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Volumn 54, Issue 4, 2015, Pages 359-370

Placental Transfer of Antidepressant Medications: Implications for Postnatal Adaptation Syndrome

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; DULOXETINE; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; NORTRIPTYLINE; PAROXETINE; SERTRALINE; TRAZODONE; VENLAFAXINE;

EID: 84925535391     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.1007/s40262-014-0233-3     Document Type: Review
Times cited : (69)

References (70)
  • 2
    • 84891629587 scopus 로고    scopus 로고
    • Perinatal mental illness: definition, description and aetiology
    • PID: 24140480
    • O’Hara MW, Wisner KL. Perinatal mental illness: definition, description and aetiology. Best Pract Res Clin Obstet Gynaecol. 2014;28:3–12.
    • (2014) Best Pract Res Clin Obstet Gynaecol , vol.28 , pp. 3-12
    • O’Hara, M.W.1    Wisner, K.L.2
  • 7
    • 84872171001 scopus 로고    scopus 로고
    • Antidepressant use in pregnancy: a critical review focused on risks and controversies
    • COI: 1:CAS:528:DC%2BC3sXjslKjt70%3D, PID: 23240634
    • Byatt N, Deligiannidis KM, Freeman MP. Antidepressant use in pregnancy: a critical review focused on risks and controversies. Acta Psychiatr Scand. 2013;127:94–114.
    • (2013) Acta Psychiatr Scand , vol.127 , pp. 94-114
    • Byatt, N.1    Deligiannidis, K.M.2    Freeman, M.P.3
  • 8
    • 84909594522 scopus 로고    scopus 로고
    • Neonatal adaptation in infants prenatally exposed to antidepressants—clinical monitoring using neonatal abstinence score
    • PID: 25365553
    • Forsberg L, Naver L, Gustafsson LL, Wide K. Neonatal adaptation in infants prenatally exposed to antidepressants—clinical monitoring using neonatal abstinence score. PLoS One. 2014;9:e111327.
    • (2014) PLoS One , vol.9 , pp. e111327
    • Forsberg, L.1    Naver, L.2    Gustafsson, L.L.3    Wide, K.4
  • 9
    • 18644382386 scopus 로고    scopus 로고
    • Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications
    • COI: 1:CAS:528:DC%2BD2MXktlals7w%3D, PID: 15900008
    • Moses-Kolko EL, Bogen D, Perel J, Bregar A, Uhl K, Levin B, Wisner KL. Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications. JAMA. 2005;293:2372–83.
    • (2005) JAMA , vol.293 , pp. 2372-2383
    • Moses-Kolko, E.L.1    Bogen, D.2    Perel, J.3    Bregar, A.4    Uhl, K.5    Levin, B.6    Wisner, K.L.7
  • 10
    • 84891631647 scopus 로고    scopus 로고
    • The use of antidepressant medication in pregnancy
    • PID: 24211026
    • Ray S, Stowe ZN. The use of antidepressant medication in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2014;28:71–83.
    • (2014) Best Pract Res Clin Obstet Gynaecol , vol.28 , pp. 71-83
    • Ray, S.1    Stowe, Z.N.2
  • 11
    • 84866502152 scopus 로고    scopus 로고
    • Current toxicological aspects on drug and chemical transport and metabolism across the human placental barrier
    • COI: 1:CAS:528:DC%2BC38XhtlGqs77J, PID: 22780574
    • Giaginis C, Theocharis S, Tsantili-Kakoulidou A. Current toxicological aspects on drug and chemical transport and metabolism across the human placental barrier. Expert Opin Drug Metab Toxicol. 2012;8:1263–75.
    • (2012) Expert Opin Drug Metab Toxicol , vol.8 , pp. 1263-1275
    • Giaginis, C.1    Theocharis, S.2    Tsantili-Kakoulidou, A.3
  • 12
    • 33846207538 scopus 로고    scopus 로고
    • Active transport across the human placenta: impact on drug efficacy and toxicity
    • COI: 1:CAS:528:DC%2BD28XpsVaktA%3D%3D, PID: 16863468
    • Evseenko D, Paxton JW, Keelan JA. Active transport across the human placenta: impact on drug efficacy and toxicity. Expert Opin Drug Metab Toxicol. 2006;2:51–69.
