메뉴 건너뛰기




Volumn 307, Issue 2, 2015, Pages 191-197

Cyclic mechanical strain induces TGFβ1-signalling in dermal fibroblasts embedded in a 3D collagen lattice

Author keywords

CTGF; Mechanoregulation; Skin fibroblast; Tension

Indexed keywords

COLLAGEN; COLLAGEN GEL; CONNECTIVE TISSUE GROWTH FACTOR; F ACTIN; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; CTGF PROTEIN, MOUSE; CULTURE MEDIUM; RNA; SMAD2 PROTEIN, MOUSE;

EID: 84925535592     PISSN: 03403696     EISSN: 1432069X     Source Type: Journal    
DOI: 10.1007/s00403-014-1514-2     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 0028328817 scopus 로고
    • An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
    • COI: 1:CAS:528:DyaK2cXmvFOhug%3D%3D, PID: 8179182
    • Abe M, Harpel JG, Metz CN, Nunes I, Loskutoff DJ, Rifkin DB (1994) An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 216(2):276–284
    • (1994) Anal Biochem , vol.216 , Issue.2 , pp. 276-284
    • Abe, M.1    Harpel, J.G.2    Metz, C.N.3    Nunes, I.4    Loskutoff, D.J.5    Rifkin, D.B.6
  • 2
    • 33847392947 scopus 로고    scopus 로고
    • New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma
    • COI: 1:CAS:528:DC%2BD2sXhtVehsr3M, PID: 17502044
    • Abraham DJ, Eckes B, Rajkumar V, Krieg T (2007) New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma. Curr Rheumatol Rep 9(2):136–143
    • (2007) Curr Rheumatol Rep , vol.9 , Issue.2 , pp. 136-143
    • Abraham, D.J.1    Eckes, B.2    Rajkumar, V.3    Krieg, T.4
  • 3
    • 0001297636 scopus 로고
    • Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro
    • COI: 1:CAS:528:DyaE1MXhvVCis7k%3D, PID: 286310
    • Bell E, Ivarsson B, Merrill C (1979) Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc Natl Acad Sci USA 76(3):1274–1278
    • (1979) Proc Natl Acad Sci USA , vol.76 , Issue.3 , pp. 1274-1278
    • Bell, E.1    Ivarsson, B.2    Merrill, C.3
  • 4
    • 78650916311 scopus 로고    scopus 로고
    • Cyclic mechanical stretch reduces myofibroblast differentiation of primary lung fibroblasts
    • COI: 1:CAS:528:DC%2BC3MXksFOqsw%3D%3D, PID: 21094632
    • Blaauboer ME, Smit TH, Hanemaaijer R, Stoop R, Everts V (2011) Cyclic mechanical stretch reduces myofibroblast differentiation of primary lung fibroblasts. Biochem Biophys Res Commun 404(1):23–27
    • (2011) Biochem Biophys Res Commun , vol.404 , Issue.1 , pp. 23-27
    • Blaauboer, M.E.1    Smit, T.H.2    Hanemaaijer, R.3    Stoop, R.4    Everts, V.5
  • 5
    • 78649739167 scopus 로고    scopus 로고
    • Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts—role of TGFbeta1 levels and RhoA activity
    • COI: 1:CAS:528:DC%2BC3cXhsF2jsL%2FK, PID: 20980390
    • Blumbach K, Zweers MC, Brunner G, Peters AS, Schmitz M, Schulz JN, Schild A, Denton CP, Sakai T, Fassler R, Krieg T, Eckes B (2010) Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts—role of TGFbeta1 levels and RhoA activity. J Cell Sci 123(Pt 22):3872–3883
    • (2010) J Cell Sci , vol.123 , pp. 3872-3883
    • Blumbach, K.1    Zweers, M.C.2    Brunner, G.3    Peters, A.S.4    Schmitz, M.5    Schulz, J.N.6    Schild, A.7    Denton, C.P.8    Sakai, T.9    Fassler, R.10    Krieg, T.11    Eckes, B.12
  • 6
    • 84883559642 scopus 로고    scopus 로고
    • In the beginning there were soft collagen-cell gels: towards better 3D connective tissue models?
