Cognitive intervention in early psychosis - preserving abilities versus remediating deficits

Current Opinion in Behavioral Sciences

Volumn 4, Issue , 2015, Pages 63-72

  Pantelis, Christos ^a   Wannan, Cassandra ^a   Bartholomeusz, Cali F ^a,b   Allott, Kelly ^b   McGorry, Patrick D ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; APTITUDE; ASSOCIATIVE MEMORY; BRAIN MATURATION; COGNITIVE DEFECT; COGNITIVE DEVELOPMENT; COGNITIVE REHABILITATION; COGNITIVE THERAPY; COPING BEHAVIOR; DETERIORATION; DISABILITY; EARLY INTERVENTION; EXECUTIVE FUNCTION; GRAY MATTER; HUMAN; LANGUAGE PROCESSING; NUCLEAR MAGNETIC RESONANCE IMAGING; PSYCHOSIS; REVIEW; SCHIZOPHRENIA; SKILL; SOCIAL COGNITION; SOCIAL INTERACTION; VISUAL MEMORY; WISCONSIN CARD SORTING TEST; WORKING MEMORY;

EID: 84925082251     PISSN: None     EISSN: 23521546     Source Type: Journal    
DOI: 10.1016/j.cobeha.2015.02.008     Document Type: Review

References (97)

1. McGorry P.D. Issues for DSM-V: clinical staging: a heuristic pathway to valid nosology and safer, more effective treatment in psychiatry. Am J Psychiatry 2007, 164:859-860.
2. McGorry P.D., et al. Clinical staging: a heuristic model for psychiatry and youth mental health. Med J Aust 2007, 187(7 Suppl):S40-S42.
3. Birchwood M., Todd P., Jackson C. Early intervention in psychosis. The critical period hypothesis. Br J Psychiatry Suppl 1998, 172:53-59.
4. Malla A., Payne J. First-episode psychosis: psychopathology, quality of life, and functional outcome. Schizophr Bull 2005, 31:650-671.
5. Harvey P.D., Bellack A.S. Toward a terminology for functional recovery in schizophrenia: is functional remission a viable concept?. Schizophr Bull 2009, 35:300-306.
6. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987, 44:660-669.
7. Murray R.M., Lewis S.W. Is schizophrenia a neurodevelopmental disorder?. Br Med J: Clin Res Ed 1987, 295:681-682.
8. Rapoport J.L., Giedd J.N., Gogtay N. Neurodevelopmental model of schizophrenia: update 2012. Mol Psychiatry 2012, 17:1228-1238.
9. Insel T.R. Rethinking schizophrenia. Nature 2010, 468:187-193.
10. Pantelis C., et al. Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia. Schizophr Bull 2005, 31:672-696.
11. Pantelis C., et al. Neurobiological markers of illness onset in psychosis and schizophrenia: the search for a moving target. Neuropsychol Rev 2009, 19:385-398.
12. Pantelis C., et al. Attentional set-shifting ability in first-episode and established schizophrenia: relationship to working memory. Schizophr Res 2009, 112:104-113.
13. Howes O.D., Murray R.M. Schizophrenia: an integrated sociodevelopmental-cognitive model. Lancet 2014, 383:1677-1687.
14. Sowell E.R., et al. Mapping cortical change across the human life span. Nat Neurosci 2003, 6:309-315.
15. Pfefferbaum A., et al. A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch Neurol 1994, 51:874-887.
16. Gogtay N., et al. Age of onset of schizophrenia: perspectives from structural neuroimaging studies. Schizophr Bull 2011, 37:504-513.
17. Paus T., Keshavan M., Giedd J.N. Why do many psychiatric disorders emerge during adolescence?. Nat Rev Neurosci 2008, 9:947-957.
18. Steinberg L. Cognitive and affective development in adolescence. Trends Cogn Sci 2005, 9:69-74.
19. Paus T. Mapping brain maturation and cognitive development during adolescence. Trends Cogn Sci 2005, 9:60-68.
20. Morgan V., et al. People living with psychotic illness 2010: report on the second Australian national survey 2011, Department of Health and Ageing, Canberra, Australia.
21. Moises H.W., Zoega T., Gottesman I.I. The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia. BMC Psychiatry 2002, 2:8.
