Metastasis-promoting role of extravasated platelet activation in tumor

Journal of Surgical Research

Volumn 193, Issue 1, 2015, Pages 289-294

  Miyashita, Tomoharu ^a   Tajima, Hidehiro ^a   Makino, Isamu ^a   Nakagawara, Hisatoshi ^a   Kitagawa, Hirohisa ^a   Fushida, Sachio ^a   Harmon, John W ^b   Ohta, Tetsuo ^a  

^a KANAZAWA UNIVERSITY HOSPITAL   (Japan)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epithelial to mesenchymal transition; Metastasis; Pancreatic cancer; Platelet aggregation

Indexed keywords

GLYCOPROTEIN IB ALPHA; PROTEIN; SNAIL1 PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN; SNAIL FAMILY TRANSCRIPTION FACTORS; THROMBIN RECEPTOR; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; CANCER SURGERY; CLINICAL ARTICLE; CLINICAL FEATURE; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE ACTIVATION; TUMOR INVASION; TUMOR MICROENVIRONMENT; BLOOD; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PANCREAS; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; SECONDARY; THROMBOCYTE; THROMBOCYTE AGGREGATION;

ADULT; AGED; BLOOD PLATELETS; CADHERINS; CARCINOMA, PANCREATIC DUCTAL; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; MALE; MIDDLE AGED; PANCREAS; PANCREATIC NEOPLASMS; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; TRANSCRIPTION FACTORS; TUMOR MICROENVIRONMENT;

EID: 84925030905     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2014.07.037     Document Type: Article

References (43)

1. Lowenfels AB, Maisonneuve P. Epidemiology and prevention of pancreatic cancer. Jpn J Clin Oncol 2004;34:238.
2. Karamitopoulou E. Role of epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma: is tumor budding the missing link? Front Oncol 2013;3:221.
3. Hidalgo M. Pancreatic cancer. N Engl J Med 2010;362:1605.
4. Sharma C, Eltawil KM, Renfrew PD, Walsh MJ, Molinari M. Advances in diagnosis, treatment and palliation of pancreatic carcinoma: 1990-2010. World J Gastroenterol 2011; 17:867.
5. Li Y, Kong D, Ahmad A, Bao B, Sarkar FH. Pancreatic cancer stem cells: emerging target for designing novel therapy. Cancer Lett 2013;338:94.
6. Krantz SB, Shields MA, Dangi-Garimella S, Munshi HG, Bentrem DJ. Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression. J Surg Res 2012;173:105.
7. Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelialmesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006;172:973.
8. Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymal transitions in development and disease. Cell 2009;139:871.
9. Yang AD, Camp ER, Fan F, et al. Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. Cancer Res 2006;66:46.
10. von Burstin J, Eser S, Paul MC, et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. Gastroenterology 2009;137:361. 371.e361-365.
11. Cavallaro U, Christofori G. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer 2004;4:118.
12. Medici D, Hay ED, Olsen BR. Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-Tcell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell 2008;19:4875.
13. de Herreros AG, Peiró S, Nassour M, Savagner P. Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J Mammary Gland Biol Neoplasia 2010; 15:135.
14. Oft M, Heider KH, Beug H. TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol 1998;8: 1243.
15. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219:983.
16. Kitadai Y. Cancer-stromal cell interaction and tumor angiogenesis in gastric cancer. Cancer Microenviron 2010; 3:109.
17. Almholt K, Nielsen BS, Frandsen TL, Brü nner N, Danø K, Johnsen M. Metastasis of transgenic breast cancer inplasminogen activator inhibitor-1 gene-deficient mice. Oncogene 2003;22:4389.
18. Maillard CM, Bouquet C, Petitjean MM, et al. Reduction of brain metastases in plasminogen activator inhibitor-1-deficient mice with transgenic ocular tumors. Carcinogenesis 2008;29:2236.
19. Hogan NM, Joyce MR, Murphy JM, et al. Impact of mesenchymal stem cell secreted PAI-1 on colon cancer cell migration and proliferation. Biochem Biophys Res Commun 2013;435:574.
20. Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004;91:4.
21. Kellouche S, Mourah S, Bonnefoy A, et al. Platelets, thrombospondin-1 and human dermal fibroblasts cooperate for stimulation of endothelial cell tubulogenesis through VEGF and PAI-1 regulation. Exp Cell Res 2007; 313:486.
22. Labelle M, Begum S, Hynes RO. Direct signaling between platelets and cancer cells induces an epithelialmesenchymal-like transition and promotes metastasis. Cancer Cell 2011;20:576.
23. Anitua E, Sanchez M, Nurden AT, et al. Reciprocal actions of platelet-secreted TGF-beta1 on the production of VEGF and HGF by human tendon cells. Plast Reconstr Surg 2007; 119:950.
24. Lowe KL, Navarro-Nunez L, Watson SP. Platelet CLEC-2 and podoplanin in cancer metastasis. Thromb Res 2012; 129(Suppl 1):S30.
25. Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW, Mehta Z. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet 2012;379:1591.
26. Liao X, Lochhead P, Nishihara R, et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N Engl J Med 2012;367:1596.
27. Sahasrabuddhe VV, Gunja MZ, Graubard BI, et al. Nonsteroidal anti-inflammatory drug use, chronic liver disease, and hepatocellular carcinoma. J Natl Cancer Inst 2012;104:1808.
28. Yang MH, Hsu DS, Wang HW, et al. Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol 2010;12:982.
29. Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 2011;331:1559.
30. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646.
31. Iwatsuki M, Mimori K, Yokobori T, et al. Epithelialmesenchymal transition in cancer development and its clinical significance. Cancer Sci 2010;101:293.
32. Foroni C, Broggini M, Generali D, Damia G. Epithelialmesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact. Cancer Treat Rev 2012; 38:689.
33. Shiao SL, Ganesan AP, Rugo HS, Coussens LM. Immune microenvironments in solid tumors: new targets for therapy. Genes Dev 2011;25:2559.
34. Catalano V, Turdo A, Di Franco S, Dieli F, Todaro M, Stassi G. Tumor and its microenvironment: a synergistic interplay. Semin Cancer Biol 2013;23:522.
35. Hotz B, Arndt M, Dullat S, Bhargava S, Buhr HJ, Hotz HG. Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer. Clin Cancer Res 2007;13:4769.
36. Tajima H, Ohta T, Kitagawa H, et al. Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44. Oncol Lett 2012;3:1186.
37. Bambace NM, Holmes CE. The platelet contribution to cancer progression. J Thromb Haemost 2011;9:237.
38. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860.
39. Assoian RK, Komoriya A, Meyers CA, Miller DM, Sporn MB. Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization. J Biol Chem 1983;258:7155.
40. Gay LJ, Felding-Habermann B. Contribution of platelets to tumour metastasis. Nat Rev Cancer 2011;11:123.
41. Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med 2013;19:1423.
42. Sierko E, Wojtukiewicz MZ. Inhibition of platelet function: does it offer a chance of better cancer progression control? Semin Thromb Hemost 2007;33:712.
43. Erpenbeck L, Schön MP. Deadly allies: the fatal interplay between platelets and metastasizing cancer cells. Blood 2010; 115:3427.