    • COI: 1:CAS:528:DC%2BC3sXhtFOnsb%2FJ, PID: 23856376
    • Brown RA (2013) In the beginning there were soft collagen-cell gels: towards better 3D connective tissue models? Exp Cell Res 319(16):2460–2469
    • (2013) Exp Cell Res , vol.319 , Issue.16 , pp. 2460-2469
    • Brown, R.A.1
  • 7
    • 0031969588 scopus 로고    scopus 로고
    • Tensional homeostasis in dermal fibroblasts: mechanical responses to mechanical loading in three-dimensional substrates
    • COI: 1:CAS:528:DyaK1cXisVCju70%3D, PID: 9572477
    • Brown RA, Prajapati R, McGrouther DA, Yannas IV, Eastwood M (1998) Tensional homeostasis in dermal fibroblasts: mechanical responses to mechanical loading in three-dimensional substrates. J Cell Physiol 175(3):323–332
    • (1998) J Cell Physiol , vol.175 , Issue.3 , pp. 323-332
    • Brown, R.A.1    Prajapati, R.2    McGrouther, D.A.3    Yannas, I.V.4    Eastwood, M.5
  • 8
    • 58849106652 scopus 로고    scopus 로고
    • A tense situation: forcing tumour progression
    • COI: 1:CAS:528:DC%2BD1MXpsVeqtA%3D%3D, PID: 19165226
    • Butcher DT, Alliston T, Weaver VM (2009) A tense situation: forcing tumour progression. Nat Rev Cancer 9(2):108–122
    • (2009) Nat Rev Cancer , vol.9 , Issue.2 , pp. 108-122
    • Butcher, D.T.1    Alliston, T.2    Weaver, V.M.3
  • 9
    • 33746751471 scopus 로고    scopus 로고
    • Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins
    • COI: 1:CAS:528:DC%2BD28XovFynsLk%3D, PID: 16856934
    • Chaqour B, Goppelt-Struebe M (2006) Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins. FEBS J 273(16):3639–3649
    • (2006) FEBS J , vol.273 , Issue.16 , pp. 3639-3649
    • Chaqour, B.1    Goppelt-Struebe, M.2
  • 10
    • 0032730185 scopus 로고    scopus 로고
    • Regulation of extracellular matrix gene expression by mechanical stress
    • COI: 1:CAS:528:DyaK1MXotFans7s%3D, PID: 10601729
    • Chiquet M (1999) Regulation of extracellular matrix gene expression by mechanical stress. Matrix Biol 18(5):417–426
    • (1999) Matrix Biol , vol.18 , Issue.5 , pp. 417-426
    • Chiquet, M.1
  • 11
    • 44249117598 scopus 로고    scopus 로고
    • Looking older: fibroblast collapse and therapeutic implications
    • PID: 18490597
    • Fisher GJ, Varani J, Voorhees JJ (2008) Looking older: fibroblast collapse and therapeutic implications. Arch Dermatol 144(5):666–672
    • (2008) Arch Dermatol , vol.144 , Issue.5 , pp. 666-672
    • Fisher, G.J.1    Varani, J.2    Voorhees, J.J.3
  • 12
    • 65649132626 scopus 로고    scopus 로고
    • Scleroderma
    • COI: 1:CAS:528:DC%2BD1MXls1ShsLw%3D, PID: 19420368
    • Gabrielli A, Avvedimento EV, Krieg T (2009) Scleroderma. N Engl J Med 360(19):1989–2003
    • (2009) N Engl J Med , vol.360 , Issue.19 , pp. 1989-2003
    • Gabrielli, A.1    Avvedimento, E.V.2    Krieg, T.3
  • 13
    • 81355127217 scopus 로고    scopus 로고
    • Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-beta1
    • COI: 1:CAS:528:DC%2BC3MXhsFSjtb3E, PID: 22020089
    • Galie PA, Russell MW, Westfall MV, Stegemann JP (2012) Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-beta1. Exp Cell Res 318(1):75–84
    • (2012) Exp Cell Res , vol.318 , Issue.1 , pp. 75-84
    • Galie, P.A.1    Russell, M.W.2    Westfall, M.V.3    Stegemann, J.P.4
  • 14
    • 78049365986 scopus 로고    scopus 로고
    • Cell motility and mechanics in three-dimensional collagen matrices
    • COI: 1:CAS:528:DC%2BC3cXhsFCnur%2FI, PID: 19575667
    • Grinnell F, Petroll WM (2010) Cell motility and mechanics in three-dimensional collagen matrices. Annu Rev Cell Dev Biol 26:335–361
