunder, J.S.1
Nielsen, T.O.2
Maki, R.G.3
O'Sullivan, B.4
Alman, B.A.5
-
2
-
-
43549101708
-
The clinical approach towards chondrosarcoma
-
DOI 10.1634/theoncologist.2007-0237
-
Gelderblom H, Hogendoorn PC, Dijkstra SD, van Rijswijk CS, Krol AD, et al (2008) The clinical approach towards chondrosarcoma. Oncologist 13: 320-329. (Pubitemid 351679908)
-
(2008)
Oncologist
, vol.13
, Issue.3
, pp. 320-329
-
-
Gelderblom, H.1
Hogendoorn, P.C.W.2
Dijkstra, S.D.3
Van Rijswijk, C.S.4
Krol, A.D.5
Taminiau, A.H.M.6
Bovee, J.V.M.G.7
-
4
-
-
22944487703
-
Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment
-
DOI 10.1016/S1470-2045(05)70282-5, PII S1470204505702825
-
Bovee JV, Cleton-Jansen AM, Taminiau AH, Hogendoorn PC (2005) Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment. Lancet Oncol 6: 599-607. (Pubitemid 41051938)
-
(2005)
Lancet Oncology
, vol.6
, Issue.8
, pp. 599-607
-
-
Bovee, J.V.M.G.1
Cleton-Jansen, A.-M.2
Taminiau, A.H.M.3
Hogendoorn, P.C.W.4
-
5
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17: 9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
6
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
7
-
-
0041695485
-
A second canon: Functions and mechanisms of beta-catenin-independent Wnt signaling
-
DOI 10.1016/S1534-5807(03)00266-1, PII S1534580703002661
-
Veeman MT, Axelrod JD, Moon RT (2003) A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 5: 367-377. (Pubitemid 37107667)
-
(2003)
Developmental Cell
, vol.5
, Issue.3
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
8
-
-
42549096546
-
Beyond Wnt inhibition: New functions of secreted Frizzled-related proteins in development and disease
-
DOI 10.1242/jcs.026096
-
Bovolenta P, Esteve P, Ruiz JM, Cisneros E, Lopez-Rios J (2008) Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J Cell Sci 121: 737-746. (Pubitemid 351578109)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.6
, pp. 737-746
-
-
Bovolenta, P.1
Esteve, P.2
Ruiz, J.M.3
Cisneros, E.4
Lopez-Rios, J.5
-
9
-
-
0032556910
-
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
-
DOI 10.1038/34848
-
Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, et al (1998) Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391: 357-362. (Pubitemid 28093502)
-
(1998)
Nature
, vol.391
, Issue.6665
, pp. 357-362
-
-
Glinka, A.1
Wu, W.2
Delius, H.3
Monaghan, A.P.4
Blumenstock, C.5
Niehrs, C.6
-
10
-
-
33845359084
-
Function and biological roles of the Dickkopf family of Wnt modulators
-
Niehrs C Function and biological roles of the Dickkopf family of Wnt modulators (2006) Oncogene 25: 7469-7481.
-
(2006)
Oncogene
, vol.25
, pp. 7469-7481
-
-
Niehrs, C.1
-
11
-
-
47949085566
-
Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density
-
Ellwanger K, Saito H, Clement-Lacroix P, Maltry N, Niedermeyer J, et al (2008) Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol 28: 4875-4882.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4875-4882
-
-
Ellwanger, K.1
Saito, H.2
Clement-Lacroix, P.3
Maltry, N.4
Niedermeyer, J.5
-
12
-
-
9144240010
-
DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway
-
DOI 10.1038/sj.onc.1207892
-
Niida A, Hiroko T, Kasai M, Furukawa Y, Nakamura Y, et al (2004) DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene 23: 8520-8526. (Pubitemid 39540802)
-
(2004)
Oncogene
, vol.23
, Issue.52
, pp. 8520-8526
-
-
Niida, A.1
Hiroko, T.2
Kasai, M.3
Furukawa, Y.4
Nakamura, Y.5
Suzuki, Y.6
Sugano, S.7
Akiyama, T.8
-
14
-
-
33745765883
-
