Superantigens of Staphylococcus aureus from patients with diabetic foot ulcers

Journal of Infectious Diseases

Volumn 210, Issue 12, 2014, Pages 1920-1927

  Vu, Bao G ^a   Stach, Christopher S ^a   Salgado Pabón, Wilmara ^a   Diekema, Daniel J ^a   Gardner, Sue E ^b   Schlievert, Patrick M ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA COLLEGE OF NURSING   (United States)

Author keywords

Diabetic foot ulcers; Methicillin resistance; Staphylococcus aureus; Superantigens; toxin

Indexed keywords

ALPHA TOXIN; BACTERIAL TOXIN; ENTEROTOXIN; PENICILLIN BINDING PROTEIN 2A; SUPERANTIGEN; TOXIC SHOCK SYNDROME TOXIN 1; TOXIN SEB; TOXIN SEC; UNCLASSIFIED DRUG; HEMOLYSIN; STAPHYLOCOCCAL ALPHA-TOXIN;

ARTICLE; ATOPIC DERMATITIS; BACTERIAL GENE; BACTERIUM ISOLATE; CELLULAR DISTRIBUTION; CHROMOSOMAL LOCALIZATION; CLINICAL ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETIC FOOT; GENE CLUSTER; HUMAN; MECA GENE; NONHUMAN; PENICILLIN RESISTANCE; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SAG GENE; SELX GENE; SKIN DEFECT; STAPHYLOCOCCUS AUREUS; TSTH GENE; VAGINA MUCOSA; CHEMISTRY; COMPARATIVE STUDY; FEMALE; GENETICS; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; STAPHYLOCOCCUS INFECTION; ULCER;

BACTERIAL TOXINS; DIABETIC FOOT; FEMALE; HEMOLYSIN PROTEINS; HUMANS; MALE; POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS; ULCER;

EID: 84925145687     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu350     Document Type: Article

References (39)