    • (2010) Annu Rev Cell Dev Biol , vol.26 , pp. 335-361
    • Grinnell, F.1    Petroll, W.M.2
  • 15
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • COI: 1:CAS:528:DC%2BD3MXntVGrt7w%3D, PID: 11553712
    • Hinz B, Celetta G, Tomasek JJ, Gabbiani G, Chaponnier C (2001) Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell 12(9):2730–2741
    • (2001) Mol Biol Cell , vol.12 , Issue.9 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 16
    • 78649383858 scopus 로고    scopus 로고
    • Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives
    • Hinz B, Gabbiani G (2010) Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives. F1000 Biol Rep 2:78
    • (2010) F1000 Biol Rep , vol.2 , pp. 78
    • Hinz, B.1    Gabbiani, G.2
  • 17
    • 79960637431 scopus 로고    scopus 로고
    • Dynamic molecular processes mediate cellular mechanotransduction
    • COI: 1:CAS:528:DC%2BC3MXpt1aqu7o%3D, PID: 21776077
    • Hoffman BD, Grashoff C, Schwartz MA (2011) Dynamic molecular processes mediate cellular mechanotransduction. Nature 475(7356):316–323
    • (2011) Nature , vol.475 , Issue.7356 , pp. 316-323
    • Hoffman, B.D.1    Grashoff, C.2    Schwartz, M.A.3
  • 18
    • 0035815683 scopus 로고    scopus 로고
    • CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling
    • COI: 1:CAS:528:DC%2BD3MXjvFCqtrs%3D, PID: 11152469
    • Holmes A, Abraham DJ, Sa S, Shiwen X, Black CM, Leask A (2001) CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling. J Biol Chem 276(14):10594–10601
    • (2001) J Biol Chem , vol.276 , Issue.14 , pp. 10594-10601
    • Holmes, A.1    Abraham, D.J.2    Sa, S.3    Shiwen, X.4    Black, C.M.5    Leask, A.6
  • 19
    • 0029996247 scopus 로고    scopus 로고
    • Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders
    • COI: 1:STN:280:DyaK287otlGmtA%3D%3D, PID: 8618012
    • Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Fujimoto M, Grotendorst GR, Takehara K (1996) Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J Invest Dermatol 106(4):729–733
    • (1996) J Invest Dermatol , vol.106 , Issue.4 , pp. 729-733
    • Igarashi, A.1    Nashiro, K.2    Kikuchi, K.3    Sato, S.4    Ihn, H.5    Fujimoto, M.6    Grotendorst, G.R.7    Takehara, K.8
  • 20
    • 70350771231 scopus 로고    scopus 로고
    • Cyclical cell stretching of skin-derived fibroblasts downregulates connective tissue growth factor (CTGF) production
    • COI: 1:CAS:528:DC%2BD1MXhsVOhurfO, PID: 19863391
    • Kanazawa Y, Nomura J, Yoshimoto S, Suzuki T, Kita K, Suzuki N, Ichinose M (2009) Cyclical cell stretching of skin-derived fibroblasts downregulates connective tissue growth factor (CTGF) production. Connect Tissue Res 50(5):323–329
    • (2009) Connect Tissue Res , vol.50 , Issue.5 , pp. 323-329
    • Kanazawa, Y.1    Nomura, J.2    Yoshimoto, S.3    Suzuki, T.4    Kita, K.5    Suzuki, N.6    Ichinose, M.7
  • 21
    • 0035965308 scopus 로고    scopus 로고
    • Fibroblasts in mechanically stressed collagen lattices assume a “synthetic” phenotype
    • COI: 1:CAS:528:DC%2BD3MXnt1yrtL0%3D, PID: 11468280
    • Kessler D, Dethlefsen S, Haase I, Plomann M, Hirche F, Krieg T, Eckes B (2001) Fibroblasts in mechanically stressed collagen lattices assume a “synthetic” phenotype. J Biol Chem 276(39):36575–36585
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36575-36585
    • Kessler, D.1    Dethlefsen, S.2    Haase, I.3    Plomann, M.4    Hirche, F.5    Krieg, T.6    Eckes, B.7
  • 22
    • 73549104820 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?
