Human cyclic nucleotide phosphodiesterases possess a much broader substrate-specificity than previously appreciated

FEBS Letters

Volumn 585, Issue 20, 2011, Pages 3259-3262

  Reinecke, Daniel ^a   Burhenne, Heike ^a   Sandner, Peter ^b   Kaever, Volkhard ^a   Seifert, Roland ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

Cyclic nucleotide; HPLC MS; Phosphodiesterase

Indexed keywords

CYCLIC AMP; CYCLIC CMP; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 2; CYCLIC UMP;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME DEGRADATION; ENZYME SPECIFICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; MASS SPECTROMETRY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; THROMBOCYTE AGGREGATION;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; CYTOSINE NUCLEOTIDES; HUMANS; HYDROLYSIS; SUBSTRATE SPECIFICITY;

EID: 80054064690     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.09.004     Document Type: Article

References (25)

1. M. Desch, E. Schinner, F. Kees, F. Hofmann, R. Seifert, and J. Schlossmann Cyclic cytidine 3′,5′-monophosphate (cCMP) signals via cGMP kinase I FEBS Lett. 584 2010 3979 3984
2. M. Conti, and J.A. Beavo Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling Annu. Rev. Biochem. 76 2007 481 511
3. J.A. Beavo, and A.T. Bender Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use Pharmacol. Rev. 58 2006 488 520 (Pubitemid 44394910)
4. T.R. Anderson Cyclic cytidine 3′,5′-monophosphate (cCMP) in cell regulation Mol. Cell. Endocrinol. 28 1982 373 385 (Pubitemid 13253568)
5. S.Y. Cech, and L.J. Ignarro Cytidine 3′,5′-monophosphate (cyclic CMP) formation in mammalian tissues Science 198 1977 1063 1065 (Pubitemid 8239007)
6. R.M. Gaion, and G. Krishna Cytidylate cyclase: the product isolated by the method of Cech and Ignarro is not cytidine 3′,5′-monophosphate Biochem. Biophys. Res. Commun. 86 1979 105 111
7. R.P. Newton, S.G. Salih, B.J. Salvage, and E.E. Kingston Extraction, purification and identification of cytidine 3′,5′-cyclic monophosphate from rat tissues Biochem. J. 221 1984 665 673 (Pubitemid 14061648)
8. R.P. Newton, E.E. Kingston, N.A. Hakeem, S.G. Salih, J.H. Beynon, and C.D. Moyse Extraction, purification, identification and metabolism of 3′,5′-cyclic UMP, 3′,5′-cyclic IMP and 3′,5′-cyclic dTMP from rat tissues Biochem. J. 236 1986 431 439 (Pubitemid 16036989)
9. 4, 2′-O-dibutyryl cytidine 3′:5′-cyclic monophosphate of neutrophil activation Biochem. Biophys. Res. Commun. 174 1991 258 267
10. D.M. Helfman, N. Katoh, and J.F. Kuo Purification and properties of cyclic CMP phosphodiesterase Adv. Cyclic Nucleotide Protein Phosphoryla. Res. 16 1984 403 416
11. R.P. Newton, M.A. Bayliss, J.A. Khan, A. Bastani, A.C. Wilkins, D.E. Games, T.J. Walton, A.G. Brenton, and F.M. Harris Kinetic analysis of cyclic CMP-specific and multifunctional phosphodiesterases by quantitative positive-ion fast atom bombardment mass spectrometry Rapid Commun. Mass Spectrom. 13 1999 574 584 (Pubitemid 29160408)
12. U. Klotz, and K. Stock Evidence for a cyclic nucleotide-phosphodiesterase with high specificity for cyclic uridine-3′,5′-monophosphate in rat adipose tissue Naunyn-Schmiedebergs Arch. Pharmak. 269 1971 117 120
13. J.G. Hardman, and E.W. Sutherland A cyclic 3′, 5′-nucleotide phosphodiesterase from heart with specificity for uridine 3′,5′- phosphate J. Biol. Chem. 240 1965 3704 3705
14. R. Lorenzetti, S. Lilla, J.L. Donato, and G. de Nucci Simultaneous quantification of GMP, AMP, cyclic GMP and cyclic AMP by liquid chromatography coupled tandem mass spectrometry J. Chromatograph. B 859 2007 37 41 (Pubitemid 47626088)
15. S.H. Soderling, S.J. Bayuga, and J.A. Beavo Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase Proc. Natl. Acad. Sci. USA 95 1998 8991 8996 (Pubitemid 28350602)
16. 2+-induced hydrophobic site on calmodulin: application for purification of calmodulin by phenyl-sepharose affinity chromatography Biochem. Biophys. Res. Commun. 29 1982 830 836
17. D.A. Fisher, J.F. Smith, J.S. Pillar, S.H. St Denis, and J.B. Cheng Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase J. Biol. Chem. 273 1998 15559 15564 (Pubitemid 28298168)
18. S.H. Soderling, S.J. Bayuga, and J.A. Beavo Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases J. Biol. Chem. 273 1998 15553 15558 (Pubitemid 28298167)
19. M. Göttle, S. Dove, F. Kees, J. Schlossmann, J. Geduhn, B. König, Y. Shen, W.J. Tang, V. Kaever, and R. Seifert Cytidylyl and uridylyl cyclase activity of Bacillus anthracis edema factor and Bordetella pertussis CyaA Biochemistry 49 2010 5494 5503
20. D.E. Voth, E.E. Hamm, L.G. Nguyen, A.E. Tucker, I.I. Salles, W. Ortiz-Leduc, and J.D. Ballard Bacillus anthracis oedema factor toxin as cause of tissue necrosis and cell type-specific cytotoxicity Cell. Microbiol. 7 2005 1139 1149 (Pubitemid 41030939)
21. D.H. Maurice, D. Palmer, D.G. Tilley, H.A. Dunkerley, S.J. Netherton, D.R. Raymond, H.S. Elbatarny, and S.L. Jimmo Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system Mol. Pharmacol. 64 2003 533 546 (Pubitemid 37048555)
22. Y. Shakur, L.S. Holst, T.R. Landstrom, M. Movsesian, E. Degerman, and V. Manganiello Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family Prog. Nucleic Acid Res. Mol. Biol. 66 2001 241 277
23. F. Hofmann, D. Bernhard, R. Lukowski, and P. Weinmeister CGMP regulated protein kinases (cGK) Handb. Exp. Pharmacol. 191 2009 137 162
24. C.W. Dessauer Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling Mol. Pharmacol. 76 2009 935 941
25. F.A. Antoni Molecular diversity of cyclic AMP signalling Front. Neuroendocrin. 21 2000 103 132 (Pubitemid 30228501)