    • (2006) Expert Opin Drug Metab Toxicol , vol.2 , pp. 51-69
    • Evseenko, D.1    Paxton, J.W.2    Keelan, J.A.3
  • 13
    • 3042725709 scopus 로고    scopus 로고
    • Drug transfer and metabolism by the human placenta
    • COI: 1:CAS:528:DC%2BD2cXlvFOlt7g%3D, PID: 15170365
    • Syme MR, Paxton JW, Keelan JA. Drug transfer and metabolism by the human placenta. Clin Pharmacokinet. 2004;43:487–514.
    • (2004) Clin Pharmacokinet , vol.43 , pp. 487-514
    • Syme, M.R.1    Paxton, J.W.2    Keelan, J.A.3
  • 14
    • 36749058980 scopus 로고    scopus 로고
    • The emerging importance of transporter proteins in the psychopharmacological treatment of the pregnant patient
    • COI: 1:CAS:528:DC%2BD2sXhtlyitbnM, PID: 18058331
    • Wang JS, Newport DJ, Stowe ZN, Donovan JL, Pennell PB, DeVane CL. The emerging importance of transporter proteins in the psychopharmacological treatment of the pregnant patient. Drug Metab Rev. 2007;39:723–46.
    • (2007) Drug Metab Rev , vol.39 , pp. 723-746
    • Wang, J.S.1    Newport, D.J.2    Stowe, Z.N.3    Donovan, J.L.4    Pennell, P.B.5    DeVane, C.L.6
  • 15
    • 33750042578 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of psychoactive drugs during pregnancy in the genomic era: challenges and opportunities
    • PID: 16785271
    • DeVane CL, Stowe ZN, Donovan JL, Newport DJ, Pennell PB, Ritchie JC, et al. Therapeutic drug monitoring of psychoactive drugs during pregnancy in the genomic era: challenges and opportunities. J Psychopharmacol. 2006;20:54–9.
    • (2006) J Psychopharmacol , vol.20 , pp. 54-59
    • DeVane, C.L.1    Stowe, Z.N.2    Donovan, J.L.3    Newport, D.J.4    Pennell, P.B.5    Ritchie, J.C.6
  • 16
    • 84859917093 scopus 로고    scopus 로고
    • Sertraline alters multidrug resistance phosphoglycoprotein activity in the mouse placenta and fetal blood–brain barrier
    • COI: 1:CAS:528:DC%2BC38Xos1OrtbY%3D, PID: 22510699
    • Bhuiyan M, Petropoulos S, Gibb W, Matthews SG. Sertraline alters multidrug resistance phosphoglycoprotein activity in the mouse placenta and fetal blood–brain barrier. Reprod Sci. 2012;19:407–15.
    • (2012) Reprod Sci , vol.19 , pp. 407-415
    • Bhuiyan, M.1    Petropoulos, S.2    Gibb, W.3    Matthews, S.G.4
  • 17
    • 79956306873 scopus 로고    scopus 로고
    • Exposing fetal drug exposure
    • COI: 1:CAS:528:DC%2BC3MXmtlagtrs%3D, PID: 21593755
    • DeVane L, Goetzl LM, Ramamoorthy S. Exposing fetal drug exposure. Clin Pharmacol Ther. 2011;89:786–8.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 786-788
    • DeVane, L.1    Goetzl, L.M.2    Ramamoorthy, S.3
  • 18
    • 77957122945 scopus 로고    scopus 로고
    • The role of the placenta in fetal exposure to xenobiotics: importance of membrane transporters and human models for transfer studies
    • COI: 1:CAS:528:DC%2BC3cXht1eisLvI, PID: 20606001
    • Prouillac C, Lecoeur S. The role of the placenta in fetal exposure to xenobiotics: importance of membrane transporters and human models for transfer studies. Drug Metab Dispos. 2010;38:1623–35.
