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Volumn 287, Issue 41, 2012, Pages 34157-34166

Impaired thymic export and increased apoptosis account for regulatory T cell defects in patients with non-ST segment elevation acute coronary syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE CORONARY SYNDROMES; ANNEXINS; CHEST PAIN; PERIPHERAL BLOOD; T CELL RECEPTOR; T CELLS; TREG CELLS;

EID: 84867266663     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.382978     Document Type: Article
Times cited : (56)

References (65)
  • 1
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G. K. (2005) Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352, 1685-1695
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 2
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. (2002) Inflammation in atherosclerosis. Nature 420, 868-874
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 7
    • 33750515883 scopus 로고    scopus 로고
    • Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice
    • DOI 10.1161/CIRCULATIONAHA.106.627430, PII 0000301720061031000014
    • Steffens, S., Burger, F., Pelli, G., Dean, Y., Elson, G., Kosco-Vilbois, M., Chatenoud, L., and Mach, F. (2006) Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice. Circulation 114, 1977-1984 (Pubitemid 44665393)
    • (2006) Circulation , vol.114 , Issue.18 , pp. 1977-1984
    • Steffens, S.1    Burger, F.2    Pelli, G.3    Dean, Y.4    Elson, G.5    Kosco-Vilbois, M.6    Chatenoud, L.7    Mach, F.8
  • 8
    • 72449195338 scopus 로고    scopus 로고
    • Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice
    • Sasaki, N., Yamashita, T., Takeda, M., Shinohara, M., Nakajima, K., Tawa, H., Usui, T., and Hirata, K. (2009) Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice. Circulation 120, 1996-2005
    • (2009) Circulation , vol.120 , pp. 1996-2005
    • Sasaki, N.1    Yamashita, T.2    Takeda, M.3    Shinohara, M.4    Nakajima, K.5    Tawa, H.6    Usui, T.7    Hirata, K.8
  • 11
    • 34247559732 scopus 로고    scopus 로고
    • Regulatory T-Cell Immunity in Atherosclerosis
    • DOI 10.1016/j.tcm.2007.03.001, PII S1050173807000473
    • Mallat, Z., Ait-Oufella, H., and Tedgui, A. (2007) Regulatory T-cell immunity in atherosclerosis. Trends Cardiovasc. Med. 17, 113-118 (Pubitemid 46670020)
    • (2007) Trends in Cardiovascular Medicine , vol.17 , Issue.4 , pp. 113-118
    • Mallat, Z.1    Ait-Oufella, H.2    Tedgui, A.3
  • 14
    • 34447638700 scopus 로고    scopus 로고
    • Frequency of naturally-occurring regulatory T cells is reduced in patients with ST-segment elevation myocardial infarction
    • DOI 10.1016/j.thromres.2006.12.005, PII S0049384806005111
    • Sardella, G., De Luca, L., Francavilla, V., Accapezzato, D., Mancone, M., Sirinian, M. I., Fedele, F., and Paroli, M. (2007) Frequency of naturally-occurring regulatory T cells is reduced in patients with ST-segment elevation myocardial infarction. Thromb. Res. 120, 631-634 (Pubitemid 47094917)
    • (2007) Thrombosis Research , vol.120 , Issue.4 , pp. 631-634
    • Sardella, G.1    De Luca, L.2    Francavilla, V.3    Accapezzato, D.4    Mancone, M.5    Sirinian, M.I.6    Fedele, F.7    Paroli, M.8
  • 17
    • 36348967350 scopus 로고    scopus 로고
    • Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions
    • de Boer, O. J., van der Meer, J. J., Teeling, P., van der Loos, C. M., and van der Wal, A. C. (2007) Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions. PLoS One 2, e779
    • (2007) PLoS One , vol.2
    • De Boer, O.J.1    Van Der Meer, J.J.2    Teeling, P.3    Van Der Loos, C.M.4    Van Der Wal, A.C.5
  • 18