22. Aas M., et al. A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation. Front Psychiatry 2014, 4:182.
23. Bora E., Murray R.M. Meta-analysis of cognitive deficits in ultra-high risk to psychosis and first-episode psychosis: do the cognitive deficits progress over, or after, the onset of psychosis?. Schizophr Bull 2014, 40:744-755.
24. Mesholam-Gately R.I., et al. Neurocognition in first-episode schizophrenia: a meta-analytic review. Neuropsychology 2009, 23:315-336.
25. Seidman L.J., et al. Neuropsychology of the prodrome to psychosis in the NAPLS consortium: relationship to family history and conversion to psychosis. Arch Gen Psychiatry 2010, 67:578-588.
26. Palmer B.W., et al. Is it possible to be schizophrenic yet neuropsychologically normal?. Neuropsychology 1997, 11:437-446.
27. Gonzalez-Blanch C., et al. First-episode schizophrenia patients neuropsychologically within the normal limits: evidence of deterioration in speed of processing. Schizophr Res 2010, 119:18-26.
28. Kremen W.S., et al. The paradox of normal neuropsychological function in schizophrenia. J Abnorm Psychol 2000, 109:743-752.
29. Bozikas V.P., Andreou C. Longitudinal studies of cognition in first episode psychosis: a systematic review of the literature. Aust N Z J Psychiatry 2011, 45:93-108.
30. Barder H.E., et al. Ten year neurocognitive trajectories in first-episode psychosis. Front Hum Neurosci 2013, 7:643.
31. Barnett J.H., et al. Assessing cognitive function in clinical trials of schizophrenia. Neurosci Biobehav Rev 2010, 34:1161-1177.
32. Elliott R., et al. Neuropsychological evidence for frontostriatal dysfunction in schizophrenia. Psychol Med 1995, 25:619-630.
33. Downes J.J., et al. Impaired extra-dimensional shift performance in medicated and unmedicated Parkinson's disease: evidence for a specific attentional dysfunction. Neuropsychologia 1989, 27:1329-1343.
34. Pantelis C., et al. Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage. Schizophr Res 1999, 37:251-270.
35. Jazbec S., et al. Intra-dimensional/extra-dimensional set-shifting performance in schizophrenia: impact of distractors. Schizophr Res 2007, 89:339-349.
36. Ceaser A.E., et al. Set-shifting ability and schizophrenia: a marker of clinical illness or an intermediate phenotype?. Biol Psychiatry 2008, 64:782-788.
37. Donohoe G., et al. Are relational style and neuropsychological performance predictors of social attributions in chronic schizophrenia?. Psychiatry Res 2008, 161:19-27.
38. Hutton S.B., et al. Executive function in first-episode schizophrenia. Psychol Med 1998, 28:463-473.
39. Hilti C.C., et al. Sustained attention and planning deficits but intact attentional set-shifting in neuroleptic-naive first-episode schizophrenia patients. Neuropsychobiology 2010, 61:79-86.
40. Leeson V.C., et al. The relationship between IQ, memory, executive function, and processing speed in recent-onset psychosis: 1-year stability and clinical outcome. Schizophr Bull 2010, 36:400-409.
41. Bartok E., et al. Cognitive functions in prepsychotic patients. Prog Neuropsychopharmacol Biol Psychiatry 2005, 29:621-625.
42. Wood S.J., et al. Visuospatial memory and learning in first-episode schizophreniform psychosis and established schizophrenia: a functional correlate of hippocampal pathology?. Psychol Med 2002, 32:429-438.
43. Collie A., et al. Selectively impaired associative learning in older people with cognitive decline. J Cogn Neurosci 2002, 14:484-492.
44. Ongur D., et al. The neural basis of relational memory deficits in schizophrenia. Arch Gen Psychiatry 2006, 63:356-365.
45. Armstrong K., Williams L.E., Heckers S. Revised associative inference paradigm confirms relational memory impairment in schizophrenia. Neuropsychology 2012, 26:451-458.
46. Bartholomeusz C.F., et al. Relational memory in first episode psychosis: implications for progressive hippocampal dysfunction after illness onset. Aust N Z J Psychiatry 2011, 45:206-213.
47. Williams L.E., et al. Intact relational memory and normal hippocampal structure in the early stage of psychosis. Biol Psychiatry 2012, 71:105-113.