    • (2010) Drug Metab Dispos , vol.38 , pp. 1623-1635
    • Prouillac, C.1    Lecoeur, S.2
  • 19
    • 0030602864 scopus 로고    scopus 로고
    • Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy
    • COI: 1:CAS:528:DyaK28Xkt1KrtLs%3D, PID: 8694864
    • Hakkola J, Raunio H, Purkunen R, Pelkonen O, Saarikoski S, Cresteil T, et al. Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy. Biochem Pharmacol. 1996;52:379–83.
    • (1996) Biochem Pharmacol , vol.52 , pp. 379-383
    • Hakkola, J.1    Raunio, H.2    Purkunen, R.3    Pelkonen, O.4    Saarikoski, S.5    Cresteil, T.6
  • 20
    • 0030030817 scopus 로고    scopus 로고
    • Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta
    • COI: 1:CAS:528:DyaK28XhtlOgurw%3D, PID: 8619884
    • Hakkola J, Pasanen M, Hukkanen J, Pelkonen O, Maenpaa J, Edwards RJ, et al. Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta. Biochem Pharmacol. 1996;51:403–11.
    • (1996) Biochem Pharmacol , vol.51 , pp. 403-411
    • Hakkola, J.1    Pasanen, M.2    Hukkanen, J.3    Pelkonen, O.4    Maenpaa, J.5    Edwards, R.J.6
  • 21
    • 0041922374 scopus 로고    scopus 로고
    • Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR
    • COI: 1:CAS:528:DC%2BD3sXktF2qurc%3D, PID: 12772594
    • Nishimura M, Yaguti H, Yoshitsugu H, Naito S, Satoh T. Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR. Yakugaku Zasshi. 2003;123:369–75.
    • (2003) Yakugaku Zasshi , vol.123 , pp. 369-375
    • Nishimura, M.1    Yaguti, H.2    Yoshitsugu, H.3    Naito, S.4    Satoh, T.5
  • 22
    • 0032934670 scopus 로고    scopus 로고
    • The expression and regulation of drug metabolism in human placenta
    • COI: 1:CAS:528:DyaK1MXjs1ehtLc%3D, PID: 10837748
    • Pasanen M. The expression and regulation of drug metabolism in human placenta. Adv Drug Deliv Rev. 1999;38:81–97.
    • (1999) Adv Drug Deliv Rev , vol.38 , pp. 81-97
    • Pasanen, M.1
  • 23
    • 84907918836 scopus 로고    scopus 로고
    • Metabolism and disposition of bupropion in pregnant baboons (Papio cynocephalus)
    • COI: 1:CAS:528:DC%2BC2cXhs12jsb%2FJ, PID: 25097227
    • Rytting E, Wang X, Vernikovskaya DI, Zhan Y, Bauer C, Abdel-Rahman SM, et al. Metabolism and disposition of bupropion in pregnant baboons (Papio cynocephalus). Drug Metab Dispos. 2014;42:1773–9.
    • (2014) Drug Metab Dispos , vol.42 , pp. 1773-1779
    • Rytting, E.1    Wang, X.2    Vernikovskaya, D.I.3    Zhan, Y.4    Bauer, C.5    Abdel-Rahman, S.M.6
  • 26
    • 0037384041 scopus 로고    scopus 로고
    • Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation
    • COI: 1:CAS:528:DC%2BD3sXjtFWntb8%3D, PID: 12709723
    • Heikkinen T, Ekblad U, Palo P, Laine K. Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation. Clin Pharmacol Ther. 2003;73:330–7.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 330-337
    • Heikkinen, T.1    Ekblad, U.2    Palo, P.3    Laine, K.4
  • 27
    • 0344110152 scopus 로고    scopus 로고
    • Pharmacokinetics of selective serotonin reuptake inhibitors
    • COI: 1:CAS:528:DyaK1MXnvFeltLo%3D, PID: 10674711
    • Hiemke C, Hartter S. Pharmacokinetics of selective serotonin reuptake inhibitors. Pharmacol Ther. 2000;85:11–28.
