Potential immunoinflammatory role of staphylococcal enterotoxin a in atopic dermatitis: Immunohistopathological analysis and in vitro assay

Annals of Dermatology

Volumn 25, Issue 2, 2013, Pages 173-180

  Lee, Hee Woo ^a   Kim, Sung Min ^b   Kim, Jung Min ^b   Oh, Byung Min ^c   Kim, Jun Young ^c   Jung, Han Jin ^c   Lim, Hyun Jung ^c   Kim, Byung Soo ^d,e   Lee, Weon Ju ^c   Lee, Seok Jong ^c   Kim, Do Won ^c,f  

^a Seoul National University   (South Korea)

^b Department of Microbiology ^*  (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d Pusan National University School of Medicine   (South Korea)

^e Pusan National University School of Medicine   (South Korea)

^f Kyungpook National University Hospital   (South Korea)

Author keywords

Atopic dermatitis; Staphylococcal enterotoxin A; Staphylococcus Aureus

Indexed keywords

EID: 84878573653     PISSN: 10139087     EISSN: 20053894     Source Type: Journal    
DOI: 10.5021/ad.2013.25.2.173     Document Type: Article

References (15)

1. Ricci G, Patrizi A, Neri I, Bendandi B, Masi M. Frequency and clinical role of Staphylococcus aureus overinfection in atopic dermatitis in children. Pediatr Dermatol 2003;20:389-392.
2. Hauser C, Wuethrich B, Matter L, Wilhelm JA, Sonnabend W, Schopfer K. Staphylococcus aureus skin colonization in atopic dermatitis patients. Dermatologica 1985;170:35-39.
3. Hanifin JM, Rogge JL. Staphylococcal infections in patients with atopic dermatitis. Arch Dermatol 1977;113:1383-1386.
4. Aly R, Maibach HI, Shinefield HR. Microbial flora of atopic dermatitis. Arch Dermatol 1977;113:780-782.
5. Kim KH, Han JH, Chung JH, Cho KH, Eun HC. Role of staphylococcal superantigen in atopic dermatitis: influence on keratinocytes. J Korean Med Sci 2006;21:315-323.
6. Kim DW, Park JY, Park KD, Kim TH, Lee WJ, Lee SJ, et al. Are there predominant strains and toxins of Staphylococcus aureus in atopic dermatitis patients? Genotypic characterization and toxin determination of S. aureus isolated in adolescent and adult patients with atopic dermatitis. J Dermatol 2009;36:75-81.
7. Kim BS, Kim JY, Lim HJ, Lee WJ, Lee SJ, Kim JM, et al. Colonizing features of Staphylococcus aureus in early childhood atopic dermatitis and in mothers: a cross-sectional comparative study done at four kindergartens in Daegu, South Korea. Ann Allergy Asthma Immunol 2011;106:323-329.
8. Jiang XY, Wang CF, Wang CF, Zhang PJ, He ZY. Cloning and expression of Mycobacterium bovis secreted protein MPB83 in Escherichia coli. J Biochem Mol Biol 2006;39: 22-25.
9. DeDent AC, McAdow M, Schneewind O. Distribution of protein A on the surface of Staphylococcus aureus. J Bacteriol 2007;189:4473-4484.
10. Leung DYM, Eichenfield LF, Boguniewicz M. Atopic dermatitis (Atopic eczema). In: Wolff K, Goldsmith LA, Katz Sl, Gilchrest BA, Paller AS, Leffell DJ, editors. Fitzpatrick's dermatology in general medicine. Vol. 2. 7th ed. New York: McGraw-Hill Medical Cop., 2008:146-158.
11. Gröne A. Keratinocytes and cytokines. Vet Immunol Immunopathol 2002;88:1-12.
12. Yoshizumi M, Nakamura T, Kato M, Ishioka T, Kozawa K, Wakamatsu K, et al. Release of cytokines/chemokines and cell death in UVB-irradiated human keratinocytes, HaCaT. Cell Biol Int 2008;32:1405-1411.
13. Matsunaga T, Katayama I, Yokozeki H, Nishioka K. Superantigen-induced cytokine expression in organ-cultured human skin. J Dermatol Sci 1996;11:104-110.
14. Saloga J, Leung DY, Reardon C, Giorno RC, Born W, Gelfand EW. Cutaneous exposure to the superantigen staphylococcal enterotoxin B elicits a T-cell-dependent inflammatory response. J Invest Dermatol 1996;106:982-988.
15. Pivarcsi A, Gombert M, Dieu-Nosjean MC, Lauerma A, Kubitza R, Meller S, et al. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. J Immunol 2004;173:5810-5817.