    • 33846283803 scopus 로고    scopus 로고
    • + regulatory T cells express lower levels of the IL-7 receptor α chain (CD127), allowing consistent identification and sorting of live cells
    • + regulatory T cells express lower levels of the IL-7 receptor α chain (CD127), allowing consistent identification and sorting of live cells. J. Immunol. Methods 319, 41-52
    • (2007) J. Immunol. Methods , vol.319 , pp. 41-52
    • Hartigan-O'Connor, D.J.1    Poon, C.2    Sinclair, E.3    McCune, J.M.4
  • 21
    • 0023035568 scopus 로고
    • Induction of coronary artery spasm by acetylcholine in patients with variant angina: Possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm
    • Yasue, H., Horio, Y., Nakamura, N., Fujii, H., Imoto, N., Sonoda, R., Kugiyama, K., Obata, K., Morikami, Y., and Kimura, T. (1986) Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. Circulation 74, 955-963 (Pubitemid 17174941)
    • (1986) Circulation , vol.74 , Issue.5 , pp. 955-963
    • Yasue, H.1    Horio, Y.2    Nakamura, N.3
  • 22
    • 0036118126 scopus 로고    scopus 로고
    • Folic acid treatment reduces chemokine release from peripheral blood mononuclear cells in hyperhomocysteinemic subjects
    • DOI 10.1161/01.ATV.0000013288.35930.90
    • Holven, K. B., Aukrust, P., Holm, T., Ose, L., and Nenseter, M. S. (2002) Folic acid treatment reduces chemokine release from peripheral blood mononuclear cells in hyperhomocysteinemic subjects. Arterioscler. Thromb. Vasc. Biol. 22, 699-703 (Pubitemid 34408756)
    • (2002) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.22 , Issue.4 , pp. 699-703
    • Holven, K.B.1    Aukrust, P.2    Holm, T.3    Ose, L.4    Nenseter, M.S.5
  • 23
    • 33645451365 scopus 로고    scopus 로고
    • Analytical performance and diagnostic accuracy of immunometric assays for the measurement of circulating oxidized LDL
    • Holvoet, P., Macy, E., Landeloos, M., Jones, D., Jenny, N. S., Nancy, J. S., Van de Werf, F., and Tracy, R. P. (2006) Analytical performance and diagnostic accuracy of immunometric assays for the measurement of circulating oxidized LDL. Clin. Chem. 52, 760-764
    • (2006) Clin. Chem. , vol.52 , pp. 760-764
    • Holvoet, P.1    Macy, E.2    Landeloos, M.3    Jones, D.4    Jenny, N.S.5    Nancy, J.S.6    Van De Werf, F.7    Tracy, R.P.8
  • 24
    • 0035161658 scopus 로고    scopus 로고
    • T cell receptor excision circles as markers for recent thymic emigrants: Basic aspects, technical approach, and guidelines for interpretation
    • DOI 10.1007/s001090100271
    • Hazenberg, M. D., Verschuren, M. C., Hamann, D., Miedema, F., and van Dongen, J. J. (2001) T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation. J. Mol. Med. 79, 631-640 (Pubitemid 33071151)
    • (2001) Journal of Molecular Medicine , vol.79 , Issue.11 , pp. 631-640
    • Hazenberg, M.D.1    Verschuren, M.C.2    Hamann, D.3    Miedema, F.4    Dongen, J.J.5
  • 25
    • 33746754703 scopus 로고    scopus 로고
    • Ox-LDL induces apoptosis in human coronary artery endothelial cells: Role of PKC, PTK, bcl-2, and Fas
    • Li, D., Yang, B., and Mehta, J. L. (1998) Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas. Am. J. Physiol. Heart Circ. Physiol. 275, H568-H576 (Pubitemid 128734427)
    • (1998) American Journal of Physiology , vol.275 , Issue.2 PART 2
    • Dayuan, L.I.1    Yang, B.2    Mehta, J.L.3
  • 27
    • 0033043803 scopus 로고    scopus 로고
    • Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins
    • Meilhac, O., Escargueil-Blanc, I., Thiers, J. C., Salvayre, R., and Négre-Salvayre, A. (1999) Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins. FASEB J. 13, 485-494 (Pubitemid 29115566)