    • (2000) Pharmacol Ther , vol.85 , pp. 11-28
    • Hiemke, C.1    Hartter, S.2
  • 28
    • 0021929838 scopus 로고
    • Pharmacokinetics of imipramine and its major metabolites in pregnant rats and their fetuses following a single dose
    • COI: 1:CAS:528:DyaL2MXkvFyhu7Y%3D, PID: 2863107
    • DeVane CL, Simpkins JW. Pharmacokinetics of imipramine and its major metabolites in pregnant rats and their fetuses following a single dose. Drug Metab Dispos. 1985;13:438–42.
    • (1985) Drug Metab Dispos , vol.13 , pp. 438-442
    • DeVane, C.L.1    Simpkins, J.W.2
  • 29
    • 44849088194 scopus 로고    scopus 로고
    • Changes in antidepressant metabolism and dosing across pregnancy and early postpartum
    • COI: 1:CAS:528:DC%2BD1cXmtFShtrw%3D, PID: 18426260
    • Sit DK, Perel JM, Helsel JC, Wisner KL. Changes in antidepressant metabolism and dosing across pregnancy and early postpartum. J Clin Psychiatry. 2008;69:652–8.
    • (2008) J Clin Psychiatry , vol.69 , pp. 652-658
    • Sit, D.K.1    Perel, J.M.2    Helsel, J.C.3    Wisner, K.L.4
  • 30
    • 84873019368 scopus 로고    scopus 로고
    • Fetal serotonin reuptake inhibitor antidepressant exposure: maternal and fetal factors
    • PID: 23073029
    • Shea AK, Oberlander TF, Rurak D. Fetal serotonin reuptake inhibitor antidepressant exposure: maternal and fetal factors. Can J Psychiatry. 2012;57:523–9.
    • (2012) Can J Psychiatry , vol.57 , pp. 523-529
    • Shea, A.K.1    Oberlander, T.F.2    Rurak, D.3
  • 31
    • 0030735733 scopus 로고    scopus 로고
    • Metabolism of the tricyclic antidepressant amitriptyline by cDNA-expressed human cytochrome P450 enzymes
    • COI: 1:CAS:528:DyaK2sXntlaqsb0%3D, PID: 9399333
    • Olesen OV, Linnet K. Metabolism of the tricyclic antidepressant amitriptyline by cDNA-expressed human cytochrome P450 enzymes. Pharmacology. 1997;55:235–43.
    • (1997) Pharmacology , vol.55 , pp. 235-243
    • Olesen, O.V.1    Linnet, K.2
  • 32
    • 80053903085 scopus 로고    scopus 로고
    • Risk assessment of accidental nortriptyline poisoning: the importance of cytochrome P450 for nortriptyline elimination investigated using a population-based pharmacokinetic simulator
    • COI: 1:CAS:528:DC%2BC3MXht12rt7bM, PID: 21854846
    • Jornil J, Jensen KG, Larsen F, Linnet K. Risk assessment of accidental nortriptyline poisoning: the importance of cytochrome P450 for nortriptyline elimination investigated using a population-based pharmacokinetic simulator. Eur J Pharm Sci. 2011;44:265–72.
    • (2011) Eur J Pharm Sci , vol.44 , pp. 265-272
    • Jornil, J.1    Jensen, K.G.2    Larsen, F.3    Linnet, K.4
  • 33
    • 77950350248 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response
    • COI: 1:CAS:528:DC%2BC3cXkvVOitbw%3D, PID: 20350136
    • Tsai MH, Lin KM, Hsiao MC, Shen WW, Lu ML, Tang HS, et al. Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response. Pharmacogenomics. 2010;11:537–46.
