Emodin protects against concanavalin a-induced hepatitis in mice through inhibiting activation of the p38 MAPK-NF-κB signaling pathway

Cellular Physiology and Biochemistry

Volumn 35, Issue 4, 2015, Pages 1557-1570

  Xue, Jihua ^a   Chen, Feng ^a   Wang, Jing ^a   Wu, Shanshan ^a   Zheng, Min ^a   Zhu, Haihong ^a   Liu, Yanning ^a   He, Jiliang ^b   Chen, Zhi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Chemokines; Con A; Cytokines; Emodin; Immune cells; NF B; p38 MAPK

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTEGRIN; ASPARTATE AMINOTRANSFERASE; CHEMOKINE RECEPTOR CXCR2; CONCANAVALIN A; CXCL3 CHEMOKINE; EMODIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTEGRIN ALPHA M; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CD11B ANTIGEN; CHEMOKINE; CYTOKINE; PROTECTIVE AGENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOIMMUNE HEPATITIS; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LYMPHOCYTE COUNT; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; BLOOD; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; HEPATITIS; IMMUNOLOGY; LIVER; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANIMALIA; MUS;

ALANINE TRANSAMINASE; ANIMALS; ANTIGENS, CD11B; ASPARTATE AMINOTRANSFERASES; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CHEMOKINES; CONCANAVALIN A; CYTOKINES; EMODIN; HEPATITIS; LIVER; MALE; MICE; MICE, INBRED BALB C; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTECTIVE AGENTS; SIGNAL TRANSDUCTION;

EID: 84925437293     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000373971     Document Type: Article

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