48. Fusar-Poli P., et al. Spatial working memory in individuals at high risk for psychosis: longitudinal fMRI study. Schizophr Res 2010, 123:45-52.
49. Simpson L. General intellectual ability and memory in people at high risk of developing psychosis and those early in their first episode of a psychotic illness 2003, (unpublished D.Clin.Neuropsych. thesis).
50. Pantelis C., et al. Should we redefine the concept of endophenotype in schizophrenia?. Rev Bras Psiquiatr 2010, 32:106-107.
51. Wood S.J., et al. Spatial working memory ability is a marker of risk-for-psychosis. Psychol Med 2003, 33:1239-1247.
52. Pantelis C., et al.: Progressive decline in attentional set-shifting ability in first episode schizophrenia: a 7-year follow-up study (submitted for publication).
53. De Luca C.R., et al. Normative data from the CANTAB. I: development of executive function over the lifespan. J Clin Exp Neuropsychol 2003, 25:242-254.
54. Sun D., et al. Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Mol Psychiatry 2009, 14:976-986.
55. Sun D., et al. Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals. Schizophr Res 2009, 108:85-92.
56. Pantelis C., et al. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet 2003, 361:281-288.
57. Job D.E., et al. Grey matter changes over time in high risk subjects developing schizophrenia. Neuroimage 2005, 25:1023-1030.
58. Tognin S., et al. Using structural neuroimaging to make quantitative predictions of symptom progression in individuals at ultra-high risk for psychosis. Front Psychiatry 2013, 4:187.
59. Cannon T.D., et al. Progressive reduction in cortical thickness as psychosis develops: a multisite longitudinal neuroimaging study of youth at elevated clinical risk. Biol Psychiatry 2014.
60. Gogtay N., et al. Cortical brain development in nonpsychotic siblings of patients with childhood-onset schizophrenia. Arch Gen Psychiatry 2007, 64:772-780.
61. Mattai A.A., et al. Normalization of cortical gray matter deficits in nonpsychotic siblings of patients with childhood-onset schizophrenia. J Am Acad Child Adolesc Psychiatry 2011, 50:697-704.
62. Zalesky A., et al. Delayed development of brain connectivity in children with schizophrenia and their nonpsychotic siblings. JAMA Psychiatry 2015, (in press, 18.02.15).
63. Pantelis C., Bartholomeusz C.F. Social neuroscience in psychiatry: pathways to discovering neurobiological risk and resilience. World Psychiatry 2014, 13:146-147.
64. Katagiri N., et al. A longitudinal study investigating sub-threshold symptoms and brain changes in individuals with an 'At Risk Mental State' (ARMS). Schizophr Res 2015, (in press, 03.01.2015). 10.1016/j.schres.2015.01.002.
65. Velligan D.I., Bow-Thomas C.C. Two case studies of cognitive adaptation training for outpatients with schizophrenia. Psychiatr Serv 2000, 51:25-29.
66. Killackey E., Yung A.R. Effectiveness of early intervention in psychosis. Curr Opin Psychiatry 2007, 20:121-125.
67. Srihari V.H., Shah J., Keshavan M.S. Is early intervention for psychosis feasible and effective?. Psychiatr Clin N Am 2012, 35:613-631.
68. Wykes T., et al. A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes. Am J Psychiatry 2011, 168:472-485.
69. Bowie C.R., et al. Cognitive remediation in schizophrenia: efficacy and effectiveness in patients with early versus long-term course of illness. Early Interv Psychiatry 2014, 8:32-38.
70. Goldberg T.E., et al. Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test. Arch Gen Psychiatry 1987, 44:1008-1014.
71. Velligan D.I., et al. A randomized controlled trial comparing cognitive behavior therapy, cognitive adaptation training, their combination and treatment as usual in chronic schizophrenia. Schizophr Bull 2014.
72. Velligan D.I., et al. Randomized controlled trial of the use of compensatory strategies to enhance adaptive functioning in outpatients with schizophrenia. Am J Psychiatry 2000, 157:1317-1323.
73. Rauchensteiner S., et al. Test-performance after cognitive training in persons at risk mental state of schizophrenia and patients with schizophrenia. Psychiatry Res 2011, 185:334-339.