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
-
DOI 10.1038/sj.onc.1209439, PII 1209439
-
Aguilera O, Fraga MF, Ballestar E, Paz MF, Herranz M, et al (2006) Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene 25: 4116-4121. (Pubitemid 44024874)
-
(2006)
Oncogene
, vol.25
, Issue.29
, pp. 4116-4121
-
-
Aguilera, O.1
Fraga, M.F.2
Ballestar, E.3
Paz, M.F.4
Herranz, M.5
Espada, J.6
Garcia, J.M.7
Muoz, A.8
Esteller, M.9
Gonzalez-Sancho, J.M.10
-
15
-
-
34547674539
-
Preferential hypermethylation of the Dickkopf-1 promoter in core-binding factor leukaemia
-
DOI 10.1111/j.1365-2141.2007.06702.x
-
Suzuki R, Onizuka M, Kojima M, Shimada M, Fukagawa S, et al (2007) Preferential hypermethylation of the Dickkopf-1 promoter in core-binding factor leukaemia. Br J Haematol 138: 624-631. (Pubitemid 47208475)
-
(2007)
British Journal of Haematology
, vol.138
, Issue.5
, pp. 624-631
-
-
Suzuki, R.1
Onizuka, M.2
Kojima, M.3
Shimada, M.4
Fukagawa, S.5
Tsuboi, K.6
Kobayashi, H.7
Shintani, A.8
Ogawa, Y.9
Kawada, H.10
Hotta, T.11
Ando, K.12
-
16
-
-
33747348443
-
Expression of Dickkopf genes is strongly reduced in malignant melanoma
-
Kuphal S, Lodermeyer S, Bataille F, Schuierer M, Hoang BH, et al (2006) Expression of Dickkopf genes is strongly reduced in malignant melanoma. Oncogene 25: 5027-5036.
-
(2006)
Oncogene
, vol.25
, pp. 5027-5036
-
-
Kuphal, S.1
Lodermeyer, S.2
Bataille, F.3
Schuierer, M.4
Hoang, B.H.5
-
17
-
-
13944282066
-
The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer
-
DOI 10.1038/sj.onc.1208303
-
Gonzalez-Sancho JM, Aguilera O, Garcia JM, Pendas-Franco N, Pena C, et al (2005) The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. Oncogene. 24: 1098-1103. (Pubitemid 40313887)
-
(2005)
Oncogene
, vol.24
, Issue.6
, pp. 1098-1103
-
-
Gonzalez-Sancho, J.M.1
Aguilera, O.2
Garcia, J.M.3
Pendas-Franco, N.4
Pena, C.5
Cal, S.6
De Herreros, A.G.7
Bonilla, F.8
Munoz, A.9
-
18
-
-
33847224852
-
The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types
-
Forget MA, Turcotte S, Beauseigle D, Godin-Ethier J, Pelletier S, et al (2007) The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types. Br J Cancer 96: 646-653.
-
(2007)
Br J Cancer
, vol.96
, pp. 646-653
-
-
Forget, M.A.1
Turcotte, S.2
Beauseigle, D.3
Godin-Ethier, J.4
Pelletier, S.5
-
19
-
-
34047270776
-
Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas
-
DOI 10.1158/0008-5472.CAN-06-3369
-
Yamabuki T, Takano A, Hayama S, Ishikawa N, Kato T, et al (2007) Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas. Cancer Res 67: 2517-2525. (Pubitemid 46548936)
-
(2007)
Cancer Research
, vol.67
, Issue.6
, pp. 2517-2525
-
-
Yamabuki, T.1
Takano, A.2
Hayama, S.3
Ishikawa, N.4
Kato, T.5
Miyamoto, M.6
Ito, T.7
Ito, H.8
Miyagi, Y.9
Nakayama, H.10
Fujita, M.11
Hosokawa, M.12
Tsuchiya, E.13
Kohno, N.14
Kondo, S.15
Nakamura, Y.16
Daigo, Y.17
-
20
-
-
0346363760
-
The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma
-
DOI 10.1056/NEJMoa030847
-
Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, et al (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349: 2483-2494. (Pubitemid 38010074)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.26
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
Barlogie, B.6
Shaughnessy Jr., J.D.7
-
21
-
-
64749106861
-
Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas
-
Yu B, Yang X, Xu Y, Yao G, Shu H, et al (2009) Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas. J Hepatol 50: 948-957.
