Combination of amikacin and doxycycline against multidrug-resistant and extensively drug-resistant tuberculosis

International Journal of Antimicrobial Agents

Volumn 45, Issue 4, 2015, Pages 406-412

  Gonzalo, Ximena ^a,b,c   Casali, Nicola ^b,c   Broda, Agnieszka ^b,c   Pardieu, Claire ^b   Drobniewski, Francis ^a,b,c  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Amikacin; Doxycycline; Drug synergism; Microbial sensitivity tests; Multidrug resistant; Tuberculosis

Indexed keywords

AMIKACIN; CAPREOMYCIN; DOXYCYCLINE; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; LINEZOLID; OFLOXACIN; PROTIONAMIDE; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIUM ISOLATE; COMBINATION CHEMOTHERAPY; CONCENTRATION (PARAMETERS); DRUG ACTIVITY; DRUG POTENTIATION; DRUG RESEARCH; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; FRACTIOINAL INHIBITORY CONCENTRATION INDICES; GENE SEQUENCE; MICROBIOLOGICAL EXAMINATION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; UNITED KINGDOM; WHOLE GENOME SEQUENCING; DRUG EFFECTS; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; PILOT STUDY;

AMIKACIN; ANTITUBERCULAR AGENTS; DOXYCYCLINE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG SYNERGISM; HUMANS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PILOT PROJECTS; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 84925514339     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2014.11.017     Document Type: Article

References (38)