    • (2010) Pharmacogenomics , vol.11 , pp. 537-546
    • Tsai, M.H.1    Lin, K.M.2    Hsiao, M.C.3    Shen, W.W.4    Lu, M.L.5    Tang, H.S.6
  • 34
    • 1942531624 scopus 로고    scopus 로고
    • Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes
    • COI: 1:CAS:528:DC%2BD2cXksVWlsb8%3D, PID: 15083067
    • Hesse LM, He P, Krishnaswamy S, Hao Q, Hogan K, von Moltke LL, et al. Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes. Pharmacogenetics. 2004;14:225–38.
    • (2004) Pharmacogenetics , vol.14 , pp. 225-238
    • Hesse, L.M.1    He, P.2    Krishnaswamy, S.3    Hao, Q.4    Hogan, K.5    von Moltke, L.L.6
  • 35
    • 0031795570 scopus 로고    scopus 로고
    • Trazodone is metabolized to m-chlorophenylpiperazine by CYP3A4 from human sources
    • COI: 1:CAS:528:DyaK1cXjvFejsbw%3D, PID: 9616194
    • Rotzinger S, Fang J, Baker GB. Trazodone is metabolized to m-chlorophenylpiperazine by CYP3A4 from human sources. Drug Metab Dispos. 1998;26:572–5.
    • (1998) Drug Metab Dispos , vol.26 , pp. 572-575
    • Rotzinger, S.1    Fang, J.2    Baker, G.B.3
  • 36
    • 0030425332 scopus 로고    scopus 로고
    • The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways
    • COI: 1:CAS:528:DyaK28XjslGlu7w%3D, PID: 8667235
    • Nielsen KK, Flinois JP, Beaune P, Brosen K. The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways. J Pharmacol Exp Ther. 1996;277:1659–64.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1659-1664
    • Nielsen, K.K.1    Flinois, J.P.2    Beaune, P.3    Brosen, K.4
  • 37
    • 0035033019 scopus 로고    scopus 로고
    • Pharmacogenomics: unlocking the human genome for better drug therapy
    • COI: 1:CAS:528:DC%2BD3MXjsVaqsbg%3D, PID: 11264452
    • McLeod HL, Evans WE. Pharmacogenomics: unlocking the human genome for better drug therapy. Annu Rev Pharmacol Toxicol. 2001;41:101–21.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 101-121
    • McLeod, H.L.1    Evans, W.E.2
  • 38
    • 79959377520 scopus 로고    scopus 로고
    • The human placental perfusion model: a systematic review and development of a model to predict in vivo transfer of therapeutic drugs
    • COI: 1:CAS:528:DC%2BC3MXnvVaksbk%3D, PID: 21562489
    • Hutson JR, Garcia-Bournissen F, Davis A, Koren G. The human placental perfusion model: a systematic review and development of a model to predict in vivo transfer of therapeutic drugs. Clin Pharmacol Ther. 2011;90:67–76.
    • (2011) Clin Pharmacol Ther , vol.90 , pp. 67-76
    • Hutson, J.R.1    Garcia-Bournissen, F.2    Davis, A.3    Koren, G.4
  • 39
    • 0014564203 scopus 로고
    • The development of the baboon (Papio sp.) placenta during the fetal period of gestation
    • COI: 1:STN:280:DyaE3c%2Fjsl2ltw%3D%3D, PID: 4982040
    • Houston ML. The development of the baboon (Papio sp.) placenta during the fetal period of gestation. Am J Anat. 1969;126:17–29.
    • (1969) Am J Anat , vol.126 , pp. 17-29
    • Houston, M.L.1
  • 40
    • 0346608483 scopus 로고    scopus 로고
    • Pharmacokinetics of trazodone and its major metabolite m-chlorophenylpiperazine in plasma and brain of rats
    • COI: 1:CAS:528:DyaK1MXlvVOnur8%3D, PID: 11281966
    • DeVane CL, Boulton DW, Miller LF, Miller RL. Pharmacokinetics of trazodone and its major metabolite m-chlorophenylpiperazine in plasma and brain of rats. Int J Neuropsychopharmacol. 1999;2:17–23.
