Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis

Analytical and Bioanalytical Chemistry

Volumn 394, Issue 5, 2009, Pages 1385-1397

  Weiss, Jana M ^a   Hamers, Timo ^a   Thomas, Kevin V ^b   Van Der Linden, Sander ^c   Leonards, Pim E G ^a   Lamoree, Marja H ^a  

^a INSTITUTE FOR ENVIRONMENTAL STUDIES   (Netherlands)

^b NORWEGIAN INSTITUTE FOR WATER RESEARCH   (Norway)

^c BIODETECTION SYSTEMS B V   (Netherlands)

Author keywords

Androgen receptor (AR); Androgenicity; Effect directed analysis (EDA); MODELKEY; Polycyclic aromatic hydrocarbons (PAHs); Sediment

Indexed keywords

ANDROGEN RECEPTOR (AR); ANDROGEN RECEPTOR ANTAGONISTS; ANDROGEN RECEPTORS; ANDROGENIC ACTIVITY; ANDROGENICITY; ANTI-ANDROGENIC; CHEMICAL IDENTIFICATION; CHEMICAL MIXTURES; CHEMICAL STRUCTURE; COMPLEX SAMPLES; DI-BUTYL PHTHALATE; DIHYDROTESTOSTERONE; DRY WEIGHT; EFFECT-DIRECTED ANALYSIS; EFFECT-DIRECTED ANALYSIS (EDA); ENDOCRINE DISRUPTERS; IN-VITRO; MASKING EFFECT; MODELKEY; NONYLPHENOL; POLYAROMATIC HYDROCARBONS; RIVER SEDIMENTS; SCREENING METHODS; SEDIMENT EXTRACTS; TECHNICAL MIXTURES;

CHROMATOGRAPHIC ANALYSIS; ESTERS; LIQUID CHROMATOGRAPHY; PHENOLS; POLYCYCLIC AROMATIC HYDROCARBONS; SEDIMENTOLOGY;

AROMATIC HYDROCARBONS;

ANDROGEN; ANTIANDROGEN;

BELGIUM; CHEMICAL STRUCTURE; CHEMISTRY; CONFERENCE PAPER; MASS FRAGMENTOGRAPHY; METABOLISM; RIVER; SEDIMENT;

ANDROGEN ANTAGONISTS; ANDROGENS; BELGIUM; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GEOLOGIC SEDIMENTS; MOLECULAR STRUCTURE; RIVERS;

EID: 67449146896     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-009-2807-8     Document Type: Conference Paper

References (43)