    • (1999) FASEB Journal , vol.13 , Issue.3 , pp. 485-494
    • Meilhac, O.1    Escargueil-Blanc, I.2    Thiers, J.-C.3    Salvayre, R.4    Negre-Salvayre, A.5
  • 28
  • 29
    • 77954242107 scopus 로고    scopus 로고
    • TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure
    • Kleinbongard, P., Heusch, G., and Schulz, R. (2010) TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure. Pharmacol. Ther. 127, 295-314
    • (2010) Pharmacol. Ther. , vol.127 , pp. 295-314
    • Kleinbongard, P.1    Heusch, G.2    Schulz, R.3
  • 30
    • 43449120940 scopus 로고    scopus 로고
    • Mechanisms of T regulatory cell function
    • Askenasy, N., Kaminitz, A., and Yarkoni, S. (2008) Mechanisms of T regulatory cell function. Autoimmun. Rev. 7, 370-375
    • (2008) Autoimmun. Rev. , vol.7 , pp. 370-375
    • Askenasy, N.1    Kaminitz, A.2    Yarkoni, S.3
  • 31
    • 0242403301 scopus 로고    scopus 로고
    • Quantification of regulatory T cells in patients with systemic lupus erythematosus
    • DOI 10.1016/S0896-8411(03)00121-5
    • Crispin, J. C., Martínez, A., and Alcocer-Varela, J. (2003) Quantification of regulatory T cells in patients with systemic lupus erythematosus. J. Autoimmun. 21, 273-276 (Pubitemid 37410115)
    • (2003) Journal of Autoimmunity , vol.21 , Issue.3 , pp. 273-276
    • Crispin, J.C.1    Martinez, A.2    Alcocer-Varela, J.3
  • 33
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
    • DOI 10.1084/jem.20040165
    • Ehrenstein, M. R., Evans, J. G., Singh, A., Moore, S., Warnes, G., Isenberg, D. A., and Mauri, C. (2004) Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy. J. Exp. Med. 200, 277-285 (Pubitemid 39031247)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.3 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 39
    • 0036838536 scopus 로고    scopus 로고
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169, 4712-4716
    • (2002) J. Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 47
    • 34548721641 scopus 로고    scopus 로고
    • Prevalence of newly generated naïve regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis
    • Haas, J., Fritzsching, B., Trübswetter, P., Korporal, M., Milkova, L., Fritz, B., Vobis, D., Krammer, P. H., Suri-Payer, E., and Wildemann, B. (2007) Prevalence of newly generated naïve regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis. J. Immunol. 179, 1322-1330
    • (2007) J. Immunol. , vol.179 , pp. 1322-1330
    • Haas, J.1    Fritzsching, B.2    Trübswetter, P.3    Korporal, M.4    Milkova, L.5    Fritz, B.6    Vobis, D.7    Krammer, P.H.8    Suri-Payer, E.9    Wildemann, B.10
  • 49
    • 0023765609 scopus 로고
    • Deletion of the human T-cell receptor δ-gene by a site-specific recombination
    • de Villartay, J. P., Hockett, R. D., Coran, D., Korsmeyer, S. J., and Cohen, D. I. (1988) Deletion of the human T-cell receptor δ-gene by a site-specific recombination. Nature 135, 170-174
    • (1988) Nature , vol.135 , pp. 170-174
    • De Villartay, J.P.1    Hockett, R.D.2    Coran, D.3    Korsmeyer, S.J.4    Cohen, D.I.5
  • 50
    • 0030069149 scopus 로고    scopus 로고
    • T-cell receptor α locus V(D)J recombination by-products are abundant in thymocytes and mature T cells
    • Livak, F., and Schatz, D. G. (1996) T-cell receptor α locus V(D)J recombination by-products are abundant in thymocytes and mature T cells. Mol. Cell. Biol. 16, 609-618 (Pubitemid 26029100)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.2 , pp. 609-618
    • Livak, F.1    Schatz, D.G.2
  • 54
    • 40149083895 scopus 로고    scopus 로고