-
(2009)
J Hepatol
, vol.50
, pp. 948-957
-
-
Yu, B.1
Yang, X.2
Xu, Y.3
Yao, G.4
Shu, H.5
-
22
-
-
36448991576
-
A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies
-
DOI 10.1038/sj.bjc.6604069, PII 6604069
-
Lee N, Smolarz AJ, Olson S, David O, Reiser J, et al (2007) A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. Br J Cancer 97: 1552-1559. (Pubitemid 350175854)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.11
, pp. 1552-1559
-
-
Lee, N.1
Smolarz, A.J.2
Olson, S.3
David, O.4
Reiser, J.5
Kutner, R.6
Daw, N.C.7
Prockop, D.J.8
Horwitz, E.M.9
Gregory, C.A.10
-
23
-
-
34948859456
-
Increased Dickkopf-1 expression in breast cancer bone metastases
-
DOI 10.1038/sj.bjc.6603959, PII 6603959
-
Voorzanger-Rousselot N, Goehrig D, Journe F, Doriath V, Body JJ, et al (2007) Increased Dickkopf-1 expression in breast cancer bone metastases. Br J Cancer 97: 964-970. (Pubitemid 47519305)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.7
, pp. 964-970
-
-
Voorzanger-Rousselot, N.1
Goehrig, D.2
Journe, F.3
Doriath, V.4
Body, J.J.5
Clezardin, P.6
Garnero, P.7
-
24
-
-
33645006198
-
Role of Wnts in prostate cancer bone metastases
-
Hall CL, Kang S, MacDougald OA, et al (2006) Role of Wnts in prostate cancer bone metastases. J Cell Biochem 97: 661-672.
-
(2006)
J Cell Biochem
, vol.97
, pp. 661-672
-
-
Hall, C.L.1
Kang, S.2
MacDougald, O.A.3
-
25
-
-
0033547371
-
Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas
-
Terris B, Pineau P, Bregeaud L, Keller ET (1999) Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas. Oncogene 18: 6583-6588.
-
(1999)
Oncogene
, vol.18
, pp. 6583-6588
-
-
Terris, B.1
Pineau, P.2
Bregeaud, L.3
Keller, E.T.4
-
26
-
-
0036888309
-
Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma
-
DOI 10.1002/ijc.10719
-
Haydon RC, Deyrup A, Ishikawa A, Heck R, Jiang W, et al (2002). Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma. Int J Cancer 102: 338-342. (Pubitemid 35265873)
-
(2002)
International Journal of Cancer
, vol.102
, Issue.4
, pp. 338-342
-
-
Haydon, R.C.1
Deyrup, A.2
Ishikawa, A.3
Heck, R.4
Jiang, W.5
Zhou, L.6
Feng, T.7
King, D.8
Cheng, H.9
Breyer, B.10
Peabody, T.11
Simon, M.A.12
Montag, A.G.13
He, T.-C.14
-
27
-
-
0033658259
-
Prognostic value of the preserved expression of the E-cadherin and catenin families of adhesion molecules and of beta-catenin mutations in synovial sarcoma
-
Saito T, Oda Y, Sakamoto A, Tamiya S, Kinukawa N, et al (2000) Prognostic value of the preserved expression of the E-cadherin and catenin families of adhesion molecules and of beta-catenin mutations in synovial sarcoma. J Pathol 192: 342-350.
-
(2000)
J Pathol
, vol.192
, pp. 342-350
-
-
Saito, T.1
Oda, Y.2
Sakamoto, A.3
Tamiya, S.4
Kinukawa, N.5
-
28
-
-
78649615697
-
Increased levels of hypoxia-inducible factor-1alpha are associated with Bcl-xL expression, tumor apoptosis, and clinical outcome in chondrosarcoma
-
Chen C, Zhou H, Wei F, Jiang L, Liu X, et al (2011) Increased levels of hypoxia-inducible factor-1alpha are associated with Bcl-xL expression, tumor apoptosis, and clinical outcome in chondrosarcoma. J Orthop Res 29: 143-151.
-
(2011)
J Orthop Res
, vol.29
, pp. 143-151
-
-
Chen, C.1
Zhou, H.2
Wei, F.3
Jiang, L.4
Liu, X.5
-
29
-
-
80051545127
-
Association of elevated HIF-2alpha levels with low Beclin 1 expression and poor prognosis in patients with chondrosarcoma
-
Chen C, Ma Q, Ma X, Liu Z, Liu X (2001) Association of elevated HIF-2alpha levels with low Beclin 1 expression and poor prognosis in patients with chondrosarcoma. Ann Surg Oncol 18: 2364-2372.