1. A. Zumla, I. Abubakar, M. Raviglione, M. Hoelscher, L. Ditiu, and T.D. McHugh Drug-resistant tuberculosis - current dilemmas, unanswered questions, challenges, and priority needs J Infect Dis 205 Suppl. 2 2012 S228 S240
2. M.T. Gler, V. Skripconoka, E. Sanchez-Garavito, H. Xiao, J.L. Cabrera-Rivero, and D.E. Vargas-Vasquez Delamanid for multidrug-resistant pulmonary tuberculosis N Engl J Med 366 2012 2151 2160
3. J.C. Palomino, and A. Martin TMC207 becomes bedaquiline, a new anti-TB drug Future Microbiol 8 2013 1071 1080
4. L. Amaral, J.E. Kristiansen, M. Viveiros, and J. Atouguia Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy J Antimicrob Chemother 47 2001 505 511
5. Y. Bhusal, C.M. Shiohira, and N. Yamane Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis Int J Antimicrob Agents 26 2005 292 297
6. P. Forgacs, N.L. Wengenack, L. Hall, S.K. Zimmerman, M.L. Silverman, and G.D. Roberts Tuberculosis and trimethoprim-sulfamethoxazole Antimicrob Agents Chemother 53 2009 4789 4793
7. M. Salvatore, and B. Meyer Tetracyclines and chloramphenicol 7th ed. Mandell, Douglas, and Bennett's principles and practice of infectious diseases vol. 1 2010 Churchill Livingston Elsevier Philadelphia, PA 385 401
8. Y. Balabanova, M. Ruddy, J. Hubb, M. Yates, N. Malomanova, and I. Fedorin Multidrug-resistant tuberculosis in Russia: clinical characteristics, analysis of second-line drug resistance and development of standardized therapy Eur J Clin Microbiol Infect Dis 24 2005 136 139
9. X.Z. Li, L. Zhang, and H. Nikaido Efflux pump-mediated intrinsic drug resistance in Mycobacterium smegmatis Antimicrob Agents Chemother 48 2004 2415 2423
10. S. Ramón-García, C. Martín, E. De Rossi, and J.A. Aínsa Contribution of the Rv2333c efflux pump (the Stp protein) from Mycobacterium tuberculosis to intrinsic antibiotic resistance in Mycobacterium bovis BCG J Antimicrob Chemother 59 2007 544 547
11. D.N. Wilson Ribosome-targeting antibiotics and mechanisms of bacterial resistance Nat Rev Microbiol 12 2014 35 48
12. D. Vicente, and E. Pérez-Trallero Tetracyclines, sulfonamides, and metronidazole [in Spanish] Enferm Infecc Microbiol Clin 28 2010 122 130
13. M.H. Gschwend, W. Martin, A. Erenmemisoglu, M. Scherm, C. Dilger, and U. Tamur Pharmacokinetics and bioequivalence study of doxycycline capsules in healthy male subjects Arzneimittelforschung 57 2007 347 351
14. C.G. MacArthur, A.J. Johnson, M.V. Chadwick, and H.J. Wingfield The absorption and sputum penetration of doxycycline J Antimicrob Chemother 4 1978 509 514
15. M.F. Reeves, P.A. Lohr, J.L. Hayes, B.J. Harwood, and M.D. Creinin Doxycycline serum levels at the time of dilation and evacuation with two dosing regimens Contraception 79 2009 129 133
16. H. Thadepalli, A.K. Mandal, V.T. Bach, and S.S. Oparah Tissue levels of doxycycline in the human lung and pleura Chest 78 1980 304 305
17. D. Falzon, E. Jaramillo, H.J. Schünemann, M. Arentz, M. Bauer, and J. Bayona WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update Eur Respir J 38 2011 516 528
18. World Health Organization Guidelines for surveillance of drug resistance in tuberculosis 2009 WHO Geneva, Switzerland
19. A. Krüüner, M.D. Yates, and F.A. Drobniewski Evaluation of MGIT 960-based antimicrobial testing and determination of critical concentrations of first- and second-line antimicrobial drugs with drug-resistant clinical strains of Mycobacterium tuberculosis J Clin Microbiol 44 2006 811 818
20. B. Springer, K. Lucke, R. Calligaris-Maibach, C. Ritter, and E.C. Bottger Quantitative drug susceptibility testing of Mycobacterium tuberculosis by use of MGIT 960 and EpiCenter instrumentation J Clin Microbiol 47 2009 1773 1780
21. T.C. Chou, and P. Talalay Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors Adv Enzyme Regul 22 1984 27 55
22. F.C. Odds Synergy, antagonism, and what the chequerboard puts between them J Antimicrob Chemother 52 2003 1
23. N. Casali, V. Nikolayevskyy, Y. Balabanova, S.R. Harris, O. Ignatyeva, and I. Kontsevaya Evolution and transmission of drug-resistant tuberculosis in a Russian population Nat Genet 46 2014 279 286
24. M. Finken, P. Kirschner, A. Meier, A. Wrede, and E.C. Bottger Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: alterations of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA pseudoknot Mol Microbiol 9 1993 1239 1246
25. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing; twenty-third informational supplement. Document M100-S23 2013 CLSI Wayne, PA
26. T. Kamala, D. Herbert, P. Venkatesan, and C.N. Paramasivan Minimal inhibitory concentrations of lomefloxacin and minocycline against drug-sensitive and drug-resistant isolates of M. tuberculosis compared on L-J and 7H11 media Int J Lepr Other Mycobact Dis 65 1997 375 378
27. T.S. Ginzburg, and R.O. Drabkina The antitubercular activity of oxytetracycline [in Ukrainian] Mikrobiol Zh 31 1969 410 412
28. G.L. Hobby, and T.F. Lenert Antituberculous activity of tetracycline and related compounds Am Rev Tuberc 72 1955 367 372
29. N.F. Walker, S.O. Clark, T. Oni, N. Andreu, L. Tezera, and S. Singh Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases Am J Respir Crit Care Med 185 2012 989 997
30. R.M. Cayre, and J. Viallier Bacteriostatic action of tetracycline, alone or combined with antituberculosis antibiotics, on Mycobacterium tuberculosis [in French] C R Seances Soc Biol Fil 150 1956 1202 1204
31. B.S. Choudhuri, S. Bhakta, R. Barik, J. Basu, M. Kundu, and P. Chakrabarti Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis Biochem J 367 2002 279 285
32. P.E.A. Silva, F. Bigi, M.P. Santangelo, M.I. Romano, C. Martín, and A. Cataldi Characterization of P55, a multidrug efflux pump in Mycobacterium bovis and Mycobacterium tuberculosis Antimicrob Agents Chemother 45 2001 800 804
33. J.A. Aínsa, M.C.J. Blokpoel, I. Otal, D.B. Young, K.A. De Smet, and C. Martín Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis J Bacteriol 180 1998 5836 5843
34. E. De Rossi, J.A. Aínsa, and G. Riccardi Role of mycobacterial efflux transporters in drug resistance: an unresolved question FEMS Microbiol Rev 30 2006 36 52
35. A.K. Gupta, V.M. Katoch, D.S. Chauhan, R. Sharma, M. Singh, and K. Venkatesan Microarray analysis of efflux pump genes in multidrug-resistant Mycobacterium tuberculosis during stress induced by common anti-tuberculous drugs Microb Drug Resist 16 2010 21 28
36. M.K. Calgin, F. Sahin, B. Turegun, D. Gerceker, M. Atasever, and D. Koksal Expression analysis of efflux pump genes among drug-susceptible and multidrug-resistant Mycobacterium tuberculosis clinical isolates and reference strains Diagn Microbiol Infect Dis 76 2013 291 297
37. P. Hao, Z. Shi-Liang, L. Ju, D. Ya-Xin, H. Biao, and W. Xu The role of ABC efflux pump, Rv1456c-Rv1457c-Rv1458c, from Mycobacterium tuberculosis clinical isolates in China Folia Microbiol (Praha) 56 2011 549 553
38. Pyrazinamide Tuberculosis (Edinb) 88 2008 141 144