Increased PTPN22 expression and defective CREB activation impair regulatory t-cell differentiation in non-st-segment elevation acute coronary syndromes

Journal of the American College of Cardiology

Volumn 65, Issue 12, 2015, Pages 1175-1186

  Flego, Davide ^a   Severino, Anna ^a   Trotta, Francesco ^a   Previtero, Marco ^a   Ucci, Sarassunta ^a   Zara, Chiara ^a   Massaro, Gianluca ^a   Pedicino, Daniela ^a   Biasucci, Luigi M ^a   Liuzzo, Giovanna ^a   Crea, Filippo ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

dysregulation; immune system; signaling pathway

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERLEUKIN 2; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; T LYMPHOCYTE RECEPTOR; TYROSINE; CREBBP PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; PTPN22 PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; EX VIVO STUDY; FLOW MEASUREMENT; FOLLOW UP; HELPER CELL; HUMAN; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; MOLECULAR MECHANICS; NON ST SEGMENT ELEVATION ACUTE CORONARY SYNDROME; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; STABLE ANGINA PECTORIS; T LYMPHOCYTE ACTIVATION; ACUTE CORONARY SYNDROME; ADAPTIVE IMMUNITY; AGED; ANALYSIS OF VARIANCE; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; CASE CONTROL STUDY; COMPARATIVE STUDY; ELECTROCARDIOGRAPHY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEART INFARCTION; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PROGNOSIS; RADIOGRAPHY; REFERENCE VALUE; RISK ASSESSMENT; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ACUTE CORONARY SYNDROME; ADAPTIVE IMMUNITY; AGED; ANALYSIS OF VARIANCE; ANGINA PECTORIS; CASE-CONTROL STUDIES; CORONARY ANGIOGRAPHY; CREB-BINDING PROTEIN; ELECTROCARDIOGRAPHY; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PROGNOSIS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; REFERENCE VALUES; RISK ASSESSMENT; SIGNAL TRANSDUCTION; SURVIVAL RATE; T-LYMPHOCYTES, REGULATORY;

EID: 84925350819     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.01.027     Document Type: Article

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