Challenges in effect-directed analysis with a focus on biological samples

TrAC - Trends in Analytical Chemistry

Volumn 67, Issue , 2015, Pages 179-191

  Simon, Eszter ^a,c   Lamoree, Marja H ^b   Hamers, Timo ^b   de Boer, Jacob ^b  

^a BIODETECTION SYSTEMS B V   (Netherlands)

^b INSTITUTE FOR ENVIRONMENTAL STUDIES   (Netherlands)

^c SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

Author keywords

Bioassay; Bioavailability; Biological sample; Biota; Effect directed analysis; Exposome; Identification; Mixture effect; Sample preparation; Toxicity

Indexed keywords

BIOASSAY; BIOCHEMISTRY; BIOLOGICAL MATERIALS; CHEMICAL ANALYSIS; CHEMICAL COMPOUNDS; CHEMICAL DETECTION; IDENTIFICATION (CONTROL SYSTEMS); INDICATORS (CHEMICAL); MIXTURES; TISSUE;

BIOAVAILABILITY; BIOLOGICAL SAMPLES; BIOTA; EFFECT-DIRECTED ANALYSIS; EXPOSOME; MIXTURE EFFECTS; SAMPLE PREPARATION;

TOXICITY;

17ALPHA ESTRADIOL; 4 HYDROXYHEPTACHLOROSTYRENE; 4 TERT OCTYLPHENOL; CHLOROXYLENOL; CLOROFENE; DICHLOROPHEN; ENDOCRINE DISRUPTOR; EQUOL; ESTRADIOL; ETHINYLESTRADIOL; FLUORANTHENE; FLUORENE; METHYLBOLDENONE; METHYLTESTOSTERONE; METHYLTESTOSTERONE ACETATE; METHYLTESTOSTERONE PROPIONATE; NANDROLONE; OXYBENZONE; PHENANTHRENE; POLYCHLORINATED DIBENZOFURAN; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE; TESTOSTERONE 4 BUTYLCYCLOHEXANECARBOXYLATE; TESTOSTERONE ISOBUTYRATE; TESTOSTERONE PHENYLPROPIONATE; THYROID DISRUPTING CHEMICAL; THYROID HORMONE; TRICLOSAN; UNCLASSIFIED DRUG; WATER;

ACCURACY; AUTOMATION; BIOACCUMULATION; BIOASSAY; BIOAVAILABILITY; BLOOD; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONFORMATION; DUST; EFFECT DIRECTED ANALYSIS; FRACTIONATION; GENOTOXICITY; HIGH THROUGHPUT SCREENING; HORMONE ACTION; HOUSEHOLD; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; METABOLISM; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEDIMENT; SOLID PHASE EXTRACTION; TOXICITY TESTING; TREND STUDY; URINE;

EID: 84925266971     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2015.01.006     Document Type: Review

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