1. Gardner SE, Frantz RA. Wound bioburden and infection-related complications in diabetic foot ulcers. Biol Res Nurs 2008;10:44-53.
2. Robbins JM, Strauss G, Aron D, Long J, Kuba J, Kaplan Y. Mortality rates and diabetic foot ulcers: is it time to communicate mortality risk to patients with diabetic foot ulceration? J Am Podiatr Med Assoc 2008;98:489-93.
3. Wukich DK, Hobizal KB, Brooks MM. Severity of diabetic foot infection and rate of limb salvage. Foot Ankle Int 2013;34:351-8.
4. Carls GS, Gibson TB, Driver VR, et al. The economic value of specialized lower-extremity medical care by podiatric physicians in the treatment of diabetic foot ulcers. J Am Podiatr Med Assoc 2011;101:93-115.
5. Driver VR, Fabbi M, Lavery LA, Gibbons G. The costs of diabetic foot: the economic case for the limb salvage team. J Vasc Surg 2010;52:17S-22S.
6. Ge Y, MacDonald D, Hait H, Lipsky B, Zasloff M, Holroyd K. Microbiological profile of infected diabetic foot ulcers. Diabetic Med 2002;19:1032-4.
7. Gardner SE, Hillis SL, Heilmann K, Segre JA, Grice EA. The neuropathic diabetic foot ulcer microbiome is associated with clinical factors. Diabetes 2013;62:923-30.
8. Lowy FD. Staphylococcus aureus infections. N Engl J Med 1998;339:520-32.
9. Spaulding AR, Salgado-Pabon W, Kohler PA, Horswill AR, Leung D Y M, Schlievert PM. Staphylococcal and streptococcal superantigen exotoxins. Clin Microbiol Rev 2013;26:422-47.
10. Lina G, Bohach GA, Nair SP, Hiramatsu K, Jouvin-Marche E, Mariuzza R. Standard nomenclature for the superantigens expressed by Staphylococcus. J Infect Dis 2004;189:2334-6.
11. Wilson GJ, Seo KS, Cartwright RA, et al. A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia. PLoS Pathog 2011;7:e1002271.
12. Dinges MM, Orwin PM, Schlievert PM. Exotoxins of Staphylococcus aureus. Clin Microbiol Rev 2000;13:16-34.
13. Brosnahan AJ, Schlievert PM. Gram positive bacterial superantigen outside-in signaling causes toxic shock syndrome. FEBS J 2011;278:4649-67.
14. Schlievert PM, Case LC, Strandberg KL, Abrams BB, Leung DY. Superantigen profile of Staphylococcus aureus isolates from patients with steroid-resistant atopic dermatitis. Clin Infect Dis 2008;46:1562-7.
15. Gardner SE, Frantz RA, Saltzman CL, Hillis SL, Park H, Scherubel M. Diagnostic validity of three swab techniques for identifying chronic wound infection. Wound Rep Regen 2006;14:548-57.
16. Gardner SE, Frantz RA, Saltzman CL. Diagnostic validity of three quantitative swab techniques. Presented at: 28th Annual Nursing Research Conference (St. Louis, MO), 2004.
17. Schlievert PM, Case LC, Strandberg KL, Tripp TJ, Lin YC, Peterson ML. Vaginal Staphylococcus aureus superantigen profile shift from 1980 and 1981 to 2003, 2004, and 2005. J Clin Microbiol 2007;45:2704-7.
18. Salgado-Pabon W, Case-Cook LC, Schlievert PM. Molecular analysis of staphylococcal superantigens. Met Mol Biol 2014;1085:169-85.
19. Schlievert PM. Immunochemical assays for toxic shock syndrome toxin-1. Met Enzymol 1988;165:339-44.
20. Blake MS, Johnston KH, Russell-Jones GJ, Gotschlich EC. A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots. Anal Biochem 1984;136:175-9.
21. Pfaller MA, Caliendo AM, Versalovic J. Chromosomal restriction fragment analysis by pulsed-field gel electrophoresis: application to molecular epidemiology. In: Clinical microbiology procedures handbook. 3rd ed. Washington, DC: ASM Press, 2010:12.4.5.1-7.
22. McDougal LK, Steward CD, Killgore GE, Chaitram JM, McAllister SK, Tenover FC. Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database. J Clin Microbiol 2003;41:5113-20.
23. Eleftheriadou I, Tentolouris N, Argiana V, Jude E, Boulton AJ. Methicillin-resistant Staphylococcus aureus in diabetic foot infections. Drugs 2010;70:1785-97.
24. Subedi A, Ubeda C, Adhikari RP, Penades JR, Novick RP. Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock. Microbiology 2007;153:3235-45.
25. Bhakdi S, Tranum-Jensen J. Alpha-toxin of Staphylococcus aureus. Microbiol Rev 1991;55:733-51.
26. Peterson ML, Ault K, Kremer MJ, et al. The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1. Infect Immun 2005;73:2164-74.
27. Lin YC, Anderson MJ, Kohler PL, et al. Proinflammatory exoprotein characterization of toxic shock syndrome Staphylococcus aureus. Biochemistry 2011;50:7157-67.
28. Nienaber JJ, Sharma Kuinkel BK, Clarke-Pearson M, et al. Methicillinsusceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins. J Infect Dis 2011;204:704-13.
29. Kuehnert MJ, Kruszon-Moran D, Hill HA, et al. Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002. J Infect Dis 2006;193:172-9.
30. Mody L, Kauffman CA, Donabedian S, Zervos M, Bradley SF. Epidemiology of Staphylococcus aureus colonization in nursing home residents. Clin Infect Dis 2008;46:1368-73.
31. Redel H, Gao Z, Li H, et al. Quantitation and composition of cutaneous microbiota in diabetic and nondiabetic men. J Infect Dis 2013;207:1105-14.
32. Diegelmann RF, Evans MC. Wound healing: an overview of acute, fibrotic and delayed healing. Front Biosci 2004;9:283-9.
33. Parsonnet J, Hansmann MA, Delaney ML, et al. Prevalence of toxic shock syndrome toxin 1-producing Staphylococcus aureus and the presence of antibodies to this superantigen in menstruating women. J Clin Microbiol 2005;43:4628-34.
34. Osterholm MT, Davis JP, Gibson RW, et al. Tri-state toxic-state syndrome study. I. Epidemiologic findings. J Infect Dis 1982;145:431-40.
35. Lee HW, Kim SM, Kim JM, et al. Potential immunoinflammatory role of staphylococcal enterotoxin A in atopic dermatitis: immunohistopathological analysis and in vitro assay. Ann Dermatol 2013;25:173-80.
36. Collery MM, Smyth DS, Tumilty JJ, Twohig JM, Smyth CJ. Associations between enterotoxin gene cluster types egc1, egc2 and egc3, agr types, enterotoxin and enterotoxin-like gene profiles, and molecular typing characteristics of human nasal carriage and animal isolates of Staphylococcus aureus. J Med Microbiol 2009;58:13-25.
37. Varshney AK, Mediavilla JR, Robiou N, et al. Diverse enterotoxin gene profiles among clonal complexes of Staphylococcus aureus isolates from the Bronx, New York. Appl Environ Microbiol 2009;75:6839-49.
38. Vicosa GN, Le Loir A, Le Loir Y, de Carvalho AF, Nero LA. egc characterization of enterotoxigenic Staphylococcus aureus isolates obtained from raw milk and cheese. Int J Food Microbiol 2013;165:227-30.
39. Argudin MA, Mendoza MC, Rodicio MR. Food poisoning and Staphylococcus aureus enterotoxins. Toxins 2010;2:1751-73.