-
(2001)
Ann Surg Oncol
, vol.18
, pp. 2364-2372
-
-
Chen, C.1
Ma, Q.2
Ma, X.3
Liu, Z.4
Liu, X.5
-
30
-
-
84866927512
-
Coordinated action of hypoxia-inducible factor-1alpha and beta-catenin in androgen receptor signaling
-
Mitani T, Harada N, Nakano Y, Inui H, Yamaji R (2012). Coordinated action of hypoxia-inducible factor-1alpha and beta-catenin in androgen receptor signaling. J Biol Chem 287: 33594-33606.
-
(2012)
J Biol Chem
, vol.287
, pp. 33594-33606
-
-
Mitani, T.1
Harada, N.2
Nakano, Y.3
Inui, H.4
Yamaji, R.5
-
31
-
-
1542293250
-
Chondrosarcoma
-
Fletcher CDM, Unni KK, Mertens F, eds. Lyon: IARC Press
-
Bertoni F, Bacchini P, Hogendoorn PCW (2002). Chondrosarcoma. In: Fletcher CDM, Unni KK, Mertens F, eds. World Health Organisation classification of tumours: pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press 247-51.
-
(2002)
World Health Organisation Classification of Tumours: Pathology and Genetics of Tumours of Soft Tissue and Bone
, pp. 247-251
-
-
Bertoni, F.1
Bacchini, P.2
Hogendoorn, P.C.W.3
-
32
-
-
84861206346
-
Advanced bone formation in mice with a dominant-negative mutation in the thyroid hormone receptor beta gene due to activation of Wnt/beta-catenin protein signaling
-
O'Shea PJ, Kim DW, Logan JG, Davis S, Walker RL, et al (2012) Advanced bone formation in mice with a dominant-negative mutation in the thyroid hormone receptor beta gene due to activation of Wnt/beta-catenin protein signaling. J Biol Chem 287: 17812-17822.
-
(2012)
J Biol Chem
, vol.287
, pp. 17812-17822
-
-
O'Shea, P.J.1
Kim, D.W.2
Logan, J.G.3
Davis, S.4
Walker, R.L.5
-
33
-
-
84861401445
-
Expression of dickkopf-1 and beta-catenin related to the prognosis of breast cancer patients with triple negative phenotype
-
Xu WH, Liu ZB, Yang C, Qin W, Shao ZM (2012) Expression of dickkopf-1 and beta-catenin related to the prognosis of breast cancer patients with triple negative phenotype. PLoS One 7: e37624.
-
(2012)
PLoS One
, vol.7
-
-
Xu, W.H.1
Liu, Z.B.2
Yang, C.3
Qin, W.4
Shao, Z.M.5
-
34
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
DOI 10.1038/nrc2389, PII NRC2389
-
Klaus A, Birchmeier W (2008) Wnt signalling and its impact on development and cancer. Nat Rev Cancer. 2008;8: 387-398. (Pubitemid 351589714)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.5
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
35
-
-
33745719463
-
Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling
-
DOI 10.1002/path.2008
-
Hameetman L, Rozeman LB, Lombaerts M, Oosting J, Taminiau AH, et al (2006). Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling. J Pathol 209: 501-511. (Pubitemid 44194565)
-
(2006)
Journal of Pathology
, vol.209
, Issue.4
, pp. 501-511
-
-
Hameetman, L.1
Rozeman, L.B.2
Lombaerts, M.3
Oosting, J.4
Taminiau, A.H.M.5
Cleton-Jansen, A.-M.6
Bovee, J.V.M.G.7
Hogendoorn, P.C.W.8
-
36
-
-
62549142642
-
Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma
-
Schrage YM, Hameetman L, Szuhai K, Cleton-Jansen AM, Taminiau AH, et al (2009). Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma. Am J Pathol 174: 979-988.
-
(2009)
Am J Pathol
, vol.174
, pp. 979-988
-
-
Schrage, Y.M.1
Hameetman, L.2
Szuhai, K.3
Cleton-Jansen, A.M.4
Taminiau, A.H.5
-
37
-
-
84877030479
-
Nuclear beta-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer
-
Li XQ, Yang XL, Zhang G, Wu SP, Deng XB, et al (2013). Nuclear beta-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer. J Transl Med 11: 114.
-
(2013)
J Transl Med
, vol.11
, pp. 114
-
-
Li, X.Q.1
Yang, X.L.2
Zhang, G.3
Wu, S.P.4
Deng, X.B.5
|