The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesis

Cell Death and Disease

Volumn 5, Issue , 2014, Pages

  Ciaffardini, F ^a   Nicolai, S ^a   Caputo, M ^a   Canu, G ^a   Paccosi, E ^a   Costantino, M ^a   Frontini, M ^b   Balajee, A S ^c   Proietti De Santis, L ^a  

^a UNIVERSITY OF TUSCIA   (Italy)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NewYork Presbyterian Hospital   (United States)

Author keywords

chromatin remodeling complexes; Cockayne syndrome; neuritogenesis; neurodegeneration; neurogenesis; transcription complex assembly and progeroid syndromes

Indexed keywords

BETA TUBULIN; COCKAYNE SYNDROME B PROTEIN; HISTONE DEACETYLASE 1; MICROTUBULE ASSOCIATED PROTEIN 2; PROTEIN; RNA POLYMERASE; RNA POLYMERASE II; UNCLASSIFIED DRUG; DNA HELICASE; ERCC6 PROTEIN, HUMAN; MAP2 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; COCKAYNE SYNDROME; IMMUNOFLUORESCENCE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEURITE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; UPREGULATION; ADULT; CELL LINE; CYTOLOGY; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

ADULT; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA HELICASES; DNA REPAIR ENZYMES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; NEURAL STEM CELLS; NEURITES; NEUROGENESIS; TRANSCRIPTION, GENETIC;

EID: 84925545191     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.228     Document Type: Article

References (59)