    • (1999) Int J Neuropsychopharmacol , vol.2 , pp. 17-23
    • DeVane, C.L.1    Boulton, D.W.2    Miller, L.F.3    Miller, R.L.4
  • 41
    • 0026357741 scopus 로고
    • Pharmacokinetic correlates of fetal drug exposure
    • COI: 1:CAS:528:DyaK3sXisVKksrY%3D, PID: 1754013
    • DeVane CL. Pharmacokinetic correlates of fetal drug exposure. NIDA Res Monogr. 1991;114:18–36.
    • (1991) NIDA Res Monogr , vol.114 , pp. 18-36
    • DeVane, C.L.1
  • 43
    • 0034669413 scopus 로고    scopus 로고
    • Amniotic fluid and umbilical cord blood concentrations of antidepressants in three women
    • COI: 1:CAS:528:DC%2BD3cXotVOju7g%3D, PID: 11082480
    • Hostetter A, Ritchie JC, Stowe ZN. Amniotic fluid and umbilical cord blood concentrations of antidepressants in three women. Biol Psychiatry. 2000;48:1032–4.
    • (2000) Biol Psychiatry , vol.48 , pp. 1032-1034
    • Hostetter, A.1    Ritchie, J.C.2    Stowe, Z.N.3
  • 44
    • 0842304216 scopus 로고    scopus 로고
    • Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep
    • COI: 1:CAS:528:DC%2BD2cXhsVWisbc%3D, PID: 14744943
    • Kim J, Riggs KW, Rurak DW. Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep. Drug Metab Dispos. 2004;32:212–21.
    • (2004) Drug Metab Dispos , vol.32 , pp. 212-221
    • Kim, J.1    Riggs, K.W.2    Rurak, D.W.3
  • 46
    • 0024595056 scopus 로고
    • Placental transfer and fetal distribution of fluoxetine in the rat
    • COI: 1:CAS:528:DyaL1MXktVSisbs%3D, PID: 2785300
    • Pohland RC, Byrd TK, Hamilton M, Koons JR. Placental transfer and fetal distribution of fluoxetine in the rat. Toxicol Appl Pharmacol. 1989;98:198–205.
    • (1989) Toxicol Appl Pharmacol , vol.98 , pp. 198-205
    • Pohland, R.C.1    Byrd, T.K.2    Hamilton, M.3    Koons, J.R.4
  • 47
    • 49949099705 scopus 로고    scopus 로고
    • Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities
    • PID: 18716672
    • Noorlander CW, Ververs FF, Nikkels PG, van Echteld CJ, Visser GH, Smidt MP. Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities. PLoS One. 2008;3:e2782.
    • (2008) PLoS One , vol.3 , pp. e2782
    • Noorlander, C.W.1    Ververs, F.F.2    Nikkels, P.G.3    van Echteld, C.J.4    Visser, G.H.5    Smidt, M.P.6
  • 48
    • 8844236997 scopus 로고    scopus 로고
    • Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose
    • COI: 1:CAS:528:DC%2BD2cXpslCqs7c%3D, PID: 15546675
    • Contrera JF, Matthews EJ, Kruhlak NL, Benz RD. Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose. Regul Toxicol Pharmacol. 2004;40:185–206.
    • (2004) Regul Toxicol Pharmacol , vol.40 , pp. 185-206
    • Contrera, J.F.1    Matthews, E.J.2    Kruhlak, N.L.3    Benz, R.D.4
  • 49
    • 0036754537 scopus 로고    scopus 로고
    • Transplacental transfer of citalopram, fluoxetine and their primary demethylated metabolites in isolated perfused human placenta
    • PID: 12269673
    • Heikkine T, Ekblad U, Laine K. Transplacental transfer of citalopram, fluoxetine and their primary demethylated metabolites in isolated perfused human placenta. BJOG. 2002;109:1003–8.
