Insufficient deactivation of the protein tyrosine kinase lck amplifies t-cell responsiveness in acute coronary syndrome

Circulation Research

Volumn 106, Issue 4, 2010, Pages 769-778

  Pryshchep, Sergey ^a   Goronzy, Jörg J ^a,c   Parashar, Susmita ^b   Weyand, Cornelia M ^a,c  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium signaling; Protein tyrosine kinase; Signaling pathways; T cell

Indexed keywords

C REACTIVE PROTEIN; CALCIUM; CD3 ANTIGEN; CD4 ANTIGEN; CD45RO ANTIGEN; CYTOPLASM PROTEIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PHOSPHOTYROSINE; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; TYROSINE;

ACUTE CORONARY SYNDROME; ANTIGEN RECOGNITION; ARTICLE; ATHEROSCLEROTIC PLAQUE; BIOACCUMULATION; CALCIUM CELL LEVEL; CD4+ T LYMPHOCYTE; COMPLEX FORMATION; CONTROLLED STUDY; EFFECTOR CELL; ENZYME ACTIVATION; ENZYME INACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; MEMORY CELL; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ACUTE CORONARY SYNDROME; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD3; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCIUM SIGNALING; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; COCULTURE TECHNIQUES; ENTEROTOXINS; ENZYME ACTIVATION; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNOLOGICAL SYNAPSES; INFLAMMATION MEDIATORS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MALE; MIDDLE AGED; PHOSPHORYLATION; PHOSPHOTYROSINE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SUPERANTIGENS; TIME FACTORS; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 77949408555     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.206052     Document Type: Article

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