Methyl-donor deficiency in adolescence affects memory and epigenetic status in the mouse hippocampus

Genes, Brain and Behavior

Volumn 14, Issue 3, 2015, Pages 301-309

  Tomizawa, H ^a   Matsuzawa, D ^a,b   Ishii, D ^a   Matsuda, S ^a,c   Kawai, K ^a   Mashimo, Y ^d   Sutoh, C ^a,b   Shimizu, E ^a,b  

^a Department of Cognitive Behavioral Physiology ^*  (Japan)

^b CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^d CHIBA UNIVERSITY   (Japan)

Author keywords

Adolescence; AMPA receptor; Choline; Contextual fear conditioning; DNA methylation; Epigenetics; Fear extinction; Folate; Methionine; Novel object recognition

Indexed keywords

CHOLINE; FOLIC ACID; GRIA1 PROTEIN; HOMOCYSTEINE; MEMBRANE PROTEIN; METHIONINE; UNCLASSIFIED DRUG; AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EPIGENETICS; FEAR; FOLIC ACID DEFICIENCY; GENE EXPRESSION; HIPPOCAMPUS; HYPOTHESIS; LEARNING; MALE; MEMORY; METHYL DONOR DEFICIENCY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REINFORCEMENT; VITAMIN DEFICIENCY; AGE; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DEFICIENCY; DIET; DNA METHYLATION; GENETIC EPIGENESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NUTRITIONAL REQUIREMENT; PHYSIOLOGY; PSYCHOLOGY;

MUS;

AGE FACTORS; ANIMALS; CHOLINE; CHOLINE DEFICIENCY; DIET; DNA METHYLATION; EPIGENESIS, GENETIC; FOLIC ACID; FOLIC ACID DEFICIENCY; HIPPOCAMPUS; HOMOCYSTEINE; MEMORY; METHIONINE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; NUTRITIONAL REQUIREMENTS; PROMOTER REGIONS, GENETIC; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE;

EID: 84925394791     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/gbb.12207     Document Type: Article

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