    • PID: 19156539
    • Leask A, Parapuram SK, Shi-Wen X, Abraham DJ (2009) Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease? J Cell Commun Signal 3(2):89–94
    • (2009) J Cell Commun Signal , vol.3 , Issue.2 , pp. 89-94
    • Leask, A.1    Parapuram, S.K.2    Shi-Wen, X.3    Abraham, D.J.4
  • 23
    • 34347402254 scopus 로고    scopus 로고
    • A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels
    • COI: 1:CAS:528:DC%2BD2sXnvVags7k%3D, PID: 17341683
    • Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ (2007) A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels. Faseb J 21(9):2064–2073
    • (2007) Faseb J , vol.21 , Issue.9 , pp. 2064-2073
    • Leung, L.Y.1    Tian, D.2    Brangwynne, C.P.3    Weitz, D.A.4    Tschumperlin, D.J.5
  • 26
    • 84863878959 scopus 로고    scopus 로고
    • Cross talk among TGF-beta signaling pathways, integrins, and the extracellular matrix
    • PID: 21900405
    • Munger JS, Sheppard D (2011) Cross talk among TGF-beta signaling pathways, integrins, and the extracellular matrix. Cold Spring Harb Perspect Biol 3(11):a005017
    • (2011) Cold Spring Harb Perspect Biol , vol.3 , Issue.11 , pp. 005017
    • Munger, J.S.1    Sheppard, D.2
  • 27
    • 29144531874 scopus 로고    scopus 로고
    • Mechanobiology in the third dimension
    • PID: 16341917
    • Pedersen JA, Swartz MA (2005) Mechanobiology in the third dimension. Ann Biomed Eng 33(11):1469–1490
    • (2005) Ann Biomed Eng , vol.33 , Issue.11 , pp. 1469-1490
    • Pedersen, J.A.1    Swartz, M.A.2
  • 28
    • 84871764248 scopus 로고    scopus 로고
    • Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGFbeta1 in dermal fibroblasts
    • COI: 1:CAS:528:DC%2BC38XhslWrsrbL, PID: 23078398
    • Peters AS, Brunner G, Blumbach K, Abraham DJ, Krieg T, Eckes B (2012) Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGFbeta1 in dermal fibroblasts. Exp Dermatol 21(10):765–770
    • (2012) Exp Dermatol , vol.21 , Issue.10 , pp. 765-770
    • Peters, A.S.1    Brunner, G.2    Blumbach, K.3    Abraham, D.J.4    Krieg, T.5    Eckes, B.6
  • 29
    • 77954317109 scopus 로고    scopus 로고
    • Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix
    • COI: 1:CAS:528:DC%2BC3cXotlChtbo%3D, PID: 20472565
    • Reed RK, Rubin K (2010) Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix. Cardiovasc Res 87(2):211–217
    • (2010) Cardiovasc Res , vol.87 , Issue.2 , pp. 211-217
    • Reed, R.K.1    Rubin, K.2
  • 30
    • 0029893807 scopus 로고    scopus 로고
    • Cyclic stretching force selectively up-regulates transforming growth factor-beta isoforms in cultured rat mesangial cells
    • COI: 1:CAS:528:DyaK28XktlCitrc%3D, PID: 8669477
    • Riser BL, Cortes P, Heilig C, Grondin J, Ladson-Wofford S, Patterson D, Narins RG (1996) Cyclic stretching force selectively up-regulates transforming growth factor-beta isoforms in cultured rat mesangial cells. Am J Pathol 148(6):1915–1923
    • (1996) Am J Pathol , vol.148 , Issue.6 , pp. 1915-1923
    • Riser, B.L.1    Cortes, P.2    Heilig, C.3    Grondin, J.4    Ladson-Wofford, S.5    Patterson, D.6    Narins, R.G.7
  • 31
    • 0030058699 scopus 로고    scopus 로고
    • Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1
    • COI: 1:CAS:528:DyaK28XovFSksA%3D%3D, PID: 8617200
    • Saharinen J, Taipale J, Keski-Oja J (1996) Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1. EMBO J 15(2):245–253
    • (1996) EMBO J , vol.15 , Issue.2 , pp. 245-253
    • Saharinen, J.1    Taipale, J.2    Keski-Oja, J.3
  • 32
    • 33646058254 scopus 로고    scopus 로고
    • Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain
    • COI: 1:CAS:528:DC%2BD28Xjs1ajtr0%3D, PID: 16448650
    • Sarasa-Renedo A, Tunc-Civelek V, Chiquet M (2006) Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain. Exp Cell Res 312(8):1361–1370
    • (2006) Exp Cell Res , vol.312 , Issue.8 , pp. 1361-1370
    • Sarasa-Renedo, A.1    Tunc-Civelek, V.2    Chiquet, M.3
  • 33
    • 79952598024 scopus 로고    scopus 로고
    • Integrins and extracellular matrix in mechanotransduction
    • COI: 1:CAS:528:DC%2BC3MXhsFKqt7Y%3D, PID: 21084386
