Oral omega-3 fatty acid treatment for dry eye in contact lens wearers

Cornea

Volumn 34, Issue 4, 2015, Pages 413-420

  Bhargava, Rahul ^a   Kumar, Prachi ^b  

^a Laser Eye Clinic   (India)

^b SANTOSH MEDICAL COLLEGE   (India)

Author keywords

conjunctival impression cytology; contact lens; dry eye syndrome; omega 3 fatty acids

Indexed keywords

CORN OIL; OMEGA 3 FATTY ACID; PLACEBO; MICROCAPSULE;

ARTICLE; BLURRED VISION; BURNING SENSATION; CELL COUNT; COMFORT; CONTACT LENS; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; DRY EYE; EYE EXAMINATION; EYE REDNESS; FATIGUE; FEMALE; GOBLET CELL; HUMAN; IMPRESSION CYTOLOGY; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SCHIRMER TEST; SLIT LAMP; TREATMENT DURATION; VISUAL ACUITY; ADVERSE EFFECTS; CHEMISTRY; CLINICAL TRIAL; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOLOGY; DRY EYE SYNDROMES; LACRIMAL FLUID; MICROCAPSULE; ORAL DRUG ADMINISTRATION; PATHOPHYSIOLOGY;

ADMINISTRATION, ORAL; CAPSULES; CELL COUNT; CONTACT LENSES; DOUBLE-BLIND METHOD; DRY EYE SYNDROMES; EPITHELIUM, CORNEAL; FATTY ACIDS, OMEGA-3; FEMALE; GOBLET CELLS; HUMANS; INTERVENTION STUDIES; PROSPECTIVE STUDIES; QUESTIONNAIRES; TEARS;

EID: 84925214146     PISSN: 02773740     EISSN: 15364798     Source Type: Journal    
DOI: 10.1097/ICO.0000000000000386     Document Type: Article

References (32)

1. Dillehay SM. Does the level of available oxygen impact comfort in contact lens wear?: A review of the literature. Eye Contact Lens. 2007; 33:148-155.
2. Rohit A, Willcox M, Stapleton F. Tear lipid layer and contact lens comfort: a review. Eye Contact Lens. 2013;39:247-253.
3. Sengor T, Aydin Kurna S, Ozbay N, et al. Contact lens-related dry eye and ocular surface changes with mapping technique in long-term soft silicone hydrogel contact lens wearers. Eur J Ophthalmol. 2012;22: S17-S23.
4. Doughty MJ. Objective assessment of squamous metaplasia of conjunctival epithelial cells as associated with soft contact lens wear versus nonlens wearers. Cornea. 2014;33:1095-1102.
5. Cakmak SS, Unlü MK, Karaca C, et al. Effects of soft contact lenses on conjunctival surface. Eye Contact Lens. 2003;29:230-233.
6. Tomatir DK, Erda N, Gürlü VP. Effects of different contact lens materials and contact lens-wearing periods on conjunctival cytology in asymptomatic contact lens wearers. Eye Contact Lens. 2008;34:166-168.
7. Pisella PJ, Malet F, Lejeune S, et al. Ocular surface changes induced by contact lens wear. Cornea. 2001;20:820-825.
8. Doughty MJ. Contact lens wear and the development of squamous metaplasia of the surface cells of the conjunctiva. Eye Contact Lens. 2011;37:274-281.
9. Lopin E, Deveney T, Asbell PA. Impression cytology: recent advances and applications in dry eye disease. Ocul Surf. 2009;7:93-110.
10. Kumar P, Bhargava R, Kumar M, et al. The correlation of routine tear function tests and conjunctival impression cytology in dry eye syndrome. Korean J Ophthalmol. 2014;28:122-129.
11. Merle BM, Benlian P, Puche N, et al; Nutritional AMD Treatment 2 Study Group. Circulating omega-3 fatty acids and neovascular agerelated macular degeneration. Invest Ophthalmol Vis Sci. 2014;55: 2010-2019.
12. Kumar P, Bhargava R, Kumar M, et al. Dry eye syndrome: a diagnostic enigma. Int J Contemp Surg. 2013;1:72-77.
13. Bhargava R, Kumar P, Kaur A, et al. The diagnostic value and accuracy of conjunctival impression cytology, dry eye symptomatology, and routine tear function tests in computer users. J Lab Physicians. 2014;6: 102-108.
14. Bhargava R, Kumar P, Kumar M, et al. A randomized controlled trial of omega-3 fatty acids in dry eye syndrome. Int J Ophthalmol. 2013;6: 811-816.
15. Shrestha E, Shrestha JK, Shayami G, et al. The conjunctival impression cytology between the diagnosed cases of dry eye and normal individuals. Nepal J Ophthalmol. 2011;3:39-44.
16. Nelson JD, Havener VR, Cameron JD. Cellulose acetate impressions of the ocular surface. Dry eye states. Arch Ophthalmol. 1983;101: 1869-1872.
17. Rolando M, Barabino S, Mingari C, et al. Distribution of conjunctival HLA-DR expression and the pathogenesis of damage in early dry eyes. Cornea. 2005;24:951-954.
18. Rosenberg ES, Asbell PA. Essential fatty acids in the treatment of dry eye. Ocul Surf. 2010;8:18-28.
19. Calder PC. Polyunsaturated fatty acids, inflammation, and immunity. Lipids. 2001;36:1007-1024.
20. Roncone M, Bartlett H, Eperjesi F. Essential fatty acids for dry eye: a review. Cont Lens Anterior Eye. 2010;33:49-54.
21. Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother. 2002;56:365-379.
22. Jakhar KA, Pal AK, Reddy DA, et al. Fatty acids composition of some selected Indian fishes. Afr J Basic Appl Sci. 2012;4:155-160.
23. Kokke KH, Morris JA, Lawrenson JG. Oral omega-6 essential fatty acid treatment in contact lens associated dry eye. Cont Lens Anterior Eye. 2008;31:141-146.
24. Harbige LS. Fatty acids, the immune response, and autoimmunity: a question of n-6 essentiality and the balance between n-6 and n-3. Lipids. 2003;38:323-341.
25. De Craen AJ, Tijssen JG, Kleijnen J. Is there a need to control the placebo in placebo controlled trials? Heart. 1997;77:95-96.
26. Kessing SV. Mucous gland system of the conjunctiva. A quantitative normal anatomical study. Acta Ophthalmol (Copenh). 1968;95:1.
27. Doughty MJ. Goblet cells of the normal human bulbar conjunctiva and their assessment by impression cytology sampling. Ocul Surf. 2012;10: 149-169.
28. Doughty MJ. Sampling area selection for the assessment of goblet cell density from conjunctival impression cytology specimens. Eye Contact Lens. 2012;38:122-129.
29. Creuzot C, Passemard M, Viau S, et al. Improvement of dry eye symptoms with polyunsaturated fatty acids [in French]. J Fr Ophtalmol. 2006;29:868-873.
30. Wojtowicz JC, Butovich I, Uchiyama E, et al. Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye. Cornea. 2011;30:308-314.
31. Oleñik A, Jiménez-Alfaro I, Alejandre-Alba N, et al. A randomized, double-masked study to evaluate the effect of omega-3 fatty acids supplementation in meibomian gland dysfunction. Clin Interv Aging. 2013;8:1133-1138.
32. Kangari H, Eftekhari MH, Sardari S, et al. Short-term consumption of oral omega-3 and dry eye syndrome. Ophthalmology. 2013;120: 2191-2196.