Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte

Molecular and Cellular Biochemistry

Volumn 401, Issue 1-2, 2015, Pages 39-47

  Hashimoto, Yoko ^a   Matsuzaki, Etsuko ^a,b   Higashi, Katsumasa ^a   Takahashi Yanaga, Fumi ^c   Takano, Aiko ^a   Hirata, Masato ^a   Nishimura, Fusanori ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA DENTAL COLLEGE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Adipogenic differentiation; C EBP ; C3H10T1 2; cAMP; Mesenchymal stem cell; Sphingosine 1 phosphate

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP; FATTY ACID BINDING PROTEIN 4; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SPHINGOSINE 1 PHOSPHATE; CEBPB PROTEIN, MOUSE; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; INTRACELLULAR SIGNALING; MESENCHYMAL STEM CELL; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; OSTEOCYTE; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; ANIMAL; BONE DEVELOPMENT; CELL LINE; CULTURE TECHNIQUE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADIPOCYTES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CYCLIC AMP; GENE EXPRESSION REGULATION; LYSOPHOSPHOLIPIDS; MESENCHYMAL STROMAL CELLS; MICE; OSTEOGENESIS; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 84925494625     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2290-1     Document Type: Article

References (38)

1. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284:143–147
2. Baksh D, Song L, Tuan RS (2004) Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med 8:301–316
3. Hao W, Dong J, Jiang M, Wu J, Cui F, Zhou D (2010) Enhanced bone formation in large segmental radial defects by combining adipose-derived stem cells expressing bone morphogenetic protein 2 with nHA/RHLC/PLA scaffold. Int Orthop 34:1341–1349
4. Cawthorn WP, Bree AJ, Yao Y, Du B, Hemati N, Martinez-Santibañez G, MacDougald OA (2012) Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. Bone 50:477–489
5. Rahman S, Czernik PJ, Lu Y, Lecka-Czernik B (2012) β-catenin directly sequesters adipocytic and insulin sensitizing activities but not osteoblastic activity of PPARγ2 in marrow mesenchymal stem cells. PLoS ONE 7:e51746
6. Reusch JE, Colton LA, Klemm DJ (2012) CREB activation induces adipogenesis in 3T3-L1 cells. Mol Cell Biol 20:1008–1020
7. Jia B, Madsen L, Petersen RK, Techer N, Kopperud R, Ma T, Doskeland SO, Alhaud G, Wang J, Amri EZ, Kristiansen K (2012) Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells. PLoS ONE 7:e34114. doi:10.1371/journal.pone.0034114
8. Cao Z, Umek RM, McKnight SL (1991) Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 5:1538–1552
9. Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM (1994) mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8:1224–1234
10. Smas CM, Sul HS (1995) Control of adipocyte differentiation. Biochem J 309:697–710
11. Komori T, Yagi H, Nomura S et al (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755–764
12. Otto F, Thornell AP, Crompton T et al (1997) Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89:765–771
13. Rawadi G, Vayssière B, Dunn F et al (2003) BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J Bone Miner Res 18:1842–1853
14. Matsuzaki E, Takahashi-Yanaga F, Miwa Y, Hirata M et al (2006) Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines. J Bone Miner Res 21:1307–1316
15. Spiegel S, Milstien S (2002) Sphingosine 1-phosphate, a key cell signaling molecule. J Biol Chem 277:25851–25854
16. Anliker B, Chun J (2004) Lysophospholipid G protein-coupled receptors. J Biol Chem 279:20555–20558
17. Spiegel S, Milstien S (2003) Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 4:397–407
18. Zhao Z, Chen Z, Zhao X, Pan F et al (2011) Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions. J Biomed Sci 18:37. doi:10.1186/1423-0127-18-37
19. Nincheri P, Luciani P, Squecco R, Donati C et al (2009) Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells. Cell Mol Life Sci 66:1741–1754
20. Matsuzaki E, Hiratsuka S, Hamachi T, Takahashi-Yanaga F et al (2013) Sphingosine-1-phosphate promotes the nuclear translocation of β-catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell like cell lines. Bone 55:315–324
21. Sato C, Iwasaki T, Kitano S, Tsunemi S, Sano H (2012) Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation. Biochem Biophys Res Commun 423:200–205
22. Moon MH, Jeong JK, Lee JH, Park YG, Lee YJ, Seol JW, Park SY (2012) Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model. Exp Mol Med 44:603–614
23. Hashimoto T, Igarashi J, Kosaka H (2009) SPHK is induced in 3T3-L1 cells and promotes adipogenesis. J Lipid Res 50:602–610
24. Pitson SM, Pebay A (2009) Regulation of stem cell pluripotency and neural differentiation by lysophospholipids. Neurosignals 17:242–254
25. Tang QQ, Otto TC, Lane MD (2004) Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc Natl Acad Sci USA 101:9607–9611
26. Khayat G, Resenweig DH, Quinn TM (2012) Low frequency mechanical stimulation inhibits adipogenic differentiation of C3H10T1/2 mesenchymal stem cells. Differentiation 83:179–184
27. Huang K, Fu J, Li W, Dong S, Yu S, Hu Z, Wang H, Xie Z (2014) MicroRNA-125 regulates osteogenic differentiation of mesenchymal stem cells by targeting Cbfβ in vitro. Biochimie 102:47–55
28. Laudes M, Christodoulides C, Sewter C, Rochford JJ, Considine RV, Sethi JK, Vidal-Pulg A, O’rahilly S (2004) Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis. J Biol Chem 279:11711–11718
29. Van Brocklyn JR, Lee MJ, Menzeleev R, Olivera A et al (1998) Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. J Cell Biol 142:229–240
30. Means CK, Miyamoto S, Chun J, Brown JH (2008) S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses. J Biol Chem 283:11954–11963
31. Wang J, Badeanlou L, Bielawski J, Ciaraldi TP, Samad F (2014) Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance. Am J Physiol Endocrinol Metab 306:E756–E768
32. Petrie Aronin CE, Shin SJ, Naden KB, Rios PD Jr et al (2010) The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720. Biomaterials 31:6417–6424
33. Petrie Aronin CE, Sefcik LS, Tholpady SS, Tholpady A et al (2010) FTY720 promotes local microvascular network formation and regeneration of cranial bone defects. Tissue Eng Part A 16:1801–1809
34. Sakaue H, Ogawa W, Matsumoto M, Kuroda S, Takata M, Sugimoto T, Spiegelman BM, Kasuga M (1998) Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase. J Biol Chem 1273:28945–28952
35. Zhang H, Desai NN, Olivera A, Seki T, Brooker G, Spiegel S (1991) Sphingosine-1-phosphate, a novel lipid, involved cellular proliferation. J Cell Biol 114:155–167
36. Carpio LC, Stephan E, Kamer A, Dziak R (1999) Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells. Prostaglandins Leukot Essent Fatty Acids 61:267–273
37. Pandey V, Vijayakumar MV, Kaul-Ghanekar R, Mamgain H, Paknikar K, Bhat MK (2009) Atomic force microscopy, biochemical analysis of 3T3-L1 cells differentiated in the absence and presence of insulin. Biochim Biophys Acta 1790:57–64
38. Roztocil E, Nicholl SM, Davies MG (2009) Mechanisms of sphingosine-1-phosphate-induced akt-dependent smooth muscle cell migration. Surgery 145:34–41