Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor

Journal of Alzheimer's Disease

Volumn 43, Issue 3, 2015, Pages 967-976

  Campbell, Shannon N ^a   Zhang, Cheng ^a   Monte, Louise ^a   Roe, Allyson D ^a   Rice, Kenner C ^c   Taché, Yvette ^d,e   Masliah, Eliezer ^a,b   Rissman, Robert A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Alzheimer's disease; corticotropin releasing factor (CRF); corticotropin releasing factor receptor (CRFR); electron microscopy; hippocampus; immunohistochemistry; stress; tau phosphorylation (tau P); western blot

Indexed keywords

3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; STRESS ACTIVATED PROTEIN KINASE; TAU PROTEIN; CORTICOTROPIN RELEASING FACTOR RECEPTOR;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC STRESS; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; IMMUNOGOLD LABELING; MOUSE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; ANIMAL; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEINOSIS; TRANSGENIC MOUSE;

ANIMALS; CORTICOTROPIN-RELEASING HORMONE; HIPPOCAMPUS; MICE; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN AGGREGATION, PATHOLOGICAL; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; TAU PROTEINS;

EID: 84914694786     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-141281     Document Type: Article

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