1. Weidenheim KM, Dickson DW, Rapin I. Neuropathology of Cockayne syndrome: evidence for impaired development, premature aging, and neurodegeneration. Mech Ageing Dev 2009; 130: 619-636.
2. Laugel V, Dalloz C, Durand M, Sauvanaud F, Kristensen U, Vincent MC et al. Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome. Hum Mutat 2010; 31: 113-126.
3. Natale V. A comprehensive description of the severity groups in Cockayne syndrome. Am J Med Genet 2011; 155A: 1081-1095.
4. Henning KA, Li L, Iyer N, McDaniel LD, Reagan MS, Legerski R et al. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 1995; 82: 555-564.
5. Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 1992; 71: 939-953.
6. Lehmann AR. Three complementation groups in Cockayne syndrome. Mutat Res 1982; 106: 347-356.
7. Venema J, Mullenders LH, Natarajan AT, van Zeeland AA, Mayne LV. The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc Natl Acad Sci USA 1990; 87: 4707-4711.
8. Licht CL, Stevnsner T, Bohr VA. Cockayne syndrome group B cellular and biochemical functions. Am J Hum Genet 2003; 73: 1217-1239.
9. Laine JP, Egly JM. When transcription and repair meet: a complex system. Trends Genet 2006; 22: 430-436.
10. Sarasin A, Stary A. New insights for understanding the transcription-coupled repair pathway. DNA Repair (Amst) 2007; 6: 265-269.
11. Mayne LV, Lehmann AR. Failure of RNA synthesis to recover after UV irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum. Cancer Res 1982; 42: 1473-1478.
12. Balajee AS, Proietti-De-Santis L, Brosh RM, Selzer R, Bohr VA. Role of the ATPase domain of the Cockayne syndrome group B protein in UV induced apoptosis. Oncogene 2000; 19: 477-489.
13. Aamann MD, Muftuoglu M, Bohr VA, Stevnsner T. Multiple interaction partners for Cockayne syndrome proteins: implications for genome and transcriptome maintenance. Mech Ageing Dev 2013; 134: 212-224.
14. Caputo M, Frontini M, Velez-Cruz R, Nicolai S, Prantera G, Proietti-De-Santis L. The CSB repair factor is overexpressed in cancer cells, increased apoptosi resistence, and promotes tumor growth. DNA Repair 2013; 12: 293-299.
15. Brooks PJ. Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease. DNA Repair 2013; 12: 656-671.
16. Balajee AS, May A, Dianov GL, Friedberg EC, Bohr VA. Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc Natl Acad Sci USA 1997; 94: 4306-4311.
17. Selby CP, Sancar A. Cockayne syndrome group B protein enhances elongation by RNA polymerase II. Proc Natl Acad Sci USA 1997; 94: 11205-11209.
18. Tantin D, Kansal A, Carey M. Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes. Mol Cell Biol 1997; 17: 6803-6814.
19. van Gool AJ, van der Horst GT, Citterio E, Hoeijmakers JH. Cockayne syndrome: defective repair of transcription? EMBO J 1997; 16: 4155-4162.
20. Bradsher J, Auriol J, Proietti de Santis L, Iben S, Vonesch JL, Grummt I et al. CSB is a component of RNA pol I transcription. Mol Cell 2002; 10: 819-829.
21. Yuan X, Feng W, Imhof A, Grummt I, Zhou Y. Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a. Mol Cell 2007; 27: 585-595.
22. Brooks PJ, Cheng TF, Cooper L. Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage? DNA Repair 2008; 7: 834-848.
23. Proietti-De-Santis L, Drane P, Egly JM. Cockayne syndrome B protein regulates the transcriptional program after UV irradiation. EMBO J 2006; 25: 1915-1923.
24. Filippi S, Latini P, Frontini M, Palitti F, Egly JM, Proietti-De-Santis L. CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response. EMBO J 2008; 27: 2545-2556.
25. Frontini M, Proietti-De-Santis L. Cockayne syndrome B protein (CSB): linking p53, HIF-1 and p300 to robustness, lifespan, cancer and cell fate decisions. Cell Cycle 2009; 8: 693-696.
26. Newman JC, Bailey AD, Fan HY, Pavelitz T, Weiner AM. An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome. PLoS Genet 2008; 4: e1000031.
27. Velez-Cruz R, Egly JM. Cockayne syndrome group B (CSB) protein: at the crossroads of transcriptional networks. Mech Ageing Dev 2013; 134: 234-242.
28. Curtis MA, Kam M, Nannmark U, Anderson MF, Axell MZ, Wikkelso C et al. Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension. Science 2007; 315: 1243-1249.
29. Sanai N, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A. Comment on 'Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension'. Science 2007; 318: 393.
30. Tau GZ, Peterson BS. Normal development of brain circuits. Neuropsychopharmacology 2010; 35: 147-168.
31. Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M et al. Corridors of migrating neurons in the human brain and their decline during infancy. Nature 2011; 478: 382-386.
32. Bonfanti L, Peretto P. Adult neurogenesis in mammals - a theme with many variations. Eur J Neurosci 2011; 34: 930-950.
33. Spreen O, Risser AH, Edgell D. Developmental Neuropsychology. Oxford University press: New York, 1995.
34. Cunningham CC, Leclerc N, Flanagan LA, Lu M, Janmey PA, Losik KS. Microtubuleassociated protein 2c reorganizes both microtubules and microfilaments into distinct cytological structures in an actin-binding protein-280-deficient melanoma cell line. J Cell Biol 1997; 136: 845-857.
35. Tantin D. RNA polymerase II elongation complexes containing the Cockayne syndrome group B protein interact with a molecular complex containing the transcription factor IIH components xeroderma pigmentosum B and p62. J Biol Chem 1998; 273: 27794-27799.
36. Rigaut G, Shevchenko A, Rutz B, Wilm M, Mann M, Séraphin B. A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol 1999; 17: 1030-1032.
37. Rumpf C, Cipak L, Dudas A, Benko Z, Pozgajova M, Riedel CG et al. Casein kinase 1 is required for efficient removal of Rec8 during meiosis I. Cell Cycle 2010; 9: 2657-2662.
38. Rumpf C, Cipak L, Schleiffer A, Pidoux A, Mechtler K, Tolić-Nørrelykke IM et al. Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4. Cell Cycle 2010; 9: 3997-4004.
39. Cipak L, Spirek M, Novatchkova M, Chen Z, Rumpf C, Lugmayr W et al. An improved strategy for tandem affinity purification-tagging of Schizosaccharomyces pombe genes. Proteomics 2009; 9: 4825-4828.
40. Gregan J, Riedel CG, Petronczki M, Cipak L, Rumpf C, Poser I et al. Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc 2007; 2: 1145-1151.
41. Ho L, Crabtree GR. Chromatin remodelling during development. Nature 2010; 463: 474-484.
42. Hong EJ, West AE, Greenberg ME. Transcriptional control of cognitive development. Curr Opin Neurobiol 2005; 15: 21-28.
43. Hsieh J, Gage FH. Chromatin remodeling in neural development and plasticity. Curr Opin Cell Biol 2005; 17: 664-671.
44. Goldberg AD, Allis CD, Bernstein E. Epigenetics: a landscape takes shape. Cell 2007; 128: 635-638.
45. Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR. Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev 1996; 10: 2117-2130.
46. Wu JI, Lessard J, Olave IA, Qiu Z, Ghosh A, Graef IA et al. Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 2007; 56: 94-108.
47. Chatterjee S, Mizar P, Cassel R, Neidl R, Selvi BR, Mohankrishna DV et al. A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice. J Neurosci 2013; 33: 10698-10712.
48. Laposa RR, Huang EJ, Cleaver JE. Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice. Proc Natl Acad Sci USA 2007; 104: 1389-1394.
49. Brace LE, Vose SC, Vargas DF, Zhao S, Wang XP, Mitchell JR. Lifespan extension by dietary intervention in a mouse model of Cockayne syndrome uncouples early postnatal development from segmental progeria. Aging Cell 2013; 12: 1144-1147.
50. Sacco R, Tamblyn L, Rajakulendran N, Bralha FN, Tropepe V, Laposa RR. Cockayne syndrome b maintains neural precursor function. DNA Repair (Amst) 2013; 12: 110-120.
51. Walton RM. Postnatal neurogenesis: of mice, men, and macaques. Vet Pathol 2012; 49: 155-165.
52. Yang Z, Ming GL, Song H. Postnatal neurogenesis in the human forebrain: from two migratory streams to dribbles. Cell Stem Cell 2011; 9: 385-386.
53. Feliciano DM, Bordey A. Newborn cortical neurons: only for neonates? Trends Neurosci 2013; 36: 51-61.
54. Robbins JH, Brumback RA, Mendiones M, Barrett SF, Carl JR, Cho S et al. Neurological disease in xeroderma pigmentosum. Documentation of a late onset type of the juvenile onset form. Brain 1991; 114: 1335-1361.
55. Przedborski S, Vila M, Jackson-Lewis V. Neurodegeneration: what is it and where are we? J Clin Invest 2003; 111: 3-10.
56. Guzy RD, Schumacker PT. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 2006; 91: 807-819.
57. Aamann MD, Sorensen MM, Hvitby C, Berquist BR, Muftuoglu M, Tian J et al. Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane. FASEB J 2010; 24: 2334-2346.
58. Scheibye-Knudsen M, Ramamoorthy M, Sykora P, Maynard S, Lin PC, Minor RK et al. Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J Exp Med 2012; 209: 855-869.
59. Berquist BR, Canugovi C, Sykora P, Wilson DM, Bohr VA. Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation. Nucleic Acids Res 2012; 40: 8392-8405.