Doxycycline exerts multiple anti-allergy effects to attenuate murine allergic conjunctivitis and systemic anaphylaxis

Biochemical Pharmacology

Volumn 91, Issue 3, 2014, Pages 359-368

  Su, Wenru ^a,b   Wan, Qian ^a   Han, Longhui ^a   Huang, Jingwen ^a   Chen, Xiaoqing ^a,c   Chen, Guihua ^b   Zheng, Song Guo ^b,c   Liang, Dan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Allergy; B cells; Doxycycline; Histamine; Mast cells

Indexed keywords

DOXYCYCLINE; IMMUNOGLOBULIN E; INTERLEUKIN 4; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR NECROSIS FACTOR ALPHA; ANTIALLERGIC AGENT; ANTIHISTAMINIC AGENT; CADHERIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LEUKOCYTE ANTIGEN; NOS3 PROTEIN, MOUSE; PROTEIN KINASE B; VASCULAR ENDOTHELIAL CADHERIN;

ALLERGIC CONJUNCTIVITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; EXPERIMENTAL ALLERGIC CONJUNCTIVITIS; HISTAMINE INDUCED SYSTEMIC ANAPHYLAXIS; HISTAMINE RELEASE; IN VITRO STUDY; INFLAMMATORY CELL; MAST CELL; MOUSE; NONHUMAN; PASSIVE SYSTEMIC ANAPHYLAXIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYSTEMIC ANAPHYLAXIS; TREATMENT OUTCOME; ANAPHYLAXIS; ANIMAL; BAGG ALBINO MOUSE; CONJUNCTIVITIS, ALLERGIC; DRUG EFFECTS; IMMUNOLOGY; METABOLISM;

ANAPHYLAXIS; ANIMALS; ANTI-ALLERGIC AGENTS; ANTIGENS, CD; CADHERINS; CONJUNCTIVITIS, ALLERGIC; DOXYCYCLINE; HISTAMINE ANTAGONISTS; IMMUNOGLOBULIN E; MAST CELLS; MICE; MICE, INBRED BALB C; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84925391754     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.08.001     Document Type: Article

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