    • Resistance to apoptosis and expansion of regulatory T cells in relation to the detection of circulating tumor cells in patients with metastatic epithelial cancer
    • DOI 10.1007/s10875-007-9139-2
    • Stanzer, S., Dandachi, N., Balic, M., Resel, M., Samonigg, H., and Bauernhofer, T. (2008) Resistance to apoptosis and expansion of regulatory T cells in relation to the detection of circulating tumor cells in patients with metastatic epithelial cancer. J. Clin. Immunol. 28, 107-114 (Pubitemid 351328949)
    • (2008) Journal of Clinical Immunology , vol.28 , Issue.2 , pp. 107-114
    • Stanzer, S.1    Dandachi, N.2    Balic, M.3    Resel, M.4    Samonigg, H.5    Bauernhofer, T.6
  • 58
    • 33751227462 scopus 로고    scopus 로고
    • Similar sensitivity of regulatory T cells towards CD95L-mediated apoptosis in patients with multiple sclerosis and healthy individuals
    • DOI 10.1016/j.jns.2006.09.006, PII S0022510X06003856
    • Fritzsching, B., Korporal, M., Haas, J., Krammer, P. H., Suri-Payer, E., and Wildemann, B. (2006) Similar sensitivity of regulatory T cells towards CD95L-mediated apoptosis in patients with multiple sclerosis and healthy individuals. J. Neurol. Sci. 251, 91-97 (Pubitemid 44792146)
    • (2006) Journal of the Neurological Sciences , vol.251 , Issue.1-2 , pp. 91-97
    • Fritzsching, B.1    Korporal, M.2    Haas, J.3    Krammer, P.H.4    Suri-Payer, E.5    Wildemann, B.6
  • 61
    • 52449114737 scopus 로고    scopus 로고
    • Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms
    • Loppnow, H., Werdan, K., and Buerke, M. (2008) Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms. Innate Immun. 14, 63-87
    • (2008) Innate Immun. , vol.14 , pp. 63-87
    • Loppnow, H.1    Werdan, K.2    Buerke, M.3
  • 62
    • 0035859839 scopus 로고    scopus 로고
    • Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina
    • Smith, D. A., Irving, S. D., Sheldon, J., Cole, D., and Kaski, J. C. (2001) Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina. Circulation 104, 746-749 (Pubitemid 32762668)
    • (2001) Circulation , vol.104 , Issue.7 , pp. 746-749
    • Smith, D.A.1    Irving, S.D.2    Sheldon, J.3    Cole, D.4    Kaski, J.C.5
  • 63
    • 0041827208 scopus 로고    scopus 로고
    • Serum tumour necrosis factor-α, interleukin-2 and interleukin-10 activation in stable angina and acute coronary syndromes
    • DOI 10.1097/00019501-200309000-00003
    • Mizia-Stec, K., Gasior, Z., Zahorska-Markiewicz, B., Janowska, J., Szulc, A., Jastrzebska-Maj, E., and Kobielusz-Gembala, I. (2003) Serum tumour necrosis factor-α, interleukin-2 and interleukin-10 activation in stable angina and acute coronary syndromes. Coron. Artery Dis. 14, 431-438 (Pubitemid 37070321)
    • (2003) Coronary Artery Disease , vol.14 , Issue.6 , pp. 431-438
    • Mizia-Stec, K.1    Gasior, Z.2    Zahorska-Markiewicz, B.3    Janowska, J.4    Szulc, A.5    Jastrzebska-Maj, E.6    Kobielusz-Gembala, I.7
  • 64
    • 70349974358 scopus 로고    scopus 로고
    • High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of interferon gamma and interleukin-10 post myocardial infarction
    • Patel, K. D., Duggan, S. P., Currid, C. A., Gallagher, W. M., McManus, R., Kelleher, D., Murphy, R. T., and Ryan, A. W. (2009) High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of interferon gamma and interleukin-10 post myocardial infarction. Clin. Immunol. 133, 251-256
    • (2009) Clin. Immunol. , vol.133 , pp. 251-256
    • Patel, K.D.1    Duggan, S.P.2    Currid, C.A.3    Gallagher, W.M.4    McManus, R.5    Kelleher, D.6    Murphy, R.T.7    Ryan, A.W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.