Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 61, Issue 5, 1999, Pages 267-273

  Carpio, L C ^a   Stephan, E ^b   Kamer, A ^b   Dziak, R ^b  

^a HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM CHANNEL BLOCKING AGENT; CERAMIDE; CERAMIDE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SPHINGOLIPID; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; VERAPAMIL;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVATION; FETUS; HUMAN; HUMAN CELL; MITOGENESIS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SPECIES DIFFERENCE;

ANIMALIA;

EID: 0033396710     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.1999.0100     Document Type: Article

References (34)

1. Haimovitz-Friedman A., Kolesnick R. N., Fuks Z. Ceramide signaling in apoptosis. British Med Bull. 53:1997;539-553.
2. Wiesner D., Dawson G. Programmed cell death in neuromotor cells involves the generation of ceramide. Glycoconjugate J. 13:1996;327-333.
3. Gomez-Muños A., Duffy P. A., Martin A. Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: antagonism by cell-permeable ceramides. Molecular Pharmacology. 47:1995;833-839.
4. Hannun Y. A., Merrill A. H., Bell R. M. Use of sphingomyelin as an inhibitor of protein kinase C. Methods in Enzymol. 201:1991;316-328.
5. Zhang H, Buckley N. E., Gibson K., Spiegel S. Sphingosine stimulates cellular proliferation via a protein kinase C-independent pathway. J Biol Chem. 265:1990;76-81.
6. Zhang H, Desai N. N., Olivera A., Seki T., Brooker G., Spiegel S. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J Cell Biol. 114:1991;155-167.
7. Spiegel S., Merrill A. H. J. Sphingolipid metabolism and cell growth regulation. FASEB J. 10:1996;1388-1397.
8. Candela M., Barker S. C., Ballou L. R. Sphingosine synergistically stimulates tumor necrosis factor a-induced prostaglandin E2 production in human fobroblasts. J Exp Med. 174:1991;1363-1369.
9. Hannun Y. A. The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem. 269:1994;3125-3128.
10. Olivera A., Spiegel S. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature. 365:1993;557-560.
11. Zhang W., Dziak R. M., Aletta J. M. EGF-mediated phosphorylation of extracellular signal-regulated kinases in osteoblastic cells. J Cell Physiol. 162:1995;348-358.
12. Davis R. J. The mitogen-activated protein kinase signal transduction pathway. J Biol Chem. 268:1993;14553-14556.
13. Hunter T. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling. Cell. 80:1995;225-236.
14. Guo C., Zheng C., Martin-Padura E., Bian Z. C., Guan J. L. Differential stimulation of proline-rich tyrosine kinase 2 and mitogen activated protein kinase by sphingosine-1-phosphate. Eur J Biochem. 257:1998;403-408.
15. Liu R., Farach-Carson M. C., Karin N. J. Effects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellular stores. Biochem Biophys Res Comm. 214:1995;676-684.
16. Carpio L. C., Dziak R. Sphingolipids effects on cytosolic calcium and proliferation in osteoblastic cells. J Bone Min Res. 12:1997;T349.
17. Shiau H., Carpio L. C., Dziak R. Effects of ceramide on cytosolic calcium in rat osteoblastic cells. J Dent Res. 77:1998;1138.
18. Carpio L. C., Shiau H., Dziak R. Ceramide effects on normal rat osteoblastic cell proliferation and differentiation. J Dent Res. 77:1998;1139.
19. Kozawa O., Haruhito T., Matsuno H., Uematsu T. Activation of mitogen-activated protein kinase is involved in sphingosine 1-phosphate-stimulated interleukin-6 synthesis in osteoblasts. FEBS Letters. 418:1997;149-151.
20. Luben R., Wong G., Cohn D. Biochemical characterization with parathohormone and calcitonin of isolated bone cells: provisional identification of osteoclasts and osteoblasts. Endocrinology. 99:1976;526-534.
21. Shlossman M., Brown M., Shapiro E., Dziak R. Calcitonin effects on isolated bone cells. Calcified Tissue International. 39:1982;190-196.
22. Strum J. C., Ghosh S., Bell R. M. Lipid second messengers. A role in cell growth regulation and cell cycle progression. Adv Exp Med & Biol. 407:1997;421-431.
23. Desai N. N., Carlson R. O., Mattie M. E. Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts. J Cell Biol. 121:1993;1385-1395.
24. Yule D. I., Wu D., Essington T. E., Shayman J., Williams J. A. Sphingosine metabolism induces Ca2+ oscillations in rat pacreatic acinar cells. J Biol Chem. 268:1993;12353-12358.
25. Kindman L. A., Kim S., McDonald T., Gardner P. Characterization of a novel intracellular sphingolipid-gated Ca+2-permeable channel from rat basophilic leukemia cells. J Biol Chem. 269:1994;13088-13091.
26. Bielawska A., Linardic C. M., Hannun Y. A. Modulation of cell growth and differentiation by ceramide. FEBS Letters. 307:1992;211-214.
27. Okazaki T., Bielawska A., Bell R. M., Hannun Y. A. Role of ceramide as a lipid mediator of α25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem. 265:1990;15823-15831.
28. Spiegel S. Sphingosine and sphingosine-1-phosphate in cellular proliferation:relationship with protein kinase C and phosphatidic acid. J Lipid Mediators. 8:1993;169-175.
29. Kitahima I., Soejima Y., Takasaki I., Beppu H., Tokioka T. Maruyama, Ceramide-induced nuclear factor translocation of NF-kB is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts. Bone. 19:1996;263-270.
30. Jayadev S., Liu B., Bielawska A. E. Role of ceramide in cell cycle arrest. J Biol Chem. 270:1995;2047-2052.
31. Jarvis W. D., Kolesnick R. N., Fornari F. A., Traylor R. S., Gewitz D. A., Grant S. Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc Natl Acad Sci USA. 91:1994;73-77.
32. Marshall C. J. MAP kinase kinase kinase, Map kinase kinase, and MAP kinase. Curr Op Genet Dev. 4:1994;82-89.
33. Chaudhary L. R., Avioli L. V. Activation of extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2) by FGF-2 and PDGF-BB in normal human osteoblastic and bone marrow stromal cells: differences in mobility and in-gel renaturation of ERK 1 in human, rat, and mouse osteoblastic cells. Biochem Biophys Res Commun. 238:1997;134-139.
34. Chaudhary L. R., Avioli L. Identification and activation of mitogen activated protein (MAP) kinase in normal human osteoblastic and bone marrow stromal cells: attenuation of MAP kinase activation by cAMP, parathyroid hormone and forskolin. Mol Cell Biochem. 178:1998;59-68.