1. AK Hotchkiss CV Rider CR Blystone VS Wilson PC Hartig GT Ankley PM Foster CL Gray LE Gray 2008 Toxicol. Sci 105 235 259
2. WHO (2002) Global assessment of the state-of-the-science of endocrine disruptors. International Programme on Chemical Safety, Geneva, Switzerland
3. LJ Mills C Chichester 2005 Sci Total Environ 343 1 34
4. G Ankley E Mihaich R Stahl D Tillit T Colborn S McMaster R Miller J Bantle P Cambell N Denslow R Dickerson L Folmar M Fry J Giesy LE Gray P Guiney T Hutchinson S Kennedy V Kramer G LeBlanc M Mayes A Nimrod R Patino R Peterson R Purdy R Ringer P Thomas L Touart G van der Kraak T Zacharewski 1998 Environ Toxicol Chem 17 68 87
5. NH Yu ENM Ho DKK Leung TSM Wan 2005 J. Pharm. Biomed. Anal 37 1031 1038
6. RI Wood 2008 Front. Neuroendocrinol 29 490 506
7. HHD Meyer 2001 Acta Pathol. Microbiol. Immunol. Scand 109 1 8
8. LJG Gooren MCM Bunck 2004 Drugs 64 1861 1891
9. W Brack 2003 Anal Bioanal Chem 377 397 407
10. M Grung R Lichtenthaler M Ahel K-E Tollefsen K Langford KV Thomas 2007 Chemosphere 67 108 120
11. KV Thomas MR Hurst P Matthiessen M McHugh A Smith MJ Waldock 2002 Environ Toxicol Chem 21 1456 1461
12. KV Thomas JE Thain MJ Waldock 1999 Environ Sci Technol 18 401 411
13. R Urbatzka A Van Cauwenberge S Maggioni L Viganò A Mandich E Benfanati I Lutz W Kloas 2007 Chemosphere 67 1080 1087
14. CJ Houtman PH Cenijn T Hamers MH Lamoree J Legler AJ Murk A Brouwer 2004 Environ Toxicol Chem 23 32 40
15. CJ Houtman P Booij E Jover D del Rio Pascual K Swart M van Velzen R Vreuls J Legler A Brouwer MH Lamoree 2006 Chemosphere 65 2244 2252
16. M Grote W Brack R Altenburger 2005 Environ Toxicol 20 475 486
17. CJ Houtman AM van Oostveen A Brouwer MH Lamoree J Legler 2004 Environ Sci Technol 38 6415 6423
18. T-B Seiler T Schulze H Hollert 2008 Anal Bioanal Chem 390 1975 1985
19. Houtman CJ. Tracing endocrine disruptors-identification and effects of endocrine disrupting compounds in the aquatic environment. Thesis. 2007. Institute for Environmental Studies (IVM), VU University, Amsterdam, The Netherlands.
20. P Fernandez JM Bayona 1992 J Chromatogr 625 141 149
21. E Sonneveld HJ Jansen JAC Riteco A Brouwer B Van der Burg 2005 Toxicol Sci 83 136 148
22. W Brack M Schmitt-Jansen M Machala R Brix D Barceló E Schymanski G Streck T Schulze 2008 Anal Bioanal Chem 390 1959 1973
23. A Svenson A-S Allard 2004 Environ Toxicol 19 510 517
24. EL Schymanski C Meinert M Meringer W Brack (2008 Anal Chim Acta 615 136 147
25. J Falandysz T Albanis J Bachmann R Bettinetti I Bochentin V Boti S Bristeau B Daehne T Dagnac S Galassi R Jeannot J Oehlmann A Orlikowska V Sakkas R Szczerski V Valsamaki U Schulte-Oehlmann 2006 J Environ Sci Health Part A 41 2127 2162
26. E Mazurová K Hilscherová V Jálová HR Köhler R Triebskorn JP Giesy L Bláha 2008 Aquat Toxicol 89 172 179
27. AM Vinggaard C Hnida JC Larsen 2000 Toxicol 145 173 183
28. M Sanders S Sivertsen G Scott 2002 Arch Environ Contam Toxicol 43 438 448
29. HJ Lee S Chattopadhyay E-Y Gong RS Ahn K Lee 2003 Toxicol Sci 75 40 46
30. E Mylchreest M Sar RC Cattley PMD Foster 1999 Toxicol Appl Pharmacol 156 81 95
31. P Roy H Salminen P Koskimies J Simola A Smeds P Saukko IT Huhtaniemi 2004 J Steroid Biochem Mol Biol 88 157 166
32. S Takeuchi M Iida S Kobayashi K Jin T Matsuda H Kojima 2005 Toxicol 210 223 233
33. H Fang W Tong WS Branham CL Moland SL Dial H Hong Q Xie R Perkins W Owens DM Sheehan 2003 Chem Res Toxicol 16 1338 1358
34. E Sonneveld JAC Riteco HJ Jansen B Pieterse A Brouwer WG Schoonen B Van der Burg 2006 Toxicol Sci 89 173 187
35. IG Lange A Daxenberger B Schiffer H Witters D Ibaretta HHD Meyer 2002 Anal Chim Acta 473 27 37
36. EP Kolodziej JL Gray DL Sedlak 2003 Environ Toxicol Chem 22 2622 2629
37. LA Kirk CR Tyler CM Lye JP Sumpter 2002 Environ Toxicol Chem 21 972 979
38. HR Andersen AM Vinggaard TH Rasmussen IM Gjermandsen EC Bonefeld-Jørgensen 2002 Toxicol Appl Pharmacol 179 1 12
39. S Kitamura T Suzuki S Ohta N Fujimoto 2003 Environ Health Perspect 111 503 508
40. H Tamura SC Maness K Reischmann DC Dorman E Gray KW Gaido 2001 Toxicol Sci 60 56 62
41. L-C Xu L Liu X-M Ren M-R Zhang N Cong A-Q Xu J-H Shao 2008 Toxicol 243 59 65
42. P Sohoni JP Sumpter 1998 J Endocrin 158 327 339
43. SM Singh S Gauthier F Labrie 2000 Curr Med Chem 7 211 247