    • (2002) BJOG , vol.109 , pp. 1003-1008
    • Heikkine, T.1    Ekblad, U.2    Laine, K.3
  • 50
    • 0030860044 scopus 로고    scopus 로고
    • Potential fluoxetine chloride (Prozac) toxicity in a newborn
    • COI: 1:STN:280:DyaK2szms1GjsQ%3D%3D, PID: 9229710
    • Mhanna MJ, Bennet JB 2nd, Izatt SD. Potential fluoxetine chloride (Prozac) toxicity in a newborn. Pediatrics. 1997;100:158–9.
    • (1997) Pediatrics , vol.100 , pp. 158-159
    • Mhanna, M.J.1    Bennet, J.B.2    Izatt, S.D.3
  • 51
    • 0027485168 scopus 로고
    • Fluoxetine hydrochloride (Prozac) toxicity in a neonate
    • COI: 1:STN:280:DyaK2c%2FitFagsw%3D%3D, PID: 8414864
    • Spencer MJ. Fluoxetine hydrochloride (Prozac) toxicity in a neonate. Pediatrics. 1993;92:721–2.
    • (1993) Pediatrics , vol.92 , pp. 721-722
    • Spencer, M.J.1
  • 53
    • 4444374093 scopus 로고    scopus 로고
    • A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate
    • COI: 1:CAS:528:DC%2BD2cXmtlGmsrY%3D, PID: 15035694
    • Rampono J, Proud S, Hackett LP, Kristensen JH, Ilett KF. A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate. Int J Neuropsychopharmacol. 2004;7:329–34.
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 329-334
    • Rampono, J.1    Proud, S.2    Hackett, L.P.3    Kristensen, J.H.4    Ilett, K.F.5
  • 54
  • 55
    • 0028603653 scopus 로고
    • Pharmacogenetics and drug metabolism of newer antidepressant agents
    • PID: 7814357, (discussion 46–7)
    • Devane CL. Pharmacogenetics and drug metabolism of newer antidepressant agents. J Clin Psychiatry. 1994;55(Suppl):38–45 (discussion 46–7).
    • (1994) J Clin Psychiatry , vol.55 , pp. 38-45
    • Devane, C.L.1
  • 56
    • 68149178329 scopus 로고    scopus 로고
    • Placental transfer of SSRI and SNRI antidepressants and effects on the neonate
    • COI: 1:CAS:528:DC%2BD1MXnslWhtLw%3D, PID: 19452377
    • Rampono J, Simmer K, Ilett KF, Hackett LP, Doherty DA, Elliot R, et al. Placental transfer of SSRI and SNRI antidepressants and effects on the neonate. Pharmacopsychiatry. 2009;42:95–100.
    • (2009) Pharmacopsychiatry , vol.42 , pp. 95-100
    • Rampono, J.1    Simmer, K.2    Ilett, K.F.3    Hackett, L.P.4    Doherty, D.A.5    Elliot, R.6
  • 58
    • 79955923532 scopus 로고    scopus 로고
    • Duloxetine transfer across the placenta during pregnancy and into milk during lactation
    • PID: 21359876
    • Boyce PM, Hackett LP, Ilett KF. Duloxetine transfer across the placenta during pregnancy and into milk during lactation. Arch Womens Ment Health. 2011;14:169–72.
    • (2011) Arch Womens Ment Health , vol.14 , pp. 169-172
    • Boyce, P.M.1    Hackett, L.P.2    Ilett, K.F.3
  • 60
    • 0014206777 scopus 로고
    • Placental transfer of imipramine, a basic, lipid-soluble drug
    • COI: 1:STN:280:DyaF1c%2FgsFCrsw%3D%3D, PID: 6050751
    • Douglas BH, Hume AS. Placental transfer of imipramine, a basic, lipid-soluble drug. Am J Obstet Gynecol. 1967;99:573–5.
