Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer's Disease Transgenic Mouse Model

Journal of Alzheimer's Disease

Volumn 45, Issue 2, 2015, Pages 639-650

  Zhang, Cheng ^a   Kuo, Ching Chang ^b   Moghadam, Setareh H ^a   Monte, Louise ^a   Rice, Kenner C ^c   Rissman, Robert A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF OREGON   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Alzheimer's disease; corticotropin releasing factor 1 receptor (CRFR1); glutathione; glutathione peroxide; glutathione reductase; oxidative stress; oxidized glutathione; R121919; S glutathionylated protein

Indexed keywords

3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; GLUTATHIONE; GLUTATHIONE DISULFIDE; PROTEIN S; AMYLOID PRECURSOR PROTEIN; CORTICOTROPIN RELEASING FACTOR; GLUTATHIONE PEROXIDASE; PRESENILIN 1; PYRIMIDINE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIORAL RESEARCH; CONTROLLED STUDY; DISEASE COURSE; FEMALE; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; DISEASE MODEL; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; SEX DIFFERENCE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CORTICOTROPIN-RELEASING HORMONE; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MUTATION; OXIDATIVE STRESS; PRESENILIN-1; PYRIMIDINES; SEX FACTORS; SIGNAL TRANSDUCTION;

EID: 84925348801     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-141722     Document Type: Article

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