74. Hooker C.I., et al. A pilot study of cognitive training in clinical high risk for psychosis: initial evidence of cognitive benefit. Schizophr Res 2014, 157:314-316.
75. Fisher M., et al. Neuroplasticity-based auditory training via laptop computer improves cognition in young individuals with recent onset schizophrenia. Schizophr Bull 2014.
76. Ueland T., Rund B.R. Cognitive remediation for adolescents with early onset psychosis: a 1-year follow-up study. Acta Psychiatr Scand 2005, 111:193-201.
77. Ostergaard Christensen T., et al. Cognitive remediation combined with an early intervention service in first episode psychosis. Acta Psychiatr Scand 2014, 130:300-310.
78. Wykes T., et al. Cognitive remediation therapy (CRT) for young early onset patients with schizophrenia: an exploratory randomized controlled trial. Schizophr Res 2007, 94:221-230.
79. Lewandowski K.E., et al. Is cognitive enhancement therapy equally effective for patients with schizophrenia and schizoaffective disorder?. Schizophr Res 2011, 125:291-294.
80. Piskulic D., et al. Pilot study of cognitive remediation therapy on cognition in young people at clinical high risk of psychosis. Psychiatry Res 2014, 10.1016/j.psychres.2014.10.021i.
81. Eack S.M., et al. Effects of cognitive enhancement therapy on employment outcomes in early schizophrenia: results from a two-year randomized trial. Res Soc Work Pract 2011, 21:32-42.
82. Hansen J.P., et al. Cognitive adaptation training combined with assertive community treatment: a randomised longitudinal trial. Schizophr Res 2012, 135:105-111.
83. Drake R.J., et al. A naturalistic, randomized, controlled trial combining cognitive remediation with cognitive-behavioural therapy after first-episode non-affective psychosis. Psychol Med 2014, 44:1889-1899.
84. Addington J., Saeedi H., Addington D. The course of cognitive functioning in first episode psychosis: changes over time and impact on outcome. Schizophr Res 2005, 78:35-43.
85. Allott K.A., et al. Feasibility and acceptability of cognitive adaptation training for first-episode psychosis. Early Interv Psychiatry 2014, (in press).
86. Lysaker P.H., et al. Social skills at work. Deficits and predictors of improvement in schizophrenia. J Nerv Ment Dis 1995, 183:688-692.
87. Green M.F., et al. Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the "right stuff"?. Schizophr Bull 2000, 26:119-136.
88. Prouteau A., et al. Cognitive predictors of psychosocial functioning outcome in schizophrenia: a follow-up study of subjects participating in a rehabilitation program. Schizophr Res 2005, 77:343-353.
89. Allott K.A., et al. The relative contribution of neurocognition and social cognition to 6-month vocational outcomes following Individual Placement and Support in first-episode psychosis. Schizophr Res 2013, 150:136-143.
90. Bartholomeusz C.F., et al. Social cognition training as an intervention for improving functional outcome in first-episode psychosis: a feasibility study. Early Interv Psychiatry 2013, 7:421-426.
91. Cacciotti-Saija C., et al. A double-blind randomized controlled trial of oxytocin nasal spray and social cognition training for young people with early psychosis. Schizophr Bull 2014.
92. Green M.F., et al. Social cognition in schizophrenia. Part 1: performance across phase of illness. Schizophr Bull 2012, 38:854-864.
93. Bora E., Yucel M., Pantelis C. Theory of mind impairment: a distinct trait-marker for schizophrenia spectrum disorders and bipolar disorder?. Acta Psychiatr Scand 2009, 120:253-264.
94. Bora E., Pantelis C. Theory of mind impairments in first-episode psychosis, individuals at ultra-high risk for psychosis and in first-degree relatives of schizophrenia: systematic review and meta-analysis. Schizophr Res 2013, 144:31-36.
95. Blakemore S.J. The social brain in adolescence. Nat Rev Neurosci 2008, 9:267-277.
96. Wykes T., et al. Effects on the brain of a psychological treatment: cognitive remediation therapy: functional magnetic resonance imaging in schizophrenia. Br J Psychiatry 2002, 181:144-152.
97. Subramaniam K., et al. Computerized cognitive training restores neural activity within the reality monitoring network in schizophrenia. Neuron 2012, 73:842-853.