    • (1967) Am J Obstet Gynecol , vol.99 , pp. 573-575
    • Douglas, B.H.1    Hume, A.S.2
  • 61
    • 0014323801 scopus 로고
    • Placental transfer of desmethylimipramine
    • COI: 1:STN:280:DyaF1czhvVagsg%3D%3D, PID: 5690708
    • Hume AS, Douglas BH. Placental transfer of desmethylimipramine. Am J Obstet Gynecol. 1968;101:915–7.
    • (1968) Am J Obstet Gynecol , vol.101 , pp. 915-917
    • Hume, A.S.1    Douglas, B.H.2
  • 62
    • 0035105290 scopus 로고    scopus 로고
    • Transplacental transfer of amitriptyline and nortriptyline in isolated perfused human placenta
    • COI: 1:CAS:528:DC%2BD3MXhs12gt7w%3D
    • Heikkinen T, Ekblad U, Laine K. Transplacental transfer of amitriptyline and nortriptyline in isolated perfused human placenta. Psychopharmacology (Berl). 2001;153:450–4.
    • (2001) Psychopharmacology (Berl) , vol.153 , pp. 450-454
    • Heikkinen, T.1    Ekblad, U.2    Laine, K.3
  • 63
    • 0015306264 scopus 로고
    • Plasma disappearance of nortriptyline in a newborn infant following placental transfer from an intoxicated mother: evidence for drug metabolism
    • COI: 1:STN:280:DyaE387lsl2ruw%3D%3D, PID: 5017806
    • Sjoqvist F, Bergfors PG, Borga O, Lind M, Ygge H. Plasma disappearance of nortriptyline in a newborn infant following placental transfer from an intoxicated mother: evidence for drug metabolism. J Pediatr. 1972;80:496–500.
    • (1972) J Pediatr , vol.80 , pp. 496-500
    • Sjoqvist, F.1    Bergfors, P.G.2    Borga, O.3    Lind, M.4    Ygge, H.5
  • 66
  • 67
    • 33947728974 scopus 로고    scopus 로고
    • The clinical pharmacokinetics of escitalopram
    • COI: 1:CAS:528:DC%2BD2sXlt1Grsrs%3D, PID: 17375980
    • Rao N. The clinical pharmacokinetics of escitalopram. Clin Pharmacokinet. 2007;46:281–90.
    • (2007) Clin Pharmacokinet , vol.46 , pp. 281-290
    • Rao, N.1
  • 68
    • 79953329390 scopus 로고    scopus 로고
    • Duloxetine: clinical pharmacokinetics and drug interactions
    • COI: 1:CAS:528:DC%2BC3MXntlKlsbg%3D, PID: 21366359
    • Knadler MP, Lobo E, Chappell J, Bergstrom R. Duloxetine: clinical pharmacokinetics and drug interactions. Clin Pharmacokinet. 2011;50:281–94.
    • (2011) Clin Pharmacokinet , vol.50 , pp. 281-294
    • Knadler, M.P.1    Lobo, E.2    Chappell, J.3    Bergstrom, R.4
  • 69
    • 0020405126 scopus 로고
    • Antidepressant properties of trazodone
    • COI: 1:CAS:528:DyaL38XmtVOnsbs%3D, PID: 6764164
    • Bryant SG, Ereshefsky L. Antidepressant properties of trazodone. Clin Pharm. 1982;1:406–17.
    • (1982) Clin Pharm , vol.1 , pp. 406-417
    • Bryant, S.G.1    Ereshefsky, L.2
  • 70
    • 0015486188 scopus 로고
    • The metabolism and placental transfer of isocarboxazid in pregnant rats
    • COI: 1:CAS:528:DyaE3sXlt1yjug%3D%3D
    • Satoh T, Yamamoto S, Moroi K. The metabolism and placental transfer of isocarboxazid in pregnant rats. Jpn J Pharmacol. 1972;22(5):629–33.
    • (1972) Jpn J Pharmacol , vol.22 , Issue.5 , pp. 629-633
    • Satoh, T.1    Yamamoto, S.2    Moroi, K.3


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