    • Schwartz MA (2010) Integrins and extracellular matrix in mechanotransduction. Cold Spring Harb Perspect Biol 2(12):a005066
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , Issue.12 , pp. 005066
    • Schwartz, M.A.1
  • 34
    • 79959250326 scopus 로고    scopus 로고
    • Springer TA latent TGF-beta structure and activation
    • COI: 1:CAS:528:DC%2BC3MXnsFOrt7k%3D, PID: 21677751
    • Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA (2011) Latent TGF-beta structure and activation. Nature 474(7351):343–349
    • (2011) Nature , vol.474 , Issue.7351 , pp. 343-349
    • Shi, M.1    Zhu, J.2    Wang, R.3    Chen, X.4    Mi, L.5    Walz, T.6
  • 35
    • 33746891890 scopus 로고    scopus 로고
    • The primary cilium as the cell’s antenna: signaling at a sensory organelle
    • COI: 1:CAS:528:DC%2BD28Xnsl2htrg%3D, PID: 16888132
    • Singla V, Reiter JF (2006) The primary cilium as the cell’s antenna: signaling at a sensory organelle. Science 313(5787):629–633
    • (2006) Science , vol.313 , Issue.5787 , pp. 629-633
    • Singla, V.1    Reiter, J.F.2
  • 37
    • 0036277026 scopus 로고    scopus 로고
    • Myofibroblasts and mechano-regulation of connective tissue remodelling
    • COI: 1:CAS:528:DC%2BD38XjsFOgsbw%3D, PID: 11988769
    • Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA (2002) Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3(5):349–363
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.5 , pp. 349-363
    • Tomasek, J.J.1    Gabbiani, G.2    Hinz, B.3    Chaponnier, C.4    Brown, R.A.5
  • 38
    • 0021234218 scopus 로고
    • Analysis of the role of microfilaments and microtubules in acquisition of bipolarity and elongation of fibroblasts in hydrated collagen gels
    • COI: 1:CAS:528:DyaL2cXlt1yjtr4%3D, PID: 6146628
    • Tomasek JJ, Hay ED (1984) Analysis of the role of microfilaments and microtubules in acquisition of bipolarity and elongation of fibroblasts in hydrated collagen gels. J Cell Biol 99(2):536–549
    • (1984) J Cell Biol , vol.99 , Issue.2 , pp. 536-549
    • Tomasek, J.J.1    Hay, E.D.2
  • 39
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: a prototypic multisystem fibrotic disorder
    • COI: 1:CAS:528:DC%2BD2sXis12htrw%3D, PID: 17332883
    • Varga J, Abraham D (2007) Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 117(3):557–567
    • (2007) J Clin Invest , vol.117 , Issue.3 , pp. 557-567
    • Varga, J.1    Abraham, D.2
  • 40
    • 18744371941 scopus 로고    scopus 로고
    • Early responses to mechanical load in tendon: role for calcium signaling, gap junctions and intercellular communication
    • COI: 1:CAS:528:DC%2BD2MXkvVWhtb4%3D, PID: 15788873
    • Wall ME, Banes AJ (2005) Early responses to mechanical load in tendon: role for calcium signaling, gap junctions and intercellular communication. J Musculoskelet Neuronal Interact 5(1):70–84
    • (2005) J Musculoskelet Neuronal Interact , vol.5 , Issue.1 , pp. 70-84
    • Wall, M.E.1    Banes, A.J.2
  • 41
    • 0010275044 scopus 로고    scopus 로고
    • Rheology of polymers near liquid–solid transitions
    • COI: 1:CAS:528:DyaK2sXmslGitbo%3D
    • Winter HH, Mours M (1997) Rheology of polymers near liquid–solid transitions. Adv Polym Sci 134:165–234
    • (1997) Adv Polym Sci , vol.134 , pp. 165-234
    • Winter, H.H.1    Mours, M.2
  • 42
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix
    • COI: 1:CAS:528:DC%2BD2sXhsVOgtL%2FL, PID: 18086923
    • Wipff PJ, Rifkin DB, Meister JJ, Hinz B (2007) Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol 179(6):1311–1323
    • (2007) J Cell Biol , vol.179 , Issue.6 , pp. 1311-1323
    • Wipff, P.J.1    Rifkin, D.B.2    Meister, J.J.3    Hinz, B.4
  • 43
    • 0141750631 scopus 로고    scopus 로고
    • Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes
    • COI: 1:CAS:528:DC%2BD3sXnvVersLo%3D, PID: 14555274
    • Wong M, Siegrist M, Goodwin K (2003) Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes. Bone 33(4):685–693
    • (2003) Bone , vol.33 , Issue.4 , pp. 685-693
    • Wong, M.1    Siegrist, M.2    Goodwin, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.